• Organisms that are most frequently associated with brain abscess in patients with AIDS are poliovirus, Toxoplasma gondii, and Cryptococcus neoformans, though in infection with the latter organism, symptoms of meningitis generally predominate. (wikipedia.org)
  • Intracranial abscesses can originate from infection of contiguous structures (eg, otitis media , dental infection, mastoiditis, sinusitis) secondary to hematogenous spread from a remote site (especially in patients with cyanotic congenital heart disease), after skull trauma or surgery, and, rarely, following meningitis . (medscape.com)
  • CNS manifestations of listerosis depend on the affected intracranial compartment and include meningitis, encephalitis, rhombencephalitis, meningoencephalitis and less commonly cerebral abscess. (eurorad.org)
  • Acute Bacterial Meningitis Acute bacterial meningitis is rapidly developing inflammation of the layers of tissue that cover the brain and spinal cord (meninges) and of the fluid-filled space between the meninges (subarachnoid. (merckmanuals.com)
  • Because meningitis is now uncommon in children, epidural abscesses and subdural empyemas are also uncommon in children. (merckmanuals.com)
  • Meningitis or a brain abscess may develop. (merckmanuals.com)
  • Meningitis rarely results in brain abscess by direct extension, particularly in adults, and therefore in most cases the finding of brain abscess should not prompt a search for meningeal infection via lumbar puncture. (medscape.com)
  • Here we report a case of brain abscess caused by Salmonella enterica serovar Enteritidis mimicking post-surgical meningitis in a patient with glioblastoma multiforme. (biomedcentral.com)
  • In this case report, a brain abscess was initially diagnosed as Salmonella post-surgical meningitis before the imaging diagnosis of the brain abscess. (biomedcentral.com)
  • The diagnosis of brain abscess should be considered in all cases of non-typhoidal Salmonella meningitis after surgery for brain tumor. (biomedcentral.com)
  • Combining Ceftriaxone with Doxycycline and Daptomycin Reduces Mortality, Neuroinflammation, Brain Damage, and Hearing Loss in Infant Rat Pneumococcal Meningitis. (escmid.org)
  • Both encephalitis and meningitis are severe illnesses caused due to viral or bacterial infection and result in the inflammation of the brain. (differencebetween.net)
  • Meningeal infections, which affect the protective layers (cellular tissues) that encircle the brain and spinal cord, frequently result in meningitis. (differencebetween.net)
  • The infection of the meninges (three layers of membranes that cover and protect your brain and spinal cord) is known as meningitis. (differencebetween.net)
  • Meningitis is an inflammation of the meninges (which protects the nervous system), the protective layer surrounding the brain and spinal cord. (differencebetween.net)
  • Encephalitis is an infection of the entire brain tissue, whereas meningitis is an inflammation of the (protective membranes of the brain and the spiral cord) meninges. (differencebetween.net)
  • What is the difference between meningitis encephalitis and brain abscess? (differencebetween.net)
  • Brain abscess (or cerebral abscess) is an abscess within the brain tissue caused by inflammation and collection of infected material coming from local (ear infection, dental abscess, infection of paranasal sinuses, infection of the mastoid air cells of the temporal bone, epidural abscess) or remote (lung, heart, kidney etc.) infectious sources. (wikipedia.org)
  • These symptoms are caused by a combination of increased intracranial pressure due to a space-occupying lesion (headache, vomiting, confusion, coma), infection (fever, fatigue etc.) and focal neurologic brain tissue damage (hemiparesis, aphasia etc. (wikipedia.org)
  • The case of a Ugandan child with a polymicrobial brain abscess including infection with Tissierella praeacuta / Clostridium hastiforme requiring repeated drainage and eventual surgical excision is reported. (hindawi.com)
  • Invasive infection is very rare in humans, and most were observed in immunocompromised patients, manifesting as osteomyelitis ( 3 , 4 ) or diffuse vascular brain invasion ( 5 ). (cdc.gov)
  • An abscess may form in the brain when bacteria from an infection elsewhere in the head or in the bloodstream or from a wound enter the brain. (merckmanuals.com)
  • Brain abscess is caused due to bacterial infection in the brain. (yashodahospitals.com)
  • The infection in the brain may be due to infections in other parts of the body viz. (yashodahospitals.com)
  • However, brain abscess may occur due to infection of the skull, through the blood stream and head injury. (yashodahospitals.com)
