Objective: The aim of this study was to examine the calbindin D-28k immunoreactivity in carious teeth to know whether this protein may have a function in tertiary dentine formation. (elsevierpure.com)
Methods: Human extracted teeth with or without carious lesions were immersion-fixed with Zamboni fixative, demineralized in 4.13% EDTA solution (pH 7.4), frozen-sectioned, and processed for calbindin immunoreactivity and hematoxylin-eosin stain. (elsevierpure.com)
Left and middle: Detection of calbindin immunoreactivity in rat brain cerebellum (Left) and cortex (Middle) sections by Immunohistochemistry . (biosensis.com)
Alonso J.R. (1995) Calbindin D-28k immunoreactivity in the rat accessory olfactory bulb. (uv.es)
DeFelipe J, Hendry SH, Jones EG (1989) Synapses of double bouquet cells in monkey cerebral cortex visualized by calbindin immunoreactivity. (yale.edu)
NK 1 R immunoreactivity (NK 1 R-IR) is examined in whole-mount preparations of the mouse distal colon by indirect immunofluorescence and confocal microscopy. (nyu.edu)
CALB12
Calbindin 1 is a protein that in humans is encoded by the CALB1 gene. (wikipedia.org)
To explore these questions, we performed a genome -wide CRISPR screen in a cellular model of DBA and identified Calbindin 1 (CALB1), a member of the calcium -binding superfamily, as a potential modifier of the disordered erythropoiesis in DBA. (bvsalud.org)
D28k8
In this process, cytosolic Ca2+ remains at low nontoxic concentrations because the Ca2+ influx is buffered rapidly by calbindin-D28K. (researchwithrutgers.com)
Subsequently, Ca2+ that is bound to calbindin-D28K is shuttled toward the basolateral Ca2+ extrusion systems. (researchwithrutgers.com)
Calcium-binding proteins such as calbindin D28K and calretinin are used as markers of nervous and enteric nervous systems, but they are present in numerous other cells. (unime.it)
In this study we demonstrated, for the first time, the presence of calretinin and calbindin D28K in skin club cells of Danio rerio exposed to different wavelengths by immunohistochemistry analysis. (unime.it)
Exposure to white-blue light and blue light causes the expression and colocalization of calbindin-D28K and calretinin. (unime.it)
Calbindin-D28K expression induced by glial cell line-derived neurotrophic factor in substantia nigra neurons dependent on PI3K/Akt/NF-kappaB signaling pathway. (genscript.com)
NECAB2 was mainly present in excitatory synaptic boutons in the dorsal horn of all three species, and often in calbindin-D28k(+) neuronal somata. (scilifelab.se)
A calbindin protein that is differentially expressed in distinct populations of NEURONS throughout the vertebrate and invertebrate NERVOUS SYSTEM, and modulates intrinsic neuronal excitability and influences LONG-TERM POTENTIATION. (lookformedical.com)
In addition, basal expression levels of tight junction protein-1 encoding ZO1 were lower in R91W;Nrl −/− than in wt retinas. (nature.com)
Mutations in the Abelson helper integration site 1 gene, which encodes the protein AHI1, have been shown to cause Joubert syndrome. (jci.org)
In this study, we found that mouse Ahi1 formed a stable complex with huntingtin-associated protein 1 (Hap1), which is critical for neonatal development and involved in intracellular trafficking. (jci.org)
Product Description google Mouse anti-Calbindin-binding protein Monoclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen. (biosensis.com)
The band at ~25 kDa corresponds to calbindin protein, heavily expressed in the cerebellum, but less in hippocampus. (biosensis.com)
Our goals were twofold: 1) to characterize the gene expression, protein expression, and activity of key synthesizing and regulating enzymes of energy metabolism in the whole mouse retina, retinal compartments, and/or cells and 2) to provide an integrative analysis of the results related to function. (molvis.org)
The structure of calbindin is characteristic of an EF-hand protein, with two helix-loop-helix calcium binding motifs joined by a flexible linker, and a short anti-parallel beta-type interaction between the two ion-binding sites. (molmovdb.org)
In addition, the HIV-1 RNA load generally correlated well with HIV gp41 protein load assessed by our immunohistochemical semi-quantitative scoring system. (mahidol.ac.th)
Yet, the local yield a set of mean atomic positions r 0 density, averaged over volume elements of 0.1-1 nm3, varies k r k that define the ``ground-state'' protein structure, or, if resolution permits, a small substantially within a protein (14, 17, 18). (lu.se)
Comparative anatomical distribution of neuronal calcium-binding protein (NECAB) 1 and -2 in rodent and human spinal cord. (scilifelab.se)
