• 0.05
  • A definite dosage-response relationship was detected in that butorphanol dosage of 0.1 mg/kg was more effective than 0.05 mg/kg but not different from 0.2 mg/kg in alleviating deep abdominal pain. (drugs.com)
  • RR (from 11 ± 3 to 8 ± 3 mpm) and pH (from 7.28 ± 0.05 to 7.25 ± 0.05) decreased after butorphanol administration while PaCO2 increased significantly (from 49.9 ± 5 to 58.5 ± 6 mmHg). (vin.com)
  • dosage
  • 1 Furthermore, the cardiopulmonary effects of butorphanol are not distinctly dosage-related but rather reach a ceiling effect beyond which further dosage increases result in relatively lesser effects. (drugs.com)
  • Rapid intravenous administration of butorphanol at a dosage of 2 mg/kg (20 times the recommended dosage) to a previously unmedicated horse resulted in a brief episode of inability to stand, muscle fasciculation, a convulsive seizure of 6 seconds duration and recovery within three minutes. (drugs.com)
  • The same dosage administered after 10 successive daily 1 mg/kg dosages of butorphanol resulted only in transient sedative effects. (drugs.com)
  • substance
  • With the issuance of this final rule, the Acting Deputy Administrator of the Drug Enforcement Administration (DEA) places the substance butorphanol, including its salts and optical isomers, into Schedule IV of the Controlled Substances Act (CSA). (usdoj.gov)
  • Correspondence from the Acting Assistant Secretary for Health dated June 19, 1997, confirmed that the DHHS recommendation included the substance butorphanol and its salts and isomers. (usdoj.gov)
  • Butorphanol is a prohibited substance and a prohibited class A medication in competitions. (equimed.com)
  • morphine
  • In animals, butorphanol has been demonstrated to be 4 to 30 times more potent than morphine and pentazocine (Talwin ® -V) respectively. (drugs.com)
  • 1 In humans, butorphanol has been shown to have 5-7 times the analgesic activity of morphine and 20 times that of pentazocine. (drugs.com)
  • significantly
  • Administered by professionals as part of a long-term drug-addiction recovery strategy, The RDD Method ® is significantly more effective than other courses of Butorphanol addiction treatment. (rapiddrugdetox.com)
  • After butorphanol administration the haemodynamic variables decreased significantly, accordingly to the statistical test used: HR (from 138 ± 21 to 118 ± 19 bpm), MAP (from 86 ± 10 to 63 ± 10 mmHg), MPAP (from 10 ± 3 to 7 ± 3 mmHg), SVR (from 2954 ± 585 to 2207 ± 626 dynes*sec*cm-5) and LVW (from 2.8 ± 0.8 to 1.9 ± 0.9 Kg*m*min-1). (vin.com)
  • administration
  • The aim of this study was to evaluate the hemodynamics and respiratory alterations due to butorphanol administration in desflurane anesthetized dogs. (vin.com)
  • The results allowed to conclude that although butorphanol administration in desflurane anesthetized dogs produced reduction in the averages of the mean arterial pressure and mean pulmonary artery pressure, as well as in the left ventricle work, it didn't determine significant alterations in CO, SV and CVP. (vin.com)
  • products
  • As a result of this rule, the regulatory controls and criminal sanctions of Schedule IV will be applicable to the manufacture, distribution, dispensing, importation and exportation of butorphanol and products containing butorphanol. (usdoj.gov)
  • dogs
  • 2,3 Butorphanol has 15 to 20 times the oral antitussive activity of codeine or dextromethorphan in dogs and guinea pigs. (drugs.com)
  • abuse
  • It was determined that butorphanol, whether administered orally, intravenously, or intranasally, had an abuse potential consistent with control in Schedule IV of the CSA. (usdoj.gov)
  • patient
  • Read the Medication Guide and the Patient Information Leaflet provided by your pharmacist before you start using butorphanol and each time you get a refill. (medicinenet.com)