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  • doses
  • Compare the effectiveness of two doses of cyproterone acetate in these patients. (knowcancer.com)
  • Estradiol undecylate, in combination with norethisterone acetate (at doses of 5 mg and 50 mg, respectively), was studied as a combined injectable contraceptive, but ultimately was not marketed for this purpose. (wikipedia.org)
  • liver
  • Liver cell proliferation induced by nafenopin and cyproterone acetate is not associated with increases in activation of transcription factors NF-kappaB and AP-1 or with expression of tumor necrosis factor alpha. (semanticscholar.org)
  • months
  • With estradiol undecylate, testosterone levels fell from 416 ng/dL to 38 ng/mL after 3 months and to 29.6 ng/dL after 6 months, whereas with cyproterone acetate, testosterone levels fell from 434 ng/dL to 107 ng/mL at 3 months and to 102 ng/mL at 6 months. (wikipedia.org)
  • Anti-Androgen
  • It is an antipsychotic, which can be used for the treatment of schizophrenia, but it is primarily used to control antisocial hypersexual behaviour, and is sometimes prescribed to sex offenders as a condition of their parole, as an alternative to anti-androgen drugs such as cyproterone acetate. (wikipedia.org)
  • derivative
  • Chronologically, the progestagens can be well recognised, with one in particular: The successful derivative, cyproterone acetate (CPA). (uantwerpen.be)
  • An acylated derivative, anagestone acetate, was formerly used clinically as a pharmaceutical drug. (wikipedia.org)
  • DMA, also known as 1-dehydrochlormadinone acetate, as well as 1,6-didehydro-6-chloro-17α-acetoxyprogesterone or '6-chloro-17α-hydroxypregna-1,4,6-triene-3,20-dione, is a synthetic pregnane steroid and a derivative of progesterone. (wikipedia.org)
  • It is specifically a derivative of 17α-hydroxyprogesterone with a chlorine atom at the C6 position, a double bond between the C1 and C2 positions, another double bond between the C6 and C7 positions, and an acetate ester at the C17α position. (wikipedia.org)
  • antagonists
  • Some steroid antagonists: Androgen: cyproterone acetate Progestins: mifepristone, gestrinone Steroid hormones are transported through the blood by being bound to carrier proteins-serum proteins that bind them and increase the hormones' solubility in water. (wikipedia.org)
  • main
  • It can also be concluded that adult man and rhesus monkey are much less sensitive, if at all so, to some corticosteroid-like activities of cyproterone acetate and its main metabolites than the rat. (wikipedia.org)
  • active
  • However, there was a general increase in the level of blood glucose and liver glycogen as well as a reduction in body weight and organ weight (spleen, thymus and adrenal) in rats, in which 15β-hydroxy cyproterone was slightly more active with the exception of adrenal weight reduction, which was almost equal in all three compounds tested. (wikipedia.org)