• progenitor
  • During asymmetric stem cell division, both the daughter stem cell and the presumptive intermediate progenitor cell inherit cytoplasm from their parental stem cell. (biologists.org)
  • Thus, proper specification of intermediate progenitor cell identity requires an efficient mechanism to rapidly extinguish the activity of self-renewal factors, but the mechanisms remain unknown in most stem cell lineages. (biologists.org)
  • During asymmetric division of a type II neural stem cell (neuroblast) in the Drosophila larval brain, the Brain tumor (Brat) protein segregates unequally into the immature intermediate neural progenitor (INP), where it specifies INP identity by attenuating the function of the self-renewal factor Klumpfuss (Klu), but the mechanisms are not understood. (biologists.org)
  • Thus, the Brat-dependent mechanism extinguishes the function of the self-renewal factor Klu in the presumptive intermediate progenitor cell by attenuating Arm activity, balancing stem cell maintenance and progenitor cell specification. (biologists.org)
  • adult
  • 3.2 Core Blood Stem Cells Core blood stem cells are a source of adult stem cells which are found in the blood of the placenta and umbilical cord which is left over from birth, and have been used to treat Leukemia, Hunters Syndrome and many other conditions that usually occur in children (ref.www.wikipedia.com). (markedbyteachers.com)
  • mouse ES cells
  • Furthermore, derivation of mouse ES cells has allowed for the generation of thousands of gene‐targeted mouse mutants. (currentprotocols.com)
  • Culture of mouse ES cells as embryoid bodies (EBs) has provided a convenient system for studying early mouse developmental processes, including several aspects of extraembryonic lineage and axis formation associated with the pre‐ and peri‐gastrulating mouse embryo. (currentprotocols.com)
  • One of the seminal achievements of mammalian embryology of the last decade is the routine insertion of specific genes into the mouse genome through the use of mouse ES cells. (google.es)
  • Mouse ES cells maintain an undifferentiated state through serial passages when cultured in the presence of fibroblast feeder layers in the presence of Leukemia Inhibitory Factor (LIF) (Williams, et al. (google.es)
  • lines
  • A mass of cells descending from the original cell, which share genetic characteristics are created and batches are then separated from the mass used by researchers to develop treatments for illness (these masses are called cell-lines). (markedbyteachers.com)