• The genomic DNA is provided at ≥10 ng/μl concentration in TE buffer pH 8.0.It is recommended to avoid freeze thaw cycles of this product. (sigmaaldrich.com)
  • Patients with ecDNA-containing tumours have significantly shorter survival, even compared to other forms of genomic focal amplification 3 . (nature.com)
  • DNA microarrays can be used to detect DNA (as in comparative genomic hybridization), or detect RNA (most commonly as cDNA after reverse transcription) that may or may not be translated into proteins. (wikipedia.org)
  • Blood samples have traditionally been considered the gold standard DNA source for genomic analysis, but obtaining blood samples is a painful, invasive, and costly procedure that must be performed by qualified personnel. (isohelix.com)
  • DNA synthesis can be impeded by collisions between the DNA replication machinery and co-transcriptional R-loops leading to a major source of genomic instability in cancer cells. (leica-microsystems.com)
  • Karlyn Grafals Nieves and Benjamin W. van Ee "DNA Barcoding of Adiantum (Pteridaceae: Vittarioideae) in Puerto Rico," Caribbean Journal of Science 51(2), 287-313, (20 December 2021). (bioone.org)
  • In the knot structure, C letters on the same strand of DNA bind to each other -- so this is very different from a double helix, where 'letters' on opposite strands recognise each other, and where Cs bind to Gs [guanines]. (sciencedaily.com)
  • Taq polymerase catalyzes oligonucleotide primer-driven, DNA template dependent incorporation of dNTPs into complimentary DNA strands. (sigmaaldrich.com)
  • The core principle behind microarrays is hybridization between two DNA strands, the property of complementary nucleic acid sequences to specifically pair with each other by forming hydrogen bonds between complementary nucleotide base pairs. (wikipedia.org)
  • In the knot structure, C letters on the same strand of DNA bind to each other - so this is very different from a double helix, where 'letters' on opposite strands recognise each other, and where Cs bind to Gs [guanines]', said co-author Associate Professor Marcel Dinger, Head,of the Kinghorn Centre for Clinical Genomics at Garvan. (meba.ro)
  • Crucially, the antibody fragment didn't detect DNA in helical form, nor did it recognise 'G-quadruplex structures' (a structurally similar four-stranded DNA arrangement). (sciencedaily.com)
  • This antibody fragment did not recognise DNA in helical form and it did not recognise 'G-quadruplex structures' - which are structurally similar to four-stranded DNA arrangement. (meba.ro)
  • Their research, recently published in the journal Nature Communications , shows how they've detected fast-forming mutations--called 'DNA (6-4) photo adducts' by scientists. (news-medical.net)
  • Photo adducts are lesions formed by a light-induced reaction in cellular DNA, which can lead to skin cancers. (news-medical.net)
  • Aristolochic acid IVa forms DNA adducts in vitro but is non-genotoxic in vivo. (bvsalud.org)
  • Aristolochic acids (AAs) are a family of natural compounds with AA I and AA II being known carcinogens , whose bioactivation causes DNA adducts formation. (bvsalud.org)
  • AA IVa reacted with 2'-deoxyadenosine (dA) and 2'- deoxyguanosine (dG) to form three dA and five dG adducts as identified by high-resolution mass spectrometry , among which two dA and three dG adducts were detected in reactions of AA IVa with calf thymus DNA (CT DNA ). (bvsalud.org)
  • However, no DNA adducts were detected in the kidney , liver , and forestomach of orally dosed mice at 40 mg/kg/day for 2 days, and bone marrow micronucleus assay also yielded negative results . (bvsalud.org)
  • The competitive reaction of AA I and AA IVa with CT DNA , with adducts levels varying with pH of reaction revealed that AA IVa was significantly less reactive than AA I, probably by hydroxyl deprotonation of AA IVa, which was explained by theoretical calculations for reaction barriers, energy levels of the molecular orbits , and charges at the reaction sites. (bvsalud.org)
  • In brief, although it could form DNA adducts in vitro , AA IVa was non-genotoxic in vivo, which was attributed to its low reactivity and biotransformation into an easily excreted metabolite rather than bioactivation. (bvsalud.org)
