• Cryptococcosis is an infection caused by the encapsulated yeast Cryptococcus neoformans and Cryptococcus gattii . (medscape.com)
  • Cutaneous Cryptococcus infection should be presumed to be disseminated until proven otherwise, and a search for other sites of involvement must be immediately undertaken. (medscape.com)
  • In a study of 40 HIV-negative patients with Cryptococcus infection, 65% had an associated underlying condition. (medscape.com)
  • Cryptococcus infection occurs primarily from the inhalation of infectious yeast from contaminated soil. (medscape.com)
  • Cryptococcosis is a fungal infection caused by numerous species, two of which cause the majority of cryptococcal infections in humans and animals: Cryptococcus neoformans and Cryptococcus gattii, according to the Centers for Disease Control and Prevention . (outbreaknewstoday.com)
  • We investigated the pathogenesis of pulmonary Cryptococcus neoformans infection and passive Ab efficacy in mice deficient in inducible NO synthase (NOS2 -/- ) and the parental strain. (elsevierpure.com)
  • We are interested in elucidating the process of melanogenesis in Cryptococcus neoformans, where melanin plays a key role during infection. (jhu.edu)
  • Sarah Gregory] Vancouver Island, Canada, reports the world's highest incidence of Cryptococcus gattii infection among humans and animals. (cdc.gov)
  • Bacterial and viral are the more prevalent and commonly discussed forms of meningitis, but one infectious disease expert at the University of Alabama at Birmingham says fungal meningitis stemming from Cryptococcus is the true "hidden epidemic" needing more attention - as it is deadly if it goes undiagnosed. (outbreaknewstoday.com)
  • The combined administration of an efflux inhibitor with itraconazole should increase cerebral itraconazole concentrations and therefore, improve the treatment of Cryptococcus neoformans meningitis with this antifungal agent. (pasteur.fr)
  • Although the focus of this draft global road map is not on other important causes of meningitis, such as tuberculosis, cryptococcus, enteric bacteria and viruses such as enterovirus, several goals directed at reducing the burden of disease are applicable to all causes of meningitis. (who.int)
  • describir las características epidemiológicas de las meningitis, en pacientes de todas las edades internados en el lapso de enero del 2014 a octubre del 2015 en el Hospital Nacional de Itauguá, Paraguay. (bvsalud.org)
  • Se incluye a pacientes de todas las edades que ingresaron con sospecha de meningitis y/o encefalitis en el periodo de estudio. (bvsalud.org)
  • en el periodo de estudio ingresaron 173 casos probables de 201 casos sospechosos de meningitis correspondiendo al 0,5% (173/35140) de todos los ingresos hospitalarios. (bvsalud.org)
  • No se ha registrado vacunación para N. meningitis en ningún caso. (bvsalud.org)
  • la incidencia total de meningitis en este periodo de estudio fue de 173 casos. (bvsalud.org)
  • La letalidad fue de 3% en los casos de encefalitis viral, 14% en meningitis bacteriana aguda y 43% en meningitis a Criptococcus. (bvsalud.org)
  • 7 cases (4%) Fungal Meningitis (Cryptococcus). (bvsalud.org)
  • 14% in MBA and 43% in Cryptococcus meningitis. (bvsalud.org)
  • Following changes to the International Code of Nomenclature for algae, fungi, and plants, the practice of giving different names to teleomorph and anamorph forms of the same fungus was discontinued, meaning that Filobasidiella became a synonym of the earlier name Cryptococcus. (wikipedia.org)
  • Cryptococcus luteus is parasitic on Granulobasidium vellereum, a corticioid fungus, and is known from England and Italy. (wikipedia.org)
  • As a life-threatening fungus, Cryptococcus gattii ( C gattii ) species complex is emerging worldwide. (researchsquare.com)
  • Cryptococcus neoformans is an opportunistic pathogenic fungus of human beings that infects mainly immunocompromised patients. (unifesp.br)
  • The fungus Cryptococcus can be found all around the world, and most of us are likely to breathe it in at some point in our lives. (cnn.com)
  • Cryptococcus -- here's an example of a skin lesion caused by the fungus. (cnn.com)
  • There are over 30 different species of Cryptococcus -- here's an example of a skin lesion caused by the fungus. (cnn.com)
  • Christopher Uejio] Cryptococcus gattii is a fungus that can cause illness in humans and animals. (cdc.gov)
  • Christopher Uejio] People and animals living in areas with Cryptococcus gattii breathe in the microscopic fungus. (cdc.gov)
  • however, serotype A has been proposed to be reclassified into a separate variety Cryptococcus neoformans var grubii . (medscape.com)
