ProliferationCellular ProcessesVitroTumourElongationFibroblast GrowthProteinMammalianReceptorBiological processesGenes involved in cell adhesionPathwayApoptosisProteinsMutationsSignalsBacterial growthBiopharmaceutical productsBasalDetachmentProliferate2023InduceNutrientsMicrobial cellsTissuesEpithelialReceptorsProgressionAdhesionMetabolismVaccineInhibitorsTumor formationAbnormal cellsVaccinesDifferentiationVarious cellularEpidermalBlood vesselsInflammatory cellsHormonesSynthesisSurvivalExponentialFactorsNasalRegulate2016RegulationSemiconductor thin filmsImmuneSubstrateDegradationMolecularInhibitSkeletalDownstreamInsulinSolar cellsMicroorganismsSubsequentActinSomaticCarcinogensRateCancer cells
Proliferation9
- Integrins are key regulators of gene expression, cell proliferation and migration. (europa.eu)
- This serum-free and grain-derived-nutrient-free medium promoted the proliferation of bovine myoblasts, the main cell source for cultured beef. (nature.com)
- EGFR methylation sustained signaling activity and cell proliferation even in the presence of cetuximab," said Hung. (sciencedaily.com)
- The colonic mucosa is a self-renewing epithelium that is structured is a very tightly regulated balance between cell proliferation at the base of a crypt, maturation as colonocytes, migrate up the crypt, and extrusion of senescent and/or apoptotic cells from the upper crypt into the lumen. (medscape.com)
- Upon further investigations, the team tested the STAT3 inhibitors - a substance and member of the STAT family that interferes with biologic activity including growth and proliferation - and discovered that these inhibitors killed lymphoma cells with DDX3X mutation (or altered DDX3X) more effectively than standard chemotherapy agents. (eurekalert.org)
- In addition, their osteogenic differentiation potential was increased, and genes involved in cell adhesion, FGF-2 signalling, cell cycle, stemness, cell differentiation, and cell proliferation were upregulated, compared to that of the MSCs cultured on uncoated plates. (hindawi.com)
- The errors disrupt other genes involved in important cellular processes, such as controlling cell growth and division (proliferation). (medlineplus.gov)
- Results and Conclusions: The adaptation process was characterized by initial cell population growth arrest, and after that extensive cell death, followed by proliferation and long-term survival of clonal cultures. (lu.se)
- Proliferation and cell cycle progression of the serum-free cultures closely mimicked that of serum-dependent cells. (lu.se)
Cellular Processes3
- It will also provide an introduction into how understanding basic cellular processes can be used to understand the mechanisms by which antibiotics specifically inhibit certain bacteria and permit the identification of new targets for the development of novel antibiotics. (ncl.ac.uk)
- This signaling pathway regulates various cellular processes and is involved in the growth of cells. (medlineplus.gov)
- While results from mouse cells may not mirror cellular processes in humans , it is believed that the 145 height genes could be used in clinical settings to help find treatments for patients with skeletal dysplasia and other skeletal disorders. (medscape.com)
Vitro8
- Cultured meat is produced by culturing/proliferating animal muscle cells in vitro. (nature.com)
- The treatments involved a personalised preparation of the drug candidate using the dendritic cells, taken from the patient and manufactured by Sotio in vitro in large quantities. (outsourcing-pharma.com)
- RNA, in vitro protein production, and cell therapies). (bioprocessintl.com)
- However, MSCs need to be expanded in vitro in order to obtain sufficient cells for clinical trials since they are extremely rare in various tissues. (hindawi.com)
- Unlike embryonic stem cells, adult stem cells (MSCs) have a limited lifespan and stop proliferating during in vitro culture due to replicative senescence [ 8 ]. (hindawi.com)
- Results: LED produced in vitro increases of cell growth of 140-200% in mouse-derived fibroblasts, rat-derived osteoblasts, and rat-derived skeletal muscle cells, and increases in growth of 155-171% of normal human epithelial cells. (researchgate.net)
- In vitro studies using infra-/red light have not shown any useful impact on wound healing by activating cells located in deeper skin layers such as fibroblasts or stem cells [2] . (researchgate.net)
- Objective: Serum is usually added to growth media when mammalian cells are cultured in vitro to supply the cells with growth factors, hormones, nutrients and trace elements. (lu.se)
Tumour11
