Capillary permeability. Medical search. Frequent questions

Transplantation-associated lung injury was characterized by an increased alveolar-capillary permeability and myeloperoxidase activity and decreased levels of arterial oxygen tension/inspired oxygen concentration ratio. (greenmedinfo.com)

Intratracheal administration of AdVEGF165 resulted in a dose-dependent increase in lung wet/dry weight ratios over time, lung histology showed widespread intra- alveolar edema, and pulmonary capillary permeability was significantly increased as quantified by the Evans blue dye assay and [(131)I]albumin permeability. (nih.gov)
OKT3 and pulmonary capillary permeability. (bmj.com)

Systemic capillary leak syndrome (SCLS) is an ex- of Zika virus in Brazil and the Americas. (cdc.gov)
The systemic capillary leak syndrome (SCLS) is an extremely rare disorder characterized by transient episodes of hypotensive shock due to reversible vascular hyper-permeability. (nih.gov)

May decrease inflammation by reversing increased capillary permeability and suppressing PMN activity. (medscape.com)
Capillary permeability and inflammation in rabbits given heparin. (nih.gov)
CFE can cause capillary inflammation and breakdown of the blood-brain barrier, without associated hemorrhage or permanent neurologic deficit. (ajnr.org)

Together, these data suggest that overexpression of VEGF in the lung may be one mechanism of increased pulmonary vascular permeability in the early stages of acute lung injury. (nih.gov)
Application of episodic SCLS sera, but neither purified IgG nor sera obtained from subjects during remission, to human microvascular endothelial cells caused vascular endothelial cadherin (VE-Cad) internalization, disruption of cell-cell adherens junctions, actin stress fiber formation, and increased permeability in complementary functional assays without inducing endothelial apoptosis. (nih.gov)

It is unknown, however, whether this genetic profile is accompanied by disturbed macromolecular permeability of systemic capillary endothelium, possibly in the context of generalized endothelial dysfunction. (nih.gov)
VEGF regulates PCB 104-mediated stimulation of permeability and transmigration of breast cancer cells in human microvascular endothelial cells. (nih.gov)
pentachlorobiphenyl (PCB 104), a representative of highly ortho-substituted non-coplanar PCB congeners, on the endothelial permeability and transendothelial migration of MDA-MB-231 breast cancer cells. (nih.gov)
In the heart, endothelial staining is mainly in the capillaries of the myocardium and varies from focal immunostaining in some cases to diffuse and extensive staining in others. (cdc.gov)
Our results support a model of SCLS pathogenesis in which canonical permeability mediators such as VEGF and Angiopoietin 2, but not immunoglobulins, transiently activate pathogenic endothelial contraction pathways, suggesting a molecular mechanism and novel potential targets for this highly lethal disorder. (nih.gov)

the 1-h decline rate of intravenous (125)I-albumin, a measure of integrity of systemic capillary endothelium), albuminuria and forearm vasodilation to intra-arterial acetylcholine, an index of NO (nitric oxide)-mediated vasomotion, in addition to a series of sensitive parameters of albumin permeation (blood pressure, metabolic status and smoking habits). (nih.gov)
Immunohistochemistry analysis has shown that viral antigens are distributed primarily within the endothelium of capillaries throughout various tissues from patients with HPS. (cdc.gov)
Indeed, findings from recent animal model studies suggest that fat embolism can result in the breakdown of the capillary endothelium and the blood-brain barrier, causing focal vasogenic edema without infarction or hemorrhage ( 7 , 8 ). (ajnr.org)
The walls of capillaries are composed of only a single layer of cells, the endothelium. (confusedofcalcutta.com)

Albondin-mediated capillary permeability to albumin. (wikipedia.org)

It is unclear how the shock syndrome relates to factors such as viral distribution and immunologic and pharmacological mediators of capillary permeability. (cdc.gov)

