• pathophysiology
  • Given that the bioactive lipid sphingosine 1-phosphate is involved in cardiovascular pathophysiology, and since lipid accumulation and inflammation are hallmarks of calcific aortic stenosis, the role of sphingosine 1-phosphate on the pro-inflammatory/pro-osteogenic pathways in human interstitial cells from aortic and pulmonary valves was investigated. (jove.com)
  • adverse
  • Thus, Dr. Pickering was one of the earliest researchers to employ ambulatory blood pressure (ABP) monitoring, and contributed to the knowledge that clinic blood pressure measures are prone to both unsystematic and systematic errors, and are hence less useful for the prediction of target organ damage and adverse cardiovascular events than ABP. (wikipedia.org)
  • Perspective
  • The organization and function of the central and peripheral nervous systems will be presented from a correlated anatomical, physiological, and pharmacological perspective by means of lectures and conferences, and by laboratory exercises that incorporate dissection of the brain. (dartmouth.edu)
  • Brain
  • Taurine crosses the blood-brain barrier and has been implicated in a wide array of physiological phenomena including inhibitory neurotransmission, long-term potentiation in the striatum/hippocampus, membrane stabilization,[unreliable medical source? (wikipedia.org)
  • health
  • Ideal cardiovascular health is inversely associated with incident cancer: the Atherosclerosis Risk In Communities study. (naver.com)
  • Dr. Pickering continued his work as Director of the Integrative and Behavioral Cardiology Program at Mount Sinai Hospital in New York City in 2000, finally relocating to Columbia University Medical Center in New York City in 2003 to form the Center for Behavioral Cardiovascular Health where he worked until his death in 2009. (wikipedia.org)
  • damage
  • Dr. Pickering was the Principal Investigator of a National Heart Lung and Blood institute Program Project that began in 1993 and has investigated several phenomena related to the behavioral causes and physiological consequences of hypertension, focusing on white coat hypertension, nocturnal blood pressure "dipping", race differences in PSG-assessed sleep quality and target organ damage, and the effects of work-related stress on blood pressure and left ventricular hypertrophy (LVH). (wikipedia.org)
  • function
  • Peptides derived from the prohormone proNPQ/spexin are potent central modulators of cardiovascular and renal function and nociception. (nih.gov)
  • rats
  • NPQ/spexin (NWTPQAMLYLKGAQ-NH(2)) and NPQ 53-70 (FISDQSRRKDLSDRPLPE) have differing renal and cardiovascular effects when administered intracerebroventricularly or intravenously into rats. (nih.gov)
  • membrane
  • Furthermore, PC made via PEMT plays a wide range of physiological roles, utilized in choline synthesis, hepatocyte membrane structure, bile secretion, and very-low-density lipoprotein (VLDL) secretion. (wikipedia.org)
  • patients
  • for example, he was one of the first to identify the phenomenon of "white coat hypertension", in which patients exhibit poor blood pressure control only in the physician's office, leading to a false diagnosis of hypertension and unnecessary prescription of medication. (wikipedia.org)
  • control
  • Spectral analysis of RR interval and systolic arterial pressure variabilities may provide indirect markers of the balance between sympathetic and vagal cardiovascular control. (labome.org)
  • There is anatomic and physiological evidence for a polyvagal control of the heart. (wikipedia.org)
  • changes
  • Stimuli were presented over a very short period of time such that subjects were not consciously aware of the stimuli but were still able to show physiological changes. (wikipedia.org)
  • blood
  • He coined the term "white-coat hypertension" to describe those whose blood pressure was elevated in the doctor's office, but normal in everyday life, and later published the first editorial describing "masked hypertension" (the opposite phenomenon). (wikipedia.org)
  • important
  • It is important to differentiate between physiological adaptations to mild hypoxia and re-oxygenation episodes (i.e., the IHT protocol) and frequent nocturnal suffocation awakenings produced by sleep apnea, which might result in various pathologies. (wikipedia.org)