• The 11 species in this genus include human betaherpesvirus 5 (HCMV, human cytomegalovirus, HHV-5), which is the species that infects humans. (wikipedia.org)
  • The most studied is Human cytomegalovirus (HCMV), which is also known as Human betaherpesvirus 5 (HHV-5). (wikipedia.org)
  • Human Cytomegalovirus (CMV) is a member of the family Herpesviridae, also known as Human Herpesvirus 5 (HHV-5). (medscape.com)
  • The Human Cytomegalovirus (HCMV) Immediate-Early protein 1 (IE1) is the first viral protein to express during infection. (ncbs.res.in)
  • Is the Subject Area "Human cytomegalovirus" applicable to this article? (plos.org)
  • It is a bivalent vaccine containing two recombinant, replication-deficient lymphocytic choriomeningitis virus (rLCMV) vectors, one expressing the pp65 protein and one expressing the gB protein of human cytomegalovirus (HCMV). (pharmaceutical-technology.com)
  • Human cytomegalovirus (HCMV) purified from cell culture contains two dominant structural phosphoproteins with apparent molecular weights of 65000 and 150000, designated as pp65 and ppl50 respectively. (microbiologyresearch.org)
  • Neutralizing antibodies detect a disulfide-linked glycoprotein complex within the envelope of human cytomegalovirus. (microbiologyresearch.org)
  • Identification of a 65000 dalton virion envelope protein of human cytomegalovirus. (microbiologyresearch.org)
  • Synthesis and processing of the envelope gp55-116 complex of human cytomegalovirus. (microbiologyresearch.org)
  • Nucleotide sequence of a human cytomegalovirus DNA fragment encoding a 67-kilodalton phosphorylated viral protein. (microbiologyresearch.org)
  • Characterization of the human cytomegalovirus envelope glycoproteins. (microbiologyresearch.org)
  • A 64,000 dalton matrix protein of human cytomegalovirus induces in vitro immune responses similar to those of whole viral antigen. (microbiologyresearch.org)
  • Selection of particles and proteins for use as human cytomegalovirus subunit vaccines. (microbiologyresearch.org)
  • The Human Cytomegalovirus Latency-Associated Gene Product Latency Unique Natural Antigen Regulates Latent Gene Expression. (cam.ac.uk)
  • Human cytomegalovirus (HCMV) infection can lead to either lytic or latent infection, which is dependent on the regulation of the viral major immediate early promoter (MIEP). (cam.ac.uk)
  • Human cytomegalovirus (CMV) infection is reported to promote NK cell differentiation and education. (aacrjournals.org)
  • The development of a vaccine against human cytomegalovirus infection (HCMV) is a high-priority medical goal. (asm.org)
  • IMPORTANCE Infections with the human cytomegalovirus (HCMV) may cause severe and even life-threatening disease manifestations in newborns and immunosuppressed individuals. (asm.org)
  • Congenital human cytomegalovirus infection (cCMV) is a major cause of childhood disease, often leading to permanent neurologic sequelae ( 1 ). (asm.org)
  • Human Cytomegalovirus (HCMV) is a ubiquitous member of the Herpesviridae family , responsible for the most common congenital viral infection - congenital Cytomegalovirus (cCMV) infection . (bvsalud.org)
  • When a baby is born with cytomegalovirus (CMV) infection, it is called congenital CMV. (cdc.gov)
  • As the name indicates, cytomegalovirus (CMV) disease is a virus infection. (encyclopedia.com)
  • Cytomegalovirus (CMV) has three major patterns of infection. (medscape.com)
  • A recent study found that a latent cytomegalovirus infection can have a negative effect on mRNA vaccine responsiveness to COVID-19 infection. (ajmc.com)
  • Health care workers (HCWs) had a lower vaccine response to COVID-19 infection when they had a latent cytomegalovirus (CMV) infection, according to a study published in Open Forum Infectious Diseases . (ajmc.com)
  • Cytomegalovirus, a member of the herpesvirus family, is related to the viruses that cause chickenpox and mononucleosis ("mono"), and is a common cause of viral infection . (akronchildrens.org)
  • Collectively, our data demonstrate that the ability of NK cells to respond very early to cytomegalovirus infection critically contributes to balance the intensity of other innate immune responses, which dampens early immunopathology and promotes optimal initiation of antiviral CD8 T cell responses. (uni-muenchen.de)
  • HIV related cytomegalovirus (CMV) disease results from reactivation of latent infection when the CD4 count falls below 100 cells ×10 6 /l. (bmj.com)
