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  • gene
  • Biobanks intend to focus on gene-environment association using genetic association studies models. (genomicsnetwork.ac.uk)
  • A curated genetic database focuses on genomes that have been completely sequenced and that are associated with an active research community to contribute and oversee gene-specific data. (ascopost.com)
  • An international database charting gene changes means families previously in the dark about their genetic risk can be offered definitive testing. (abc.net.au)
  • FINLAY MACRAE: Well we ve had breakthroughs in being able to assemble information that is otherwise in hidden corners around the world, either published or unpublished and directing them to a database that we have on the internet to enable an interpretation about the gene changes that s occurred in any one particular family that enables us to confidently say this change causes cancer across the family or it doesn't. (abc.net.au)
  • Because, you're probably aware, we're in the middle of a genetic revolution in terms of the capacity to find gene changes in your genome or my genome. (abc.net.au)
  • The purpose of this database is to provide information on BRCA1 and BRCA2 gene mutations and their impact on the risk of developing breast cancer, ovarian cancer and certain other cancers. (cnbc.com)
  • Please use the links below to access the LOVD database for the gene of interest. (euro-wabb.org)
  • In one study, 100% of patients with bipolar disorder indicated that they would probably take a genetic test to determine if he or she were carrying a gene associated with the disorder, if such a test existed. (wikipedia.org)
  • variants
  • The database now contains about 300 BRCA1 and BRCA2 variants, originally reported as VUS, which have now been clinically classified using an algorithm developed as a result of international collaborations. (cnbc.com)
  • genome
  • As genetic research has moved from Mendelian genetics to sequence maps to the study of human genetic variation at the level of the genome, there is an accompanying shift in emphasis in ethical framings of the issues - towards reciprocity, mutuality, solidarity, and citizenry. (genomicsnetwork.ac.uk)
  • The emerging market of direct-to-consumer genome sequencing services has brought new questions about both the medical efficacy and the ethical dilemmas associated with widespread knowledge of individual genetic information. (wikipedia.org)
  • At the same time technological advances also made it possible for wide sharing of information, so when data was collected, many scientists doing genetics work found that access to data from genome-wide scans collected for any one reason would actually be useful in many other types of genetic research. (wikipedia.org)
  • The Single Nucleotide Polymorphism Database (dbSNP) is a free public archive for genetic variation within and across different species developed and hosted by the National Center for Biotechnology Information (NCBI) in collaboration with the National Human Genome Research Institute (NHGRI). (wikipedia.org)
  • dbSNP accepts submissions for any organism from a wide variety of sources including individual research laboratories, collaborative polymorphism discovery efforts, large scale genome sequencing centers, other SNP databases (e.g. the SNP consortium, HapMap, etc.), and private businesses. (wikipedia.org)
  • The Condylostoma nuclear code (translation table 28) is a genetic code used by the nuclear genome of the heterotrich ciliate Condylostoma magnum. (wikipedia.org)
  • clinical
  • Many public databases are not curated to be useful for clinical use," points out Kusukawa. (cnbc.com)
  • To achieve this goal, Cordova provides an interface to review and manually or computationally curate genetic variation data as well as share it for clinical diagnostics and the advancement of research. (plu.mx)
  • genomics
  • The genomics institutes, including the Robert S. Boas Center for Genomics and Human Genetics at the Feinstein Institute for Medical Research and The Children's Hospital of Philadelphia are the first to donate, in total, more than 6,000 control samples to the database. (technologynetworks.com)
  • This database will benefit the research community at large by providing investigators with an extensive set of control samples to validate their genetic studies," said Hakon Hakonarson, M.D., Ph.D., Director of the Center for Applied Genomics at The Children's Hospital of Philadelphia, who supplied 4,000 control samples to the database. (technologynetworks.com)
  • linkage
  • Specifically designed to facilitate large-scale (multi-center) genetic linkage or association studies, GeneLink securely and efficiently handles large amounts of data and provides additional features to facilitate data analysis by existing software packages and quality control. (biomedcentral.com)