Neuronal calcium-binding protein 1 and -2 (NECAB1/2) localize to multiple excitatory neuron populations in the mouse spinal cord. (scilifelab.se)
Interneurons2
Calbindin (red) is predominantly expressed in the dendrites and perikarya of Purkinje cells in the molecular layer of cerebellum (left), and selectively expressed in certain type of interneurons (calbindin-postive interneuron) in the cortex (middle). (biosensis.com)
Myenteric NK 1 R was mainly expressed by intrinsic primary afferent neurons, with minor expression by descending interneurons and inhibitory motor neurons. (nyu.edu)
Immunohistochemistry1
Rat brain cerebellum stained with mouse anti-calbindin (green, 1:1,000) and rabbit anti-calretinin (R-1800-50, red, 1:5,000) by Immunohistochemistry . (biosensis.com)
Serum4
Elevated serum parathyroid hormone and 1,25-dihydroxyvitamin D 3 levels accompanied the enhanced expression of the Ca 2+ transporters. (researchwithrutgers.com)
Intestinal Ca 2+ absorption and expression of calbindin-D 9K and TRPV6, as well as serum parameters of the calbindin-D 28K -/- mice, did not differ from those of wild-type mice. (researchwithrutgers.com)
Description: A sandwich quantitative ELISA assay kit for detection of Rat Calbindin (CALB) in samples from serum, plasma, tissue homogenates or other biological fluids. (clinical-trial-logistics.com)
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Calbindin (CALB) in serum, plasma, tissue homogenates, urine and other biological fluids. (clinical-trial-logistics.com)
These results demonstrate that calbindin and calretinin could be involved in the pathophysiology of skin injury due to exposure to short-wavelength visible light spectrums. (unime.it)
Neurons4
Information regarding the distribution of NK 1 R in subtypes of mouse enteric neurons is lacking and is the focus of the present study. (nyu.edu)
The remaining NK 1 R- immunoreactive neurons were positive for nitric oxide synthase. (nyu.edu)
NK 1 R was expressed by most of the submucosal neurons and was exclusively co-expressed with vasoactive intestinal peptide, with no overlap with choline acetyltransferase. (nyu.edu)
Submucosal NK 1 R was restricted to non-cholinergic secretomotor neurons. (nyu.edu)
Knockout1
For addressing the in vivo role of TRPV5 and calbindin-D 28K in the maintenance of the Ca 2+ balance, single- and double-knockout mice of TRPV5 and calbindin-D 28K (TRPV5 -/- , calbindin-D 28K -/- , and TRPV5 -/- /calbindin-D 28K -/- ) were characterized. (researchwithrutgers.com)
TRPV61
The similarity between TRPV5 -/- /calbindin-D 28K -/- and TRPV5 -/- mice was supported further by an equivalent increase in renal calbindin-D 9K expression and in intestinal Ca 2+ hyperabsorption as a result of upregulation of calbindin-D 9K and TRPV6 expression in the duodenum. (researchwithrutgers.com)
Subunit1
We demonstrate that L-ITCcs are GABAergic, and strongly express metabotropic glutamate receptor 1α and GABA A receptor α1 subunit, together with moderate levels of parvalbumin. (jneurosci.org)
Neuronal2
The distribution of NK 1 R-IR within key functional neuronal subclasses was determined by using established neurochemical markers. (nyu.edu)
These findings highlight key differences in the neuronal distribution of NK 1 R-IR between the mouse, rat and guinea-pig, with important implications for the functional role of NK 1 R in regulating intestinal motility and secretion. (nyu.edu)
Gene2
Kirch, Jennifer Carolin (2022): Trigeminale Afferenzen zu den äußeren Augenmuskeln des Rhesusaffen, die Calbindin, Osteopontin oder Calcitonin-Gene-Related Peptide enthalten. (uni-muenchen.de)
Expression of each cluster's gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq. (stowers.org)
Mice3
D ) Western blots of the cerebellar tissue from mice at different postnatal days (days 1-30). (jci.org)
Urine analysis indicated that TRPV5 -/- / calbindin-D 28K -/- mice exhibit on both diets hypercalciuria compared with wild-type mice. (researchwithrutgers.com)
Ca 2+ excretion in TRPV5 -/- /calbindin-D 28K -/- mice was not significantly different from TRPV5 -/- mice, whereas calbindin-D 28K -/- mice did not show hypercalciuria. (researchwithrutgers.com)
Excretion1
Urine appears to be the major route of excretion, with a urine:fecal ratio of approximately 3:1 in humans. (cdc.gov)
Cerebellum4
E ) Immuno-staining of the adult mouse cerebellum with antibodies against calbindin and Hap1 together or antibodies against Ahi1 and Hap1 together. (jci.org)
Western blot analysis of calbindin expression in cow cerebellum homogenate. (biosensis.com)
Calbindin antibody prominently labels the dendrites and perikarya of Purkinje cells in the molecular layer of cerebellum. (biosensis.com)
Right: Western blot analysis of calbindin expression (antibody dilution: 1:2,000) in rat cerebellum (2), pig hippocampus (3), and cow cerebellum (4). (biosensis.com)