- Caveolin-1 regulates anchorage-dependent growth and is a tumour suppressor. (europa.eu)
- These results may provide a molecular explanation for the role of caveolin-1 as tumour suppressor and provide insight into the mechanism of anchorage-independent growth, one of the hallmarks of cancer. (europa.eu)
- nasal tumour, abnormal growth in the nose. (britannica.com)
- Based in Prague, Czech Republic, Sotio is developing personalised dendritic cell vaccines (DCVACs) based on dendritic cells cultivated from a patient's blood monocytes and used to induce an immune response against tumour cells. (outsourcing-pharma.com)
- Tumour cells (from cancer cell lines) killed by High Hydrostatic Pressure (HHP) are engulfed in these dendritic cells, before being reintroduced into the patient's body in the form of immunotherapeutic vaccine to trigger the required response from the patient's immune system against the harmful tumour cells. (outsourcing-pharma.com)
- The company says the dendritic cells pulsed with the dead tumour cells have an increased ability to induce cytotoxic T cell responses, which increases the probability of inducing efficient immune response in the body. (outsourcing-pharma.com)
- It was also shown that inhibition of the p16 tumour suppressor gene delays growth arrest and therefore senescence of MSC [ 16 ]. (hindawi.com)
- This puts pressure in the growing tumour, as cancerous cells are amongst those dying, a common solution must be developed to supply nutrients. (scientificamerican.com)
- The cell death, largely due to hypoxia induces angiogenesis which restores a supply of nutrients and facilitates further tumour growth. (scientificamerican.com)
- With a newly established nutrient supply the cancerous tumour can continue to grow but eventually the tumour will become so large that the centre of the tumour is too far from a blood vessel to be provided with nutrients and then the cells at the centre of these tumours must die. (scientificamerican.com)
- Furthermore, preclinical models of Wilms tumour, from cell lines to organoid cultures, have evolved. (bvsalud.org)
Elongation3
- Here, we combined computational modeling with quantitative cell physiology to understand the dynamics of the plasma membrane (PM)-localized BR response pathway during the initiation of cellular responses in the epidermis of the Arabidopsis root tip that are be linked to cell elongation. (elifesciences.org)
- Thus, we established the landscape of components and parameters for physiological processes potentially linked to cell elongation, a central process in plant development. (elifesciences.org)
- We observe that the processes form by elongation as well as the previously reported retraction of cytoplasm around cytoskeletal elements. (rupress.org)
Fibroblast Growth2
- We have tested simultaneous inhibition of vascular endothelial growth factor, fibroblast growth factor, and platelet-derived growth factor receptor signaling by novel indolinone derivatives using 14 myeloid, including 11 human leukemic, cell lines. (nih.gov)
- Any process that activates or increases the frequency, rate or extent of cell chemotaxis to fibroblast growth factor. (mcw.edu)
Protein8
- Since furin converts many growth-related protein precursors to their bioactive forms, we compared the four pancreatic islet cell lines RINm5F, βTC3, βHC9, and MIN6 with respect to cell growth rate, furin expression, endoprotease activity, and insulin content. (diabetesjournals.org)
- We also found that dBcAMP and ML-9 both cause a decrease in the phosphate content of actin depolymerizing factor, suggesting that this protein and myosin light chain are the effectors of actin cytoskeleton reorganization and process growth. (rupress.org)
- Compared to grains, microalgae have higher growth capacity and usable protein content in their biomass. (nature.com)
- The study showed that EGFR methylation was mediated by PRMT1, a protein involved in a variety of genetic processes including gene transcription, DNA repair and signaling. (sciencedaily.com)
- They found that mutations in the gene DDX3X - a type of protein responsible for processing and transmitting signals for cell growth - is the possible culprit behind cancer cells' resilience. (eurekalert.org)
- The SAP49 protein is particularly important for the maturation of cells that build bones and cartilage (osteoblasts and chondrocytes). (medlineplus.gov)
- Although the effect of this protein shortage is unknown, researchers suspect that it disrupts spliceosome formation, which may impair mRNA processing and alter the activity of genes involved in the development of several parts of the body. (medlineplus.gov)