Diabetic glomerulosclerosis is the result of thickening of the basement membrane of the glomerular capillaries and increased cellularity of the mesangium, along with an increase in the mesangial matrix. (pharmacology2000.com)
Glomerular permeability I. Ferritin transfer across the normal glomerular capillary wall. (wikipedia.org)

Kinins cause increased capillary permeability and venous constriction, along with arterial vasodilation in specific organs. (cvphysiology.com)

Model parameters were fit to both blood capillary permeability data and lymphatic clearance data. (cdc.gov)

Severe allergic reactions, such as anaphylaxis, can cause widespread capillary leakage and generalized edema. (labtestsguide.com)

Intravenous immunoglobulin (IVIG), one promising therapy for SCLS, mitigated the permeability effect of episodic sera. (nih.gov)
Two circulating permeability factors, VEGF and Angiopoietin 2 (Ang2), were significantly elevated in episodic SCLS sera. (nih.gov)

The model presently takes into account the changes in the relative permeability, capillary pressure, and capillary desaturation curves. (doe.gov)
This addition will provide a unique simulator that can model surfactant floods in naturally fractured reservoirs by coupling wettability effects on relative permeabilities, capillary pressure, and capillary desaturation curves. (doe.gov)

The mathematical models for segregated flow of CO2 plume below the seal accounting for capillary hysteresis, chemical reactions, and leakage allows maximizing CO2 entrapment by the rock until its arrival to the trap. (edu.au)
Inflammatory responses due to injuries, infections, or certain medical conditions can cause capillaries to become more permeable, leading to fluid leakage into the tissues. (labtestsguide.com)

Analysis of the derived pore occupancies leads to the establishment of a number of relationships showing the phase dependencies of three-phase capillary pressures and relative permeabilities in mixed-wet systems. (hw.ac.uk)
Detailed investigation of the morphology of the pore space in clay is a key factor in understanding the sealing capacity, coupled flows, capillary processes and associated deformation present in mudstones. (epj-conferences.org)

The swelling in edema happens when excess fluid, typically water, leaks out of tiny blood vessels (capillaries) and accumulates in the surrounding tissues. (labtestsguide.com)

In each region, we find that only one phase may be specified as being the 'intermediate-wetting' phase and it is only the relative permeability of this phase and the capillary pressure between the two remaining phases that depend upon more than one saturation. (hw.ac.uk)
We showed that the capillary end effect cannot be removed completely but can be reduced significantly by controlling the wellbore flowing pressure and by altering the formation wettability. (onepetro.org)
Hence, once the fresh fracturing water invades, the formation experiences large gas-water capillary pressure. (onepetro.org)
Passive congestion is due either to high blood pressure in the capillaries, caused by a cardiac disorder, or to relaxation of the blood capillaries followed by blood seepage. (britannica.com)
The blood pressure becomes high in the alveolar capillaries, and they begin to distend. (britannica.com)
Eventually the pressure becomes too great, and blood escapes through the capillary wall into the alveoli, flooding them. (britannica.com)
Available models generally assume that capillary pressure and relative permeability are unique functions of saturation. (civilica.com)
Non-equilibrium effects is introduced by a pair of effective water and gas saturations related to the actual saturations by the extension of Barenblatt model to three-phase systems considering dynamic effects in both relative permeability and capillary pressure functions. (civilica.com)

Perfusion" is defined as the steady-state delivery of blood to an element of tissue (ie, capillary blood flow). (ajnr.org)
When combined with existing models for stratum corneum permeability and appropriate measures of tissue binding, the developed model has the potential to significantly improve tissue concentration estimates for large or highly protein bound permeants following dermal exposure. (cdc.gov)
After the tissue has been perfused, capillaries widen to become venules and then widen more to become veins, which return blood to the heart. (confusedofcalcutta.com)
However, the metabolism- and tissue-dependent permeability of [ 11 C]-butanol presents challenges. (snmjournals.org)

