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  • Depocyt
  • Cytarabine also comes in a long-acting form (DepoCyt™) that may be placed under the skin in a reservoir, with a catheter leading to the brain. (unm.edu)
  • sterile
  • This medication is available in sterile vials containing a freeze-dried preparation of cytarabine 100 mg, 500 mg, or 1,000 mg (1 g) ready for dilution with appropriate solution. (pharmasave.com)
  • doses
  • citation needed] One of the unique toxicities of cytarabine is cerebellar toxicity when given in high doses, which may lead to ataxia. (wikipedia.org)
  • patients
  • We have been actively trying to negotiate borrowing and sharing of cytarabine between institutions so that patients can stay on schedule with their protocol-directed treatments. (go.com)
  • Patients will usually have scheduled meetings with their healthcare provider while they are being treated with cytarabine. (unm.edu)
  • What are the common (occur in 30% or more of patients) side effects of treatment with cytarabine? (unm.edu)
  • What are the less common (occur in 10% to 29% of patients) side effects of treatment with cytarabine? (unm.edu)
  • Cytarabine may lead to suppression of menstrual cycles in females and lead to amenorrhoea and may suppress sperm production in male patients. (drugs.com)
  • Male patients undergoing cytarabine treatment should use a reliable contraceptive method. (drugs.com)
  • Furthermore, SAMHD1 has been shown to limit the efficacy of cytarabine efficacy in patients. (wikipedia.org)
  • bone
  • The main toxic effect of cytarabine is bone wmarrow suppression with leukopenia, thrombocytopenia, and anemia. (egeneralmedical.com)
  • Per animal data, liposomes are taken up intact by bone marrow cells (to a greater degree in leukemia cells versus normal bone marrow cells) and are degraded following cellular internalization, thus releasing cytarabine and daunorubicin within the cells. (drugs.com)
  • Cytarabine strongly reduces blood cell production in the bone marrow. (drugs.com)
  • However, cytarabine is not very selective in this setting and causes bone marrow suppression and other severe side effects. (wikipedia.org)
  • nucleoside
  • Cytarabine is a synthetic nucleoside which differs from the normal nucleosides cytidine and deoxycytidine in that the sugar moiety is arabinose rather than ribose on deoxyribose. (egeneralmedical.com)
  • leukemia
  • Cytarabine is also used to treat leukemia associated with meningitis. (adventisthealthcare.com)
  • ABC News heard from dozens of medical centers on reported shortages of the leukemia drug cytarabine . (go.com)
  • The] cytarabine shortage has critically affected our leukemia clinical trials being run by the CALGB at member institutions across the country. (go.com)
  • drug
  • The physician must judge possible benefit to the patient against known toxic effects of this drug in considering the advisability of therapy with cytarabine. (egeneralmedical.com)