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  • corticosteroids
  • Medical therapy has very limited role in the treatment of calcinosis cutis but drugs like corticosteroids, probenecid, colchicine, sodium etidronate, diphosphonates, diltiazem, and magnesium and aluminium antacids can be used in order to relieve the symptoms9,10. (thefreedictionary.com)
  • tissues
  • In addition to being cosmetically unappealing, involvement of deeper tissues with calcinosis may lead to contractures, or shortening of muscles, which may have a significant impact on functioning and quality of life. (clinicaltrials.gov)
  • severity
  • Change in calcinosis severity visual analogue scale score from week 0 to week 10 on therapy, compared to the baseline change in calcinosis severity visual analogue scale score from week -10 to week 0 pre treatment. (clinicaltrials.gov)
  • skin
  • Calcinosis usually occurs in and just under skin tissue around the joints, most often the hips, shoulders, and elbows. (nih.gov)
  • U. H. G. Michl, A. J. Gross, V. Loy, and K. P. Dieckmann, "Idiopathic calcinosis of the scrotum-a specific entity of the scrotal skin. (hindawi.com)
  • 6) When calcinosis cutis is complicated by serious extravasation injuries, such as secondary infection or skin necrosis, debridement, drainage, or skin grafting may be needed. (thefreedictionary.com)