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  • vivo
  • To figure out if IL-6 is a element implicated in the ex vivo bone marrow amplification noticed in the existence of PTH and Flt-3L, bone marrow cells had been cultured for 8 times with a single remedy of PTH, Flt-3L or PTH plus Flt-3L in the existence and absence of IL-6 at the time of plating. (c14-demethylase.com)
  • diagnosis
  • Calcium elevation, renal injury, anemia, and bone lesions (CRAB features) are needed for establishing the diagnosis of active myeloma. (kjco.org)
  • Analysis
  • The aspirate yields semi-liquid bone marrow, which can be examined by a pathologist under a light microscope and analyzed by flow cytometry, chromosome analysis, or polymerase chain reaction (PCR). (wikipedia.org)
  • human bone
  • The chapter examines pathologic findings seen in the human bone marrow. (springer.com)
  • In-vitro colony forming cell (CFC) assays using normal human bone marrow grown in appropriate semi-solid media such as ColonyGEL have been shown to be useful in predicting the level of clinical myelotoxicity a certain compound might cause if administered to humans. (wikipedia.org)
  • patients
  • In immunocompromised patients, B19 infection may persist for months, leading to chronic anemia with B19 viremia due to chronic marrow suppression. (wikipedia.org)
  • progenitor
  • These predictive in-vitro assays reveal effects the administered compounds have on the bone marrow progenitor cells that produce the various mature cells in the blood and can be used to test the effects of single drugs or the effects of drugs administered in combination with others. (wikipedia.org)
  • tibia
  • In some restaurants, cooked pig tibia would be served with a drinking straw specifically for sucking out the semi-liquified marrow. (wikipedia.org)
  • chemotherapy
  • Bone marrow is suppressed with the use of cancer chemotherapy. (news-medical.net)
  • Bone marrow suppression due to anti-cancer chemotherapy is much harder to treat and often involves hospital admission, strict infection control, and aggressive use of intravenous antibiotics at the first sign of infection. (wikipedia.org)
  • aplastic
  • A leading contributor to bone marrow failure disorder registries, including the International Fanconi Anemia Registry, Diamond-Blackfan Registry, Shwachman- Diamond Registry and North American Pediatric Aplastic Anemia Consortium (NAPAAC). (childrens.com)
  • Aplastic anemia happens when bone marrow doesn't produce enough new blood cells throughout the body. (wikipedia.org)
  • donors
  • At the time, there were only 3,000 bone marrow donors registered in Germany. (forbes.com)
  • Bone marrow donors have to be in good physical health and be between 18 and 55 years old. (forbes.com)
  • To facilitate the exchange of information and improve business relations, the WMDA provides access to contact data of organisations that are listing donors or cord blood products in the global database of Bone Marrow Donors Worldwide. (wikipedia.org)
  • produces
  • The marrow produces RBCs at a rate that replaces old RBCs that age and degrade or are lost through bleeding, striving to maintain a relatively constant number of RBCs in the blood. (labtestsonline.org)
  • needle
  • An aspirate needle is inserted through the skin using manual pressure and force until it abuts the bone. (wikipedia.org)
  • Then, with a twisting motion of clinician's hand and wrist, the needle is advanced through the bony cortex (the hard outer layer of the bone) and into the marrow cavity. (wikipedia.org)
  • Once the needle is in the marrow cavity, a syringe is attached and used to aspirate ("suck out") liquid bone marrow. (wikipedia.org)
  • The needle is then advanced with a twisting motion and rotated to obtain a solid piece of bone marrow. (wikipedia.org)
  • A needle is used to withdraw samples of the marrow from within the bone. (news-medical.net)
  • After the area is numb, the doctor will insert a needle and draw out the bone marrow. (upmc.com)
  • aspirate
  • The aspirate yields semi-liquid bone marrow, which can be examined by a pathologist under a light microscope and analyzed by flow cytometry, chromosome analysis, or polymerase chain reaction (PCR). (wikipedia.org)
  • drugs
  • The sensitivity of marrow to damage by radiation therapy and some anticancer drugs accounts for the tendency of these treatments to impair immunity and blood production. (britannica.com)
  • Nonsteroidal anti-inflammatory drugs (NSAIDs), in some rare instances, may also cause bone marrow suppression. (wikipedia.org)
  • vivo
  • To figure out if IL-6 is a element implicated in the ex vivo bone marrow amplification noticed in the existence of PTH and Flt-3L, bone marrow cells had been cultured for 8 times with a single remedy of PTH, Flt-3L or PTH plus Flt-3L in the existence and absence of IL-6 at the time of plating. (c14-demethylase.com)
  • diagnosis
  • Calcium elevation, renal injury, anemia, and bone lesions (CRAB features) are needed for establishing the diagnosis of active myeloma. (kjco.org)
  • Analysis
  • The aspirate yields semi-liquid bone marrow, which can be examined by a pathologist under a light microscope and analyzed by flow cytometry, chromosome analysis, or polymerase chain reaction (PCR). (wikipedia.org)
  • peripheral
  • During this rotation the student will develop the skills needed to interpret and formulate a differential diagnosis of the more commonly occurring disorders seen in peripheral blood, bone marrow, and lymph node biopsies. (bu.edu)
  • Over time, this excessive storage of fats can cause permanent cellular and tissue damage, particularly in the brain, peripheral nervous system, liver, spleen and bone marrow. (wikipedia.org)
  • precursors
  • Severe combined immunodeficiency (SCID) mice models demonstrate that these precursors may be transmitted to recipients with bone marrow allotransplants, in which case both donors' and recipients' FDCs networks may later be found in recipients' lymphoid compartments. (wikipedia.org)
  • FDCs
  • Neuroinvasion velocity correlated exclusively with the relative locations of FDCs and nerves: transfer of CXCR5-/- bone marrow to wild-type mice induced perineural FDCs and enhanced neuroinvasion, whereas reciprocal transfer to CXCR5-/- mice abolished them and restored normal efficiency of neuroinvasion. (uzh.ch)
  • Search
  • But when Shin-bi is diagnosed with leukemia and Seung-wan and Se-jin desperately search for a viable bone marrow donor, they realize how much they love each other and the family they've created. (wikipedia.org)
  • body
  • Unfortunately, Priyanka never had the chance to see that promise fulfilled: her body succumbed during a bone marrow transplant, back in Minnesota, in August 2003. (thepriyankafoundation.org)
  • The researchers, from the Liggins Institute at the University of Auckland, found that bone retains a 'memory' of exercise's effects long after the exercise is ceased, and this bone memory continues to change the way the body metabolises a high-fat diet, and published these results in Frontiers in Physiology. (membs.org)
  • Load-bearing from exercise and higher bodyweight is good for growing bones, but this and other evidence shows that if the extra weight comes from higher body fat mass, bone development may be subnormal,' he says. (membs.org)
  • Bone metabolism strongly influences energy metabolism in the body, and metabolism -- what you do with energy from diet -- is the central crux of why some children and adults become obese. (membs.org)
  • found
  • Researchers from the Liggins Institute at the University of Auckland have found that bone retains a 'memory' of exercise's effects long after the exercise is ceased, and this bone memory continues to change the way bodies metabolise a high-fat diet. (membs.org)