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  • oxaloacetate
  • Two binding sites can be found therein: one reserved for citrate or oxaloacetate and the other for Coenzyme A. The active site contains three key residues: His274, His320, and Asp375 that are highly selective in their interactions with substrates. (wikipedia.org)
  • anticoagulant
  • In 1914, the Belgian doctor Albert Hustin and the Argentine physician and researcher Luis Agote successfully used sodium citrate as an anticoagulant in blood transfusions, with Richard Lewisohn determining its correct concentration in 1915. (wikipedia.org)
  • anions
  • The crystal structure comprises a three-dimensional network in which eightfold coordinated Ca2+ cations are linked by citrate anions and hydrogen bonds between two non-coordinating crystal water molecules and two coordinating water molecules. (wikipedia.org)
  • Sometimes the term is also used for the salt tetraferric tricitrate Fe 4(C 6H 4O 7)3, where the citrate anions are fully deprotonated (C 6H 4O4− 7). (wikipedia.org)
  • organism
  • The citrate test detects the ability of an organism to use citrate as the sole source of carbon and energy. (wikipedia.org)
  • Bacterial colonies are picked up from a straight wire and inoculated into slope of Simmons citrate agar and incubated overnight at 37 °C. If the organism has the ability to use citrate, the medium changes its color from green to blue. (wikipedia.org)
  • discomfort
  • Sodium citrate is used to relieve discomfort in urinary tract infections, such as cystitis, to reduce the acidosis seen in distal renal tubular acidosis, and can also be used as an osmotic laxative. (wikipedia.org)
  • name
  • Caffeine citrate, sold under the trade name Cafcit among others, is a medication used to treat a lack of breathing in premature babies. (wikipedia.org)
  • The name comes for apocholate and citrate in agar. (wikipedia.org)
  • patients
  • Julia B. Lewis, Mohammed Sika, Mark J. Koury, and others (2015): "Ferric Citrate Controls Phosphorus and Delivers Iron in Patients on Dialysis", Journal of the American Society of Nephrology, volume 26, issue 2, pages 493-503. (wikipedia.org)
  • mainly
  • These alpha helices compose approximately 75% of citrate synthase's tertiary structure , while the remaining residues mainly compose irregular extensions of the structure, save a single beta-sheet of 13 residues. (wikipedia.org)