• Epoxide
  • Though clinical activity for the epoxide has been postulated, the significance of its activity with respect to the safety and efficacy of carbamazepine has not been established. (nih.gov)
  • Valproic acid and valnoctamide both inhibit microsomal epoxide hydrolase (MEH), the enzyme responsible for the breakdown of carbamazepine-10,11 epoxide into inactive metabolites. (wikipedia.org)
  • WARNINGS
  • In the US, the label for carbamazepine contains warnings concerning: effects on the body's production of red blood cells, white blood cells, and platelets: rarely, there are major effects of aplastic anemia and agranulocytosis reported and more commonly, there are minor changes such as decreased white blood cell or platelet counts, that do not progress to more serious problems. (wikipedia.org)
  • 2017
  • The report presents a detailed assessment of the market dynamics, growth trends, and opportunities that will impact the progression of the global carbamazepine market between 2017 and 2025. (sbwire.com)
  • Pharma
  • Some of the leading players in the carbamazepine market are Novartis AG, Jubilant Pharma, Jiangsu Tohope, Shanghai Modern Hasen, Zhejiang Jiuzhou, and Jinan Jinda. (sbwire.com)
  • toxicity
  • Before prescribing carbamazepine, the physician should be thoroughly familiar with the details of this prescribing information, particularly regarding use with other drugs, especially those which accentuate toxicity potential. (nih.gov)
  • medication
  • Carbamazepine is very effective and I did not experience any side effects, but we must not forget that everyone reacts differently to medication. (drugs.com)
  • Carbamazepine was compared with no active medication ('dummy' or placebo treatment), versus an antipsychotic or when taken in addition to an antipsychotic. (cochrane.org)
  • Carbamazepine interaction with Food, Herbs, Alcohol and Caffeine It is important to know how to take the medication to avoid the drug-food interaction. (medindia.net)
  • reduces
  • Carbamazepine greatly reduces or abolishes pain induced by stimulation of the infraorbital nerve in cats and rats. (nih.gov)
  • There is therefore a lack of evidence whether carbamazepine reduces symptoms and side effects in people with schizophrenia or similar mental health problems. (cochrane.org)
  • doses
  • Recommended doses of carbamazepine vary greatly, depending on the condition being treated and the age and circumstances of the person being treated. (pharmasave.com)
  • affective
  • Moreover, carbamazepine is used for the treatment of mania and for maintaining the treatment of bipolar affective disorders or to prevent recurrence. (sbwire.com)
  • alcohol
  • Carbamazepine USP is a white to off-white powder, practically insoluble in water and soluble in alcohol and in acetone. (nih.gov)
  • The increasing number of individuals suffering from alcohol withdrawal disorders, central partial diabetes insipidus or water diabetes, and psychotic disorders is also driving the carbamazepine market. (sbwire.com)
  • Alcohol use while taking carbamazepine may lead to enhanced depression of the central nervous system. (wikipedia.org)
  • side effects
  • People taking carbamazepine should report any side effects of concern (such as flu-like symptoms, unexplained weight loss, jaundice, confusion, depression, thoughts of self-harm) to a doctor as these may signal a more serious underlying condition. (drugs.com)
  • A controlled release formulation about carbamazepine was available by the FDA as of 2014, which provides tentative evidence regarding fewer side effects of the drug. (sbwire.com)
  • blood
  • Unsafe blood cell count problems have happened with this medicine (carbamazepine sustained-release capsules). (drugs.com)
  • Blood levels of carbamazepine are able to be monitored. (drugs.com)
  • however, the risk is extremely low although people exhibiting decreased platelet or white blood cell counts should be monitored closely and carbamazepine discontinued if the condition worsens. (drugs.com)