  • Genetic Linkage studies attempt to find a correlation between the diagnosis and inheritance of certain alleles within families who have two or more ill relatives. (wikipedia.org)
  • An analysis of a linkage study uses a wide chromosomal region, whereas a genetic association study endeavors to identify a specific DNA polymorphism, which can be a deletion, inversion, or repletion of a sequence. (wikipedia.org)
  • Whereas
  • Whereas before data usually stayed in one laboratory, now scientists began to store large amounts of genetic data in single places for community use and sharing. (wikipedia.org)
  • Genotype
  • SQL database queries are used to analyze the genetic data, including locating probable significant associations between genotype and phenotype data. (patents.com)
  • populations
  • Out of all the national/ethnic mutation databases (NEMDBs), FINDbase has the most content and since all the entries are collected from various populations worldwide, it is seen as a great resource for population-specific information. (wikipedia.org)
  • MeSH
  • Databases, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uams.edu)
  • conduct
  • 5) to conduct a small typological or genetic linguistic study as a showcase of the utility of the database and user interface. (gu.se)
  • research
  • Genetic databases provide new dimensions and new niches to examine the ethics of different traditions of research and to undertake a comparative analysis in different societies of the world and its implications on global health. (genomicsnetwork.ac.uk)
  • Ethical Issues of Human Genetic Databases: A Challenge to Classical Health Research Ethics? (cambridge.org)
  • In a continuation of a 2014 conference that explored regulatory considerations and strategies for next-generation sequencing, the Friends of Cancer Research, with support from Alexandria Real Estate Equities, Inc, Pasadena, California, met to discuss the issues and problems of coordinating drug and diagnostic development, specifically the use of curated databases. (ascopost.com)
  • Over the last few years, linguists and computaional linguists have started looking into the possibilities of using multilingual corpora (mainly parallel corpora) for typological and genetic linguistic research. (gu.se)
  • The Act on Health Sector Database, also known as Act on Health Sector Database, No. 139/1998, the Health Sector Database Act and in media by other colloquial names, was a 1998 act of the Icelandic Parliament which allowed the Icelandic government to grant a license to a private company for the creation of a national biological database to store health information which could be used for research. (wikipedia.org)
  • Genograms are now used by various groups of people in a variety of fields such as medicine, psychiatry, psychology, social work, genetic research, education, and many more. (wikipedia.org)
  • data
  • The rapid developments in molecular diagnostics and ever expanding wealth of biological data have provoked issues concerning the deciphering, storing, validating, annotating and integrating of information in different kinds of genomic databases. (genomicsnetwork.ac.uk)
  • From this database one can obtain patient based data with respect to patient's Geographical location, Age, Sex, and Ethnic Group. (wikipedia.org)
  • Given the considerable number of genotypes requiring analysis, it was obvious that we needed to develop a database management system that could handle such large quantities of data, as well as address data management issues unique to complex trait genetic analysis. (biomedcentral.com)
  • mutation
  • JENNY JENKINS: We were a very fortunate family in that we were one of the first to be able to make use of genetic testing and be provided with a definite answer about carrying this mutation. (abc.net.au)
  • study
  • In order to address these challenges, which are inherent in any large, collaborative genotyping study, we have developed a robust, easy-to-use database system named GeneLink. (biomedcentral.com)
  • contains
  • Its goal is to act as a single database that contains all identified genetic variation, which can be used to investigate a wide variety of genetically based natural phenomenon. (wikipedia.org)
  • Goal
  • He started the Million Veterans Program which has a goal of collecting genetic information from veterans and linking that information to the VA electronic health record. (wikipedia.org)
  • project
  • The overall objective of this project was to explore the ethical, regulatory and governance issues arising out of the use of genetic databases. (genomicsnetwork.ac.uk)
  • Given the broad reach of the four strands associated with the Databases project, the methodology involved an array of techniques. (genomicsnetwork.ac.uk)
