• Deoxycytidine monophosphate (dCMP), also known as deoxycytidylic acid or deoxycytidylate in its conjugate acid and conjugate base forms, respectively, is a deoxynucleotide, and one of the four monomers that make up DNA. (wikipedia.org)
  • Vigabatrin had profound effects on many metabolites, increasing serum deoxycytidine monophosphate (dCMP) levels 52-fold. (bvsalud.org)
  • In a DNA double helix, it will base pair with deoxyguanosine monophosphate. (wikipedia.org)
  • During DNA synthesis, the two phosphates, alpha, and beta are removed in the reaction, leading to the formation of dGMP (deoxyguanosine monophosphate). (excedr.com)
  • The selective toxicity of 2-chloro-2΄-deoxy-β-D-adenosine towards certain normal and malignant lymphocyte and monocyte populations is based on the relative activities of deoxycytidine kinase and deoxynucleotidase. (nih.gov)
  • In cells with a high ratio of deoxycytidine kinase to deoxynucleotidase, it is phosphorylated by deoxycytidine kinase to 2-chloro-2΄-deoxy- β -D-adenosine monophosphate (2-CdAMP). (nih.gov)
  • It is postulated that cells with high deoxycytidine kinase and low deoxynucleotidase activities will be selectively killed by 2-chloro-2΄-deoxy- β -D-adenosine as toxic deoxynucleotides accumulate intracellularly. (nih.gov)
  • Clofarabine is sequentially metabolized intracellularly to the 5'-monophosphate metabolite by deoxycytidine kinase and mono- and di-phospho-kinases to the active 5'-triphosphate metabolite. (drugcentral.org)
  • Clofarabine has affinity for the activating phosphorylating enzyme, deoxycytidine kinase, equal to or greater than that of the natural substrate, deoxycytidine. (drugcentral.org)
  • deoxycytidine kinase [Source:HGNC S. (gsea-msigdb.org)
  • A strand of DNA is a polymer of nucleoside monophosphates linked by phosphodiester bonds. (rainis.pics)
  • 3′,4′-didehydro-3′-deoxycytidine diphosphate is provided as triethylammonium salt. (santiago-lab.com)
  • One to 30 microliters (microl) of styrene -oxide were reacted with 0.5 milligram calf thymus DNA, 2'- deoxyguanosine-3'-monophosphate (dGp), 2'-deoxyadenosine-3'- monophosphate (dAp), 2'-deoxycytidine-3'-monophosphate (dCp), or 2'- deoxythymidine-3'-monophosphate (dTp) in a Tris/hydrochloric-acid buffer, pH 7.5, at 37 degrees-C for about 15 hours. (cdc.gov)
  • Molecular Geometries and Electronic Structures of Adducts between 2'-Deoxycytidine-5'-monophosphate Acid and Hydroxyl Radical [J]. Acta Phys. (pku.edu.cn)
  • 1984) Kinetic interaction of 5-AZA-2'-deoxycytidine-5'-monophosphate and its 5'-triphosphate with deoxycytidylate deaminase. (jenabioscience.com)
  • 1983) Incorporation of 5-Aza-2'-deoxycytidine-5'-triphosphate into DNA. (jenabioscience.com)
  • 3′,4′-didehydro-3′-deoxycytidine duphosphate is a metabolite of 3′,4′-didehydro-3′-deoxycytidine triphosphate that has been proven to have antiviral properties. (santiago-lab.com)
  • Where can buy 2-Deoxycytidine 5-monophosphate sodium salt or if you want to know the price market of 2-Deoxy-5-cytidylic acid disodium salt? (nbinno.com)
  • Further biochemical characterization of SurE revealed that it has a broad substrate specificity and can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. (rhea-db.org)
  • YfbR was strictly specific to deoxyribonucleoside 5'-monophosphates, whereas YjjG showed narrow specificity to 5'-dTMP, 5'-dUMP, and 5'-UMP. (rhea-db.org)
  • China 2'-Deoxycytidine-5'-monophosphate disodium salt CAS:13085-50-2 manufacturer supplier producer and factory-NINGBO INNO PHARMCHEM CO.,LTD. (nbinno.com)
  • The amount of C5-hydroxymethyl-2′-deoxycytidine was higher in the stomachs of subjects without gastric cancer than in the nontumor and tumor portions of the stomach in gastric cancer patients. (biomedcentral.com)
  • 18. Production of cytidine 5'-monophosphate N-acetylneuraminic acid using recombinant Escherichia coli as a biocatalyst. (nih.gov)
  • Unlike the other fundamental nucleotides, dTMP is often referred to as thymidine monophosphate (abbreviated as TMP ) and the prefix deoxy - is dropped since it is a nucleotide component of DNA and not of RNA. (biologyonline.com)
  • N 6 -methyladenosine monophosphate (m6AMP) 40 ) are released to the nucleotide pools. (researchsquare.com)
  • In a DNA double helix, it will base pair with deoxyguanosine monophosphate. (wikipedia.org)
  • One to 30 microliters (microl) of styrene -oxide were reacted with 0.5 milligram calf thymus DNA, 2'- deoxyguanosine-3'-monophosphate (dGp), 2'-deoxyadenosine-3'- monophosphate (dAp), 2'-deoxycytidine-3'-monophosphate (dCp), or 2'- deoxythymidine-3'-monophosphate (dTp) in a Tris/hydrochloric-acid buffer, pH 7.5, at 37 degrees-C for about 15 hours. (cdc.gov)
  • Its monophosphate form, guanosine monophosphate (GMP), when salted out, acts as a flavoring agent that imparts an umami taste. (biologywise.com)
  • Depending on the number of phosphate groups attached to the sugar moiety, it may be called nucleoside monophosphate (if with only one phosphate group), nucleoside diphosphate (with two phosphate groups), or nucleoside triphosphate (when with three phosphate groups). (biologyonline.com)
  • In the first phosphorylation step, ara-G is converted to ara-G monophosphate (ara-GMP). (drugbank.com)
  • The major function of the pyrimidine nucleoside kinases is to maintain a cellular balance between the level of pyrimidine nucleosides and pyrimidine nucleoside monophosphates. (golifescience.com)
  • 7. UMP/CMPK is not the critical enzyme in the metabolism of pyrimidine ribonucleotide and activation of deoxycytidine analogs in human RKO cells. (nih.gov)
  • Deoxythymidine monophosphate (dTMP) is a nucleoside phosphate in being comprised of a deoxyribonucleoside and one phosphate group. (biologyonline.com)
  • Potential substrate, competitive inhibitor or regulator of enzymes that interact with 2'-deoxycytidine-5'- monophosphate. (gentaur.be)
  • The activatedhexanoic acid was dissolved in 1.5 ml of N,N-dimethylformamide (DMF), and 103 mg (0.45mmol) of 2'-deoxycytidine was added. (ambeed.com)