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  • spindle
  • Therefore, if by chance a microtubule exploring the center of the cell encounters a kinetochore, it may happen that the kinetochore will capture it, so that the chromosome will become attached to the spindle via the kinetochore of one of its sister chromatids. (wikipedia.org)
  • It senses tension between sister chromatids during mitosis, and it degrades when they separate preventing cell cycle arrest and chromosome loss.Human shugoshin is diffusible and mediates formation of kinetochore-microtubules during bipolar spindle assembly. (wikipedia.org)
  • In cell biology, the spindle apparatus (or mitotic spindle) refers to the cytoskeletal structure of eukaryotic cells that forms during cell division to separate sister chromatids between daughter cells. (wikipedia.org)
  • Mitotic
  • Regarding mitotic chromosome structure, centromeres represent a constricted region of the chromosome (often referred to as the primary constriction) where two identical sister chromatids are most closely in contact. (wikipedia.org)
  • alleles
  • Then sister chromatids are EXACTLY alike with position and their alleles. (studentdoctor.net)
  • Sister chromatids are by and large identical (since they carry the same alleles, also called variants or versions, of genes) because they derive from one original chromosome. (wikipedia.org)
  • If the chromatids containing different alleles line up on the same side of the plate, then the resulting daughter cells will appear heterozygous and be undetectable, despite the crossover event. (wikipedia.org)
  • However, if chromatids containing the same alleles line up on the same side, the daughter cells will be homozygous at that locus. (wikipedia.org)
  • cell
  • Sometimes sister chromatids do not separate during cell division, leading to a situation known as nondisjunction where one daughter cell lacks the chromosome while the other gets both copies of it. (wikipedia.org)