Naphthalene-1-sulfonylChlorideSynthesisExtinction coefficientIonsCarboxylicAbsorptionOrganic acidsCleavageDerivativeEmissionUltravioletDRUGSLife SciencesConditionsGroupAnalysisSpecificClassesHumanFoundResultsLowerDimethylaminoAmino acidDerivativesProteinsFluorescentSpectraIsotopesLigandsAffinityConcentrationGroupDeterminationRetentionCompositionsBiologicalOrganicDISEASESAnalysisWaterShownSiteIdentificationTables
Naphthalene-1-sulfonyl2
- Dansyl chloride or 5-(dimethylamino)naphthalene-1-sulfonyl chloride is a reagent that reacts with primary amino groups in both aliphatic and aromatic amines to produce stable blue- or blue-green-fluorescent sulfonamide adducts. (wikipedia.org)
- This mouse IgG2b, κ isotype control is a monoclonal antibody, clone 27-35, that is specific for the dansyl (5-[dimethylamino] naphthalene-1-sulfonyl) hapten. (bdbiosciences.com)
Chloride5
- Dansyl chloride may also be denoted DNSC. (wikipedia.org)
- Dansyl chloride is unstable in dimethyl sulfoxide, which should never be used to prepare solutions of the reagent. (wikipedia.org)
- Dansyl chloride is one of the simplest sulfonamide derivatives, so it commonly serves as a starting reagent for the production of other derivatives. (wikipedia.org)
- Exotic derivatives may have very different extinction coefficients, but others, such as dansyl amide, are similar to dansyl chloride in absorption and fluorescence characteristics. (wikipedia.org)
- But even for dansyl chloride, there are a variety of extinction coefficient values that have been reported. (wikipedia.org)
Synthesis2
- Synthesis of compound librariesto improve the biological activities or oral bio-availability. (shinepeptide.com)
- In addition to the synthesis of small molecules by classical chemistry, he succeeded by developing solid-phase syntheses of C18-steroid (estrane) derivatives as well as C19-steroid (androstane) derivatives that enabled the generation of model libraries of targeted therapeutic compounds. (ulaval.ca)
Extinction coefficient2
- The extinction coefficient of dansyl derivatives are important for measuring their concentration in solution. (wikipedia.org)
- The substrate is highly specific to FTase and is not recognized by geranylgeranyl transferse type I (GGTase I). Concentrations of stock solutions of Dns-GCVLS can be calculated from the extinction coefficient of the dansyl moiety (e340 = 4250 M-1cm-1 in 20 mM Tris-HCl, pH 7.5, 10 mM EDTA). (cymitquimica.com)
Ions1
- 5 has been isolated as two not yet described conformational isomers) featuring two directly lower rim attached dansyl moieties besides other lower or upper rim site substituents have been synthesized and investigated with reference to their fluorescence properties including potential sensing capability for metal ions. (lincoln.ac.uk)
Carboxylic2
- There are numerous classes of low-molecular-weight compounds, and they are categorized based on their functional groups, including amine, thiol, and carboxylic groups. (encyclopedia.pub)
- For example, the tricarboxylic acid (TCA) cycle, which is the principal energy-producing process in cells, involves nine carboxylic acid compounds. (encyclopedia.pub)
Absorption4
- 1963) Tables of Spectrophotometric Absorption Data of Compounds Used for the Colorimetric Determination of Elements. (photochemcad.com)
- Hirayama, K. (1967) Handbook of Ultraviolet and Visible Absorption Spectra of Organic Compounds. (photochemcad.com)
- The ultraviolet absorption properties of these compounds are determined by the methylenedioxyphenyl ring, which shows major absorption bands in the 285- and 235-nm range. (erowid.org)
- Compounds of the HMDA series have UV absorption properties similar to the MDAs because both series contain the same 3,4-methylenedioxyphenyl chromophore. (erowid.org)
Organic acids2
- Carboxyl-bearing low-molecular-weight compounds such as keto acids, fatty acids, and other organic acids are involved in a myriad of metabolic pathways owing to their high polarity and solubility in biological fluids. (encyclopedia.pub)
- LAB that are usually designated as generally recognized as safe (GRAS) status in foods can also exert a biopreservative effect against other microorganisms as a result of competition for nutrients and/or of the production of antagonistic compounds such as organic acids, diacetyl, acetoin, hydrogen peroxide, antibiotics, and bacteriocins (Schillinger et al. (e-fas.org)
Cleavage1
- Thus, he developed a diethylsilylacetylenic linker that produces more stable compounds and a sulfamate linker that produces two classes (phenol and sulfamate) of relevant steroidal or nonsteroidal compounds according to cleavage conditions. (ulaval.ca)
Derivative2
- Likewise, a similar derivative, dansyl amide is known as DNSA. (wikipedia.org)