  • Detection of styrene oxide-DNA adducts by 32P-postlabeling. (cdc.gov)
  • The formation of DNA adducts by styrene -7,8-oxide (96093) ( styrene - oxide) was studied in-vitro. (cdc.gov)
  • Five styrene -oxide/DNA adducts were detected. (cdc.gov)
  • The overall extent of DNA modification by 5microl styrene -oxide was approximately 4.4x10(-4) adducts per nucleotide. (cdc.gov)
  • Styrene -oxide formed five adducts with dGp and two with dAp. (cdc.gov)
  • Thin layer chromatography of the adducts on polyethyleneimine plates showed that the styrene -oxide/DNA adducts were similar to the corresponding DNA adducts. (cdc.gov)
  • The cells were examined for DNA adducts as before. (cdc.gov)
  • the overall extent of DNA modification by styrene -oxide amounted to 19.5x10(-6) adducts/nucleotide. (cdc.gov)
  • The adducts seem to be similar to those formed with calf thymus DNA. (cdc.gov)
  • The P-32 postlabeling technique can be used to detect formation of styrene - oxide/DNA adducts. (cdc.gov)
  • Predicting the conformation of DNA from its primary sequence, although desirable, is a challenging problem owing to the polymorphic nature of DNA. (lu.se)
  • Therefore, the design of aqueous solvents that are able to stabilize and maintain DNA conformation is a challenging issue. (spiedigitallibrary.org)
  • We have investigated the thermal stability of DNA in 1-butyl-3-methylimidazolium aqueous solutions by synchrotron-based UV Resonance Raman (UVRR) spectroscopy with the aim to clarify the role played by concentration of IL in stabilizing the DNA natural conformation. (spiedigitallibrary.org)
  • Isohelix buccal swabs are designed with a unique matrix to increase yields of high quality DNA samples. (isohelix.com)
  • They also showed that i-motifs appear in some promoter regions (areas of DNA that control whether genes are switched on or off) and in telomeres, 'end sections' of chromosomes that are important in the aging process. (sciencedaily.com)
  • Over time, they've come to appreciate that the way DNA is folded up within the nucleus of cells is more than just a convenient storage method-it's a way to control which genes are expressed. (thebrf.org)
  • So, as they continue to hunt for disease-linked genes they are also working to understand how the 3D structure of folded DNA may also contribute to brain disease. (thebrf.org)
  • The team's preliminary data suggested that such structural changes in DNA may cause neurodevelopmental disorders by altering the activity of important genes. (thebrf.org)
  • Scientists use DNA microarrays to measure the expression levels of large numbers of genes simultaneously or to genotype multiple regions of a genome. (wikipedia.org)
  • Over the past decades, empirical discussions have been proposed to modify the genes in the DNA. (nature.com)
  • Complexes formed between DNA and cationic polymers are attracting increasing attention as novel synthetic vectors for delivery of genes. (ox.ac.uk)
  • Nutrigenetic DNA tests examine the genes and variants of these genes involved in specific nutrients and their metabolism. (hindustantimes.com)
  • They also appear more in promoter regions, which are areas of DNA that control whether genes are switched on or off. (meba.ro)
  • The chromosomes and genes have a special code called DNA. (cdc.gov)
  • All forms of recombinant DNA technology, including modification of the genes of plants and animals, raise extremely important safety issues and need careful monitoring and control. (who.int)
  • Taq DNA Polymerase is a thermostable enzyme derived from the thermophilic bacterium Thermus aquaticus . (sigmaaldrich.com)
  • Each lot of Taq DNA Polymerase is tested for PCR amplification and double-stranded sequencing. (sigmaaldrich.com)
  • Taq DNA polymerase comes with the choice of an optimized 10× reaction buffer including MgCl 2 (D1806) or a 10× reaction buffer without MgCl 2 plus a separate tube of MgCl 2 for titration (D4545). (sigmaaldrich.com)
  • Before this image is being captured, DNA computing involves parallel overlap assembly (POA) and polymerase chain reaction (PCR) that is the main of this computing algorithm. (researchgate.net)
