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  • genes
  • The pre-implantation development of these embryos is normal and the stabilised β-catenin fails to travel to the nucleus to activate Wnt target genes. (biologists.org)
  • The extra-embryonic region of post-implantation embryos also develops normally, but embryonic endoderm cells prematurely express Wnt target genes and undergo a premature epithelial-mesenchymal transition. (biologists.org)
  • We did so, because most studies into (zebrafish) embryogenesis are typically using pools of staged embryos plus quite dispersed time points, and we reasoned that a high-resolution time course could provide much insight into the true dynamics of the individual genes of the embryonic transcriptome. (redhothealthcare.com)
  • embryo
  • Human embryo development is a complex process. (springer.com)
  • The zygote undergoes mitotic divisions with no significant growth (a process known as cleavage ) and cellular differentiation , leading to development of a multicellular embryo. (wn.com)
  • The marvelous development of the human embryo should make everyone a creationist, it seems to me, but evolutionists say that the so-called 'gill slits, yolk sac, and tail' are useless evolutionary leftovers (vestiges) that virtually 'prove' we evolved from fish, reptiles, and apes. (sounddoctrine.net)
  • In areas where levels of a protein important for the development of the head were high (shown here in red, with brighter color indicating the presence of more protein) there was less enzyme available to act upon a different protein (shown here in green) that is important for the development of the ends of the embryo, including the tail. (princeton.edu)
  • The second protein plays a significant role in the chemical circuit that controls the development of the ends of the embryo, including the tail. (princeton.edu)
  • Early on in development, the mass of undifferentiated cells that make up the embryo take the first steps in deciding how to arrange themselves into component parts to eventually go on to form a fully developed body. (thaindian.com)
  • 30 h -Amnion (embryonic membrane around embryo) begins. (backyardchickens.com)
  • The resulting combination of proteins will transform clusters of cells into early embryo tissues that will each develop into multiple fetal and adult tissues later in development (note: this happens after each nucleus becomes wrapped with its own cell membrane). (wikipedia.org)
  • As recently as the 18th century, the prevailing notion in western human embryology was preformation: the idea that semen contains an embryo - a preformed, miniature infant, or homunculus - that simply becomes larger during development. (wikipedia.org)
  • RNAs
  • The let-7 RNA was found to be conserved in many species, leading to the suggestion that let-7 RNA and additional "small temporal RNAs" might regulate the timing of development in diverse animals, including humans. (wikipedia.org)
  • The many RNAs of this class resembled the lin-4 and let-7 RNAs, except their expression patterns were usually inconsistent with a role in regulating the timing of development. (wikipedia.org)
  • ventral
  • Precursors of inhibitory interneurons transplanted from the medial ganglionic eminence of the ventral embryonic forebrain into the juvenile or adult rodent cortex migrate from the graft site and become dispersed throughout the recipient tissue (shown as small red dots in the transplanted hemisphere in a cross section of the rodent brain, upper left). (sciencemag.org)
  • mice
  • At embryonic (E) day 18.5, SMGs from wild-type mice showed duct branching morphogenesis and differentiation of tubule ductal cells into tubule secretory cells. (nih.gov)
  • For mice, by embryonic day 7.5 (E7.5), MACF1 is expressed in the headfold and primitive streak, and by E8.5 the protein is expressed in neuronal tissues and the foregut. (wikipedia.org)
  • MFN2 knockout mice die at embryonic day 11.5 due to a defect in the giant cell layer of the placenta. (wikipedia.org)
  • Growth
  • In recent years, Kipps and others have become increasingly interested in the role of ROR1 plays in the growth of cancer - and whether the protein might provide new options for stopping development of the disease. (ucsd.edu)
  • Segmentation is apparently specified by the same gene as in other groups of animals, and is activated in each case, during embryonic development, at the rear border of each segment and in the growth zone of the stub feet. (wikipedia.org)
  • germ
