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  • shown
  • Dopamine beta-monooxygenase is shown to catalyze the oxidation of N,N,N',N'-tetramethyl-1,4-phenylenediamine (TMPD) to its cation radical in the presence of a regular substrate and molecular oxygen. (wichita.edu)
  • dopaminergic
  • Abnormal dopamine receptor signaling and dopaminergic nerve function is implicated in several neuropsychiatric disorders. (wikipedia.org)
  • To gain more insight into the dopaminergic system of amphibians and the evolution of catecholaminergic systems in vertebrates in general, the distribution of dopamine and tyrosine hydroxylase immunoreactivity was studied in the brains of the anuran Rana ridibunda and the urodele Pleurodeles waltlii. (google.com)
  • Dopamine dysregulation syndrome (DDS) is a dysfunction of the reward system observed in some individuals taking dopaminergic medications for an extended length of time. (wikipedia.org)
  • This results in increased extracellular concentrations of dopamine and increase in dopaminergic neurotransmission. (wikipedia.org)
  • selective for dopamine
  • Piribedil (Pronoran and Trivastal - used to treat PD/RLS) Pramipexole (Mirapex and Sifrol - used to treatPD/RLS) Propylnorapomorphine (used to treat PD/RLS) Quinagolide (Norprolac - used to treat PD/RLS) Ropinirole (Requip - used to treat PD/RLS) Rotigotine (Neupro - used to treat PD/RLS) Roxindole (used to treat PD/RLS) Sumanirole (used to treat PD/RLS) Some, such as fenoldopam, are selective for dopamine receptor D1. (wikipedia.org)
  • hydrochloride
  • Dopamine hydrochloride is a type of medicine called a sympathomimetic inotrope. (netdoctor.co.uk)
  • Dopamine Hydrochloride Injection, USP is a clear, practically colorless, aqueous, additive solution for intravenous infusion after dilution. (factbites.com)
  • Because of the increased stability and water-solubility of the protonated form, dopamine is supplied for chemical or pharmaceutical use as dopamine hydrochloride-that is, the hydrochloride salt that is created when dopamine is combined with hydrochloric acid. (wikipedia.org)
  • In dry form, dopamine hydrochloride is a fine colorless powder. (wikipedia.org)
  • inhibitors
  • It is particularly of note that the mechanism of action at DAT for dopamine releasers/substrates is entropy-driven (i.e. hydrophobic), whereas for dopamine re-uptake inhibitors it is enthalpy-driven (i.e. conformational change). (wikipedia.org)
  • tyrosine
  • Diets high in sugar and saturated fats can suppress dopamine, and a lack of protein in a person's diet could mean they do not have enough l-tyrosine, which is an amino acid that helps to build dopamine in the body. (medicalnewstoday.com)
  • Comparative analysis of dopamine and tyrosine hydroxylase immunoreactivities in the brain of two amphibians, the anuran Rana ridibunda and the urodele Pleurodeles waltlii. (google.com)
  • Dopamine is synthesized in the body (mainly by nervous tissue and adrenal glands) first by the dehydration of the amino acid tyrosine to DOPA by tyrosine hydroxylase and then by the decarboxylation of DOPA by aromatic-L-amino-acid decarboxylase. (factbites.com)
  • Dopamine is one of the biogenic amines, neurotransmitters that are derived from amino acids, and is a member of the group called catecholamines that are derived from the amino acid, tyrosine . (factbites.com)
  • DRD5
  • To investigate whether dopamine receptor D5 (DRD5) T978C polymorphism is associated with the risk of developing motor fluctuations in PD, we studied this polymorphism in a case-control study of 120 subjects with sporadic PD and 110 control subjects. (factbites.com)
  • amino acid
  • Dopamine is synthesized in the body (mainly nervous tissue and adrenal glands) by the decarboxylation of DOPA by aromatic-L-amino-acid decarboxylase. (factbites.com)
  • medication
  • Dopamine itself is available as a manufactured medication for intravenous injection: although it cannot reach the brain from the bloodstream, its peripheral effects make it useful in the treatment of heart failure or shock, especially in newborn babies. (wikipedia.org)
  • Dopamine, sold under the brandname Intropin among others, is a medication most commonly used in the treatment of very low blood pressure, a slow heart rate that is causing symptoms, and, if epinephrine is not available, cardiac arrest. (wikipedia.org)
  • induce
  • However, the indirect biosynthesis of phospholipid esters with dopamine may be possible, as dopamine can induce the aminolysis of the glycerol-fatty acid bonds in phospholipid chains (arachidonoyl, palmitoyl, linoleyl, etc. (wikipedia.org)
  • mechanism
  • These results are interesting as they demonstrate a mechanism in which dopamine, normally increased at times of stimulation, can directly inhibit production and release of a molecule, melatonin, that induces drowsiness and prepares the body for sleep," explained Dr McCormick. (redorbit.com)
  • attention-deficit
  • Restless legs syndrome and attention deficit hyperactivity disorder (ADHD) are associated with decreased dopamine activity. (wikipedia.org)
  • DAT is implicated in a number of dopamine-related disorders, including attention deficit hyperactivity disorder, bipolar disorder, clinical depression, and alcoholism. (wikipedia.org)
  • BØRNS
  • Dopamine is the debut studio album by American singer-songwriter Børns, released on October 16, 2015 by Interscope Records. (wikipedia.org)
  • behavior
  • The brain includes several distinct dopamine pathways, one of which plays a major role in reward-motivated behavior. (wikipedia.org)
  • Simultaneously, the ventral frontostriatal circuit will experience an overdose of dopamine that will lead to increased impulsive behavior. (wikipedia.org)
  • disorders
  • Low dopamine is linked to numerous mental health disorders but does not directly cause these conditions. (medicalnewstoday.com)
  • Dopamine disorders in the frontal lobes can cause a decline in neurocognitive function, particularly those linked to the frontal lobes , such as memory , attention and problem solving . (factbites.com)
  • and has been used in the treatment of disorders characterized by a dopamine imbalance. (wikipedia.org)
  • molecule
  • A dopamine molecule consists of a catechol structure (a benzene ring with two hydroxyl side groups) with one amine group attached via an ethyl chain. (wikipedia.org)
  • release
  • Most abused drugs cause the release of dopamine and this is thought to contribute to their addictive properties. (psychologytoday.com)
  • Listening to their favorite piece of spine-tingling music, the eight volunteers showed a rush of physical activity and also unlocked a release of dopamine in the striatum area of the brain. (redorbit.com)
  • With the exception of the blood vessels, dopamine in each of these peripheral systems is synthesized locally and exerts its effects near the cells that release it. (wikipedia.org)
  • In the cytosol, other transporters sequester the dopamine into vesicles for storage and later release. (wikipedia.org)
  • citation needed] In November 2007, it was announced Dopamine Records will release the latest music from Boston's Hooray For Earth. (wikipedia.org)
  • A dopamine releasing agent (DRA) is a type of drug which induces the release of dopamine in the body and/or brain. (wikipedia.org)