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  • metaplasia
  • Another possible way of SCTC development can be through the squamous metaplasia of cells. (wikipedia.org)
  • However, that theory is also controversial, since the Hashimoto's thyroiditis and chronic lymphocytic thyroiditis (neoplasms to be showed squamous metaplasia) are not associated with SCTC. (wikipedia.org)
  • cancers
  • If cancers cells are present at the tissue edge, additional tissue is removed. (innerbody.com)
  • Squamous cell cancers are considered superficial when the upper part of the dermis is involved and infiltrative when the lower dermis and fat tissues under the skin (subcutaneous) are invaded. (healthcentral.com)
  • The eosinophil cell has been related as a prognostic indicator for cancers. (hindawi.com)
  • epidermal
  • Several studies have found an association between the presence of Bovine papillomavirus-1 and 2 and associated viral growth proteins in skin cells with sarcoid formation, but the exact mechanism that controls or induces epidermal proliferation remains unknown. (wikipedia.org)
  • Mohs
  • At Moffitt, we offer a complete range of treatments for squamous cell carcinoma, from Mohs micrographic surgery (offered in conjunction with the USF Department of Dermatology) to targeted radiation therapy. (moffitt.org)
  • histologically
  • Around 1/3 progress to squamous cell carcinoma 2) Erythroplasia of Queyrat, a variation of Bowen's disease, presenting as erythroplakia on the glans 3) Bowenoid papulosis, which histologically resembles Bowen disease, but presents as reddish papules. (wikipedia.org)
  • Histologically, sarcoids are composed of fibroblasts (collagen producing cells) that invade and proliferate within the dermis and sometimes the subcutaneous tissue but do not readily metastasize to other organs. (wikipedia.org)
  • skin
  • Squamous cells are thin cells found in the most superficial layer of the skin ( epidermis ) and other mucous membranes in the body. (innerbody.com)
  • Histopathological characteristics of metastasizing squamous cell carcinoma of the skin and lips," Histopathology , vol. 49, no. 3, pp. 256-264, 2006. (hindawi.com)
  • These cells form the surface of the skin lining of hollow organs in the body and line the respiratory and digestive tracts. (wikipedia.org)
  • distinct
  • For microscopic appearance, the SCC cells arranged in nests, which are surrounded of polygonal cells with distinct cell borders and hyperchromatic nuclei. (springer.com)
  • tumor
  • This study will also look at specific substances called biomarkers in your blood, and in the tumor tissue which are involved in the growth of tumor cells, and determine if the levels of these biomarkers are related to your response to treatment or development of side effects. (clinicaltrials.gov)
  • According to Dr. McEntee, the most frequently diagnosed skin malignancy by far is a mast cell tumor. (kerryblues.org)
  • Nasopharyngeal carcinoma (NPC) is a frequent tumor in southern China and its etiopathogenesis is not clear. (scitechnol.com)
  • receptor
  • Pasireotide works by binding to a protein called somatostatin receptor, which is expressed in many tissues throughout the body including thyroid cancer cells. (clinicaltrials.gov)
  • It targets the programmed cell death 1 (PD-1) receptor of lymphocytes. (wikipedia.org)
  • Pembrolizumab is an immunoglobulin G4, with a variable region against the human programmed cell death 1 receptor, a humanized mouse monoclonal [228-L-proline(H10-S>P)]γ4 heavy chain (134-218') disulfide and a humanized mouse monoclonal κ light chain dimer (226-226:229-229)-bisdisulfide. (wikipedia.org)
  • A signature of this type of receptor is the distinct pattern of how the receptor molecule spans the cell membrane seven times. (wikipedia.org)
  • tissue
  • This galectin is strongly overexpressed in Hodgkin's disease tissue and it might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its consistently associated immunodeficiency. (wikipedia.org)
  • protein
  • Pembrolizumab is a therapeutic antibody that binds to and blocks the PD-1, programmed cell death protein 1 located on lymphocytes. (wikipedia.org)
  • Leukocyte cell-derived chemotaxin-2 (LECT2) is a protein first described in 1996 as a chemotactic factor for neutrophils, i.e. it stimulated human neutrophils to move directionally in an in vitro assay system. (wikipedia.org)
  • Subsequent studies have defined LECT2 as a hepatokine, i.e. a substance made and released into the circulation by liver hepatocyte cells that regulates the function of other cells: it is a hepatocyte-derived, hormone-like, signaling protein. (wikipedia.org)
  • The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. (wikipedia.org)
  • growth
  • It is due to the abnormal growth of cells that have the ability to invade or spread to other parts of the body. (wikipedia.org)
  • These gene products are important in determining cell fates during normal development and in maintaining homeostasis, or they can lead to de-regulated growth in disorders like cancer by responding to mutations in β-catenin, APC or Axin, each of which can lead to this de-regulated β-catenin level stabilization in cells. (wikipedia.org)
  • While less attention is directed at α-catenin in studies involving cell adhesion, it is nonetheless an important player in cellular organization, function and growth. (wikipedia.org)
  • Origin
  • Esthesioneuroblastoma is of neurocrest origin, arising from olfactory sensory cells in the olfactory epithelium. (wikipedia.org)
  • function
  • In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. (wikipedia.org)
  • known
  • Arising from the upper nasal tract, esthesioneuroblastoma is believed to originate from sensory neuroepithelial cells, also known as neuroectodermal olfactory cells. (wikipedia.org)