• human
  • It is envisaged that the development of methods enabling controlled differentiation of mouse ES cell counterparts from human blastocysts would enable the provision of an unlimited supply of tissue for cell and tissue transplantation therapies for the repair and replacement of diseased, injured, and senescent tissue. (currentprotocols.com)
  • mouse ES cells
  • Furthermore, derivation of mouse ES cells has allowed for the generation of thousands of gene‐targeted mouse mutants. (currentprotocols.com)
  • Culture of mouse ES cells as embryoid bodies (EBs) has provided a convenient system for studying early mouse developmental processes, including several aspects of extraembryonic lineage and axis formation associated with the pre‐ and peri‐gastrulating mouse embryo. (currentprotocols.com)
  • One of the seminal achievements of mammalian embryology of the last decade is the routine insertion of specific genes into the mouse genome through the use of mouse ES cells. (google.es)
  • Mouse ES cells maintain an undifferentiated state through serial passages when cultured in the presence of fibroblast feeder layers in the presence of Leukemia Inhibitory Factor (LIF) (Williams, et al. (google.es)