  • Cryptococcus is a genus of fungi in the family Cryptococcaceae that includes both yeasts and filamentous species. (wikipedia.org)
  • Most yeast species formerly referred to Cryptococcus have now been placed in different genera. (wikipedia.org)
  • Some Cryptococcus species cause a disease called cryptococcosis. (wikipedia.org)
  • As a result, some ten species are currently recognized in Cryptococcus. (wikipedia.org)
  • The teleomorph was first described in 1975 by K.J. Kwon-Chung, who obtained cultures of the type species, Filobasidiella neoformans, by crossing strains of the yeast Cryptococcus neoformans. (wikipedia.org)
  • Some Cryptococcus species have a huge diversity at the infraspecific level with different molecular types based on their genetic differences, mainly due to their geographical distribution, molecular characteristics, and ecological niches. (wikipedia.org)
  • Cryptococcus species are not known to produce distinct, visible fruitbodies. (wikipedia.org)
  • Cryptococcus neoformans is cosmopolitan and is the most prominent medically important species. (wikipedia.org)
  • The taxonomy of C. neoformans has been reviewed: it has now been divided into two species: Cryptococcus neoformans sensu stricto and Cryptococcus deneoformans. (wikipedia.org)
  • Cryptococcus neoformans is a yeast that is the sole species of the genus capable of causing mycotic (fungal) disease. (encyclopedia.com)
  • Scholars@Duke publication: Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species. (duke.edu)
  • Protection varied depending on the mouse strain and cryptococcal species, suggesting that a successful human subunit vaccine will need to contain multiple antigens, including ones that are species specific.IMPORTANCE The encapsulated fungi Cryptococcus neoformans and Cryptococcus gattii are responsible for nearly 200,000 deaths annually, mostly in immunocompromised individuals. (duke.edu)
  • Cryptococcal disease is acquired via inhalation of haploid yeast or basidiospores from the environment.Genus Filobasidiella contains approximately 38 Cryptococcus species. (doe.gov)
  • A few are pathogenic and constitute the pathogenic Cryptococcus species cluster. (doe.gov)
  • Two of the species, Cryptococcus neoformans and Cryptococcus bacillisporus , are the casual agents of the majority of human and animal cryptococcosis . (doe.gov)
  • Cryptococcus gattii, a species belonging to the Cryptococcus complex which occurs endemically in tropical and subtropical regions, has been reported as a causative agent of cryptococcosis in healthy individuals. (fiocruz.br)
  • Fungi of the Cryptococcus genus, mainly the species C. neoformans and C. gattii, are pathogens that cause meningoencephalitis , especially in immunocompromised individuals. (bvsalud.org)
  • Fungi of the Cryptococcus genus were isolated in 6 samples, of which 5 were identifi ed by conventional tests, such as C. neoformans and C. gattii, but these species were not confi rmed by molecular tests. (bvsalud.org)
  • If your laboratory does not currently use CGB agar for all Cryptococcus isolates, consider adding this to your laboratory's protocol. (whatcomcounty.org)
  • Similar to amphotericin B, liposomal nystatin and the parent compound nystatin also show favorable in vitro activity against most Cryptococcus neoformans isolates [ 385 , 1129 ]. (drfungus.org)
  • Azoles, particularly fluconazole and itraconazole , have been shown to have fungistatic effects against most Cryptococcus neoformans isolates [ 343 ]. (drfungus.org)
  • Although most Cryptococcus neoformans strains are susceptible to fluconazole, isolates with high MICs have been detected [ 1118 , 1742 , 2451 ]. (drfungus.org)
  • Using Etest instead of the reference microdilution method has resulted in misclassification of a number of susceptible Cryptococcus neoformans isolates as being resistant to fluconazole, itraconazole, and flucytosine [ 2378 ]. (drfungus.org)
  • A total of 476 European isolates (310 Cryptococcus neoformans var. (uludag.edu.tr)
  • The interaction between the fungal pathogen Cryptococcus neoformans and human fibronectin (HFN) was examined in this study. (unifesp.br)
  • The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. (doe.gov)
  • Emergence and pathogenicity of highly virulent Cryptococcus gattii genotypes in the northwest United States. (duke.edu)
  • Candida albicans and Cryptococcus neoformans can cause life-threatening infections, especially in immune-compromised patients. (japsonline.com)