  • Here, oh 8 dGTP and DNA polymerase were used in two complementary bacteriophage plaque color assays to examine the mutagenic specificity of oh 8 Gua in vivo. (psu.edu)
  • We used the chloroplast markers trnL-F and rbcL to construct a DNA barcode sequence library of Adiantum (Pteridaceae) from Puerto Rico. (bioone.org)
  • Each DNA spot contains picomoles (10−12 moles) of a specific DNA sequence, known as probes (or reporters or oligos). (wikipedia.org)
  • This idea will be presented to stop the cancerous cell's protein synthesis and modifying DNA sequence and genetic manipulation of the cell. (nature.com)
  • Information regarding the DNA sequence during the computing process as well as the computing output can be extracted at the same time using the simulation software. (researchgate.net)
  • One to 30 microliters (microl) of styrene -oxide were reacted with 0.5 milligram calf thymus DNA, 2'- deoxyguanosine-3'-monophosphate (dGp), 2'-deoxyadenosine-3'- monophosphate (dAp), 2'-deoxycytidine-3'-monophosphate (dCp), or 2'- deoxythymidine-3'-monophosphate (dTp) in a Tris/hydrochloric-acid buffer, pH 7.5, at 37 degrees-C for about 15 hours. (cdc.gov)
  • The GFX-03 Xtra uses 1ml of our concentrated buffer to stabilize 3ml of saliva DNA/RNA for when maximum quantity is required. (isohelix.com)
  • Saliva collection kits can stabilize DNA at room temperature for over five years, avoiding the high cost and logistical challenges of cold chain transport. (isohelix.com)
  • In a follow up study {ii}, GeneFix saliva stability samples that had been stored for up to 48 months at room temperature were tested, and no change in the proportion of bacterial DNA in samples over the stability period was found, demonstrating the GeneFix collectors fully stabilize saliva samples, preserve DNA and prevent microbial growth. (isohelix.com)
  • Deoxyribonucleic acid, more commonly known as DNA, is an evolved molecule that contains the genetic code of organisms. (nature.com)
  • The Full Form of DNA is Deoxyribonucleic Acid. (thefullformdictionary.com)
  • Although Deoxyribonucleic acid (DNA) is considered substantially stable in aqueous solution, slow hydrolysis can damage its double-helix structure and cause denaturation when it is stored for several months. (spiedigitallibrary.org)
  • They discovered that the children had changes in the 3-dimensional structure of their DNA that altered gene activity without changing the gene's themselves. (thebrf.org)
  • She planned to systematically use state-of-the-art CRISPRCas9 technology to make cuts in noncoding DNA that change the 3D structure of the DNA and then use RNA sequencing to document how each change alters gene expression in brain cells grown in the laboratory from human stem cells. (thebrf.org)
  • The study will be the first to directly model structural rearrangements of the genome in human brain tissue to determine whether disrupting noncoding segments of DNA responsible for proper 3D folding can be as damaging as direct gene mutations. (thebrf.org)
  • These can be a short section of a gene or other DNA element that are used to hybridize a cDNA or cRNA (also called anti-sense RNA) sample (called target) under high-stringency conditions. (wikipedia.org)
  • Many types of arrays exist and the broadest distinction is whether they are spatially arranged on a surface or on coded beads: The traditional solid-phase array is a collection of orderly microscopic "spots", called features, each with thousands of identical and specific probes attached to a solid surface, such as glass, plastic or silicon biochip (commonly known as a genome chip, DNA chip or gene array). (wikipedia.org)
  • Novel vectors for gene delivery formed by self-assembly of DNA with poly(L-lysine) grafted with hydrophilic polymers. (ox.ac.uk)
  • Analysis of a novel form of progeria caused by a mutation in a DNA repair gene has unified two competing theories of aging, according to a report in Nature . (the-scientist.com)
  • DNA has four chemical letters, called "bases": A, C, T, and G. The order of the letters determines the information carried in each gene, like the way that a specific pattern of letters makes up the words in a sentence. (cdc.gov)
  • There is a place in the FMR1 gene where the DNA pattern of the chemical letters, CGG, is repeated over and over again. (cdc.gov)