- This protein helps fix errors that are made when DNA is copied (DNA replication) in preparation for cell division. (medlineplus.gov)
Mammalian1
Receptor4
- In acute myeloid leukemia (AML), receptor tyrosine kinase ligands promote growth and survival and contribute to AML-associated marrow neoangiogenesis. (nih.gov)
- In healthy blood vessels, the cells that line the blood vessels do not possess the p75NTR receptor, and the development of new blood vessels and healing of the obstructed blood supply and wounds is rapid. (eurekalert.org)
- However, diabetes causes the cells lining the blood vessels to produce the p75NTR receptor, and prevents the growth of new blood vessels necessary for blood supply and healing of damaged tissue. (eurekalert.org)
- Dr Emanueli's group found that if they put the receptor gene into healthy blood vessel cells, the cells became dysfunctional. (eurekalert.org)
Biological processes1
- Arnold tongues are observed in a large variety of natural phenomena that involve oscillating quantities, such as concentration of enzymes and substrates in biological processes and cardiac electric waves. (wikipedia.org)
Genes involved in cell adhesion1
- Two major thrusts in the last decade have dramatically impacted our understanding of biofilms: the utilization of the confocal laser scanning microscope to characterize biofilm ultrastructure, and an investigation of the genes involved in cell adhesion and biofilm formation. (cdc.gov)
Pathway2
- Taken together, our data suggest that PI3K may represent an important step in the LPA signal transduction pathway responsible for ROS generation and DNA synthesis in RASM cells. (mcw.edu)
- We show that maximal growth is achieved when pathway activation is a more or less steeply graded function of the nutrient concentration. (lu.se)
Apoptosis2
- Furthermore, both compounds induced apoptosis in the sensitive cell lines. (nih.gov)
- Most changes were subtle, but frequently the genes with altered expression were involved in basal cellular functions such as cell division, cell cycle regulation, apoptosis and cell signalling. (lu.se)
Proteins6
- New research reveals insight into how key proteins, known as epidermal growth factor receptors (EGFR), are regulated, leading to resistance. (sciencedaily.com)
- The results, published in the Nov. 16 online issue of the Journal of Clinical Investigation reveal new insight into how key proteins, known as epidermal growth factor receptors (EGFR), are regulated, leading to resistance. (sciencedaily.com)
- Methylation is a process by which proteins are chemically altered. (sciencedaily.com)
- Akts are proteins known as kinases that regulate cell signaling. (mdanderson.org)
- Spliceosomes help process messenger RNA (mRNA), which is a chemical cousin of DNA that serves as a genetic blueprint for making proteins. (medlineplus.gov)
- Defined proteins and metal ions, such as insulin, growth factors, transferrin and sodium selenite, are sometimes also included and can in some cases substitute serum components. (lu.se)
Mutations5
- They also found that DDX3X mutations cause increased STAT activity - a type of signalling mechanism that allows cancer cells to survive. (eurekalert.org)
- Asst Prof Navin said, "Now that we know DDX3X mutations are what make some cancer cells difficult to kill with chemotherapy, it is possible to identify patients with such mutations through lab tests before treatment starts. (eurekalert.org)
- When caused by mutations in the SF3B4 gene, Nager syndrome follows an autosomal dominant inheritance pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. (medlineplus.gov)
- which means both copies of a gene in each cell have mutations. (medlineplus.gov)
- This production technology has some drawbacks including the fact that growth in eggs can cause mutations in the vaccine viruses that can impact how well the vaccines work. (cdc.gov)
Signals3
- Integrin signals mediate anchorage-dependence of cell growth, while growth of cancer cells is anchorage-independent. (europa.eu)
- Located on the X chromosome, the gene DDX3X processes cell information and transmits signals for cell growth. (eurekalert.org)
- Angiogenesis is the direct growth of blood vessels and requires the presence of hypoxic cells and angiogenic signals. (scientificamerican.com)
Bacterial growth2
- The objective being to give an overview of the methods used in the discovery of molecular mechanisms used by model bacteria and the application of this in understanding the basic processes involved in bacterial growth and development in terms of regulation and biological function. (ncl.ac.uk)