Intestine2
PTH up-regulates the enzyme responsible for 1-alpha hydroxylation of 25-hydroxy vitamin D , converting vitamin D to its active form ( 1,25-dihydroxy vitamin D ). This actived form of vitamin D affects the absorption of calcium (as Ca 2+ ions) by the intestine via calbindin . (bionity.com)
The substance P neurokinin 1 receptor (NK 1 R) regulates motility, secretion, inflammation and pain in the intestine. (nyu.edu)
Tissue2
Our group pioneered the reproducible quantification of HIV-1 RNA in brain tissue homogenates to determine the regional distribution of brain viral loads in AIDS autopsies. (mahidol.ac.th)
Of the truly quantitative techniques, HIV-1 RNA assays of tissue homogenates held the greatest promise for objective cross-study comparisons. (mahidol.ac.th)
Absorption1
1% after 6 hours of exposure, while absorption through scratched and abraded skin was 57% over the same time period (Ilyin et al. (cdc.gov)
Proteins1
In addition, most participants had lower levels of two proteins indicative of brain injury, FABP3 and calbindin D, implying that there was less damage in the brain. (scienceblog.com)
Type2
Developmental and epileptic encephalopathy 1 (DEE1) is a seizure disorder characterized by a type of seizure known as infantile spasms. (medlineplus.gov)
The incidence of both type 2 and type 1 diabetes mellitus has been increasing worldwide. (vitamindwiki.com)
Nephropathy1
β 2 -microglobulin (β 2 -MG) and N -acetyl-β-D-glucosaminidase (NAG) are the dominant biomarkers employed routinely in environmental toxicology research, while kidney injury molecule 1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) are also emerging as effective markers to identify mycotoxin induced nephropathy. (frontiersin.org)
Distribution3
Violin plots show distribution of expression levels for Calbindin-32 (SMED30018274) in cells (dots) of each of the 12 neoblast clusters. (stowers.org)
Violin plots show distribution of expression levels for Calbindin-32 (SMED30018274) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells. (stowers.org)
The distribution of the NK 1 R is a key determinant of the functional effects of substance P in the gut. (nyu.edu)
Human3
Targeting of Calbindin 1 rescues erythropoiesis in a human model of Diamond Blackfan anemia. (bvsalud.org)
Recently, we engineered an R91W;Nrl −/− mouse model 1 to analyze the impact of a human-blinding mutation found in RPE65 (the R91W) specifically on cone photoreceptors. (nature.com)
The circumstances of various famines, plights, and poverty during recent human existence show us this [1-3]. (vitamindwiki.com)
Markers1
In addition to commonly used diagnostic markers for nephrotoxicity including plasma creatinine, NAG, KIM-1 and NGAL can be used in pigs. (frontiersin.org)
Brain1
Immunohistochemical demonstra- inflammation has also been noted in the peripheral nerves tion of viral antigen within the brain and vegetative nerve ( 5 ), myocardium ( 1 , 6 , 7 ), and adrenal glands ( 7 ). (cdc.gov)
Analysis1
NICHD researchers led the design, data collection and analysis of the phase 1/2a clinical trial. (scienceblog.com)
Antibody1
The antibody shows strong immunoractivity with one calbindin band at ~30 kDa. (biosensis.com)
Mouse1
Two mouse brains (1 and 2) at E8, E12, and E18 were examined. (jci.org)
Study1
The study was a phase 1/2a clinical trial designed to test the drug's safety and effectiveness. (scienceblog.com)
Cell3
As a result, double-immunofluorescence shows that calbindin-expressing cell somas appear red, but the nucleus appears to be yellow. (biosensis.com)
Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation. (genscript.com)
Treatment with substance P resulted in the concentration-dependent internalisation of NK 1 R from the cell surface into endosome-like structures. (nyu.edu)
Results1
These results underline the gatekeeper function of TRPV5 being the rate-limiting step in active Ca 2+ reabsorption, unlike calbindin-D 28K , which possibly is compensated by calbindin-D 9K . (researchwithrutgers.com)
Levels1
We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. (stowers.org)
Cells4
However, some cells with a flat appearance were located at this site and were immunonegative for calbindin D-28k. (elsevierpure.com)
We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. (stowers.org)
Expression of Calbindin-32 (SMED30018274) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells. (stowers.org)
Alonso J.R. (1995) Calbindin D-28k and parvalbumin expression in mitotic cells of rat primary cortical cultures. (uv.es)
Proven1
The models, symbols, and prefixes used within the international system are proven in Tables 1, 2, and three. (atpobtvs.com)