  • Although the scientists only edited out mutations that could cause diseases, it modified the nuclear DNA that sits right at the heart of the cell, which also influences personal characteristics such as intelligence, height, facial appearance and eye color. (rael.org)
  • Another claim of Russian scientists is that DNA is a biological network that binds all humans. (nature.com)
  • CRISPR-Cas is a recently developed technique that allows scientists to precisely modify the DNA of living organisms, and thus for instance change certain characteristics. (wur.nl)
  • Over the last 20 years, rapid advances in DNA sequencing and bioinformatics technologies have significantly improved scientists' understanding of the microbial world. (nau.edu)
  • The iconic 'double helix' shape of DNA has captured the public imagination since 1953, when James Watson and Francis Crick famously uncovered the structure of DNA. (sciencedaily.com)
  • The new shape looks entirely different to the double-stranded DNA double helix. (sciencedaily.com)
  • When most of us think of DNA, we think of the double helix," says Associate Professor Daniel Christ (Head, Antibody Therapeutics Lab, Garvan) who co-led the research. (sciencedaily.com)
  • Named i-motif, the form looks like a twisted 'knot' of DNA rather than the well-known double helix. (meba.ro)
  • Previously, challenges with DNA extracted from saliva included microbial contamination and lower nucleic acid yields. (isohelix.com)
  • Like other modern techniques to modify DNA, CRISPR-Cas is subject to the European GMO directive, which was upheld by the European Court of Justice in 2018. (wur.nl)
  • The chromosomes that form the 23rd pair are called the sex chromosomes. (cdc.gov)
  • The enzyme is in a recombinant form, expressed in E. coli . (sigmaaldrich.com)
  • At the same time, it warns of the potential risks of such research, in particular the possibility that recombinant DNA technology will exacerbate global health inequalities, and of the need to consider the complex ethical issues that might arise in the context of the different religious and cultural values of the individual Member States. (who.int)
  • The time has come to plan how recombinant DNA technology and its potential clinical benefits can be distributed fairly. (who.int)
  • It is unclear what the function of the i-motif is, but experts believe it could be for 'reading' DNA sequences and converting them into useful substances. (meba.ro)
  • Thus they claim that it should be principally possible to grant various types of patents directed to isolated DNA sequences and proteins. (lu.se)
  • The blood-based test for ctDNA "can detect tumor DNA in circulation and thus identify even a microscopic cancer that would not be found by other conventional modalities like endoscopy or radiographic imaging," Apaar Dadlani, MBBS, who was an internal medicine resident at the University of Louisville in Kentucky at the time of the study, told Medscape Medical News . (medscape.com)
  • Identification and susceptibility testing of isolates v1.1 Cycle Sequencing Ready Reaction Kit and a 3100 obtained through 2000 were performed by using the capillary DNA sequencer (Applied Biosystems, VITEK1 System with AMS R09.1 software (bioMérieux, Nieuwerkerk a/d Yssel, the Netherlands). (cdc.gov)
  • Material: This paper examines polyacrylamide gel images from Li-Cor DNA Sequencer 4300S resulting from the use of the electrophoretic separation of DNA fragments. (researchgate.net)
  • That's important,' Ortiz-Rodríguez said, 'because we need and want to know how fast the mutations can form in the DNA, so that maybe researchers can find a better way to prevent skin cancer at a cellular level. (news-medical.net)
  • You're forming these mutations in your skin every second that you are exposed to sunlight, but enzymes in your cells repair more than 99% of them,' Crespo said. (news-medical.net)
  • Mutations caused by oxidative DNA damage may contribute to human disease. (psu.edu)
  • In the case of Escherichia coli DNA topoisomerase I, it has been suggested that a 30 kDa fragment moves away from the rest of the protein to create an entrance into the central hole in the protein. (rcsb.org)