  • One of the first, and arguably most important, steps in development is the allocation of cells into three germ layers-ectoderm, mesoderm , and endoderm-that give rise to all tissues and organs in the body," explains Mark Mercola, Ph.D., professor and director of Sanford-Burnham's Muscle Development and Regeneration Program in the Sanford Children's Health Research Center. (medicalxpress.com)
  • larval
  • These groups published back-to-back papers on the lin-4 gene, which was known to control the timing of C. elegans larval development by repressing the lin-14 gene. (wikipedia.org)
  • cells
  • They often can be found to have features of embryonic cells. (ucsd.edu)
  • Results published March 9 in the journal Current Biology, however, suggest that competition for the MAPK enzyme among proteins in different pathways influences which signals are sent to cells, establishing a biochemical mode of signal integration that adds a previously unrecognized layer of complexity and control to embryonic development. (princeton.edu)
  • When the cells fail to associate in a manner that is not part of the normal course of development, severe diseases can occur. (wikipedia.org)
  • role
  • The goal of this study was to determine the role of NFIB during SMG development. (nih.gov)
  • Several targets for miR-184 have been described, including that of mediators of neurological development, apoptosis and it has been suggested that miR-184 plays an essential role in development. (wikipedia.org)
  • cancer
  • MAPK signaling pathways, or chemical networks that involve the enzyme, are critical for normal development, and defects in these pathways can lead to severe developmental disorders and cancer. (princeton.edu)
  • organ
  • NFIB (nuclear factor I B) is a NFI transcription factor family member, which is essential for the development of a variety of organ systems. (nih.gov)
  • control
  • Our findings provide a new window through which to look at epigenetic control," Yeh said, "and how epigenetics and development are unexpectedly tied together by the SUMO/SENP2 system. (redorbit.com)
  • genes
  • The pre-implantation development of these embryos is normal and the stabilised β-catenin fails to travel to the nucleus to activate Wnt target genes. (biologists.org)
  • The extra-embryonic region of post-implantation embryos also develops normally, but embryonic endoderm cells prematurely express Wnt target genes and undergo a premature epithelial-mesenchymal transition. (biologists.org)
  • We did so, because most studies into (zebrafish) embryogenesis are typically using pools of staged embryos plus quite dispersed time points, and we reasoned that a high-resolution time course could provide much insight into the true dynamics of the individual genes of the embryonic transcriptome. (redhothealthcare.com)
  • enzymes
  • The book's somewhat controversial argument is that evolution in animals (though no doubt similar processes occur in other organisms) proceeds mostly by modifying the way that regulatory genes, which do not code for structural proteins (such as enzymes), control embryonic development. (wikipedia.org)
  • gene
  • 8. How the Butterfly Got Its Spots Echoing the titles of Rudyard Kipling's Just So Stories, Carroll shows how butterfly wing patterns evolved, including his discovery of the role of the Distal-less gene there, until then known in limb development. (wikipedia.org)
  • mouse
  • Using mouse embryonic fibroblasts from C/EBPα-null mice, we have determined that the latter transcription factor may not solely mediate the inhibitory effect of palmitate on adiponectin transcription leaving PPARγ as a likely target of palmitate. (pubmedcentralcanada.ca)
  • Using a previously established mouse ES-cell-based system that recapitulates the development of the ectoderm lineage we have identified a transient population that is consistent with definitive ectoderm. (biologists.org)
  • diversity
  • We will study the evolutionary history of the plant kingdom to better understand the selective forces that have shaped plants' development and led to the diversity of forms in existence today. (psu.edu)
  • provide
  • Thus, protocols to isolate and culture individual organs of interest are essential to provide a method of both visualizing changes in development and allowing novel treatment strategies. (jove.com)
  • The "selective use of data", cherry picking, is identified as a notable form of scientific abuse by the Pacific Institute, an organization created to provide independent research and policy analysis on issues at the intersection of development, environment, and security. (wikipedia.org)