  • OBJECTIVE To assess the role of cytomegalovirus (CMV) infection in primary ischaemic heart disease. (bmj.com)
  • Cytomegalovirus infection is caused by a virus. (msdmanuals.com)
  • Cytomegalovirus infection cannot be cured, but some antivirals can limit the problems caused by infection. (msdmanuals.com)
  • Cytomegalovirus (CMV) Infection Cytomegalovirus infection is a common herpesvirus infection with a wide range of symptoms: from no symptoms to fever and fatigue (resembling infectious mononucleosis) to severe symptoms involving. (msdmanuals.com)
  • Infection with cytomegalovirus (CMV) is very common. (msdmanuals.com)
  • Congenital Cytomegalovirus and Neonatal Herpes Simplex Virus Infections: To Treat or Not to Treat? (lww.com)
  • Congenital cytomegalovirus infections are among the most common of the newborn in the developed world. (lww.com)
  • Over the past 2 decades, therapies have been recommended by the American Academy of Pediatrics Red Book Committee for the management of neonatal herpes simplex virus (HSV) and congenital cytomegalovirus (CMV) infections. (lww.com)
  • HB-101 is under clinical development by Hookipa Pharma and currently in Phase II for Cytomegalovirus (HHV-5) Infections. (pharmaceutical-technology.com)
  • According to GlobalData, Phase II drugs for Cytomegalovirus (HHV-5) Infections have a 52% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. (pharmaceutical-technology.com)
  • HB-101 (Vaxwave) is under development for the prevention of cytomegalovirus infections in solid organ transplant patients. (pharmaceutical-technology.com)
  • Antiviral Treatment of Maternal and Congenital Cytomegalovirus (CMV) Infections. (bvsalud.org)
  • Cytomegalovirus (CMV) and herpes simplex virus (HSV) active infections (detected by DNA-PCR, confirmed by serology) were found in the perilymphatic fluid of 16.7% (3/18) cases of idiopathic SNHL. (who.int)
  • The New York State Department of Health announced that as of Monday, October 2, 2023, all samples received by the New York State Newborn Screening Program will be screened for congenital cytomegalovirus (cCMV). (wadsworth.org)
  • We report the crystal structure of the cysteine protease domain of murine cytomegalovirus M48 (M48(USP)) in a complex with a ubiquitin (Ub)-based suicide substrate. (rcsb.org)
  • The treatment of symptomatic congenital cytomegalovirus (CMV) disease with intravenous ganciclovir for 6 weeks has been shown to improve audiologic outcomes at 6 months, but the benefits wane over time. (nih.gov)
  • Background: Epstein-Barr virus (EBV) and cytomegalovirus (CMV) are ubiquitous and persistent herpesviruses commonly acquired during childhood. (lu.se)
  • this genus contains Mouse cytomegalovirus (MCMV) is also known as Murid betaherpesvirus 1 (MuHV-1) and the closely related Murid betaherpesvirus 2 (MuHV-2) that is found in rats. (wikipedia.org)
  • To address this question, we took advantage of the well-defined molecular interactions involved in the recognition of mouse cytomegalovirus (MCMV) by NK cells. (uni-muenchen.de)
  • cytomegalovirus immune globulin (CMV IG) decreases effects of BCG vaccine live by pharmacodynamic antagonism. (medscape.com)
  • The FDA has approved the antiviral letermovir for cytomegalovirus (CMV) prophylaxis in adult recipients of a CMV-seropositive kidney transplant. (renalandurologynews.com)
  • Cytomegalovirus (CMV) is a member of the Herpesviridae family, along with herpes simplex viruses 1 and 2 , Epstein-Barr virus , and varicella-zoster virus . (medscape.com)
  • CMV (cytomegalovirus) is a type of herpes virus. (rochester.edu)
  • Today, Alice's child is battling with Cytomegalovirus (CMV), the largest of the herpes viruses that causes a wide range of diseases that affect the eyes, food pipe (esophagus), liver and the brain in people with low immunity. (monitor.co.ug)
  • Congenital Cytomegalovirus and Neonatal Herpes Simplex Virus. (lww.com)
  • Raglow Z and Kaul DR. A new antiviral option for cytomegalovirus prevention after kidney transplant . (renalandurologynews.com)
  • Among participants aged 6-49 years in NHANES between 1999 and 2004 who were cytomegalovirus (CMV) IgG positive, had stored urine samples available, tested and found with urinary CMV shedding and sufficient DNA for genotyping. (cdc.gov)
  • Rapid Genotyping of Cytomegalovirus in Dried Blood Spots by Multiplex Real-Time PCR Assays Targeting the Envelope Glycoprotein gB and gH Genes 2012. (cdc.gov)