  • Brain abscess es are suppurative infection s of the brain parenchyma surrounded by a vascularized capsule . (neurosurgery.directory)
  • Initial parenchymal infection is known as cerebritis, which may progress into a cerebral abscess. (neurosurgery.directory)
  • Brain abscess is a focal intracranial infection that may present as a life-threatening emergency. (medscape.com)
  • improvements in the detection and treatment of ear, sinus, and orofacial infections has decreased the incidence of brain abscess as a consequence of direct spread of infection. (medscape.com)
  • The pathogenesis of an invading organism that has inoculated the brain parenchyma is variable and dependent on the initial site of infection, host factors, and geographic location. (medscape.com)
  • Brain abscess may be caused by the contiguous spread of pathogens from a primary focus of infection outside of the CNS that extends into the brain. (medscape.com)
  • An abscess on the brain is a collection of pus that forms due to an infection or trauma. (brainandspinespecialist.com)
  • A bacterial or fungal infection in the brain is the most common cause of a brain abscess. (brainandspinespecialist.com)
  • Invasive Salmonella infections have been reported due to their potential to cause focal suppurative complications in urinary tract infection, osteoarticular infection and liver abscess [ 1 ]. (biomedcentral.com)
  • A tooth abscess is a pocket of pus caused by a bacterial infection. (adam.com)
  • If you have a severe infection, your tooth may need to be removed, or you may need surgery to drain the abscess. (adam.com)
  • A brain abscess is a collection of pus, immune cells, and other material in the brain, caused by a bacterial or fungal infection. (adam.com)
  • Brain biopsy showed Entamoeba histolytica infection. (aku.edu)
  • A brain abscess is a focal infection characterized by a collection of pus in the brain parenchyma. (bvsalud.org)
  • We describe a case of brain abscess secondary to a pulmonary infection in an elderly, diabetic, Afghani man with an extensive history of chewing tobacco use. (kabbesh.com)
  • While this immune response can protect the brain by isolating the infection, it can also do more harm than good. (geometry.net)
  • Oral pathogens from an odontogenic infection may enter the brain via a hematologic or lymphatic route, or by direct extension through the fascial planes. (bvsalud.org)
  • The treatment of abscesses of the central nervous system (CNS) is based on three main points: clinical treatment with antibiotics, neurosurgical treatment of the abscess using a method appropriate to the case, and treatment of the primary focus of infection. (bvsalud.org)
  • Brain abscess is caused by intracranial inflammation with subsequent abscess formation. (medscape.com)
  • [ 5 , 6 ] The process begins with direct inoculation of microorganisms into the brain parenchyma, resulting in focal inflammation in the 1-3 days following, which is referred to as early cerebritis. (medscape.com)
  • An abscess forms when an area of cerebral inflammation becomes necrotic and encapsulated by glial cells and fibroblasts. (msdmanuals.com)
  • Inflammation and swelling occur when bacteria, fungi, or parasites infect a portion of the brain. (brainandspinespecialist.com)
  • The brain swells in response to the inflammation, and the mass may put pressure on delicate brain tissue. (geometry.net)
  • On the other side, encephalitis occurs due to the swelling (inflammation) of the entire brain. (differencebetween.net)
  • Brain inflammation known as encephalitis can be brought on by a virus, bacteria, medicine, or immune system problem. (differencebetween.net)
  • Encephalitis is a rare but serious condition that causes inflammation of the brain itself. (differencebetween.net)
  • Intracranial abscesses are uncommon, serious, life-threatening infections. (medscape.com)
  • Direct extension usually causes a single brain abscess and may occur from necrotic areas of osteomyelitis in the posterior wall of the frontal sinus, the sphenoid and ethmoid sinuses, mandibular dental infections, as well as from subacute and chronic otitis media and mastoiditis. (medscape.com)
  • The frequency of brain abscesses resulting from ear infections has declined in developed countries. (medscape.com)
  • [ 1 ] Pediatric bacterial brain abscesses, epidural empyemas, and subdural empyemas, rare complications of respiratory infections and sinusitis, are often caused by Streptococcus species but might also be polymicrobial or caused by other genera, such as Staphylococcus . (medscape.com)