  • Then the day came when he peered through an ultrafast laser spectrometer at the College of Arts & Sciences at Case Western Reserve University and observed and recorded pre-cancerous lesions forming on the DNA within three picoseconds after exposure to ultraviolet light. (news-medical.net)
  • New research by Ortiz-Rodríguez and mentor Carlos Crespo, a professor and lead researcher in the The Crespo Group lab, reveals for perhaps the first time how quickly certain pre-cancerous lesions can form on the DNA of our skin when exposed to sunlight. (news-medical.net)
  • They believe their findings will provide a stepping-stone toward a fuller understanding of how skin cancerous lesions actually form--a discovery that Crespo believes could have a big impact on the economics of treating and preventing skin cancer. (news-medical.net)
  • Silica gel capsules that are designed to fit perfectly in to SK-1S tubes for long term stabilization of buccal cell DNA samples. (isohelix.com)
  • Traditionally blood samples were shipped and stored at -20 degrees before processing, but DNA stabilization reagents are now available for collecting, transporting, and storing whole blood. (isohelix.com)
  • Together they form a unique fingerprint. (psu.edu)
  • The GFX-01 is a high performing and easy to use saliva collection device for collecting 1ml of saliva DNA/RNA. (isohelix.com)
  • The GFX-02 is designed for collecting 2ml of saliva DNA/RNA for applications that demand greater yields. (isohelix.com)
  • The GFXA-01 includes absorbent foam swabs for assisted collection of 1ml of saliva DNA/RNA when self collection is not possible. (isohelix.com)
  • Which cells provide the DNA extracted from saliva and blood samples? (isohelix.com)
  • Human DNA in saliva originates from epithelial cells or or leukocytes. (isohelix.com)
  • Unlike DNA derived from blood, saliva samples can include bacterial DNA, allowing DNA extraction from the oral microbiome. (isohelix.com)
  • If required, qPCR assays can be used to quantify either human or bacterial DNA and measure and normalize saliva DNA samples. (isohelix.com)
  • In a study comparing DNA extracted from saliva and blood, Looi et al [iv] ( 2012), the DNA yield from saliva of 7.8 µg/0.5 mL from a manual purification method was comparable to the DNA yield from blood using a salt precipitation method (7.4 µg/0.5 mL blood sample). (isohelix.com)
  • Below are some recent studies demonstrating the successful use of DNA from saliva extracted using Isohelix kits. (isohelix.com)
  • DNA extracted from saliva is routinely used for PCR and qRT-PCR and became particularly important during the Covid 19 pandemic. (isohelix.com)
  • Isohelix estimated the relative quantities of human and microbial DNA found in samples stabilized using their GeneFix reagent, which were then stored at room temperature prior to DNA extraction [i]. (isohelix.com)
  • Approximately 7.4% of DNA in the samples was found to be of microbial origin. (isohelix.com)
  • The authors conclude that guanine is the major site for DNA modification by styrene -oxide. (cdc.gov)
  • The capturing of gel electrophoresis image represents the output of a DNA computing algorithm. (researchgate.net)
  • Isohelix DNA extraction kits are designed specifically for buccal swab samples to achieve better yields and quality than the equivalent generic kit. (isohelix.com)
  • The presented image analysis method was performed on gel images resulting from the analysis of DNA methylome profiling in plants exposed to drought stress, carried out with the MSAP (Methylation Sensitive Amplification Polymorphism) technique. (researchgate.net)
  • Melting temperature is a unique characteristic to ma- nipulate the hybridization and denaturation processes that used in the key steps in DNA computing such as the solution generation step and the amplification step. (researchgate.net)
  • Although this can seriously undermine genome integrity, the fate of DNA with unresolved replication intermediates is not known. (ku.dk)
  • Together, these data indicate that restoration of DNA or chromatin integrity at loci prone to replication problems requires mitotic transmission to the next cell generations. (ku.dk)