  • Shehu A, Ismail S, Rohin MAK, Harun A, Aziz AA, Haque M. Antifungal Properties of Malaysian Tualang Honey and Stingless Bee Propolis against Candida albicans and Cryptococcus neoformans. (japsonline.com)
  • A major research area of the department is focused on understanding the ecology and pathogenesis of Cryptococcus neoformans . (jhu.edu)
  • The filamentous, sexual forms or teleomorphs were formerly classified in the genus Filobasidiella, while Cryptococcus was reserved for the yeasts. (wikipedia.org)
  • em excretas de pombos nos arredores dos grandes hospitais de Porto Alegre / Presence and susceptibility to antifungal agents of Cryptococcus spp. (bvsalud.org)
  • INTRODUCTION: Cryptococcus neoformans and Cryptococcus gattii are encapsulated basidiomycetous yeasts with worldwide distribution. (unifesp.br)
  • Cryptococcus neoformans is a yeast-like organism found commonly in pigeon bird droppings. (clevelandcliniclabs.com)
  • Cryptococcus neoformans is an encapsulated fungal organism and it can cause disease in apparently immunocompetent, as well as immunocompromised, hosts. (ensembl.org)
  • However, there has been a dearth of research on CAP-Gly proteins in fungal pathogens, including Cryptococcus neoformans, which is a global cause of fatal meningoencephalitis in immunocompromised patients. (elsevierpure.com)
  • Cryptococcus neoformans is a yeast with a prominent polysaccharide capsule. (microbeonline.com)
  • Cryptococcus neoformans is the only pathogenic yeast known to have a polysaccharide capsule. (microbeonline.com)
  • Based on the differences in capsule polysaccharides, Cryptococcus is traditionally subdivided into 5 serotypes - A, B, C, D and AD. (doe.gov)
  • Cryptococcus neoformans is a leading cause of invasive fungal infections among immunocompromised patients. (listlabs.com)
  • Os fungos do gênero Cryptococcus foram isolados em seis amostras, sendo que cinco foram identificados, pelas provas convencionais, como o C. neoformans e uma o C. gattii, porém estas espécies não foram confirmadas pelas provas moleculares. (bvsalud.org)
  • O presente estudo visa pesquisar o fungo Cryptococcus spp. (bvsalud.org)
  • He initially experienced symptoms of bilateral lower extremity lesions four months prior to presentation, during which surgical biopsy of a left lateral calf mass yielded necrotizing granulomatous inflammation with Cryptococcus . (hindawi.com)
  • Os fungos do gênero Cryptococcus , principalmente as espécies C. neoformans e C. gattii, são patógenos que causam a meningoencefalite , principalmente em indivíduos imunocomprometidos. (bvsalud.org)
  • sendo um de Cryptococcus laurentii , dois de Cryptococcus neoformans e um de Cryptococcus gattii . (ufrgs.br)
  • Sabouraud's dextrose agar ) at room temperature or 37 °C. Cryptococcus neoformans are sensitive to cycloheximide so media containing cycloheximide should be avoided. (microbeonline.com)
  • We studied the effects of Amphotericin B (AmB) on Cryptococcus neoformans using different viability methods (CFUs enumeration, XTT assay and propidium iodide permeability). (unesp.br)
  • Amphotericin B exerts a fungicidal effect on Cryptococcus neoformans [ 343 ]. (drfungus.org)
  • In vitro data suggest that activities of amphotericin B and fluconazole against Cryptococcus neoformans may be enhanced by caspofungin [ 759 ]. (drfungus.org)
  • Using glucan particles (GPs) as a delivery system, we previously demonstrated that mice vaccinated with crude Cryptococcus-derived alkaline extracts were protected against lethal challenge with Cryptococcus neoformans and Cryptococcus gattii The goal of the present study was to identify protective protein antigens that could be used in a subunit vaccine. (duke.edu)
  • The present study evaluated the efficacy of interferon-γ transgene expression by Cryptococcus neoformans strain H99γ in abrogating alternative macrophage activation in infected mice. (elsevierpure.com)
  • This case highlights the challenges that remain in improving clinical outcomes, the importance of antiretroviral therapy and HIV disease control, and a potential association between a chronic inflammatory state caused by disseminated Cryptococcus and tumorigenesis in individuals with PBL. (hindawi.com)
  • Cryptococcus gattii causes life-threatening disease in otherwise healthy hosts and to a lesser extent in immunocompromised hosts. (duke.edu)
  • We used " Cryptococcus gattii " and "China (or specific location)" to search all related publications in PubMed and China National Knowledge Infrastructure (CNKI). (researchsquare.com)
  • Search Cryptococcus neoformans var. (ensembl.org)
  • The genome of Cryptococcus neoformans JEC21 (serotype D) was not sequenced by the JGI, but by TIGR. (doe.gov)