- Heukelekian and Heller ( 1 ) observed the "bottle effect" for marine microorganisms, i.e., bacterial growth and activity were substantially enhanced by the incorporation of a surface to which these organisms could attach. (cdc.gov)
Biopharmaceutical products2
- This high growth is attributed to the need for highly pure biopharmaceutical products to meet the regulatory standards, as downstream purification plays a significant role in enhancing the purity and quality of products aiding the growth of the purification market. (marketsandmarkets.com)
- Furthermore, pDNA is used as a master-template product to support production of new and emerging biopharmaceutical products and processes (e.g. (bioprocessintl.com)
Basal2
- Animal cells are generally cultured in basal media supplemented with fetal bovine serum (FBS) which provides the various factors essential for cell growth. (nature.com)
- New devices have demonstrated significant results for the treatment of medical conditions, including mild-to-moderate acne vulgaris, wound healing, psoriasis, squamous cell carcinoma in situ (Bowen's disease), basal cell carcinoma, actinic keratosis, and cosmetic applications. (researchgate.net)
Detachment3
- Integrin-mediated retention of phosphorylated caveolin in focal adhesions inhibits raft internalisation, which occurs upon its recruitment to caveolae after cell detachment. (europa.eu)
- Angiogenesis begins with perivascular detachment and vessel dilation (b), followed by angiogenic sprouting (c), new vessel formation and maturation, and the recruitment of perivascular cells (d). (scientificamerican.com)
- Cells may also communicate via quorum sensing, which may in turn affect biofilm processes such as detachment. (cdc.gov)
Proliferate2
- We hypothesized that by selecting optimal animal cells and using their CM to culture animal myoblasts, the cells could proliferate without the need for animal sera. (nature.com)
- Using CRISPR genome-editing technology to look at 600 million mouse cartilage cells , researchers began eliminating genes that influence how the cells proliferate and mature to determine which would influence skeletal changes . (medscape.com)
20233
- Burlington, Massachusetts, April 24, 2023 - MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, today announced the launch of its Ultimus ® Single-Use Process Container Film, designed to provide extreme durability and leak resistance for single use assemblies used for bioprocessing liquid applications. (sigmaaldrich.com)
- Ultimus ® Single-Use Process Container Film will be showcased at the 2023 Interphex in New York City from April 25th to 27th. (sigmaaldrich.com)
- This is a summary of the article "Genome-wide CRISPR screening of chondrocyte maturation newly implicates genes in skeletal growth and height-associated GWAS loci" in the Journal Cell Geonomics on April 14, 2023. (medscape.com)
Induce3
- cAMP analogues such as dibutyryl cAMP (dBcAMP) have been shown to induce the formation of processes in cultured primary astrocytes. (rupress.org)
- Two selective inhibitors of MLC kinase (MLCK), ML-9 and KT5926, as well as a calmodulin antagonist (W7), which would also inhibit MLCK activation, all induce astrocytic process growth implicating MLCK as a control point in process initiation. (rupress.org)
- This objective integrates into a bigger project that also aims to identify molecular mechanisms by which caveolin regulates anchorage-dependent signalling pathways and cell cycle progression and to identify oncogenes that induce constitutive surface localization of rafts (and hence Rac), and/or changes in phosphocaveolin localization. (europa.eu)
Nutrients5
- Here, we developed a novel medium containing nutrients extracted from microalga and cell-secreted growth factors. (nature.com)
- Thus, microalga is an optimal cell source to efficiently provide nutrients to animal muscle cells. (nature.com)
- Here, we propose a new approach wherein the nutrients in the culture medium are provided by a microalgae extract, and the FBS is replaced by growth factors in the CM. Figure 1 illustrates the preparation process of our serum-free and grain-derived-nutrient-free medium. (nature.com)
- According to studies, the nutrients and chemicals in plant foods can alter the expression of tumor suppressors and other genes, as well as impact cell signaling pathways, inflammation, and the self-destruction of abnormal cells. (medicinenet.com)
- Your digestive system breaks nutrients into parts small enough for your body to absorb and use for energy, growth, and cell repair. (nih.gov)
