We have employed this technique on 109 patients with conjunctival squamous neoplasms and 137 patients with conjunctival melanoma, about 80 of which neoplasms were associated with primary acquired melanosis. (nih.gov)
Our observations suggest that well-planned initial surgical management using this technique decreases the chance of tumor recurrence for conjunctival melanoma and squamous cell carcinoma. (nih.gov)
To illustrate a novel method of management for extensive conjunctival and corneal melanoma. (nih.gov)
A 40-year-old Caucasian woman presented with a large, diffuse conjunctival melanoma involving 6 clock hours of the limbus. (nih.gov)
The conjunctival melanoma was completely resected microsurgically in one piece without disrupting the tumor. (nih.gov)
Preliminary evidence suggests that combined therapeutic approaches, consisting of extensive tumor removal, cryotherapy, amniotic membrane allograft, and topical mitomyin C, can be effective in the management of diffuse conjunctival and corneal melanoma arising from primary acquired melanosis. (nih.gov)
Scholars@Duke publication: Advances in the management of conjunctival melanoma. (duke.edu)
Long term follow-up of patients with conjunctival melanoma with systemic surveillance is necessary to detect recurrences and metastases. (duke.edu)
There have been particularly substantial changes to the classification of conjunctival neoplasia and melanoma, based on the latest information from genetic and molecular studies. (iarc.fr)
4. What is the most common location for conjunctival melanoma? (surajeyeinstitute.org)
5. Which architectural pattern is a clue to the diagnosis of conjunctival melanoma? (surajeyeinstitute.org)
Explanation: The most common location for conjunctival melanoma is the bulbar conjunctiva close to the limbus. (surajeyeinstitute.org)
Management of conjunctival malignant melanoma: a review and update. (surajeyeinstitute.org)
Explanation: Presence of intraepithelial nests, cyst formation, and maturation with depth are not specific architectural clues for conjunctival melanoma, while the presence of pagetoid growth is a pattern suggestive of conjunctival melanoma. (surajeyeinstitute.org)
The most useful architectural patterns suggestive of conjunctival melanoma include (1) intraepithelial component showing pagetoid growth (2) radial extension of the intraepithelial component beyond the lateral edge of subepithelial component, (3) patchy or bandlike inflammation at the base of the lesion, (4) mitotic activity, (5) lack of maturation toward the base of the lesion, (6) invasion of the sclera or cornea. (surajeyeinstitute.org)
Conjunctiva7
The extensive conjunctival defect, involving one-half of the bulbar conjunctiva, was reconstructed with an amniotic membrane allograft. (nih.gov)
Conclusions FISH is very useful in classifying equivocal conjunctival melanocytic lesions, especially those with atypical junctional activity and naevoid melanocytic proliferations of the conjunctiva. (bmj.com)
Sections are included on all recognized neoplasms (and their variants) of the eye, lacrimal apparatus, and conjunctiva. (iarc.fr)
Explanation: melanocytic naevi are the most common tumors of the conjunctiva, accounting for up to 28% of all conjunctival neoplasms. (surajeyeinstitute.org)
and 4) the thin and flexible palpebral conjunctiva, which continues to the conjunctival fornix or conjunctival cul-de-sac. (merckvetmanual.com)
[2] Conjunctival lesions present as a localized yellow nodule on the bulbar conjunctiva (Figure 3). (eyewiki.org)
Additionally it is regarded the most frequent neoplasm from the conjunctiva, normally affecting elderly men of around 70?years [3,4]. (antiviralbiologic.com)
Tumors3
Specifically, conjunctival papillomas are benign squamous epithelial tumors with a minimal propensity toward malignancy. (medscape.com)
Surgical management of conjunctival tumors. (nih.gov)
To our knowledge, there are no articles that describe the specific step-by-step details of the surgical removal of premalignant and malignant conjunctival tumors. (nih.gov)
Carcinoma3
Several cases of locally advanced conjunctival, eyelid, and lacrimal sac/duct squamous cell carcinoma that were successfully treated with immune checkpoint inhibitors (PD-1 directed) are shared. (bvsalud.org)
Parallel studies by Waddell and colleagues also suggested that HIV contamination is strongly associated with an increase in the incidence of conjunctival carcinoma in Africa [10]. (antiviralbiologic.com)
Sebaceous carcinoma is a malignant neoplasm arising in sebaceous glands that is characterized by extensive lipid production. (missionforvisionusa.org)
Lesions4
Although rare, inverted conjunctival papillomas sometimes are referred to as mucoepidermoid papillomas because these lesions possess both a mucous component and an epidermoid component. (medscape.com)
It is useful as a guide for where to obtain a biopsy specimen or resect ill-defined conjunctival lesions. (medscape.com)
Follow-up Examinations for Occular Neoplasms and Pigmented Ocular Lesions, at the Dupont, West Virginia Plant. (cdc.gov)
Active and retired workers at the duPont Belle chemicals facility in West Virginia were ophthalmologically surveyed first in 1978 and again in 1979 in a follow-up study to identify cases of ocular neoplasms and determine the prevalence of ocular pigmented lesions. (cdc.gov)
