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  • cells
  • Upon in vitro restimulation with infected antigen-presenting cells, CD8(+) T cells from acutely infected susceptible neonates acquired strong MT389-specific cytotoxicity. (nih.gov)
  • requirements
  • This and nonexistent testing requirements led to the elixir sulfanilamide disaster in the fall of 1937, during which at least 100 people were poisoned with diethylene glycol. (wikipedia.org)
  • Testing included amounts of selected index elements, their ability to disintegrate in solution per United States Pharmacopeia guidelines, lead contamination threshold set in California Proposition 65, and meeting U.S. Food and Drug Administration (FDA) labeling requirements. (wikipedia.org)
  • activate
  • Although activation of natural killer (NK) cytotoxicity is generally inhibited by target major histocompatibility complex (MHC) class I expression, subtle features of NK allorecognition suggest that NK cells possess receptors that are activated by target MHC I. The mouse Ly-49D receptor has been shown to activate NK cytotoxicity, although recognition of MHC class I has not been demonstrated previously. (nih.gov)
  • cells
  • It remains unclear whether the immunologic status of cells in peripheral blood can be used as a prognostic indicator of response to treatment for patients with unresectable metastatic colorectal cancer (MCRC). (aacrjournals.org)
  • In different studies, NK cytotoxicity, leukocytes' molecular functional markers, and vascular endothelial growth factor secretion by tumor cells were studied in the context of surgery and drug treatments. (jimmunol.org)
  • RNK.mLy-49D transfectants were tested as effector cells for lysis of Con A blast targets prepared from mice that were congenic resistant at the H-2 locus. (nih.gov)
  • cell
  • Surgery markedly reduced NK cytotoxicity and NK cell expression of Fas ligand and CD11a, reduced all circulating lymphocyte-subtype concentrations, and increased corticosterone levels. (jimmunol.org)
  • Mouse Ly-49D recognizes H-2Dd and activates natural killer cell cytotoxicity. (nih.gov)
  • Initial characterization of its biological activities revealed that IL-12, when added to human peripheral blood lymphocytes, induced IFN-γ production, increased NK cell cytotoxicity as well as T cell proliferation in response to mitogenic lectins and phorbol diesters (see ref. 11 for review). (aacrjournals.org)
  • GBS is characterized by the presence in the cell wall of the group B antigen of the Lancefield classification (Lancefield grouping) that can be detected directly in intact bacteria using latex agglutination tests. (wikipedia.org)
  • therefore
  • We therefore investigated the relationship between the pretreatment immunologic status of 40 patients with MCRC who planned to receive the first-line chemotherapy and their progression-free survival. (aacrjournals.org)
  • Therefore, MSCs of dental origin have been tested as candidates for cellular therapy of stomatognathic disorders, such as periodontal disease (PD), and for maxillofacial reconstruction. (hindawi.com)
  • study
  • In this study, in mice undergoing primary tumor excision, we tested the survival-enhancing potential of perioperative blockade of catecholamines and prostaglandins, and studied potential mediating mechanisms. (jimmunol.org)
  • requirements
  • Testing included amounts of selected index elements, their ability to disintegrate in solution per United States Pharmacopeia guidelines, lead contamination threshold set in California Proposition 65, and meeting U.S. Food and Drug Administration (FDA) labeling requirements. (wikipedia.org)
  • This and nonexistent testing requirements led to the elixir sulfanilamide disaster in the fall of 1937, during which at least 100 people were poisoned with diethylene glycol. (wikipedia.org)