Microbial cells3
- Bioprocessing begins upstream, most often with culturing of animal or microbial cells in a range of vessel types (such as bags or stirred tanks) using different controlled feeding, aerating, and process strategies. (bioprocessintl.com)
- An established biofilm structure comprises microbial cells and EPS, has a defined architecture, and provides an optimal environment for the exchange of genetic material between cells. (cdc.gov)
- A biofilm is an assemblage of surface-associated microbial cells that is enclosed in an extracellular polymeric substance matrix. (cdc.gov)
Tissues7
- MiR-363-3p levels in GC tissues and cells were tested by qRT-PCR. (medscimonit.com)
- MiR-363-3p showed low levels in GC tissues and cells. (medscimonit.com)
- Tissues with rapidly dividing cells may be especially vulnerable to carcinogens. (cdc.gov)
- Light-emitting diodes (LED), originally developed for NASA plant growth experiments in space show promise for delivering light deep into tissues of the body to promote wound healing and human tissue growth. (researchgate.net)
- Most tumours begin growing within normal tissues (dormant) (a) until they out grow they nutrient availability of the local environment and cell death occurs alongside rapid cell division. (scientificamerican.com)
- In facial morphogenesis, neural crest cells migrate into the facial region, where they form the skeletal and connective tissue and all dental tissues except the enamel. (medscape.com)
- It is a source of energy for your body, including your cells, tissues, and organs. (medlineplus.gov)
Epithelial1
- First, rat liver epithelial RL34 cells were cultured by adding Chlorella vulgaris extract (CVE) to inorganic salt solution. (nature.com)
Receptors2
- Growth factors act on two completely different types of cellular receptors. (eurekalert.org)
- Both LPA effects on cell growth and levels of ROS were totally abrogated by physiological concentrations of ANP, without modifying the overexpression of LPA-receptors. (mcw.edu)
Progression2
- This specific project aims to identify sequences within caveolin involved in regulation of raft internalisation, cell cycle progression and anchorage-dependent cell growth. (europa.eu)
- The rate of growth and progression of adenomas to cancer is variable, but typically occurs in 10-15 years. (medscape.com)
Adhesion2
- These studies will contribute to a better understanding of adhesion-dependent signalling and anchorage-dependence of cell growth, and therefore to the pathogenesis of the malignant disease. (europa.eu)
- The ECM provides structural and biochemical support to the cells and has various other functions including cell adhesion, cell to cell communication, and differentiation [ 17 , 18 ]. (hindawi.com)
Metabolism2
- With a minimalist model of metabolism, cell growth and transcriptional regulation in a microorganism, we explore how the interaction between environmental conditions and gene regulation set the growth rate of cells in the phase of exponential growth. (lu.se)
- A very natural place to study gene detecting and metabolizing lactose, it is known that the overall regulation is in the metabolism of the cell, and then specifically in effect of expressing the lac genes in vain is a drop in the growth rate the regulation of genes that code for enzymes and transporter of as much as 5% [1,6]. (lu.se)
Vaccine2
- The immune responses generated by recombinant vaccine outperformed those of both the cell-based and the standard dose flu vaccines made using traditional egg-based technology. (cdc.gov)
- A non-live, recombinant influenza virus vaccine not requiring isolation or growth in hen's eggs was licensed in 2013. (cdc.gov)
Inhibitors1
- Further studies are needed to establish the relationship between the initial process of resorption of the blood clot, and the involvement of MMPs 2 and 9 and its regulators/tissue inhibitors. (bvsalud.org)
Tumor formation2
- EGFR, when expressed aberrantly, can lead to cellular changes including runaway cell growth, reduced cell death, tumor formation and metastasis. (sciencedaily.com)
- The errors accumulate as the cells continue to divide, increasing the risk of tumor formation in the colon or another part of the body. (medlineplus.gov)
Abnormal cells1
- These errors accumulate as the abnormal cells continue to divide. (medlineplus.gov)
Vaccines3
- Sotio has selected local CRO Accord Research to carry out Phase I/II trials on its dendritic cell vaccines to treat patients with lung cancer in the Czech Republic. (outsourcing-pharma.com)