- The compounds are not completely resolved by gas chromatography on an HP-1 phase, and the separation is complicated by extensive thermal degradation of the N-hydroxy derivative (MDP-2-OHB). (erowid.org)
Emission1
- Due to farnesylation of the cysteine thiol group the dansyl group is placed from a polar to a non-polar molecular environment which is accompanied by an enhancement of fluorescence and a shift to a lower wavelength emission maximum of the dansyl group. (cymitquimica.com)
Ultraviolet1
- Friedel, R. A. and M. Orchin (1951) Ultraviolet Spectra of Aromatic Compounds. (photochemcad.com)
DRUGS1
- The analytical properties of these compounds are compared with the structurally similar 3,4-methylenedioxyamphetamine (MDA) derivatives, a popular series of drugs of abuse. (erowid.org)
Life Sciences1
- Quantification of low-molecular-weight compounds, as exemplified by metabolomics studies, has become increasingly important in the life sciences. (encyclopedia.pub)
Conditions1
- Therefore, the quantification of such compounds provides useful information pertaining to diagnosis, pathological conditions, and disease mechanisms, spurring the development of numerous analytical methods for this purpose. (encyclopedia.pub)
Group1
- The pentapeptide is based on the C-terminal region of H-Ras with a dansyl group attached to the N-terminus. (cymitquimica.com)
Analysis1
- Investigation of Solvent-Free MALDI-TOFMS Sample Preparation Methods for the Analysis of Organometallic and Coordination Compounds by: Anthony Brenton, et al. (swan.ac.uk)
Specific1
- The mass spectra for these compounds provide specific structural information for the identification of these compounds. (erowid.org)
Classes1
- The model was validated on 110 compounds representing 4 chemical classes. (fieldofscience.com)
Human1
- The dansyl (DNS) hapten is not expressed on human cells or human cell lines. (bdbiosciences.com)
Found3
- Except for the nitro substituted compound 7, which showed a moderate fluorescence quenching on the addition of Hg2+ in acetonitrile, the calixarenes 2-6 were found to selectively recognize Cu2+ in the 10(-6) mol L(-1) concentration range detectable by the nearly total quenching of their intrinsic fluorescence. (lincoln.ac.uk)
- Various disease areas such as cancer, myeloid leukemia, heart disease, liver disease, and lifestyle diseases (obesity and diabetes) were found to be related to certain metabolic pathways and changes in the concentrations of the compounds involved in those pathways. (encyclopedia.pub)
- The five LAB strains identified as Pediococcus acidilactici MCL11, Leuconostoc mesenteroides MCL12, Enterococcus faecium MCL13, Lactobacillus sakei MCL14, and Lactobacillus acidophilus MCL15 were found to produce an antibacterial compound with inhibitory activity against the tested histamine-producing bacteria. (e-fas.org)
Results1
- Site Selective Investigation of Surfactant Compounds Using Excited State Proton Transfer of Pyranine" is an authentic record of the results obtained from the research work carried out under my supervision in the Department of Chemistry, Indian Institute of Technology Guwahati, Assam, India, was carried out. (azpdf.net)
Lower2
- Calix[4]arenes featuring a direct lower rim attachment of dansyl groups. (lincoln.ac.uk)
- In this paper we also present the first crystal structures of dansylated calixarenes having the dansyl groups directly attached to the lower rim site. (lincoln.ac.uk)
Dimethylamino1
- We have now determined the relative HSA-binding affinities for a group of LC-PCBs and their hydroxylated and sulfated derivatives by selective displacement of the fluorescent probes 5-dimethylamino-1-naphthalenesulfonamide and dansyl-l-proline from the two major drug-binding sites on HSA (previously designated as Site I and Site II). (nih.gov)
Amino acid1
- These resins may be used directly for adsorpotion of compounds having an affinity for the particular amino acid immobilized, or they can serve as functionalised linkers and allow covalent attachment through their free carboxyl terminus to a ligand containing a free primary amine. (sigmaaldrich.com)
Derivatives1
- The extinction coefficient of dansyl derivatives are important for measuring their concentration in solution. (wikipedia.org)
Proteins1
- Each is designed for highly specific and efficient purification of proteins and related compounds. (sigmaaldrich.com)
Fluorescent1
- A macrocyclic and a linear trimer of a facially amphiphilic cholate building block were labeled with a fluorescent dansyl group. (bepress.com)
Spectra4
- Friedel, R. A. and M. Orchin (1951) Ultraviolet Spectra of Aromatic Compounds. (photochemcad.com)
- Hirayama, K. (1967) Handbook of Ultraviolet and Visible Absorption Spectra of Organic Compounds. (photochemcad.com)
