• viral
  • No correlation with fatigue was found with the following variables: age, liver function tests, viral load, degree of liver disease on biopsy or resting energy expenditure. (natap.org)
  • Certain viral diseases have been shown to mutate more rapidly in selenium-deficient hosts producing more virulent viruses. (wikipedia.org)
  • Daily supplementation was found to suppress progression of HIV-1 viral burden and provide indirect improvement to CD4 cell counts. (wikipedia.org)
  • symptom
  • reported on the relationship of circulating leptin with fatigue in patients with chronic hepatitis C. Approximately 50% of the hepatitis C patients in this study listed fatigue as the worst or initial symptom of the disease. (natap.org)
  • Ataxia, as a symptom has been known since mid 19th century and the heterogenous group of diseases now known as spinocerebellar ataxias was the subject of extensive research in the latter part of that century. (wikipedia.org)
  • incidence
  • The appearance of people with the disease is depicted in: Carvings of Queen of Punt (Egypt), as noted above The Italian statue The Warrior of Capestrano, as noted above Donna Leon's crime novel, Beastly Things (2012), wherein the protagonist investigates the murder of a man who had the condition, which Brunetti learns has a high incidence in Italy Lipomatosis List of cutaneous conditions Madelung's deformity Rapini, Ronald P. (wikipedia.org)
  • Furthermore, selenium yeast has been used in a wide range of studies aimed at examining the importance of selenium status in the incidence and progression of a variety of infectious and degenerative diseases. (wikipedia.org)
  • Alzheimer's
  • Researchers say vitamin E might slow the progression of mild-to-moderate Alzheimer's disease - the first time any treatment has been shown to alter the course of dementia at that stage. (heraldnet.com)
  • This is truly a breakthrough paper and constitutes what we have been working toward for nearly three decades: the first truly disease-modifying intervention for Alzheimer's," said Dr. Sam Gandy of Mount Sinai School of Medicine in New York. (heraldnet.com)
  • Heather Snyder, director of medical and scientific operations for the Alzheimer's Association, said the group's position is that "no one should take vitamin E for Alzheimer's disease or other memory issues except under the supervision of a physician," because it can interfere with blood thinners, cholesterol drugs and other medicines. (heraldnet.com)
  • In the September Journal of Alzheimer's Disease, the authors report a validation of sorts for this approach. (alzforum.org)
  • She is known for her work on neurological disorders that affect learning and memory, particularly for her research on Alzheimer's disease and the role of CDK5 and chromatin remodeling in the progression of the disease. (wikipedia.org)
  • Tsai also discovered that while Cdk5 activity is essential to proper brain development and function, overexpression of Cdk5 was associated with Alzheimer's disease. (wikipedia.org)
  • In recent work, Tsai has elucidated the role of structural and epigenetic mechanisms in Alzheimer's disease, showing in two 2015 studies that the DNA breakage necessary to learning was also responsible for cognitive decline, due to decline in DNA repair systems with age, and that the genetic component of Alzheimer's primarily affects the regulatory circuitry of immune processes, rather than neuronal processes as expected. (wikipedia.org)
  • In 2016, Tsai demonstrated that visual stimulation of mice with an LED flashing at 40 hertz substantially reduces the beta amyloid plaques associated with Alzheimer's disease, likely by inducing gamma oscillations. (wikipedia.org)
  • lesions
  • For decades, clinicians treating multiple sclerosis (MS) have interpreted the appearance of new or expanding brain lesions on magnetic resonance imaging (MRI) scans as a sign that a patient's disease is getting worse. (news-medical.net)
  • Patients with MS receive MRI scans as part of their routine care so that doctors can track the appearance of new lesions and the enlargement of existing ones, typically seen as indicators of disease progression. (news-medical.net)
  • Temporal progression of common root rot [Cochliobolus sativus] lesions on subcrown internodes of wheat and barley cultivars" (PDF). (wikipedia.org)
  • Silicosis (previously miner's phthisis, grinder's asthma, potter's rot and other occupation-related names) is a form of occupational lung disease caused by inhalation of crystalline silica dust, and is marked by inflammation and scarring in the form of nodular lesions in the upper lobes of the lungs. (wikipedia.org)
  • immune
  • Occasional heroin use by HIV-positive patients may be harmful to the immune system and worsen HIV disease, compared to persistent or no heroin use, thus, suggesting that heroin withdrawal may be particularly harmful to the immune system, according to researchers at Yale and Boston University and their Russian collaborators. (medindia.net)
  • progresses
  • Ataxia refers to a lack of coordinated muscle movements that include gait abnormality and is the cerebellar sign that typifies all SCA types, though individuals with SCA1 also develop pyramidal and bulbar signs as the disease progresses. (wikipedia.org)
