• Ecdysone receptor Ecdybase, The Ecdysone Handbook - a free online ecdysteroids database de Loof A (2006). (wikipedia.org)
  • Ecdysteroid receptor from the American lobster Homarus americanus: EcR/RXR isoform cloning and ligand-binding properties. (scilifelab.se)
  • In arthropods, ecdysteroids regulate molting by activating a heterodimer formed by the ecdysone receptor (EcR) and retinoid X receptor (RXR). (scilifelab.se)
  • Dual-luciferase reporter assays were used to assess the role of miRNA let-7 in ecdysteroid receptor (ECR) biology. (biomedcentral.com)
  • Although Ecdysone receptor -encoded nuclear receptor isoforms are the only known ecdysteroid receptors, we show that the Ecdysone receptor gene is not required for furrow function. (biologists.com)
  • DHR78 , which encodes another candidate ecdysteroid receptor, is also not required. (biologists.com)
  • The progression of the morphogenetic furrow in the developing Drosophila eye is an early metamorphic, ecdysteroid-dependent event. (biologists.com)
  • 2. Drosophila Kdm4 demethylases in histone H3 lysine 9 demethylation and ecdysteroid signaling. (nih.gov)
  • Neural factors that stimulate ecdysteroid synthesis by the larval ring gland of Drosophila m. (uncg.edu)
  • Ecdysone is a steroid hormone of the ecdysteroids family which is found in animals (vertebrates and invertebrates) and in plants. (bioquote.com)
  • HR3 mRNA levels in embryos also varied co-incident with ecdysteroid levels. (nih.gov)
  • The Ecdysoneless (ecd1ts) Mutation Disrupts Ecdysteroid Synthesis Autonomously in the Ring G. (uncg.edu)
  • Hartfelder K., Köstlin K., Hepperle C. (1995) Ecdysteroid-dependent protein synthesis in caste-specific development of the larval honey bee ovary, Roux's Arch. (apidologie.org)
  • Expression and ecdysteroid responsiveness of the nuclear receptors HR3 and E75 in the crustacean Daphnia magna. (nih.gov)
  • We tested the hypothesis that crustaceans express the nuclear receptors HR3 (ortholog to vertebrate ROR) and E75 (ortholog to vertebrate rev-erb) in response to ecdysteroid signaling. (nih.gov)
  • Ecdysteroids initiate signaling along multiple pathways that regulate various aspects of development, maturation, and reproduction in arthropods. (nih.gov)
  • Feldlaufer M.F., Herbert E.W., Svoboda J.A., Thompson M.J., Lusby W.R. (1985) Makisterone A - the major ecdysteroid from the pupa of the honey bee, Apis mellifera , Insect Biochem. (apidologie.org)
  • Of the three major metabolites, the two carboxylic acid metabolites are likely to be significantly less toxic than tebufenozide to fish and daphnids and are not insecticidally active, whereas the ketone metabolite has some ecdysteroid activity, but significantly less than tebufenozide. (apvma.gov.au)
  • These studies establish the molecular basis for investigation of lobster ecdysteroid signaling and signal disruption by environmental chemicals. (scilifelab.se)
  • Moreover, loss-of-function by transient RNAi targeting cyp307a1 disrupted ecdysteroid production demonstrating that this gene is required for ecdysteroid biosynthesis in Anopheles gambiae. (nih.gov)
  • To substantiate a role of ecdysteroids in the expression of HR3, daphnids were continuously exposed to 20-hydroxyecdysone and changes in gene expression were measured. (nih.gov)
  • A plant genus in the family Asparagaceae that contains ECDYSTEROIDS and is an ingredient of Siotone. (bvsalud.org)
  • In conclusion, the in vitro cell reporter assay, based on NiEcR-LBD/CrcRXR-LBD heterodimerization in Hi5 cells and validated with the natural ecdysteroid hormone PonA, represents a useful tool for the screening of putative EDCs. (ilvo.be)
  • HR3 levels were comparable to those of E75 during the initial phases of the adult molt cycle but were elevated approximately 30-fold at a time in the cycle co-incident with the pre-molt surge in ecdysteroid levels. (nih.gov)
  • This database has been designed as a tool to help the scientific community in research on ecdysteroids. (ecdybase.org)