  • Genotyping of cytomegalovirus (CMV) is useful to examine potential differences in the pathogenicity of strains and to demonstrate coinfection with multiple strains involved in CMV disease in adults and congenitally infected newborns. (eur.nl)
  • Background/aim: Cytomegalovirus (CMV) hepatitis is generally asymptomatic or rarely can lead to severe complications in immunocompetent hosts. (tubitak.gov.tr)
  • The following 11 species are assigned to the genus in ICTV 2022: Cytomegalovirus aotinebeta1 Cytomegalovirus cebinebeta1 Cytomegalovirus cercopithecinebeta5 Cytomegalovirus humanbeta5 Cytomegalovirus macacinebeta3 Cytomegalovirus macacinebeta8 Cytomegalovirus mandrillinebeta1 Cytomegalovirus paninebeta2 Cytomegalovirus papiinebeta3 Cytomegalovirus papiinebeta4 Cytomegalovirus saimiriinebeta4 Viruses in Cytomegalovirus are enveloped, with icosahedral, spherical to pleomorphic, and round geometries, and T=16 symmetry. (wikipedia.org)
  • Aims The aim of this observational study was to report the distribution of glycoprotein B (gB) genotypes in the eyes of cytomegalovirus (CMV) positive patients with Posner-Schlossman syndrome (PSS), and to investigate their clinical characteristics and outcomes. (bmj.com)
  • Cytomegalovirus (CMV) antibody. (euroimmun.de)
  • Antibody response to cytomegalovirus polypeptides captured by monoclonal antibodies on the solid phase in enzyme immunoassays. (microbiologyresearch.org)
  • We report a case of cytomegalovirus (CMV) disease complicating treatment with an IL-6 receptor antagonist. (cdc.gov)
  • The cytomegalovirus (cmv) tests market in the Netherlands can expand or contract due to a variety of reasons including population demographics, disease incidence and prevalence, macroeconomic issues, and geopolitical considerations. (medicaldevice-network.com)
  • Is cytomegalovirus viraemia a useful tool in managing CMV disease? (bmj.com)
  • The CMV Test market includes the sub-segments Cytomegalovirus (CMV) Enzyme Immuno Assay/Enzyme Linked Immunosorbent Assay (EIA/ELISA) Tests, Cytomegalovirus (CMV) Nucleic Acid Amplification Tests (NAATs), and Other Cytomegalovirus (CMV) Tests. (medicaldevice-network.com)
  • Giant cell with inclusion body characteristic of cytomegalovirus colitis. (medscape.com)
  • Porcine cytomegalovirus (PCMV), also known as inclusion body rhinitis (IBR) occurs in all age groups of previously uninfected swine, including developing fetuses. (iastate.edu)
  • A further two viruses found in the night monkey are tentatively placed in the genus Cytomegalovirus, and are called Herpesvirus aotus 1 and Herpesvirus aotus 3. (wikipedia.org)
  • Cytomegalovirus (CMV) (from cyto- 'cell' via Greek κύτος kútos- 'container' + μέγας mégas 'big, megalo-' + -virus via Latin vīrus 'poison') is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Betaherpesvirinae. (wikipedia.org)
  • efgartigimod alfa will decrease the level or effect of cytomegalovirus immune globulin (CMV IG) by receptor binding competition. (medscape.com)
  • Over half of adults are believed to have been infected with Cytomegalovirus or CMV by age 40. (monitor.co.ug)
  • Cytomegalovirus (CMV) tests are used for the detection of CMV, which can cause serious illness in immunocompromised patients, and infants, with up to 1 in 3 children being infected and over half of adults by the age of 40 in the United States. (medicaldevice-network.com)
  • By age 40, between 50% and 80% of adults in the United States have already been infected by the cytomegalovirus. (hearinglosshelp.com)
  • https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. (loinc.org)
  • Cytomegalovirus hepatitis in 49 pediatric patients with normal immunit" by HASAN TEZER, SALİHA KANIK YÜKSEK et al. (tubitak.gov.tr)
  • Cytomegalovirus in Pediatric Hema. (unige.ch)
  • Cytomegalovirus (CMV) remains a significant contributor to morbidity and death after pediatric solid and stem cell transplantation. (unige.ch)
  • Several species of Cytomegalovirus have been identified and classified for different mammals. (wikipedia.org)
  • Cytomegalovirus (CMV) is the major opportunistic virus encountered after organ transplantation, and resistant variants can make antiviral treatment challenging. (aruplab.com)
  • Cytomegalovirus (CMV) tests are used to detect the presence of the CMV virus in the body. (angis.org.au)
  • A CMV test is a blood test that is done to check for the presence of cytomegalovirus (CMV). (angis.org.au)
  • Most people don't know they have cytomegalovirus (CMV) because it rarely causes problems in healthy people. (mayoclinic.org)