  • Discussions with clinicians in multiple states raised concerns (intracranial abscess and granuloma) or G06.2 (extradural and about a possible increase in pediatric intracranial infections, subdural abscess, unspecified) during the study period were particularly those caused by Streptococcus bacteria, during the included. (cdc.gov)
  • Brain abscesses are rare and account for 1-10% of CNS listerial infections (4,5). (eurorad.org)
  • Majorly, the heart and lung infections are considered to cause brain abscess. (yashodahospitals.com)
  • The brain is protected from all infections. (yashodahospitals.com)
  • Brain abscess occurs as the result of a complication of variety of infections, trauma, or surgery and carries significant morbidity and mortality. (medscape.com)
  • [ 12 ] Dental infections can lead to brain abscess via either contiguous or hematogenous routes. (medscape.com)
  • Severe invasive infections such as brain abscess in a child should prompt an immune evaluation. (johnshopkins.edu)
  • But poor dental hygiene and tooth abscess can increase your risk for lung infections caused by these bacteria. (medlineplus.gov)
  • In the postgraduate education course "acute bacterial CNS infections of the brain", the first focus will be on the diagnostic work-up of patients with suspected CNS infections. (escmid.org)
  • Nocardia are non-motile, Gram-positive, partially acid-fast bacilli, most commonly responsible for lung, brain, and skin infections in immunocompromised hosts including those with acquired immunodeficiency syndrome (AIDS), cancer, lupus, and diabetes. (kabbesh.com)
  • Ear and sinus infections may also spread directly to the brain because of their close proximity. (geometry.net)
  • Diagnosis: Cerebral abscess Discussion: Between (30% and 60%) of pyogenic abscesses are mixed infections, with aerobic isolates outnumbering anaerobic isolates approximately 2 to 1. (geometry.net)
  • A circumscribed collection of purulent exudate in the brain, due to bacterial and other infections. (bvsalud.org)
  • Brain abscess may result in severe complications viz. (yashodahospitals.com)
  • Untreated abscesses may get worse and can lead to life-threatening complications. (adam.com)
  • Complications like brain abscess always remain a danger. (ispub.com)
  • A computer-guided needle-aspiration of the brain lesions yielded yellow-brown, creamy fluid in which abundant septated fungal hyphae were detected microscopically ( Figure C). Cytologic investigation was consistent with a necrotic abscess. (cdc.gov)
  • To determine the demographics, management, and the variables that affect the outcome in subjects with brain abscesses treated at a single centre over an 11-year period, we retrospectively analysed data in 60 patients with brain abscesses surgically treated with stereotactically guided aspiration or open craniotomy excision in Shanghai Changzheng Hospital between January 2001 and December 2011. (biomedcentral.com)
  • Stereotactically guided aspiration is an effective treatment for brain abscess with an overall favourable outcome. (biomedcentral.com)
  • Two primary treatments are used to manage brain abscesses: stereotactically guided aspiration and open craniotomy excision. (biomedcentral.com)
  • Despite the advent of modern neurosurgical techniques, including stereotactic brain biopsy and aspiration, better culturing techniques to identify the infectious agent, new antibiotics, and modern non-invasive neuroimaging procedures, brain abscess still poses a public health challenge, especially in developing countries. (biomedcentral.com)
  • To reduce operative and anesthetic risk in these patients, abscesses should be managed by less invasive aspiration methods guided by computed tomography. (neurosurgery.directory)
  • A CT-guided stereotactic aspiration of brain abscess was performed in a series of 15 patients, of which 12 patients had single abscess formation while 3 patients had multiple brain abscess. (tmu.edu.tw)
  • Thus stereotactic aspiration appears to be a safe and effective method for the treatment of brain abscess. (tmu.edu.tw)
  • Methods: Fifty-one patients with brain abscesses who underwent navigation-assisted abscess aspiration with antibiotic treatment were included in this study. (korea.ac.kr)
  • Many brain abscesses are polymicrobial. (wikipedia.org)
  • We report here three cases of patients with otogenic brain abscesses of polymicrobial origin that had in common the isolation of Actinomyces europaeus, which has not been previously described in this location . (bvsalud.org)
  • Here, we report a case of brain abscess caused by S. enterica subspecies (subsp. (biomedcentral.com)