- Technological advancement in the downstream purification technology to develop high-quality products such as Vaccines at lower costs is expected to drive the growth of this segment. (marketsandmarkets.com)
- Recombinant and cell-based vaccines are produced using a different production process that does not require growth in eggs. (cdc.gov)
Differentiation1
- The differentiation of mesenchymal stem cells (MSCs) into multiple cell lineages can be exploited as an attractive strategy for cell-based therapy and regenerative medicine [ 1 ]. (hindawi.com)
Various cellular1
- To do this the cancerous cells unlock various cellular growth checkpoints through mutation such as checking the DNA is in a good condition before division or could start to release factors that accelerate their own growth. (scientificamerican.com)
Epidermal1
- We demonstrate that the competence of the root epidermal cells for the BR response predominantly depends on the amount and activity of H+-ATPases in the PM. The model further predicts that an influx of cations is required to compensate for the shift of positive charges caused by the apoplastic acidification. (elifesciences.org)
Blood vessels2
- Diabetes can have serious complications like gangrene and skin ulcers due to a restriction of blood supply to and healing capacity of the affected areas and this causes the dysfunction of cells lining the blood vessels. (eurekalert.org)
- p75NTR acts by depressing the cell's normal signalling mechanisms that are necessary to stimulate the growth of new blood vessels. (eurekalert.org)
Inflammatory cells1
- In people with psoriasis, immune system dysfunction causes inflammatory cells to build up in the middle layer of the skin, known as the dermis. (medicalnewstoday.com)
Hormones1
- Nerves and hormones help control the digestive process. (nih.gov)
Synthesis1
- Our Advanced Materials programme has expertise to cover everything from materials synthesis, analysis and characterisation through to processing and device fabrication. (warwick.ac.uk)
Survival3
- The conventional adenoma-carcinoma sequence is thought to be a genetically driven process characterized by the occurrence over time of successive cycles of somatic mutation and clonal expansion of cells that have acquired a survival advantage. (medscape.com)
- This activation led to enhanced survival of brain tumor cells following radiation or treatment with temozolomide," said Zhang. (mdanderson.org)
- Materials and Methods: We have adapted the Burkitt's lymphoma line Ramos to a serum-free medium that supports long-term survival and studied gene expression changes that occurred during the adaptation process. (lu.se)
Exponential1
Factors5
- The supernatant, containing the RL34 cell-secreted growth factors, was used as the conditioned medium (CM). This CM, with CVE added as a nutrient source, was applied to primary bovine myoblast cultures. (nature.com)
- The culture supernatant of animal cells, also known as 'conditioned medium' (CM), contains various factors secreted by the cells themselves, such as growth factors and cytokines. (nature.com)
- Dr Costanza Emanueli, BHF Reader at Bristol University and colleagues at the Bristol Heart Institute have previously found that a group of growth factors - known as neurotrophins - play a role in the vascular system. (eurekalert.org)
- Based on the results of this study, not only did the team discover the main factors for improving the quality of crystals during rapid growth on porous silicon used for the lift-off process, they succeeded in controlling these. (electroiq.com)
- Published September 5, 2007 transcription factors and replicating extra DNA, rather than going directly into growth of the cell. (lu.se)
Nasal2
- The upper lip is derived from medial nasal and maxillary processes. (medscape.com)
- Failure of merging between the medial nasal and maxillary processes at 5 weeks' gestation, on one or both sides, results in CL. (medscape.com)
Regulate1
- Considering from the initial stage of blood clot formation to the last stage of newly-formed bone tissue remodeling, several cells and signaling molecules are involved which regulate (and are also regulated) during the development of this process. (bvsalud.org)
20161
- 139 Pages Report] The global downstream processing market is poised to reach USD 22.03 Billion by 2021 from USD 10.32 Billion in 2016, at a CAGR of 16.4% from 2016 to 2021. (marketsandmarkets.com)
Regulation5
- This module provides an up to date understanding of how fundamental research in bacterial cell biology helps to elucidate central biological questions such as the control and regulation of cell division and of gene expression in bacteria. (ncl.ac.uk)
