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  • allergic
  • You should not take carbamazepine if you have a history of bone marrow suppression, if you are also taking nefazodone, or if you are allergic to an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), desipramine (Norpramin), imipramine (Tofranil), or nortriptyline (Pamelor). (cardiosmart.org)
  • Tell your doctor if you have ever had any unusual or allergic reaction to carbamazepine or any other medicines. (drugs.com)
  • WARNINGS
  • In the US, the label for carbamazepine contains warnings concerning: effects on the body's production of red blood cells, white blood cells, and platelets: rarely, there are major effects of aplastic anemia and agranulocytosis reported and more commonly, there are minor changes such as decreased white blood cell or platelet counts, that do not progress to more serious problems. (wikipedia.org)
  • nefazodone
  • Do not use carbamazepine if you also take nefazodone, or if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. (cardiosmart.org)
  • breakdown
  • Valproic acid and valnoctamide both inhibit microsomal epoxide hydrolase (MEH), the enzyme responsible for the breakdown of carbamazepine-10,11 epoxide into inactive metabolites. (wikipedia.org)
  • potentially
  • Carbamazepine also increases the metabolism of the hormones in birth control pills and can reduce their effectiveness, potentially leading to unexpected pregnancies. (wikipedia.org)
  • side
  • Carbamazepine is very effective and I did not experience any side effects, but we must not forget that everyone reacts differently to medication. (drugs.com)
  • this unusual side effect is usually not noticed by most people, and disappears after the person stops taking carbamazepine. (wikipedia.org)
  • taken
  • Carbamazepine was compared with no active medication ('dummy' or placebo treatment), versus an antipsychotic or when taken in addition to an antipsychotic. (cochrane.org)
  • problems
  • Although appropriate studies on the relationship of age to the effects of carbamazepine have not been performed in the geriatric population, geriatric-specific problems are not expected to limit the usefulness of carbamazepine in the elderly. (drugs.com)
  • Unsafe blood cell count problems have happened with this medicine (carbamazepine sustained-release capsules). (drugs.com)
  • treatment
  • Larger well-designed trials are necessary to provide stronger evidence before carbamazepine can be recommended as a treatment for people with schizophrenia. (cochrane.org)
  • One study comparing carbamazepine with placebo as the sole treatment for schizophrenia was abandoned early due to high relapse rate with 26 out of 31 participants relapsing by three months. (cochrane.org)
  • Carbamazepine is typically used for the treatment of seizure disorders and neuropathic pain. (wikipedia.org)
  • active
  • By inhibiting MEH, valproic acid and valnoctamide cause a build-up of the active metabolite, prolonging the effects of carbamazepine and delaying its excretion. (wikipedia.org)