  • Hematogenous seeding of the brain from an extracranial source is the second most common etiology of brain abscess, accounting for approximately 25% of cases. (medscape.com)
  • One trend is that there appears to be a trend toward a decreasing incidence of brain abscess. (neurosurgery.directory)
  • Dr. Nitin Jagdhane is one of the best Neurosurgeon and Spine specialists for an accurate diagnosis and treatment of brain abscess in Mumbai, India. (brainandspinespecialist.com)
  • Brain Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) were performed. (eurorad.org)
  • Abscesses larger than 2 cm in diameter, in deep-located or parieto-occipital regions, should be aspirated immediately and repeatedly, mainly using computed tomography-guided methods to decrease intracranial pressure and avoid IVROBA. (neurosurgery.directory)
  • Brain computed tomography revealed a large cerebral abscess located at the operative site. (biomedcentral.com)
  • They include brain abscess and subdural or extradural empyema and are classified according to the anatomical location or the etiologic agent. (medscape.com)
  • A brain abscess is an intracerebral collection of pus. (msdmanuals.com)
  • The term brain abscess is used in this article to represent all types of intracranial abscesses. (medscape.com)
  • Mortality due to brain abscess was not directly related to surgery nor surgical technique. (biomedcentral.com)
  • What are the operations/ surgical treatments available for Brain abscess? (brainandspinespecialist.com)
  • Surgical drainage of the abscess was performed and microbial cultures of surgical deep samples were positive for the same S. enterica Enteritidis isolate. (biomedcentral.com)
  • Surgical brain abscess drainage followed by prolonged antibiotic treatment remains a major therapeutic option. (biomedcentral.com)
  • Brain abscesses commonly occur when bacteria or fungi infect part of the brain. (geometry.net)
  • All inpatient encounters from patients aged ≤18 years with a primary or secondary discharge diagnosis of International Classification of Diseases, Tenth Revision, Clinical Modification code G06.0 (intracranial abscess and granuloma) or G06.2 (extradural and subdural abscess, unspecified) during the study period were included. (medscape.com)
  • In CDC's national call for cases, a case was defined as the diagnosis of brain abscess, epidural empyema, or subdural empyema in a person aged ≤18 years without a previous neurosurgical procedure or history of head trauma, hospitalized on or after June 1, 2021, irrespective of etiology. (medscape.com)
  • In May 2022, CDC learned of three children in California encounters from patients aged 18 years with a primary or hospitalized concurrently for brain abscess, epidural empyema, secondary discharge diagnosis of International Classification or subdural empyema caused by Streptococcus intermedius . (cdc.gov)
  • Pediatric bacterial brain abscesses, epidural empy- codes U07.1 or B97.29 on the discharge diagnosis list. (cdc.gov)
  • On June 9, CDC asked clini- diagnosis of brain abscess, epidural empyema, or subdural cians and health departments to report possible cases of these empyema in a person aged 18 years without a previous neu- conditions and to submit clinical specimens for laboratory rosurgical procedure or history of head trauma, hospitalized testing. (cdc.gov)
  • see Brain abscess diagnosis . (neurosurgery.directory)
  • Significant advances in the diagnosis and management of bacterial brain abscess over the past several decades have improved the expected outcome of a disease once regarded as invariably fatal. (neurosurgery.directory)
  • Diagnosis Intracranial tumors may involve the brain or other structures (eg, cranial nerves, meninges). (msdmanuals.com)
  • Diagnosis Ischemic stroke is sudden neurologic deficits that result from focal cerebral ischemia associated with permanent brain infarction (eg, positive results on diffusion-weighted MRI). (msdmanuals.com)
  • How is the diagnosis of Brain Abscess done? (brainandspinespecialist.com)
  • Click on Images for Enlarged View Diagnosis cerebral abscess. (geometry.net)
  • We analysed the prognostic factors and strategies of treatment to look for trends in occurrence, prognosis, predisposing risk factors, and infectious agent in brain abscesses. (biomedcentral.com)
  • Multicenter prospective studies and randomized clinical trials are needed to further advance treatment and prognosis in brain abscess patients. (neurosurgery.directory)
  • Prognosis has improved over time, likely due to improved brain imaging techniques, minimally invasive neurosurgical procedures, and protocoled antibiotic treatment 5) . (neurosurgery.directory)
