• meiosis
  • We have developed a yeast model system in which each yeast cell has one pair of non-recombined partners in every meiosis. (omrf.org)
  • mechanism
  • The mechanism by which specific regions of the chromosome are organized and segregated prior to division remains a mystery. (wiley.com)
  • We recently provided evidence from immunofluorescence and electron microscopy studies that merotelic kinetochore orientation is a major mechanism for lagging chromosomes during mitosis in PtK1 cells. (biologists.org)
  • The selected Xi becomes the target of a chromosome‐wide mechanism of transcriptional silencing, which constitutes an exciting paradigm for epigenetic regulations and confirms interest in the molecular dissection of the X‐inactivation centre ( Xic ), a locus on the X chromosome that contains the Xist gene and the elements involved in counting, choice and silencing. (embopress.org)
  • appear
  • Most likely this suppression was the result of a series of chromosomal inversions on the Y chromosome, which would also explain why the genes appear to be in order on the X but scrambled on the Y," Page explains. (abc.net.au)
  • found
  • Researchers at the Howard Hughes Medical Institute have found that the X and Y chromosomes evolved from a standard identical pair around 300 million years ago - shortly after the divergence of the evolutionary lines leading to mammals and birds. (abc.net.au)
  • The X chromosome was found to have four groups of genes physically arranged as four consecutive blocks, like the layers of rock in geological strata. (abc.net.au)
  • random
  • Furthermore, the lagging of pairs of separated sisters was higher than expected from random chance indicating that merotelic orientation of one sister may promote merotelic orientation of the other. (biologists.org)
  • Science
  • Research published in this week's Science reveals that the Y chromosome developed from an X-like ancestor around 300 million years ago. (abc.net.au)
  • model
  • Our projects primarily use the yeast, Saccharomyces cerevisiae, as a model to elucidate conserved aspects of eukaryotic chromosome biology. (omrf.org)