  • In this paper we showed that the ATP-dependent chromatin remodelling INO80 complex promotes resolution of R-loops to prevent replication-associated DNA damage in cancer cells. (leica-microsystems.com)
  • About impressionability of DNA from the wave frequency, many experimental research studies have been carried out which have opened a new branch in science, called wave genome. (nature.com)
  • With genome-wide association studies, researchers are learning so much about someone's DNA that findings incidental to the original research may be detected. (cdc.gov)
  • Use this form for specimens with rusty-colored spores and a veil or cortina. (wpamushroomclub.org)
  • Names(s) of person(s) annotaing the specimens, may be different form the collectors. (wpamushroomclub.org)
  • Use of the NHANES DNA specimens is governed by a proposal process. (cdc.gov)
  • A . We actually started asking people if we can store specimens in the later part of NHANES III (Phase II), so we have DNA specimens from 1991. (cdc.gov)
  • To date, we've collected DNA specimens from 28,600 adult participants. (cdc.gov)
  • A. No, we stopped collecting DNA specimens in January 2013. (cdc.gov)
  • 218-amino acid protein, protects DNA gyrase and topoiso- trophoresis (PFGE) typed isolates obtained from January merase IV from the inhibitory activity of quinolones ( 2 ). (cdc.gov)
  • In contrast to tailed icosahedral double-stranded DNA (dsDNA) viruses infecting bacteria and archaea, and herpesviruses infecting animals and humans, where naked DNA is packed under very high pressure due to the repulsion between adjacent layers of DNA, the circular dsDNA in SPV1 is fully covered with a viral protein forming a nucleoprotein filament with attractive interactions between layers. (hal.science)
  • Thus, the grant of patents on DNA- and protein- related technology had become routine. (lu.se)
  • More specifically, it investigates how the European and US patent systems interpret and apply the so called "inventive step" (Europe) or "non-obviousness" requirement (U.S.) vis-à-vis bio-pharmaceutical technology with a special emphasis on DNA-and protein related inventions. (lu.se)
  • Complexes formed with all polymer conjugates showed greater aqueous solubility than simple pLL/DNA complexes, particularly at charge neutrality. (ox.ac.uk)
  • A DNA microarray (also commonly known as DNA chip or biochip) is a collection of microscopic DNA spots attached to a solid surface. (wikipedia.org)
  • The CRISPR-Cas system works at the microscopic level: using a kind of template, it finds a specific piece of DNA in a cell and then removes, replaces or inserts a piece of DNA at this location. (wur.nl)
  • Understanding the chemical processes could help us design better sunblock or maybe avoid the damage to the DNA before it occurs. (news-medical.net)
  • The complexes formed are discrete and typically about 100 nm diameter, viewed by atomic force microscopy. (ox.ac.uk)
  • The acquired images have a resolution dependent on the length of the analysed DNA fragments and typically it is MGxNG=3806x1027 pixels. (researchgate.net)
  • We show that the number of such 53BP1 nuclear bodies increases after genetic ablation of BLM, a DNA helicase associated with dissolution of entangled DNA. (ku.dk)
  • 3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)
  • RapiDri combines an Isohelix swab with a fast-drying pouch that stabilizes DNA samples at room temperature without the need for additional components. (isohelix.com)
  • Others, and in particular the life science industry, assert that DNA and proteins are simply chemical compounds, albeit complex ones. (lu.se)
  • In a world first, researchers have identified a new DNA structure -- called the i-motif -- inside cells. (sciencedaily.com)
  • As expected, most of the DNA recovered from the poop samples in the study belonged to frog species and plenty of lizards, but researchers also found evidence that the bats were eating other bats and even a hummingbird. (si.edu)
  • Researchers hope this finding will set the stage for a new push to understand what this new DNA shape is for and whether it will impact our understanding of health and disease. (meba.ro)