Tumor3
Eye neoplasms can affect all parts of the eye, and can be a benign tumor or a malignant tumor (cancer). (wikipedia.org)
1. What is the most common type of tumor among conjunctival neoplasms? (surajeyeinstitute.org)
It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
Lymphoma6
Results -Animals with intraocular (4 dogs and 1 cat) or conjunctival (3 dogs and 1 cat) lymphoma represented 0.1% and 0.08% of patients with lymphoma evaluated at the hospital during the study period, respectively. (avma.org)
animals with conjunctival lymphoma represented 0.16% of all patients with conjunctivitis. (avma.org)
Lymph node metastasis was detected in 2 patients with conjunctival lymphoma. (avma.org)
Median PFST and OST for animals with conjunctival lymphoma were 221 and 549 days, respectively. (avma.org)
To date, the clinical features of the various subtypes of conjunctival lymphoma (CL) have not been previously evaluated in a large cohort. (liverpool.ac.uk)
Conjunctival lymphoma consists of mainly 4 subtypes of B-cell non-Hodgkin lymphoma: EMZL, FL, MCL, and DLBCL. (liverpool.ac.uk)
Management of conjuncti1
We describe a detailed stepwise approach to the surgical management of conjunctival neoplasms. (nih.gov)
Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. (lookformedical.com)
Treatment of conjunctival2
Topical timolol for the treatment of conjunctival pyogenic granulomas: Outcomes and effect on intraocular pressure. (nih.gov)
METHODOLOGY: Patients who underwent excision for the diagnosis and treatment of conjunctival surface masses with clinical suspicion of malignancy were evaluated retrospectively. (bvsalud.org)
Cytology1
Irrelevant of its cytology, a neoplasm of epithelial origin with this form of growth is also called papilloma. (medscape.com)
Conjunctivitis1
Pterygium mimics include localized conjunctival neoplasia, conjunctivitis, and episcleritis. (mhmedical.com)
Epithelial cells do not demonstrate atypia, and dysplastic changes are uncommon for conjunctival inverted papillomas. (medscape.com)
A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
Neoplasia1
Overview of Neoplasia of the Eye and Associated Structures in Animals The various tissues of the eye and associated structures can be the site of primary or metastatic neoplasms. (merckvetmanual.com)
Diagnosis1
In skin pathology, the recent application of fluorescence in situ hybridisation (FISH) has been demonstrated to be of use for the analysis and diagnosis of ambiguous melanocytic neoplasms of the skin. (bmj.com)
Histologically2
This study set out to evaluate this method on seven prospective conjunctival cases that were histologically equivocal. (bmj.com)
The neoplasms may be histologically the same or different, and may be found in the same or different sites. (lookformedical.com)
Papilloma7
Conjunctival papilloma also can be classified based on gross clinical appearance, as either pedunculated or sessile. (medscape.com)
The pedunculated type is synonymous with infectious conjunctival papilloma and squamous cell papilloma. (medscape.com)
The limbal conjunctival papilloma often is referred to as noninfectious conjunctival papilloma because it is believed that limbal papillomas arise from UV radiation exposure. (medscape.com)
HPV type 11 was the most common and frequently found in conjunctival papilloma as analyzed by polymerase chain reaction (PCR). (medscape.com)
HPV types 6 and 11 are the most frequently found in conjunctival papilloma. (medscape.com)
HPV type 33 is another source in the pathogenesis of conjunctival papilloma. (medscape.com)
Squamous cell papillomas (eg, infectious papilloma, viral conjunctival papilloma) are composed of multiple branching fronds emanating from a narrow pedunculated base. (medscape.com)
Confocal1
Finally, confocal microscopy provides en-face images of the ocular surface, with OSSN showing a classic 'starry night' appearance. (avehjournal.org)
Disease1
RESULTS Of the 112 leopard geckos, 52 (46%) had ophthalmic disease (mainly corneal or conjunctival disease). (avma.org)
Moreover, the HPV genome is identifiable in most conjunctival papillomas and in 85% of conjunctival dysplasias and carcinomas. (medscape.com)
Nevi1
The prevalence of participants with conjunctival nevi, iris nevi, and chordal nevi amounted to 0.9 and and nonindustrial workers, respectively. (cdc.gov)
Solitary1
Solitary conjunctival hemangioma presenting as a chocolate cyst. (nih.gov)
Tissue3
It appears as a light brown or yellow-white amorphous, slightly raised conjunctival tissue adjacent to the limbus. (mhmedical.com)
A small area of yellowish "heaped up" conjunctival tissue is seen adjacent to the nasal limbus. (mhmedical.com)
Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
Prevalence1
The literature reviewed yielded no published study outlining the prevalence of conjunctival papillomas in a cross-section of a population. (medscape.com)
Infectious1
Infectious conjunctival papillomas also are known as squamous cell papillomas. (medscape.com)
Examination1
OBJECTIVE: To evaluate the histopathological results of conjunctival masses suspected to be malignant based on biomicroscopic examination. (bvsalud.org)
Cytoplasm1
In the higher magnification image, the malignant neoplasm features large cells with vesicular bubbly cytoplasm (arrow 6). (missionforvisionusa.org)