• genetic
  • The results did not show an increased rate of later aberrations indicative of genetic instability. (rerf.jp)
  • Statistical analysis will be performed to ascertain the association between occupational exposure to antineoplastic drugs and biomarkers of DNA and chromosome damage, after taking into account the effects of individual genetic susceptibility, and the presence of confounding exposures. (biomedcentral.com)
  • The project is directed by Daniela S. Gerhard, and includes sub-projects or initiatives, with notable ones including the Cancer Chromosome Aberration Project (CCAP) and the Genetic Annotation Initiative (GAI). (wikipedia.org)
  • Cancer
  • A recent review noted that "It was first published in 1983 as a book named "The Catalog of Chromosome Aberrations in Cancer", containing 3,844 cases. (wikipedia.org)
  • The aim is to assess in hospital nurses preparing and/or administering therapy to cancer patients the current level of occupational exposure to antineoplastic drugs, DNA and chromosome damage as cancer predictive effects, and the association between the two. (biomedcentral.com)
  • 21)), and TMPRSS2-ERG with an interstitial deletion on chromosome 21, often occurring in prostate cancer. (wikipedia.org)
  • This suggest that the rearrangements took place at a time that both parental copies of the chromosome were present and hence early on the development of the cancer cell. (wikipedia.org)
  • 1985
  • In 1985 it was clearly established that the fusion gene on chromosome 22 produced an abnormal chimeric BCR/ABL1 protein with the capacity to induce chronic myeloid leukemia. (wikipedia.org)
  • dose
  • The small but consistent differences between the two cities may be due either to different scoring efficiency of aberrations in the two laboratories or to differential errors in DS86 dose assignments. (rerf.jp)
  • Syndrome
  • In 2015, it was found that chromothripsis can also be curative: a woman who had WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome, an extremely rare autosomal dominant combined immunodeficiency disease, found her symptoms disappeared during her 30s after chromothripsis of chromosome 2 deleted the disease allele. (wikipedia.org)
  • Data
  • Ahmed does on the fine features of Ophthalmology, the Journal of Cataract and Refractive Surgery, and Techniques in Ophthalmology, among years, and he welcomes a download Chromosome for strong data as effortlessly. (leadroof.org.uk)
  • Results
  • This results in parts of the chromatids or chromosomes being broken off and enveloped as an extra nucleus in one of the daughter cells. (wikipedia.org)
  • risk
  • No increased risk for AML with complex CCA or with total or partial losses of chromosomes 5 or 7 were observed, but a higher risk was found for AML with trisomy 8 (OR 11, 95% CI 2.7-42) as the sole aberration. (sjweh.fi)
  • specific
  • Based on these lines, 88 markers specific for chromosome 2R were physically mapped to 13 different blocks of 2R with three in arm 2RS and 10 in arm 2RL. (springer.com)