• Pharmacological experiments involving the use of apomorphine, amphetamine, phenothiazines, butyrophenones, haloperidol, chlorpromazine, pCPA and LSD 25 have provided evidence for a dopamine (DA)-5-HT interaction. (erowid.org)
  • The antipsychotic agents in clinical use include the phenothiazines and structurally similar compounds such as thioxanthenes, benazepines, butyrophenones, diphenylbutylpiperidines and miscellaneous similar heterocyclic compounds. (nih.gov)
  • Phenothiazines or butyrophenones are known to act at both pre and post-synaptic dopamine receptors, whereas butaclamol or thioxanthenes are supposed to act preferentially at post-synaptic receptors. (erowid.org)
  • Pharmacologic Effect Like the phenothiazines, butyrophenones exert general sympatholytic activity that probably accounts for many of their common properties. (nationalacademies.org)
  • The anticholinergic effect of drugs such as tri- and tetracyclic antidepressants, antihistamines, quinidine, amantadine, antipsychotics (e.g. butyrophenones, phenothiazines), disopyramide and other anticholinergics (e.g. tiotropium, ipratropium, atropine-like compounds) may be intensified by Buscopan. (janusinfo.se)
  • 7.3 Dopamine Antagonists Because ropinirole is a dopamine agonist, it is possible that dopamine antagonists such as neuroleptics (e.g., phenothiazines, butyrophenones, thioxanthenes) or metoclopramide may reduce the efficacy of ropinirole. (feministlawprofessors.com)
  • Haloperidol is a neuroleptic drug that is a member of the butyrophenone group of compounds and may be injected or administered orally. (vin.com)
  • Combinations of concentrations of butyrophenones or control EPI (chlorpromazine) along with ciprofloxacin (CIP) were utilized in checkerboard assays to determine their minimum inhibitory concentration (MIC) and fractional inhibitory concentration (FIC). (confex.com)
  • The atypical antipsychotic risperidone , although not a butyrophenone, was developed with the structures of benperidol and lenperone as a basis. (wikidoc.org)
  • The butyrophenone structure-a ketone flanked by a phenyl ring and a butyl chain-forms the basis for many other chemicals containing various substituents. (wikipedia.org)
  • All together these results show that butyrophenones are inhibitors of the NorA efflux pump , and its derivatives have potential for treating ciprofloxacin resistant S. aureus infections in combination therapy. (confex.com)
  • Other neuroleptics, phenothiazine thioxantene, and butyrophenone derivatives do not affect brain 5-HT levels. (erowid.org)
  • Droperidol, a butyrophenone, is used in many countries to treat agitated or violent patients with acute psychoses but is seldom used in the United States for this purpose following a 2001 black box warning. (medscape.com)
  • Some of these butyrophenones are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics. (wikipedia.org)
  • For all of our butyrophenone compounds we observed a reduction in the MIC of ciprofloxacin in S. aureus 1199B reversing its susceptibility from resistant to susceptible. (confex.com)
  • Domperidone , an dopamine-antagonist antiemetic , derived further from butyrophenone (not being a butyrophenone itself). (wikidoc.org)
  • The butyrophenone domperidone also binds to central dopamine receptors 12 , but it is a very weak antagonist of dopamine-sensitive adenylate cyclase 13 (Table 1), suggesting that it may bind only to D-2 receptors. (nature.com)
  • Butyrophenone selectively extracted Au(III) from many other metals, except for high extraction of Fe(III) and Ga(III) at high concentrations. (go.jp)
  • Au(III) extracted using butyrophenone recovered quantitatively as metallic gold by reduction using oxalic acid. (go.jp)
  • Butyrophenones are a class of pharmaceutical drugs derived from butyrophenone. (wikidoc.org)
  • The MICs for all three butyrophenones, was greater than 200 ug/mL in both strains, demonstrating that on their own, these drugs would be considered non-antibiotics. (confex.com)
  • The efflux assays demonstrated that butyrophenones were able to reduce the loss of ethidium bromide fluorescence over time, confirming a blockage of the NorA efflux pump. (confex.com)
  • α-methylamino-butyrophenone (MABP) is a stimulant research chemical related to methamphetamine that produces euphoriant, and stimulating effects comparable to those of methamphetamine. (1p-lsd-btc.com)
  • In patients experiencing nausea and vomiting despite recommended prophylaxis regimens, ASCO recommends that clinicians consider adding a benzodiazepine (e.g., alprazolam, lorazepam), butyrophenone, or phenothiazine to the regimen or substituting high-dose IV metoclopramide for the 5-HT 3 receptor antagonist in the regimen. (drugs.com)
  • Bromocriptine may interact with dopamine antagonists, butyrophenones, and certain other agents. (com.bd)
  • Butyrophenone is an organic compound with the formula C6H5C(O)C3H7. (wikipedia.org)