  • The second assay, a forward mutation assay, tests the mispairing potential of any altered nucleotide 1) during incorporation as substrate nucleotide, and 2) after multiple incorporations into a single-stranded DNA gap region of M13mp2. (psu.edu)
  • DNA holds the instructions for an organism or each cell development processes, reproduction and ultimately death. (nature.com)
  • They believe that any form of patenting DNA, or of the natural processes it is involved in, is utterly wrong, since any DNA and the information it contains is the embodiment of the code of life and should be regarded part of the common heritage of mankind. (lu.se)
  • The 2 capsid proteins with variant single jelly-roll folds form pentamers and hexamers which assemble into a T = 43 icosahedral shell. (hal.science)
  • Usually, the NOE and NMRD in B-DNA is expected to be less ``integral'' than methods can only provide bounds on the residence water molecules buried inside proteins. (lu.se)
  • A twisted 'knot' of DNA, the i-motif has never before been directly seen inside living cells. (sciencedaily.com)
  • The i-motif is a four-stranded 'knot' of DNA," says Associate Professor Marcel Dinger (Head, Kinghorn Centre for Clinical Genomics, Garvan),.who co-led the research with A/Prof Christ. (sciencedaily.com)
  • Laboratory experiments have shown that a sugar critical to the structure of DNA arises when ice formed on planets, asteroids and meteorites is subjected to ultraviolet radiation. (cosmosmagazine.com)
  • Going forward, this novel combination of dietary DNA analysis with behavioral experiments may be used by other ecologists interested in the foraging behaviors of a wide range of animal species. (si.edu)
  • Greg Braddon and colleagues in 3 experiments investigated the impressionability of DNA from human emotions 2 . (nature.com)
  • By the help of these results, a conceptual idea for controlling cancer with using the DNA resonance frequency is presented. (nature.com)
  • C. Bottari , I. Mancini , A. Mele , A. Gessini , C. Masciovecchio , and B. Rossi "Conformational stability of DNA in hydrated ionic liquid by synchrotron-based UV resonance raman", Proc. (spiedigitallibrary.org)
  • In humans, for example, this information determines our eye and hair colour, and the DNA in plants determines characteristics such as the length and thickness of their roots. (wur.nl)
  • The result adds to evidence that organic molecules can form under non-biological conditions, and extends the argument that the substances needed for life to emerge on Earth may have originally come from outer space. (cosmosmagazine.com)
  • DNA carries the genetic code of life, with different conformations associated with different biological functions. (lu.se)
  • We are trying to improve biological properties of such complexes by oriented self-assembly of DNA with cationic-hydrophilic block copolymers, designed to enshroud the complex within a protective hydrophilic polymer corona. (ox.ac.uk)
  • These materials appear to have the ability to regulate the physicochemical and biological properties of polycation/DNA complexes, and should find important applications in packaging of nucleic acids for specific biological applications. (ox.ac.uk)
  • On the other hand, it is said that under the influence of acoustic, electromagnetic, and scalar waves, the genetic code of DNA can be read or rewritten. (nature.com)
  • The Innocence Project, which is affiliated with Benjamin N. Cardozo School of Law at Yeshiva University, is a national litigation and public policy organization dedicated to exonerating wrongfully convicted people through DNA testing and reforming the criminal justice system to prevent future injustice. (innocenceproject.org)
  • Waller, who has been on parole for several years and will appear in court today, is the twelfth Dallas County man in five years who has been proven innocent through DNA testing - the latest in what the Innocence Project said is an 'alarming and completely unprecedented' pattern of wrongful convictions in one county. (innocenceproject.org)
  • Waller and his attorneys - Barry Scheck and Nina Morrison of the Innocence Project, with Jeff Blackburn of the Innocence Project of Texas and Houston attorney Randy Schaffer, who worked on Waller's case in his earlier attempts to secure DNA testing - will speak to reporters after the hearing. (innocenceproject.org)