On the design of test molds based on unidirectional saturated flows to measure transverse permeability in liquid composite molding. (polymtl.ca)
Blood flows from digestive system heart to arteries, which narrow into arterioles, and then narrow further still into capillaries. (confusedofcalcutta.com)

The simulation results show that the capillary end effect cause significant formation damage during the flow back and production period by holding the water volume and saturation near the fracture at higher levels than that based on only the spontaneous imbibition of water. (onepetro.org)

All of these mechanisms are favorable for increased capillary imbibition. (doe.gov)

Laboratory surfactant floods have shown a great potential to increase oil recovery from reservoirs that are naturally fractured and have low-permeability oil-wet or mixed- wet matrix rocks. (doe.gov)

In ultra-low permeability formations, such as tight gas and shale, the sizes of the pores and cracks contributing to the transport of fluids are significantly reduced. (onepetro.org)

Exchange capacity (permeability (P)-surface area (S) product relative to blood flow (FB)) was increased in test mice compared to controls, but the contributions from P, S, and FB were different in these two phenotypes. (uib.no)

The alveolar walls and the capillaries in them become distended with blood. (britannica.com)

The unidirectional influx of biotin across cerebral capillaries, the anatomical locus of the blood-brain barrier, was measured with an in situ rat brain perfusion technique employing [3H]biotin. (nih.gov)
Performance Evaluation of Unidirectional Molds used for Measuring Saturated Transverse Permeability of Engineering Textiles. (polymtl.ca)

Capillary end effect develops in tight gas and shale formations near hydraulic fractures during flow back of the fracturing treatment water and extends into the natural gas production period. (onepetro.org)

Previous studies have suggested that immune responses contribute to an increase in capillary permeability. (who.int)
Leading to hypotension and increase capillary permeability. (englishgratis.com)

A simple process-based model of three-phase displacement cycles for both spreading and non-spreading oils in a mixed-wet capillary bundle model is presented. (hw.ac.uk)
In this study, a new multi-phase reservoir flow simulation model is used to understand the role the capillary end effect plays on the removal of the water from the formation and on the gas production. (onepetro.org)
The model simulates water-gas flow in this network with a capillary discontinuity at the hydraulic fracture-matrix interface. (onepetro.org)
The dermal clearance model combined with existing models for stratum corneum permeability and appropriate measures of protein binding were used to analyze in vivo concentration data from the literature and compare it to predictions made by the current mathematical model. (cdc.gov)

However, these studies did not consider the existence of capillary end effect (CEE). (onepetro.org)

We aimed to study the physiological roles of these two components of the permeability barrier non-invasively in striated muscle in mice deficient in collagen XV or XVIII by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). (uib.no)
Immunohistochemistry and electron microscopy demonstrated alterations in capillary density and morphology in both knockout mouse strains in comparison to the control mice. (uib.no)

Both collagen XV and XVIII are important for maintaining normal capillary permeability in the striated muscle. (uib.no)

Children in septic disgust inclination much ask for larger volumes of running as a result of the increased capillary permeability. (daubnet.com)

Consequently, the two-phase flow dynamics during the flow-back could be controlled by capillary forces. (onepetro.org)

Anatomy5

Organisms2

Diseases6

Chemicals and Drugs7

Analytical, Diagnostic and Therapeutic Techniques and Equipment4

Phenomena and Processes9

Alveolar-Capillary Permeability1

Pulmonary capillary permeability2

Systemic capillar2

Inflammation3

Vascular2

Endothelial5

Endothelium4

Albumin1

Mediators1

Glomerular2

Vasodilation1

Lymphatic1

Widespread1

SCLS2

Curves2

Leakage2

Pore2

Edema1

Pressure8

Tissue4

Flows2

Saturation1

Mechanisms1

Reservoirs1

Significantly1

Relative1

Walls1

Unidirectional2

Develops1

Increase2

Model4

Effect1

Mice2

Normal1

Result1

Flow1