  • The establishment of a national database for all Icelandic citizens raised discussion about the nature of the informed consent process for the project. (wikipedia.org)
  • Analysis
  • We estimate that this database will provide at least a 50 percent cost savings, in addition to nearly halving the time necessary for processing samples," said Carsten Rosenow, Ph.D., DNA Analysis Senior Marketing Manager at Illumina. (technologynetworks.com)
  • studies
  • To minimize the difficulties inherent in complex trait studies, we have developed GeneLink, a Web-accessible, password-protected Sybase database. (biomedcentral.com)
  • human
  • SHARe represents a major milestone in moving toward an era of personalized health care -- a future in which the ways we prevent, diagnose and treat health problems are tailored to an individual's genetic makeup," U.S. Health and Human Services Secretary Mike Leavitt said in a prepared statement. (bio-medicine.org)
  • individual
  • The empirical work showed that the requirement for individual informed consent does not address wider concerns over the type of society genetic applications could bring about, the commercialization and commodification of information and the privatization of public goods. (genomicsnetwork.ac.uk)
  • help
  • RACHAEL BROWN: This consumer representative for the Cancer Council says the global database will now help countless families make better informed decisions. (abc.net.au)
  • Some genetic tests of born children might help finding the right treatment. (wikipedia.org)
  • diversity
  • Presently gazelles are suffering not only from poor pasture conditions, but also from problems associated with small populations such as lack of genetic diversity in the population, which makes them less resistant to diseases. (wikipedia.org)
  • The disparity in molecular sequences is very high between the three main lineages of cycads, implying that genetic diversity in the clade was once high. (wikipedia.org)
  • Disease
  • Brendan Fraser and Keri Russell play John Crowley and his wife, Aileen, a Portland couple with two of their three children suffering from Pompe disease, a genetic anomaly that typically kills most before a child's tenth birthday. (wikipedia.org)
  • gene
  • The simpliest way to perform gene annotation relies on homology based search tools, like BLAST, to search for homologous genes in specific databases, the resulting information is then used to annotate genes and genomes. (wikipedia.org)
  • Here is an alphabetical listing of on-going projects relevant to genome annotation: Encyclopedia of DNA elements (ENCODE) Entrez Gene Ensembl GENCODE Gene Ontology Consortium GeneRIF RefSeq Uniprot Vertebrate and Genome Annotation Project (Vega) At Wikipedia, genome annotation has started to become automated under the auspices of the Gene Wiki portal which operates a bot that harvests gene data from research databases and creates gene stubs on that basis. (wikipedia.org)
  • protein
  • The key of our method is the systematic purification of several tagged components of the protein complex in multiple genetic deletion strains, which serve to compromise the integrity of the complex. (embopress.org)
  • Phage display is a laboratory technique for the study of protein-protein, protein-peptide, and protein-DNA interactions that uses bacteriophages (viruses that infect bacteria) to connect proteins with the genetic information that encodes them. (wikipedia.org)
  • biological
  • In the 1980s, HMMs were emerging as a useful tool in the analysis of biological systems and information, and in particular genetic information. (wikipedia.org)
  • Identifying the locations of genes and other genetic control elements is often described as defining the biological "parts list" for the assembly and normal operation of an organism. (wikipedia.org)
  • Genome annotation is an active area of investigation and involves a number of different organizations in the life science community which publish the results of their efforts in publicly available biological databases accessible via the web and other electronic means. (wikipedia.org)
  • data
  • In November 1993, the National Forum on Breast Cancer issued a recommendation to develop a policy with respect to genetic screening and to consider whether there should be legislated protection for women in such areas as privacy, insurance and misuse of data. (docplayer.net)
  • Some databases use genome context information, similarity scores, experimental data, and integrations of other resources to provide genome annotations through their Subsystems approach. (wikipedia.org)
  • recent
  • A recent review of the KIDS inpatient database for the year 2009 showed acute mastoiditis to be the most common complication of acute otitis media in children admitted with a diagnosis of otitis media. (neurologyadvisor.com)