  • AIDS
  • Some LTNPs are infected with HIV that inefficiently replicates whilst others are infected with HIV that is virally fit and replicates normally, but the infected individual has had a strong and broad set of HIV-specific humoral and cell-mediated responses that seems to delay the progression to AIDS. (wikipedia.org)
  • genes
  • An alternative method is to look for genes that associate with an endophenotype, or an inherited phenotype linked to the disease. (alzforum.org)
  • Endophenotypes have been used to find genes for conditions such as osteoporosis and heart disease, but they have not yet been widely employed in AD studies. (alzforum.org)
  • First author John Kauwe correlated levels of CSF Aβ and tau with known AD-associated genetic polymorphisms, hoping to glean clues about how the genes contribute to the disease. (alzforum.org)
  • colleagues
  • Our data [suggest] that niclosamide and/or its analogs could have therapeutic benefit in slowing down Parkinson's disease," write Barini and colleagues. (medicalnewstoday.com)
  • Pellecchia and colleagues hypothesize that interactions between motor neurons and astrocytes are responsible at least in part for the progression of motor neuron death in ALS patients. (sciforums.com)
  • long-term
  • Another subset of individuals who are persistently infected with HIV-1, but show no signs of disease progression for over 12 years and remain asymptomatic are classified as Long Term Non-Progressors (LTNP). (wikipedia.org)
  • patients
  • Also, 48% of the patients did not develop progressive disease. (pharmacytimes.com)
  • Fatigue can be debilitating and frustrating to patients and physicians as its presence is difficult to explain in the context of the overall disease process. (natap.org)
  • risk
  • This finding was secondary to the reduction in risk of death from liver disease in the treated group as the risk of dying from non-liver related causes was unchanged in both groups. (natap.org)
  • treatment
  • Scientists from the ALS Therapy Development Institute announced today the publication of the paper, "Guanabenz treatment accelerates disease in a mutant SOD1 mouse model of ALS," in the peer-reviewed journal PLOS ONE . (prweb.com)
  • The information should not be used for either diagnosis or treatment or both for any health related problem or disease. (medindia.net)
  • Many efforts to find a treatment for Alzheimer disease have focused on discovering a way to reduce Aβ, with largely disappointing results so far. (alzforum.org)
  • people
  • The National Institutes of Health (NIH) estimate that around 500,000 individuals in the United States have Parkinson's disease , and that each year, about 50,000 people are diagnosed with the condition. (medicalnewstoday.com)
  • It is estimated that over 15 million people are suffering from the disease and many more are harboring the dreaded Human Immunodeficiency Virus (HIV). (medindia.net)
  • Also, some people may lose one kidney due to a disease or accident, or they may donate a kidney to someone else. (hcvadvocate.org)
  • The primary purpose of the study will be to look for biological biomarkers to determine which people with gum disease will have a worsening of the disease. (clinicaltrials.gov)
  • processes
  • The rod photoreceptor cells, which are responsible for low-light vision and are orientated in the retinal periphery, are the retinal processes affected first during non-syndromic forms of this disease. (wikipedia.org)
  • contribute
  • Antioxidants help protect cells from damage that can contribute to other diseases, says the federal Office on Dietary Supplements. (heraldnet.com)
  • delay
  • RP associated with hypogonadism, and developmental delay with an autosomal recessive inheritance pattern is seen with Bardet-Biedl syndrome Other conditions include neurosyphilis, toxoplasmosis and Refsum's disease. (wikipedia.org)
  • known
  • This etiology has been demonstrated for both the Coxsackie B virus (associated with a Se-deficiency-related cardiomyopathy known as Keshan disease) and the influenza virus. (wikipedia.org)
  • Phytophthora ramorum is the oomycete plant pathogen known to cause the disease sudden oak death (SOD). (wikipedia.org)
  • The disease is known to exist in California's coastal region between Big Sur (in Monterey County) and southern Humboldt County. (wikipedia.org)
  • found
  • Overall, the study found that intrafamilial transmission of hepatitis C is uncommon and that it is not increased by the presence of HIV disease. (natap.org)
  • Levels
  • Finding that tau levels are connected to disease progression fits well with previous research, said Henrik Zetterberg at Brigham and Women's Hospital, Boston, Massachusetts. (alzforum.org)
  • However
  • However, A3 and A11 can process and load antigens even when proteosome activity is diminished suggesting an alternative mechanism for loading which may benefit in recovery from some disease but impair recovery of others. (wikipedia.org)
  • development
  • This paper highlights the importance of comprehensive preclinical testing, such as in animal models of the disease," said Fernando G. Vieira, M.D., corresponding author of the paper and director of research operations and in vivo operations at the ALS Therapy Development Institute. (prweb.com)