• peritonitis
  • It is suggested that solutions made with acetate may provide greater protection from peritonitis. (bmj.com)
  • There is a risk that patients who receive PD solutions that contain endotoxins may develop aseptic peritonitis. (drugs.com)
  • Patients and healthcare professionals should continue to look out for any symptoms that suggest the development of aseptic peritonitis (e.g. cloudy effluent seen in drain bag at the end of dialysis, abdominal pain, nausea, vomiting and possibly fever) and report any cases as soon as possible. (drugs.com)
  • No differences were found between the two solutions for residual renal function, technique survival, peritonitis rates or on additional end points including CRP and D/Pcreat and 4 hour UF rates during a PET. (nephrologynow.com)
  • My guess is that the potential benefit of biocompatible solutions would be demonstrated quickest on the recovery of a sick mesothelium such as patients with peritonitis where more rapid healing and recovery with a return to normal cell counts faster may be a better test of their potential benefit to our PD patients. (nephrologynow.com)
  • bicarbonate
  • Through dry storage and simple dissolution, even in a home, the invention enables a wider variety of solution constituents, including reduced acid content and the use of bicarbonate as a stable buffer component. (google.ca)
  • The bicarbonate-based solutions of the present invention are formulated and stored in at least two parts-an alkaline bicarbonate concentrate and an acidic concentrate. (google.com)
  • Upon mixing, although some variation in the pH of the mixed bicarbonate solution exists, the inventors have discovered that with the appropriate selection of the parameters of the concentrates, the pH of the mixed solution is always within an acceptable physiological range. (google.com)
  • 2. The multi-chamber container of claim 1 wherein the acidic concentrate has a pH effective to obtain, when the alkaline bicarbonate concentrate is mixed with the acidic concentrate, a mixed solution having a pH ranging from about 6.5 to 7.6. (google.com)
  • 7. The method of claim 6 wherein the step of adjusting the acidic concentrate is further defined by adjusting the acidic concentrate to a pH effective to obtain, when the alkaline bicarbonate concentrate is mixed with the acidic concentrate, a mixed solution having a pH ranging from about 6.5 to 7.6. (google.com)
  • The composition of the dialysis solution is also sometimes adjusted in terms of its sodium and potassium and bicarbonate levels. (wikipedia.org)
  • For another solute, bicarbonate, dialysis solution level is set at a slightly higher level than in normal blood, to encourage diffusion of bicarbonate into the blood, to act as a pH buffer to neutralize the metabolic acidosis that is often present in these patients. (wikipedia.org)
  • protein
  • Thus, a dialysis membrane with a 10K MWCO will generally retain greater than 90% of a protein having a molecular mass of at least 10kDa. (wikipedia.org)
  • Therefore, it is not practical to separate a 30kDa protein from a 10kDa protein using dialysis across a 20K rated dialysis membrane. (wikipedia.org)
  • icodextrin
  • The osmotic activity of icodextrin keeps the solution inside the peritoneum for three to four days, separating tissues and thus reducing adhesion between them when fibrin is formed after a surgery. (wikipedia.org)
  • When used for peritoneal dialysis, the icodextrin solution absorbs waste products from the blood, and is removed from the peritoneum after a few hours together with the waste. (wikipedia.org)
  • procedure
  • Although dialyzing a sample is relatively simple, a universal dialysis procedure for all applications cannot be provided due to the following variables: The sample volume The size of the molecules being separated The membrane used The geometry of the membrane, which affects the diffusion distance Additionally, the dialysis endpoint is somewhat subjective and application specific. (wikipedia.org)
  • treatments
  • dialysis treatments at home can be self-initiated and managed or done jointly with the assistance of a trained helper who is usually a family member. (wikipedia.org)
  • These include frequency (how many treatments per week), length of each treatment, and the blood and dialysis solution flow rates, as well as the size of the dialyzer. (wikipedia.org)
  • Pathology
  • From the Research Dialysis Center and Department of Pathology, Public Health Service Hospital, San Francisco, California 94118, U.S.A. (bmj.com)
  • molecules
  • In research laboratories, dialysis technique can also be used to separate molecules based on their size. (wikipedia.org)
  • In the context of life science research, the most common application of dialysis is for the removal of unwanted small molecules such as salts, reducing agents, or dyes from larger macromolecules such as proteins, DNA, or polysaccharides. (wikipedia.org)
  • Diffusion is the random, thermal movement of molecules in solution (Brownian motion) that leads to the net movement of molecules from an area of higher concentration to a lower concentration until equilibrium is reached. (wikipedia.org)
  • Dialysis can be used to either introduce or remove small molecules from a sample, because small molecules move freely across the membrane in both directions. (wikipedia.org)
  • Summary: Dialysis is the process used to change the matrix of molecules in a sample by differentiating molecules by the classification of size. (wikipedia.org)
  • Separating molecules in a solution by dialysis is a straightforward process. (wikipedia.org)
  • Blood
  • The present findings suggest that the use of low sodium PD solutions are safe and may lead to improvements in blood pressure control and maintenance of euvolemia. (ispdvancouver2018.org)
  • If you have diabetes and use this solution, the dose of your drugs which regulate the blood sugar level (e.g. insulin) should be evaluated on a regular basis. (drugs.com)
  • The higher the strength of glucose in the solution, the greater the amount of water that will be removed from the blood. (drugs.com)
  • peritoneum
  • Finally, in relatively healthy subjects I don't think that the detrimental effect of standard solutions on mesothelial cells and the immune system of the peritoneum found in the basic science lab will manifest rapidly enough to show up within a year, particularly on residual renal function. (nephrologynow.com)
  • Study
  • This study demonstrates the difficulty of demonstrating superiority in a small RCT where loss to follow up, wide confidence intervals, small numbers, and end points that lack true validation (and also that likely differ between dialysis units lowering generalizability) reduce the chances of finding a difference if one truly exists. (nephrologynow.com)
  • In this regard, to change practice, I would settle on a larger, more generalizable study that would assess the impact of these solutions on an important cardiovascular surrogate outcome such as positive changes in left ventricular geometry while recapitulating the safety profile of these solutions initially demonstrated. (ispdvancouver2018.org)
  • The current study is initiated in order to assess the impact of a PD solution containing L-carnitine on insulin sensitivity measured by a hyperinsulinemic euglycemic clamp. (clinicaltrials.gov)
  • process
  • http://www.kidney.org/atoz/content/vitamineral.cfm http://www.nwkidney.org/nutrition/vitamin.htm Kidney disease Kidney dialysis Mahan, K., Escott-Stump, S., and Raymond, J. Krause's Food and the Nutrition Care Process. (wikipedia.org)
  • Best practices for peritoneal dialysis state that before peritoneal dialysis should be implemented, the person's understanding of the process and support systems should be assessed, with education on how to care for the catheter and to address any gaps in understanding that may exist. (wikipedia.org)
  • production
  • LONDON, Jan. 21, 2011-The European Medicines Agency has been informed by Baxter that the problem of presence of endotoxins in peritoneal dialysis (PD) solutions has not been solved and that it cannot guarantee the production of endotoxin-free solutions from a production line at its Castlebar plant in Ireland in the short-term. (drugs.com)
  • The MWCO of a membrane is the result of the number and average size of the pores created during production of the dialysis membrane. (wikipedia.org)