  • In 2004, the Innocence Project helped secure a previously unavailable type of DNA testing (on liquid extracts of the evidence, since the evidence was consumed during the inconclusive tests by the state lab), and the results show that Waller is innocent. (innocenceproject.org)
  • To writer Sumiko Saulson, who still has their humanity intact, and to the Innocence Project, the story and path of Pervis Payne appears clear - he has been wrongly convicted and sentenced to be executed, although new DNA testing has not revealed his DNA on the weapon and he has intellectual disability. (sfbayview.com)
  • They've been falsely convicted, without DNA evidence, but the truth of the case is finally revealed with their release. (ipl.org)
  • Through DNA testing, they have been able to find new evidence that have freed hundreds of prisoners who were wrongfully convicted. (ipl.org)
  • Pervis Payne remains on death row despite DNA evidence, new date. (sfbayview.com)
  • The Denver Post reports that a man convicted and sentenced to life in prison for raping and murdering a young woman nearly twenty years ago has been cleared of that crime based on DNA evidence. (stevenlouth.com)
  • While the DNA evidence was available at the original trial for the 1989 crime, advances in the ability to analyze and handle DNA in the intervening years allowed for a new examination of the evidence, which not only points away from the man originally convicted, but toward another man who is currently serving time for another similar crime. (stevenlouth.com)
  • The man who the DNA evidence now points to would currently be eligible for parole from the other crime in 2035. (stevenlouth.com)
  • A new form of DNA has been discovered inside living human cells for the first time. (meba.ro)
  • General Assembly the adoption of a declaration on human cloning by which Member States were called upon to prohibit all forms of human cloning inasmuch as they are incompatible with human dignity and the protection of human life. (who.int)
  • Some people believe for multiple reasons that DNA, and in particular human DNA, is much more than a mere chemical structure. (lu.se)
  • What excited us most is that we could see the green spots -- the i-motifs -- appearing and disappearing over time, so we know that they are forming, dissolving and forming again," says Dr Mahdi Zeraati, whose research underpins the study's findings. (sciencedaily.com)
  • A/Prof Marcel Dinger says, "It's exciting to uncover a whole new form of DNA in cells -- and these findings will set the stage for a whole new push to understand what this new DNA shape is really for, and whether it will impact on health and disease. (sciencedaily.com)
  • Our findings show that ecDNA can develop early in the transition from high-grade dysplasia to cancer, and that ecDNAs progressively form and evolve under positive selection. (nature.com)
  • But he also displayed the increased sun sensitivity that is the hallmark of a DNA repair. (the-scientist.com)
  • Poly(L-lysine) (pLL) grafted with range of hydrophilic polymer blocks, including poly(ethylene glycol) (pEG), dextran and poly[N-(2-hydroxypropyl)methacrylamide] (pHPMA), shows efficient binding to DNA and mediates particle self-assembly and inhibition of ethidium bromide/DNA fluorescence. (ox.ac.uk)
  • This graph shows the total number of publications written about "DNA, C-Form" by people in this website by year, and whether "DNA, C-Form" was a major or minor topic of these publications. (jefferson.edu)
  • The intersection of form and function: Disruptions in DNA's 3D-structure linked to neurodevelopmental brain disorders. (thebrf.org)
  • Also, in this model, the mass of the nucleobases in the DNA structure, the effects of the fluid surrounding the DNA (nucleoplasm) and the effects of temperature changes are also considered. (nature.com)
  • Previous studies have suggested that DNA is in the B-form in bacteriophages, and our study is a direct visualization of the structure of DNA in an icosahedral virus. (hal.science)
  • Eisenstein & Shakked, 1995) and drugs (Kopka mation about the hydration structure of DNA has et al. (lu.se)