- The Chenomx NMR Suite Professional v. 6.0 is used for identifying and quantifying individual compounds based on the respective signature spectra compiled in libraries. (metabolomicscentre.ca)
- Employing the unique technology, called "targeted" metabolite profiling, ChenoMX suite currently offers identification and quantification of more than 300 compounds from 1H NMR spectra of complex analyte mixtures. (metabolomicscentre.ca)
Isotopes3
- When samples are labeled by metabolically uptaking stable isotopes (metabolic isotope labeling), describe isotope-labeled compounds in the "isotope_labeled_compound" attributes of BioSample records. (nig.ac.jp)
- In the SDRF rows correspond to the samples, describe the compounds and isotopes in the Characteristics columns. (nig.ac.jp)
- When samples are chemically labeled by isotopes (chemical isotope labeling), describe isotopes in the SDRF Label column and isotope-labeled compounds in the Comment[isotope_labeled_compound] column. (nig.ac.jp)
Ligands1
- We offer appropriately selective ligands on beaded and porous matrices for binding target compounds, which are then recovered under mild conditions. (sigmaaldrich.com)
Affinity1
- Affinity chromatography is the preferred method of bioselective adsorption and subsequent recovery of a compound from an immobilized ligand. (sigmaaldrich.com)
Concentration1
- Concentration-dependent emission wavelength and intensity revealed a higher concentration of water for the cyclic compound. (bepress.com)
Group5
- Compounds that contain a 1-dimethylaminonaphthalene-5-sulfonyl group. (nih.gov)
- A group of compounds that contain the structure SO2NH2. (lookformedical.com)
- The free ends, the bottom, and the random of brushes were labeled with dansyl group. (elsevierpure.com)
- and C signifies the residue of compound comprising at least one amido group, one primary amino group, and one secondary amino group, wherein C is linked to B via a nitrogen atom of an amino group, wherein said compound is a poly(amidoamine). (justia.com)
- Photoaffinity labeling compound for labeling antibodies with aryl nitrene as the reactive group. (soltecventures.com)
Determination1
- We focused on the determination of biologically active compounds that determine wine quality and safety. (ung.si)
Retention2
- One of the advantages of GC-MS is that the identification is based on both a retention time and a mass spectrum (a compounds' specific fragmentation pattern). (metabolomicscentre.ca)
- Many compounds are easily biotinylated with retention of biological activity, allowing for a broad range of separation applications. (sigmaaldrich.com)
Compositions1
- The compositions include one or more polymeric acid compounds and/or polymeric acid anhydride compounds in addition to one or more active agents for chemically treating the hair. (justia.com)
Biological1
- Carboxylic acid containing compounds (R-COOH) are involved in a large number of biological processes and they are relevant for several pathological processes such as neurodegeneration or cancer. (biomed.news)
Organic2
- DMS, UV Atlas of Organic Compounds. (photochemcad.com)
- CRC Atlas of Spectral Data and Physical Constants for Organic Compounds. (photochemcad.com)
DISEASES1
- PMID- 5157720 TI - 1-Hydroxy-3-amino-pyrrolidone-2(HA-966): a new GABA-like compound, with potential use in extrapyramidal diseases. (nih.gov)
Analysis1
- The combination of LC-based hydrophilic interaction liquid chromatography (HILIC) and a hybrid quadrupole-time of flight (Q-ToF) mass spectrometer allows the comprehensive analysis of small polar metabolites including sugars, phosphorylated compounds, purines and pyrimidines, nucleotides, nucleosides, acylcarnitines, carboxylic acids, hydrophilic vitamins and amino acids. (biomed.news)
Water2
- Both compounds were shown by the red-edge excitation shift (REES) to be located near the membrane/water interface at low concentrations, but the cyclic trimer was better able to migrate into the hydrophobic core of the membrane than the linear trimer. (bepress.com)
- Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. (bdbiosciences.com)
Shown1
- A) Compound 1 shown as a green spheres model binds in the lipid binding site in the C-terminal domain of SPHK1, shown in red. (nih.gov)
Site1
- En poursuivant votre navigation sur ce site, vous acceptez l'utilisation de ces cookies. (sensagent.com)
Identification1
- Compounds produce reproducible fragmentation patterns when ionized by a fixed electron voltage (usually 70eV) making the technique particularly valuable for identification and quantification for small molecules as it means it is instrument independent and allows databases to be created and shared between users. (metabolomicscentre.ca)
Tables1
- In the following tables the similarities of the query compound to the original X-Ray compunds are presented. (althotas.com)