• diabetes
  • Secondary diabetes is carbohydrate intolerance secondary to pancreatic disease, excess production of certain hormones (eg, growth hormone), use of certain drugs (eg, corticosteroids), insulin receptor abnormalities, and certain genetic disorders. (health.am)
  • These risk factors increase the risk for heart disease, diabetes, and stroke. (nyhq.org)
  • risk factors
  • With multivariate analysis that included the classic risk factors for coronary artery disease, elevated CRP serum level remained a statistically significant independent predictor of a blunted endothelial vasodilator capacity. (ahajournals.org)
  • patients
  • Background -Elevated C-reactive protein (CRP) serum levels, an exquisitely sensitive objective marker of inflammation, relate to long-term prognosis in patients with coronary artery disease and in apparently healthy men. (ahajournals.org)
  • Methods and Results -Endothelium-dependent (10 to 50 μg/min acetylcholine) and endothelium-independent (2 to 8 μg/min sodium nitroprusside) forearm blood flow responses were measured with venous occlusion plethysmography in 60 male patients with angiographically documented coronary artery disease. (ahajournals.org)
  • 2 3 4 Importantly, not only is the presence of systemic markers of inflammation associated with an unfavorable short-term prognosis in patients with acute coronary syndromes, 3 4 but also elevated CRP levels are related to long-term prognosis in patients with documented coronary artery disease 5 and in apparently healthy men. (ahajournals.org)
  • 11 Therefore, we tested the hypothesis that elevated CRP levels, an exquisitely sensitive objective marker of inflammation, are associated with an abnormal systemic endothelial vascular reactivity in patients with coronary artery disease. (ahajournals.org)
  • Twenty-six patients had stable angina, defined as angiographically documented coronary artery disease and stable effort angina for ≥3 months before forearm blood flow (FBF) measurements. (ahajournals.org)
  • All patients had documented coronary artery disease with identification of the culprit lesion on coronary angiography. (ahajournals.org)