  • The video shows an surgery in which pus is suctioned from the brain cavity. (gorecenter.com)
  • After the operation, brain CT scans revealed immediate shrinkage of the abscess cavity and gradual disappearance of the enhanced ring. (tmu.edu.tw)
  • Right fronto-parietal craniotomy was performed by the neurosurgeon and an encapsulated abscess cavity was drained and completely removed. (ispub.com)
  • A tooth abscess may form if there is tooth decay . (adam.com)
  • Prompt treatment of dental decay reduces the risk of developing a tooth abscess. (adam.com)
  • If there are multiple abscesses, it may be too dangerous to remove them all. (brainandspinespecialist.com)
  • Mortality was significantly associated with increasing age, multiple abscesses, immunosuppression and the presence of an underlying cardiac anomaly. (ox.ac.uk)
  • Pathogens may originate from adjacent bone, teeth, sinus mucosa, internal auditory canal, or cochlear structures and travel into the intracranial vault via venous drainage or valveless emissary veins, thus inoculating the brain parenchyma. (medscape.com)
  • The inflammatory reaction causes encephalitis if they manage to enter the brain parenchyma itself. (differencebetween.net)
  • 90% of brain abscesses in immunocompromised transplant patients with an associated mortality rate of 97% ( 10 ), despite aggressive surgery and antifungal therapy ( 9 ). (cdc.gov)
  • BACKGROUND: Brain abscess is an uncommon condition, but carries high mortality. (ox.ac.uk)
  • Long-term mortality and epilepsy in patients after brain abscess: A nationwide population-based matched cohort study. (escmid.org)
  • There has been a gradual improvement in the outcome of patients with brain abscess over the past 50 years, which might be driven by improved brain imaging techniques, minimally invasive neurosurgical procedures, and protocoled antibiotic treatment. (neurosurgery.directory)
  • In May 2022, CDC learned of three children in California hospitalized concurrently for brain abscess, epidural empyema, or subdural empyema caused by Streptococcus intermedius . (medscape.com)
  • Available Streptococcus specimens isolated from a brain abscess, pandemic in March 2020, increased during summer 2021 to epidural empyema, subdural empyema, blood, or cerebrospinal a peak in March 2022, and then declined to baseline levels. (cdc.gov)
  • He was first diagnosed with lung cancer in August 2020, but only publicly shared the news in November 2022 after the cancer spread to his brain. (yahoo.com)
  • Available Streptococcus specimens isolated from a brain abscess, epidural empyema, subdural empyema, blood, or cerebrospinal fluid were collected for antimicrobial susceptibility testing and whole-genome sequencing at CDC's Streptococcus reference laboratory to identify microbiological features shared among cases. (medscape.com)
  • In a article, Chen review the literature to find out how the epidemiology of this disease has changed through the years and re-visit the basic pathological process of abscess evolution and highlight the new research in the biochemical pathways that initiate and regulate this process 1) . (neurosurgery.directory)
  • There have been several trends in the epidemiology of brain abscess over recent decades. (neurosurgery.directory)
  • Brain abscess is usually associated with congenital heart disease in young children. (wikipedia.org)
  • Other possible causes for brain abscess are congenital heart disease, pulmonary arteriovenous fistula, dental abscess or tooth decay, pneumonia, endocarditis, peritonitis and cystitis. (yashodahospitals.com)
  • Through collaboration with the Children's Hospital Association (CHA), CDC analyzed nationally representative pediatric hospitalizations for brain abscess and empyema. (medscape.com)
  • The call for Association (CHA), CDC analyzed nationally representative cases was shared with health departments and two provider list- pediatric hospitalizations for brain abscess and empyema. (cdc.gov)
  • However, abscesses complicating sinusitis has not decreased in frequency. (medscape.com)
  • Magnetic resonance imaging (MRI) of the brain disclosed 2 masses, 3.3 and 4.8 cm in diameter, respectively ( Figure A), and signs of chronic sinusitis. (cdc.gov)
  • Although less common, brain abscess has been described as a complication of frontal, ethmoidal, or sphenoidal sinusitis. (medscape.com)
  • Brain MRI showed two lesions located on the left cerebellar peduncle (Fig 2A) and on the left frontal lobe (Fig 2B). (eurorad.org)
  • Brain CT revealed a nonspecific hypodense lesion of the left frontal lobe (Fig 1). (eurorad.org)
  • Most of the abscesses were solitary frontal or parietal lesions. (ox.ac.uk)
