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  • locus
  • The selected Xi becomes the target of a chromosome‐wide mechanism of transcriptional silencing, which constitutes an exciting paradigm for epigenetic regulations and confirms interest in the molecular dissection of the X‐inactivation centre ( Xic ), a locus on the X chromosome that contains the Xist gene and the elements involved in counting, choice and silencing. (embopress.org)
  • AMONG species with genetic sex determination, sex is determined in the vast majority by a single locus or chromosome ( B ull 1983 ). (genetics.org)
  • male
  • X chromosome inactivation (XCI), which occurs only in female (XX) and not in male (XY) embryos, ensures dosage compensation of X‐linked genes between the sexes. (embopress.org)
  • Xist is expressed at very low levels from every X chromosome in both undifferentiated male and female ES cells. (embopress.org)
  • pairs
  • These species have typical avian karyotypes that consist of several pairs of relatively large macrochromosomes (chromosomes 1-10 and a pair of sex chromosomes, ZW in females and ZZ in males) and numerous tiny microchromosomes. (springer.com)
  • The entire gene spans 5568 base pairs on the positive strand of chromosome 5 (140019113-140024689bp) but is alternately spliced into different variants. (wikipedia.org)
  • nucleus
  • 2005: Maffo Vialli International Award for Histochemistry for pioneering contributions to the study of higher order chromatin arrangement through laser-UV microirradiation and fluorescence based molecuar cytogenetics 2009: Award of the Schleiden Medal of the German Academy of Sciences Leopoldina for his distinguished scientific work on nuclear architecture with special focus on the topography of chromosomes in the nucleus. (wikipedia.org)
  • chicken
  • Immunostaining for cohesin followed by FISH with 23 BAC clones, covering the region from 0 to 23 Mb on chicken chromosome 3 (GGA3), allowed us to map the GGA3 centromere between BAC clones WAG38P15 and WAG54M22 located at position 2.3 and 2.5 Mb, respectively. (wur.nl)
  • Furthermore, we have determined that the current putative centromeric gap at position 11.6-13.1 Mb corresponds in fact to a long cluster of tandem chicken erythrocyte nuclear membrane repeats (CNM). (wur.nl)
  • Despite the newly identified and confirmed inversions, our data suggest that, in chicken and Japanese quail, the difference in centromere positions is not mainly caused by pericentric inversions but is instead due to centromere repositioning events and the formation of new centromeres. (springer.com)
  • adjacent
  • Our work suggests that H-NS is involved in condensing the DNA along adjacent segments on the chromosome and is not likely to tether newly replicated strands of sister DNA. (asm.org)
  • Dosage
  • The nematode Caenorhabditis elegans possesses a third complex (closely related to condensin I) that participates in chromosome-wide gene regulation, i.e., dosage compensation. (wikipedia.org)
  • cell
  • In H-NS mutant cells, foci of SeqA, replisomes, and origins were irregularly positioned in the cell. (asm.org)
  • region
  • Cis acting elements refer to mechanisms that act on the same chromosome they come from, usually either in the same region from which they were produced or a region very close to this origin region. (wikipedia.org)
  • However
  • However, the similarity in reaction observed when looking at chromosomes carrying similar changes suggests a direct causal relation between induced change and observed reaction. (biomedcentral.com)
  • Recent data, however, finds that aspects of the 'force balance' model that posit spindle length and stability to be mediated by a balance between the minus-end directed microtubule sliding and plus-end directed microtubule sliding by opposing motors in insect cells, seems not to be the case in mammalian cells. (wikipedia.org)
  • assembly
  • This corresponds to the gap between 2 supercontigs at the 2.4-Mb position in the current GGA3 sequence assembly (build 2.1). (wur.nl)
  • During prometaphase and metaphase, both condensin I and condensin II contribute to the assembly of condensed chromosomes, in which two sister chromatids are fully resolved. (wikipedia.org)
  • sites
  • The architectural protein H-NS binds nonspecifically to hundreds of sites throughout the chromosome and can multimerize to stiffen segments of DNA as well as to form DNA-protein-DNA bridges. (asm.org)
  • cells
  • In this study, we investigated the positioning and dynamics of the origins, the replisomes, and the SeqA structures trailing the replication forks in cells lacking the H-NS protein. (asm.org)
  • local
  • At some positions, expression was more than 3-fold higher than at the natural lac promoter locus, whereas at several other locations, the reporter cassette was completely silenced: effectively overriding local lac promoter control. (sparrho.com)
  • current
  • The increasing knowledge in this area offers the possibility of exercising a degree of control over CO positioning or -frequency which holds the promise of speeding up current breeding programs. (biomedcentral.com)
  • locus
  • The selected Xi becomes the target of a chromosome‐wide mechanism of transcriptional silencing, which constitutes an exciting paradigm for epigenetic regulations and confirms interest in the molecular dissection of the X‐inactivation centre ( Xic ), a locus on the X chromosome that contains the Xist gene and the elements involved in counting, choice and silencing. (embopress.org)
  • AMONG species with genetic sex determination, sex is determined in the vast majority by a single locus or chromosome ( B ull 1983 ). (genetics.org)
  • male
  • X chromosome inactivation (XCI), which occurs only in female (XX) and not in male (XY) embryos, ensures dosage compensation of X‐linked genes between the sexes. (embopress.org)
  • Xist is expressed at very low levels from every X chromosome in both undifferentiated male and female ES cells. (embopress.org)
  • early
  • Escherichia coli cells depleted of the conserved GTPase, ObgE, show early chromosome-partitioning defects and accumulate replicated chromosomes in which the terminus regions are colocalized. (wiley.com)
  • mtDNA
  • The ancient migration patterns are reflected in the clear north-south gradients in several palaeolithic and neolithic haplogroups in the mtDNA (U5, I, K, T, X) and the Y chromosome (R1b, N3). (blogspot.com)
  • On the edge of the Bantu expansions: patterns of mtDNA and Y-chromosome variation in southwestern Angola. (blogspot.com)
  • To address this issue, we have analyzed the mitochondrial DNA (mtDNA) of 185 individuals and NRY (non-recombining region of Y chromosome) of 98 individuals belonging to two major tribal populations of Maharashtra, and compared their molecular variations with that of 54 South Asian contemporary populations of adjacent states. (blogspot.com)
  • markers
  • To resolve the issue, we screened 621 Y-chromosomes (of Brahmins, occupying upper most caste position and Dalits and Tribals with the lower most positions in the Indian caste hierarchical system) with fifty-five Y-chromosomal binary markers and Y-microsatellite markers and compiled a data set of 2809 Y-chromosomes (681 Brahmins, 2128 Tribals and Dalits) for conclusions. (blogspot.com)
  • sequence
  • It appears that dots represent identity with the reference sequence, so for example M201 has a dot for skeleton 1 which indicates a T at position 15,027,529 (GRCh37) which is the position where this mutation has occurred. (blogspot.com)
  • The computational analysis of an RNA-Seq experiment begins earlier: what we get from the sequencing machine is a set of FASTQ files that contain the nucleotide sequence of each read and a quality score at each position. (bioconductor.org)
  • The concept of the formation arose in the 18th century to designate large strata of sedimentary rocks identified by the predominance of certain rock types or combination of types and by position in the general sequence of geological bedding, for example, chalk and the Old Red Sandstone in Europe. (thefreedictionary.com)
  • cause
  • Other changes in the number or structure of chromosome 7 can cause delayed growth and development, mental disorder, characteristic facial features, skeletal abnormalities, delayed speech, and other medical problems. (wikipedia.org)