- Biofilm-associated cells can be differentiated from their suspended counterparts by generation of an extracellular polymeric substance (EPS) matrix, reduced growth rates, and the up- and down- regulation of specific genes. (cdc.gov)
- Here, the function of regulation is quite clear: expressing energy and carbon, that a number around 0.2% would be the right genes at the right time will enable the cell to make the expected, and that the difference is more or less specific to the lac most of the resources within its reach, by maximizing the uptake operon [7]. (lu.se)
- In unicellular organisms like E. coli and yeast, the benefits of between potential cost and benefit, regulation can make the most a well-adapted regulatory system are readily quantified, as the difference to the long-term growth rate if the resource in question fitness of an individual can be estimated by its growth rate in is only available a similarly small fraction of the time. (lu.se)
- A number of studies have explored how regulation of generally, and at least to a first approximation, it is obvious that metabolic pathways affects the growth rate of microorganisms, gene regulation only is useful if the environmental conditions vary both in the steady state and in response to changes in the local with time. (lu.se)
Semiconductor thin films1
Immune1
- These cells process antigen material and present it on the cell surface to the T cells of the immune system, acting as messengers between the innate and the adaptive immune systems. (outsourcing-pharma.com)
Substrate3
- Next, the surface was smoothed to a roughness of 0.2 to 0.3 nm via a unique zone heating recrystallization method (ZHR method), and this substrate was used for high-speed growth to obtain a moonocrystalline thin film with high crystal quality. (electroiq.com)
- The grown film can easily be peeled off using the double-layer porous Si layer, and the substrate can be reused or used as an evaporation source for thin film growth, which greatly reduces material loss. (electroiq.com)
- The extracellular matrix (ECM) provides structural and biochemical support to the surrounding cells, and it has been used as a coating substrate for cell culture. (hindawi.com)
Degradation2
- Microorganisms, like bacteria and fungi, are becoming an emerging resource for the development of eco-sustainable plastic degradation and recycling processes. (frontiersin.org)
- Both the structure of the PGs and the GAG chains, and the expression of the enzymes involved in their biosynthesis and degradation, vary between normal cells and tumor cells. (lu.se)
Molecular2
- Our study investigated the role of extracellular methylation in EGFR signaling, and unexpectedly discovered new information about how EGFR renders cancer cells resistant to cetuximab antibody therapy," said Mien Chie Hung, Ph.D., chair of Molecular and Cellular Oncology. (sciencedaily.com)
- Cellular senescence is a complex process, and its molecular mechanisms are unknown. (hindawi.com)
Inhibit1
- A low-glycemic diet minimizes spikes in blood sugar levels after eating, which can inhibit cancer cell growth and reproduction. (medicinenet.com)
Skeletal1
- Researchers identified 145 genes in mouse cartilage cells that were similar to those seen in certain skeletal disorders that affect the growth development of bones, joints, and cartilage in human babies . (medscape.com)
Downstream1
- Beginning with harvest of material from a bioreactor, downstream processing removes or reduces contaminants to acceptable levels through several steps that typically include centrifugation, filtration, and/or chromatographic technologies. (bioprocessintl.com)
Insulin2
- We have previously reported that in the well-differentiated β-cell line MIN6 cells, theβ-cell-specific differentiated characteristics, such as insulin content, expression of prohormone convertases PC2 and PC3, and glucose-regulated insulin secretion, diminished when the proprotein-processing endoprotease furin was highly expressed. (diabetesjournals.org)
- RINm5F cells exhibited the strongest furin expression, higher furin-type endoprotease activity, and the fastest cell growth, but had the least insulin content. (diabetesjournals.org)
Solar cells4
- Moreover, the BAFAMA perovskite solar cells demonstrate decent stability, maintaining 95% of their initial power conversion efficiency after 2600 h ambient storage, and 4-time operation condition lifetime enhancement. (edu.hk)
- Therefore, it can be expected that this technology will make it possible to drastically reduce manufacturing costs while maintaining the power generation efficiency of monocrystalline silicon solar cells, which are used in most high efficient solar cells. (electroiq.com)
