• Cancer
  • Some cancers are initiated when exogenous factors introduce mutations, such as ultraviolet radiation (skin cancers) and tobacco (lung cancer). (wikipedia.org)
  • Safety and Efficacy Study of rhAngiostatin Administered in Combination With Paclitaxel and Carboplatin to Patients With Non-Small-Cell Lung Cancer - Full Text View - ClinicalTrials.gov Cao Y, Ji RW, Davidson D, et al. (wikipedia.org)
  • Margaret Adaline Reed Lewis (1881-1970) was an American cell biologist and embryologist who made contributions to cancer research and cell culture techniques, and was likely the first person to successfully grow mammalian tissue in vitro. (wikipedia.org)
  • Tissue
  • The tissue grown in this medium was prepared in a method that become known as the "Lewis Culture" where the tissue bits were put into a hanging drop on the underside of a thin glass slip. (wikipedia.org)
  • In her work with chick embryos, Margaret Lewis studied connective tissue formation within the tissues as well as outside of an environment where factors involved in coagulation are present. (wikipedia.org)
  • cell
  • Since the Lewises main interest was microscopic cell structures, their objective was to create optically clear media, which led to the creation of the Locke-Lewis solution. (wikipedia.org)
  • With so many avenues opened by cell culture to explore, Margaret Lewis and her husband diverged in their area of study, with Margaret Lewis choosing to focus on microbiological problems, which involved close observations of chick embryo intestines reacting to typhoid bacilli in the medium in which it was grown. (wikipedia.org)