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  • found
  • In biology, histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes. (genenames.org)
  • sequences
  • TrEMBL was developed to handle the increasing amounts of data being generated by large-scale genomic projects, allowing scientists quicker access to new protein sequences before they were hand-curated and entered into SWISS-PROT. (eurekalert.org)
  • PIR is a joint effort between Georgetown University Medical Center and the National Biomedical Research Foundation in Washington, D.C. PIR was established in 1984 and resulted from the work of Dr. Margaret Dayhoff, Ph.D. Her Atlas of Protein Sequence and Structure, published from 1965-1978, was the first comprehensive collection of protein sequences. (eurekalert.org)
  • Automatic Quote will be generated only if sequences qualify for the Guaranteed service, as determined by our proprietary sequence analysis platform, failing which, our Technical Account Manager will contact you with a custom protein production quote. (genscript.com)
  • In this part of the exercise, we shall use Virtual Ribosome - a software that provides a series of functions to translate DNA to protein sequences. (dtu.dk)
  • Note, that the output shows both the DNA, and protein sequences as well as information on START and STOP codons. (dtu.dk)
  • The data may be either a list of database accession numbers, NCBI gi numbers, or sequences in FASTA format. (nih.gov)
  • No BLAST database contains all the sequences at NCBI. (nih.gov)
  • The search will be restricted to the sequences in the database that correspond to your subset. (nih.gov)
  • Protein the NIH protein database, a collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and Third Party Annotation, as well as records from SwissProt, PIR, PRF, and PDB Proteopedia the collaborative, 3D encyclopedia of proteins and other molecules. (wikipedia.org)
  • Also, includes protein pathways and gene sequences including other tools. (wikipedia.org)
  • molecules
  • The Cambridge Structural Database (CSD) is both a repository and a validated and curated resource for the three-dimensional structural data of molecules generally containing at least carbon and hydrogen, comprising a wide range of organic, metal-organic and organometallic molecules. (wikipedia.org)
  • Cell nuclei contain most of the cell's genetic material, organized as multiple long linear DNA molecules in complex with a large variety of proteins, such as histones, to form chromosomes. (wikipedia.org)
  • The pores cross both nuclear membranes, providing a channel through which larger molecules must be actively transported by carrier proteins while allowing free movement of small molecules and ions. (wikipedia.org)
  • Movement of large molecules such as proteins and RNA through the pores is required for both gene expression and the maintenance of chromosomes. (wikipedia.org)
  • Although the interior of the nucleus does not contain any membrane-bound sub compartments, its contents are not uniform, and a number of sub-nuclear bodies exist, made up of unique proteins, RNA molecules, and particular parts of the chromosomes. (wikipedia.org)
  • Although the exosomal protein composition varies with the cell and tissue of origin, most exosomes contain an evolutionarily-conserved common set of protein molecules. (wikipedia.org)
  • The protein content of a single exosome, given certain assumptions of protein size and configuration, and packing parameters, can be about 20,000 molecules. (wikipedia.org)
  • repository
  • BETHESDA, Md., Oct. 23, 2002 - Throwing its financial support behind the concept of a centralized repository for protein data, the National Human Genome Research Institute (NHGRI), in cooperation with five other institutes and centers at the National Institutes of Health (NIH), has awarded a three-year, $15-million grant to combine three of the world's current protein sequence databases into a single global resource. (eurekalert.org)
  • source of protein
  • The action is aimed at ensuring that researchers around the world will have free, unrestricted access to a comprehensive and non-redundant source of protein information, as well as creating a powerful tool for the study of human disease. (eurekalert.org)
  • molecular
  • It was maintained by Alexey G. Murzin and his colleagues in the Centre for Protein Engineering until its closure in 2010 and subsequently at the Laboratory of Molecular Biology in Cambridge, England. (wikipedia.org)
  • Proteins are inherently flexible and this database collects information on this subject for use in molecular research. (wikipedia.org)
  • Exosomes contain various molecular constituents of their cell of origin, including proteins and RNA. (wikipedia.org)
  • 2002
  • About the same time, centralizing protein database information became a goal at NHGRI, which with the National Institute of General Medical Sciences (NIGMS) and the National Library of Medicine (NLM), originally proposed the grant in 2001 as a single award of $4.5 million a year for each of three years, starting in fiscal year 2002 or 2003. (eurekalert.org)
  • The database was initially released in 2002. (wikipedia.org)
  • biology
  • The UniProt database will become a resource for all scientists to use, both to develop a better understanding of biology and to translate that basic science into clinical applications. (eurekalert.org)
  • Fraud
  • UAB began investigating claims of fraud in January 2007 after the validity of the proteins came into question. (wikipedia.org)
  • known
  • When known, the sub-nuclear compartment where the protein was found is reported. (programmableweb.com)
  • mDia1 (also known as Dia1, Drf1 for Diaphanous-related formin-1, Diaph1, KIAA4062, p140mDia, mKIAA4062, or D18Wsu154e) is a member of the protein family called the formins and is a Rho effector. (wikipedia.org)
  • Specifically, Murthy tried to pass some elements of the known protein 1TAQ as a new protein, 1CMW. (wikipedia.org)