- By making the monocrystalline Si solar cells that are at the core of solar power generation systems thinner, it is possible to greatly reduce raw material costs, which account for about 40% of the current module, and by making them flexible and lighter, usage can be expected to expand and installation costs can be expected to decrease. (electroiq.com)
- In addition, as a method of reducing manufacturing cost, thin-film monocrystalline Si solar cells that use porous silicon (Double Porous Silicon Layer: DPSL) via lift-off are attracting attention as having a competitive edge in the future. (electroiq.com)
Microorganisms2
- For most of the history of microbiology, microorganisms have primarily been characterized as planktonic, freely suspended cells and described on the basis of their growth characteristics in nutritionally rich culture media. (cdc.gov)
- Rediscovery of a microbiologic phenomenon, first described by van Leeuwenhoek, that microorganisms attach to and grow universally on exposed surfaces led to studies that revealed surface-associated microorganisms (biofilms) exhibited a distinct phenotype with respect to gene transcription and growth rate. (cdc.gov)
Subsequent2
- The model, consisting of ordinary differential equations, comprises the BR induced hyperpolarization of the PM, the acidification of the apoplast and subsequent cell wall swelling. (elifesciences.org)
- In situ GIWAXS visualizes the BA-related intermediate phase formation at the bottom of film, which serves as a guiding template for the bottom-up quasi-epitaxial growth in the subsequent annealing process. (edu.hk)
Actin3
- The most prominent cytoskeletal change that occurs in response to dBcAMP is a rearrangement of actin filaments characterized by a loss of cortical F-actin staining and the appearance of actin filament staining at the tips of the processes. (rupress.org)
- If cortical actin filaments are disrupted with dihydrocytochalasin B, processes form that are similar to those induced by dBcAMP suggesting that the disruption of the cortical actin network is the pivotal step in process formation. (rupress.org)
- Actin and nucleus are shown in green and blue to demarcate cell cytoplasm and nuclear area, respectively. (eurekalert.org)
Somatic1
- These changes are present only in certain cells (somatic variants), whereas NF1 gene variants that are present in all cells of the body cause neurofibromatosis type 1. (medlineplus.gov)
Carcinogens1
- Dietary fiber can protect you against cancer by helping waste pass through the digestive, diluting possible carcinogens and minimizing cells to their exposure. (medicinenet.com)
Rate6
- A research team from Tokyo Institute of Technology (Tokyo Tech) and Waseda University have successfully produced high-quality thin film monocrystalline silicon with a reduced crystal defect density down to the silicon wafer level at a growth rate that is more than 10 times higher than before. (electroiq.com)
- A joint research team consisting of Professor Manabu Ihara and Assistant Professor Kei Hasegawa of the Tokyo Tech, and Professor Suguru Noda of Waseda University has developed a high-quality thin film monocrystalline silicon with a thickness of about 10 μm and a reduced crystal defect density down to the silicon wafer level at a growth rate that is more than 10 times higher than before. (electroiq.com)
- This chapter of the report mentions the market share and growth rate of each region, country and sub-region during the estimated period. (digitaljournal.com)
- MSCs on PLL-coated plates exhibited a faster growth rate with increased S-phase and upregulated expression of the stemness markers. (hindawi.com)
- The growth rate during the first few months of life following birth is faster than during the rest of life. (cdc.gov)
- Children's growth velocity decreases smoothly at approximately 9 months of age - to about half the initial rate. (cdc.gov)
Cancer cells3
- In the case of glioblastoma, the most common and aggressive type of glioma or brain cancer, it can also allow the disease to progress more quickly when it is "enhanced," allowing damaged or mutated cancer cells to repair themselves. (mdanderson.org)
- Enhanced DNA repair can allow these cancer cells to survive, contributing to resistance and tumor recurrence. (mdanderson.org)
- The ability of cancer cells to promote angiogenesis is seen in almost all tumours that exceed 1 mm in diameter or become located 100 mm. from the nearest blood vessel. (scientificamerican.com)