Deoxyadenosine is the DNA nucleoside A, which pairs with deoxythymidine (T) in double-stranded DNA. (wikipedia.org)
4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity. (adooq.com)
Adenosine and deoxyadenosine2
ADA degrades toxic adenosine and deoxyadenosine, which accumulate in the cells of patients. (lu.se)
Adenosine deaminase converts adenosine and deoxyadenosine to inosine and deoxyinosine, which are further broken down and excreted. (msdmanuals.com)
Adducts3
trans-4,5-Epoxy-2(E)-decenal reacted with 2'-deoxyadenosine to give 1,N(6)-etheno-2'-deoxyadenosine as well as other 2'-deoxyadenosine adducts. (nih.gov)
The LC-MS/MS (n = 4, p = 0.10) results were 6 ± 3 and 10 ± 6 fmol on the column or reaction results of 5 ± 2 and 9 ± 4 N-( deoxyadenosine-8-yl)-4-aminobiphenyl ( dA-ABP) adducts / 10 6 nucleotides in the oligo for the sense and anti-sense strands, respectively. (wmich.edu)
2015. Analysis of dibenzo[def,p]chrysene-deoxyadenosine adducts in wild-type and cytochrome P450 1b1 knockout mice using stable-isotope dilution UHPLC-MS/MS. . Mutat Res Genet Toxicol Environ Mutagen. (oregonstate.edu)
DATP1
A deoxyadenosine triphosphate (dATP) analogue for DNA labeling was synthesized with the 1-methylcyclopropene (1MCP) group at the 7-position of 7-deaza-2′-deoxyadenosine and applied for primer extension experiments. (dynamic-biosensors.com)
Cordycepin2
Deoxyribonucleotide Cordycepin (3′-deoxyadenosine) Severe combined immunodeficiency Griffiths, Anthony J. F. (wikipedia.org)
In these studies, we investigated whether platelet aggregation accelerates hematogenic metastasis of cancer cells in mice and the effect of cordycepin (3'-deoxyadenosine), a component of Cordyceps sinensis, on hematogenic metastasis accelerated by adenosine-5'-diphosphate (ADP). (nih.gov)
Deoxyguanosine2
Therefore, trans-4,5-epoxy-2(E)-decenal, a primary product of lipid peroxidation, is a precursor to the formation of 1,N(6)-etheno-2'-deoxyadenosine and 1,N(2)-etheno-2'-deoxyguanosine. (nih.gov)
One to 30 microliters (microl) of styrene -oxide were reacted with 0.5 milligram calf thymus DNA, 2'- deoxyguanosine-3'-monophosphate (dGp), 2'-deoxyadenosine-3'- monophosphate (dAp), 2'-deoxycytidine-3'-monophosphate (dCp), or 2'- deoxythymidine-3'-monophosphate (dTp) in a Tris/hydrochloric-acid buffer, pH 7.5, at 37 degrees-C for about 15 hours. (cdc.gov)
Enzyme2
We now report that the enzyme will accept 2′-deoxyadenosine in place of adenosine substrates, and structural evidence reveals a reorganisation in hydrogen bonding to accommodate this substrate series. (sinapse.ac.uk)
This enzyme breaks down molecules called adenosine and 2'-deoxyadenosine. (medlineplus.gov)
Triphosphate2
7-(Ferrocene-1-yl-ethynyl)-7-deaza-2′-deoxyadenosine triphosphate is a ferrocene-labeled analog of natural adenosine triphosphate. (santiago-lab.com)
Its conjugation at 7- position of 7-deaza-2′-deoxyadenosine triphosphate allows enzymatic incorporation of such adenosine triphosphate analog in primer extension reactions and PCR. (santiago-lab.com)
Antagonist1
Hartman, WR & Hentosh, P 2004, ' The Antileukemia Drug 2-Chloro-2′-deoxyadenosine: An Intrinsic Transcriptional Antagonist ', Molecular pharmacology , vol. 65, no. 1, pp. 227-234. (elsevierpure.com)
Fluorescent1
Novel rigid 8-biaryl-2′-deoxyadenosines with tuneable fluorescent properties can be accessed by an efficient sequential catalytic Pd0-coupling approach. (uea.ac.uk)
DAdo3
Deoxyadenosine (symbol dA or dAdo) is a deoxyribonucleoside. (wikipedia.org)
2′-Deoxyadenosine (2′-dAdo), a deoxyribonucleoside, may be used by some cells as an energy source under energy stress conditions and to affect cAMP levels. (sigmaaldrich.com)
During colonisation two secreted S. indica effectors synergistically produce the cell death inducer deoxyadenosine (dAdo). (biorxiv.org)
MeSH1
Deoxyadenosines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
Molecules2
The capture oligomers contain sequences complementary to specific regions of the target molecules as well as a string of deoxyadenosine residues. (cdc.gov)
This temperature reduction allows hybridization to occur between the deoxyadenosine region on the capture oligomer and the poly-deoxythymidine molecules that are covalently attached to the magnetic particles. (cdc.gov)
Link2
Link to all annotated objects annotated to 5'-deoxyadenosine deaminase activity. (planteome.org)
Link to all direct and indirect annotations to 5'-deoxyadenosine deaminase activity. (planteome.org)
Website1
This graph shows the total number of publications written about "Deoxyadenosines" by people in this website by year, and whether "Deoxyadenosines" was a major or minor topic of these publications. (umassmed.edu)
Activity1
A deoxyadenosine analog that displays strong antileukemic and immunosuppressive activity. (sigmaaldrich.com)