• Bromodeoxyuridine (5-bromo-2'-deoxyuridine, BrdU, BUdR, BrdUrd, broxuridine) is a synthetic nucleoside analogue with a chemical structure similar to thymidine. (wikipedia.org)
  • Are there any alternatives to BrdU (Bromodeoxyuridine)? (aatbio.com)
  • Yes, there are alternatives to BrdU (Bromodeoxyuridine) that can be used in cell proliferation assays. (aatbio.com)
  • Active microorganisms have been identified previously using stable isotope probing (SIP) or bromodeoxyuridine (BrdU) labeling. (nature.com)
  • Twelve piglets per group were slaughtered at 5, 12 and 26 dpn, one hour after injection with Bromodeoxyuridine (BrdU, 12 mg/kg). (nature.com)
  • Bromodeoxyuridine (BrdU) immunocytochemistry and flow cytometry were applied to detect the proliferation of VSMCs. (hindawi.com)
  • The lungs were examined following a single injection of bromodeoxyuridine (BrdU) 2 h prior to necropsy. (cdc.gov)
  • Bromodeoxyuridine (BrdU) is a synthetic analogue of thymidine, one of the building blocks of DNA. (vetscite.org)
  • to OECD TG 442B and GLP, the skin sensitising potential of 2-ethoxyethyl (2Z)-2-cyano-2-[3-(3-methoxypropylamino)cyclohex-2-en-1-ylidene]acetate (C-1701 B_C_3) in female CBA/J mice was evaluated using the non-radioactive local lymph node assay (Ina Research Inc. (2012), 58V0473111X188), which assess BrdU incorporation as a measure of lymphocyte proliferation. (europa.eu)
  • On day 5, Bromodeoxyuridine (BrdU) was administered intraperitoneally (i.p.) to all animals at a dose level of 5 mg/animal. (europa.eu)
  • Bromodeoxyuridine (BrdU) incorporation assay and migration studies were performed to elucidate antiproliferative activity of the drug, if any. (jcimjournal.com)
  • Agyrophilic nucleolar organizer region counts as related to bromodeoxyuridine incorporation scores in ovarian clear cell carcinoma cells]. (bvsalud.org)
  • Synchronized hepatoma tissue culture (HTC) cells, accumulated at the G1/S boundary with aminopterin, were released into S phase with either thymidine or 5-bromodeoxyuridine (BUdR). (rupress.org)
  • However, no significant correlation was obtained between the number of Ag-NORs and the bromodeoxyuridine-labeling indices (r =0.2064). (karger.com)
  • Bromodeoxyuridine (BUdR), a potential radiosensitizing drug, was given by intravenous infusion at 650-1000 mg/m2/day for up to 12 days. (tmu.edu.tw)
  • Replication not inhibited by 5-bromodeoxyuridine. (cdc.gov)
  • The kinetics of replication and transcription (monitored by immunolabelling after incorporating bromodeoxyuridine or bromouridine) reveal that each genome replicates independently of others in a focus, and that newly-made RNA remains in a focus (residence half-time ~43 min) long after it has been made. (biomedcentral.com)
  • Tyrosine aminotransferase sensitivity to bromodeoxyuridine during restricted intervals of S phase in hepatoma cells. (rupress.org)
  • En face co-immunostaining of the mouse aortic arch revealed a low level of PDCD4 in endothelial cells undergoing pulsatile shear stress. (plos.org)
  • 0.05) increased numbers of bromodeoxyuridine-immunoreactive cells in the subventricular zone and the dentate gyrus and numbers of immature neurons, as indicated by betaIII-tubulin (TuJ1) immunoreactivity in the ipsilateral subventricular zone and striatum. (nih.gov)
  • In our article in BMC Cancer [ 1 ] we modelled our graph for the passage of bromodeoxyuridine-labelled cells through the cell cycle presented in Figure 1 on the figure published by Johansson et al. (biomedcentral.com)
  • Johansson MC, Baldetorp B, Bendahl PO, Johansson R, Oredsson SM: An improved mathematical method to estimate DNA synthesis time of bromodeoxyuridine-labelled cells, using FCM-derived data. (biomedcentral.com)
  • 13. Newmark P.A., Sanchez Alvarado A. (2000) Bromodeoxyuridine specifically labels the regenerative stem cells of planarians. (medline.ru)
  • Eidukevicius R, Characiejus D, Janavicius R, Kazlauskaite N, Pasukoniene V, Mauricas M, Den Otter W: A method to estimate cell cycle time and growth fraction using bromodeoxyuridine-flow cytometry data from a single sample. (biomedcentral.com)
  • Based on the study results, 2-ethoxyethyl (2Z)-2-cyano-2-[3-(3-methoxypropylamino)cyclohex-2-en-1-ylidene]acetate (C-1701 B_C_3) was considered not to possess any skin sensitising potential under the experimental conditions employed. (europa.eu)
  • We investigated the effects of DNA secondary structure and O 2 on the induction of direct strand breaks in 5-bromodeoxyuridine-containing oligonucleotides. (nau.edu)
  • In vivo evaluation by bromodeoxyuridine incorporation and flow cytometry. (nih.gov)
  • The effect of lycopene-based agents on prostate cancer growth and survival were examined using proliferation assays, bromodeoxyuridine incorporation and flow cytometric analysis of cellular DNA content. (nih.gov)
  • Daily lymphocyte production in both central and peripheral lymphoid organs was evaluated by associating in vivo incorporation of bromodeoxyuridine (BrdUrd) with cell surface labeling and multi-parameter flow analysis. (pasteur.fr)
  • 4. Cell kinetics of human ovarian cancer with in vivo administration of bromodeoxyuridine. (nih.gov)
  • 10. Combined flow cytometry and immunohistochemistry analyses for the assessment of nasopharyngeal carcinoma cell kinetics by in vivo bromodeoxyuridine infusion. (nih.gov)
  • In vivo bromodeoxyuridine incorporation in normal mouse kidney: immunohistochemical detection and measurement of labeling indices. (bdbiosciences.com)
  • Dover R, and Patel K. Improved methodology for detecting bromodeoxyuridine in cultured cells and tissue sections by immunocytochemistry. (bdbiosciences.com)
  • Flow cytometric measurement of total DNA content and incorporated bromodeoxyuridine. (bdbiosciences.com)
  • Bromodeoxyuridine releases gene silencing caused by DNA methylation. (wikipedia.org)
  • Replication not inhibited by 5-bromodeoxyuridine. (cdc.gov)