  • Brain magnetic resonance imaging showed a mass in the left frontal lobe, while abdominal computerized tomography showed a left renal malignancy. (aku.edu)
  • female patients and patients greater than 40 years of age were most likely to suffer a brain abscess. (biomedcentral.com)
  • Additional studies will continue to reveal patients trends that may improve treatment for brain abscess. (biomedcentral.com)
  • This report is based on our experience with 82 brain abscesses surgically managed in 60 patients over an 11-year period at one single hospital. (biomedcentral.com)
  • Sixty patients with a total of 82 brain abscesses verified by postoperative pathology were treated surgically between January 2001 and December 2011 at the department of Neurosurgery in Shanghai Changzheng Hospital. (biomedcentral.com)
  • Patients were excluded from the study if, 1) there was evidence of neurological symptoms unrelated to brain abscess, 2) there was evidence showing the patient had not undergone a drainage procedure or intraoperative pus sampling, or 3) the patient was lost to follow-up during the study period. (biomedcentral.com)
  • particularly in HIV-infected patients) can cause abscesses. (msdmanuals.com)
  • We also review cases of Salmonella brain abscess in patients with cerebral tumors. (biomedcentral.com)
  • is a cause of brain abscesses in patients with underlying pulmonary structural disease like bronchiectasis. (archivosdeneurociencias.org)
  • METHODS: We undertook a retrospective, observational study of patients with brain abscess, based on hospital coding, in a UK tertiary referral teaching hospital. (ox.ac.uk)
  • Objective: The purpose of this study was to describe the clinical characteristics, treatment outcomes, and prognostic factors in patients with brain abscesses treated in a single institute during a recent 10-year period. (korea.ac.kr)
  • Conclusion: We found that the level of consciousness at admission was associated with treatment outcomes in patients with brain abscesses. (korea.ac.kr)
  • In neutropenic patients, brain abscesses may be caused by candida or aspergillus. (geometry.net)
  • A high index of suspicion is essential in susceptible patients presenting with pulmonary infiltrate, cerebral abscess or deep soft-tissue abscess and usually requires an active diagnostic workup and early administration of appropriate therapy. (who.int)
  • At least 3 different pathways have been suggested for CNS invasion: 1) through the blood-brain and blood-choroid barriers, within infected phagocytes, 2) direct invasion of the capillary endothelium by the circulating extracellular bacteria, 3) retrograde migration into the CNS, by travelling through the axons of cranial nerves and especially along trigerminal nerve (7). (eurorad.org)
  • Brain abscess may rupture inside the skull due to gasses produced by the bacteria. (yashodahospitals.com)
  • CNS abscess A brain abscess is a mass of immune cells, pus, and other material that can occur when the brain is infected by bacteria or fungus. (geometry.net)
  • It is also important to note that the immune status of the patient can influence the organism causing the abscess. (geometry.net)
  • These abscesses are more commonly multiple and multiloculated and are frequently found in the distribution of the middle cerebral artery. (medscape.com)
  • Meanwhile, the population prevalence of chronic immune suppression and immunocompromise has grown, and with it there has been a rise in opportunistic and fungal brain abscess. (medscape.com)
  • The prevalence of brain abscesses in young children has decreased as a result of vaccination campaigns. (brainandspinespecialist.com)
  • Amoebic brain abscess associated with renal cell carcinoma" by Umme Hani Abdullah,, Mirza Zain Baig, et al. (aku.edu)
  • We report a case of amoebic brain abscess in a man who presented with fever, vomiting and headache with confusion and right hemiparesis. (aku.edu)
  • cerebral abscess Looks at the common causes,bacterial aetiology, pathology, clinical presentation and treatment. (geometry.net)
  • Trauma that causes an open skull fracture allows organisms to seed directly in the brain. (medscape.com)
  • CDC will continue to work with investigation partners to monitor ongoing trends in pediatric brain abscesses and empyemas. (medscape.com)
  • Two data sources were analyzed: 1) pediatric hospitalizations for brain abscesses, epidural empyemas, and subdural empyemas reported to CHA's Pediatric Health Information System (PHIS) and 2) cases reported to CDC in response to a national call for cases. (medscape.com)
  • 6 ). The agar diffusion gradient method (Etest, bioMérieux) brain abscesses and empyemas. (cdc.gov)