• Various inhibitors including ouabain (a Na+/K(+)-ATPase inhibitor), amiloride (a Na+ transport blocker), N-phenylanthranilic acid (a chloride transport inhibitor), bumetanide (an inhibitor of Na(+)-(K+)-Cl- cotransport process), and BaCl2 (a K+ channel blocker) were used on the mucosal and serosal sides of the tissue mounted in Ussing chambers to determine the involvement of the respective ion transport processes in the observed short-circuit current across the conjunctiva. (nih.gov)
  • We show that mechanical tension modulates active transport processes in neurons and that external forces can couple to internal (subcellular) forces and change the overall transport dynamics. (nature.com)
  • More physicists should be encouraged to become active in research and development in the growing application fields of biophysics including molecular genetics, biomedical imaging, tissue generation and regeneration, drug development, prosthetics, neural and brain function, kinetics of nonequilibrium open biological systems, metabolic networks, biological transport processes, large-scale biochemical networks and stochastic processes in biochemical systems to name a few. (aps.org)
  • Chemical Biotechnology involves the use of the tools and techniques of chemistry to understand and manipulate biological processes. (brocku.ca)
  • They function as a skeleton to give cells their shape and enable many biological processes such as cell to cell communication and protein transport within cells. (databasefootball.com)
  • Microtubules also enable many biological processes, such as protein transport within cells and cell to cell communication. (databasefootball.com)
  • Based on this research, you might understand how important microtubules are for normal biological processes. (databasefootball.com)
  • However, the eddies role in the biological and biogeochemical processes remain enigmatic, partially because of the challenges of in situ eddy measurements due to the spontaneity in eddy generation and present technological limitations [ 21 ]. (hindawi.com)
  • It is a promising approach for understanding the oceanic biological and physical processes and for monitoring ocean waters [ 22 - 24 ]. (hindawi.com)
  • It's a necessary component in hundreds of metabolic processes, serving as a cofactor for more than 600 biological reactions. (purebulk.com)
  • Metals are required in many different biological systems and processes, and also find application in a whole host of drugs and medical diagnostic agents. (exeter.ac.uk)
  • You will learn how organisms use metals in key life processes, such as respiration and electron transfer, how they transport and store metals and understand how we can use our knowledge of bonding and reactivity to design therapeutic and diagnostic agents at the cutting edge of medicine. (exeter.ac.uk)
  • Transition metals in biological processes, their role in electron transfer reactions, active site structures and catalytic mechanisms. (exeter.ac.uk)
  • Environmental Science: Processes & Impacts strongly prefers significant contributions whose results can be generalised to other systems, especially studies that characterise chemical processes (e.g. chemical and (micro)biological transformations and transport) as well as those that address contaminant impacts on ecosystems and human health. (rsc.org)
  • Due to its insolubility in water and octanol active or passive transport through biological membranes is unlikely. (europa.eu)
  • As this effect was observed only after bypassing the biological membranes, it supports the hypothesis that the substance is not taken up after ingestion. (europa.eu)
  • It is a complex regulatory and transport system involving many proteins and protein complexes. (wikipedia.org)
  • Effective intracellular transport of proteins and organelles is critical in cells and is especially important for ensuring proper neuron functionality. (nature.com)
  • In neurons, most proteins are synthesized in the cell body and must be transported through thin structures over long distances where normal diffusion is insufficient. (nature.com)
  • For instance, preassembled units of synaptic proteins are transported in vesicles to synapses to provide building blocks for the active zone, which is necessary for rapid fusion of synaptic vesicles 7 . (nature.com)
  • Tunnels and channels facilitate the transport of small molecules, ions and water solvent in a large variety of proteins. (plos.org)
  • Characteristics of individual transport pathways, including their geometry, physico-chemical properties and dynamics are instrumental for understanding of structure-function relationships of these proteins, for the design of new inhibitors and construction of improved biocatalysts. (plos.org)
  • Transport pathways play an essential role in the functioning of a large number of proteins. (plos.org)
  • Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. (nih.gov)
  • Active commuting by bicycle is associated with a substantial decrease in the risk of death from all causes, cancer and cardiovascular disease (CVD), compared with non-active commuting by car or public transport, according to a study published in April 2017 The BMJ . (thirdage.com)
  • 2018 ) Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulence. (academictree.org)
  • Besides many tiny cavities, this empty internal spa`ce may form cavities of specific functions, as well as tunnels and channels (or pores), representing potential transport pathways for small molecules, ions and water molecules [1] . (plos.org)
  • In this research, the team developed a new SERS method for active capture of target molecules in small gaps between multiple layers that were naturally smaller than 3 nm, which was based on their previous research on the SERS method for automatic capture of target molecules in single-layer nanofilm hotspots. (news-medical.net)
  • The results opened up new methods for the active transport of target molecules to optimal hotspots and were expected to enable ultra-sensitive detection or monitoring of biological systems in the direction of material transformation, cell behavior or chemical kinetic process studies. (news-medical.net)
  • This makes transporting vaccines around the world a complex undertaking and is why many rural areas around the world have very poor access to vaccinations. (springwise.com)
  • Now, however, researchers may have found a way to transport vaccines safely at higher temperatures. (springwise.com)
  • Our goal is to make the transportation of vaccines and other life-saving biological materials more efficient and cost-effective, while also reducing the carbon footprint of this critical supply chain. (springwise.com)
  • Springwise has spotted other ideas aiming to protect the efficacy of vaccines, including transporting them as a microneedle patch , and using sugar to protect vaccines from heat. (springwise.com)
  • At approximately 8:20 a.m. Tuesday, April 6, 2021, the Frederick Police Department responded to the 8400 Block of Progress Drive for reports of an active shooter. (cityoffrederick.com)
  • As an example, if a synaptic protein is synthesized in the cell body, it may need to be transported the entire length of the axon (which could be over 1 meter in a human) to reach its functional target. (nature.com)
  • however, there is no evidence that the protein persists in the environment nor that it is active in humans. (cdc.gov)
  • Fluoride exposure also significantly elevated the protein expressions of cytochrome c and active caspase-3. (fluoridealert.org)
  • Neurons transport subcellular cargo along axons and neurites through a stochastic interplay of active and passive transport. (nature.com)
  • To this end, we investigate the active and passive transport of vesicles in Aplysia neurons while changing neurite tension via applied strain and quantify the resulting dynamics. (nature.com)
  • Cargo transport in cells is mediated by a stochastic interplay of passive diffusion and active transport 2 . (nature.com)
  • Fig. 1a,b shows a representative image and a schematic of a vesicle switching between active transport along a microtubule and passive diffusion in the subcellular space. (nature.com)
  • Vesicles switch stochastically between active and passive transport states. (nature.com)
  • Vesicles alternate between active transport along microtubules and passive brownian-like motion. (nature.com)
  • This example clearly shows the vesicle switching between active and passive behavior. (nature.com)
  • The inset shows the slope of the average MSD for active (green) and passive (red) vesicle motion for the trajectory shown. (nature.com)
  • d,e) Plots of the x and y position as a function of time show that particle behavior is passive (red) most of the time and that when vesicles undergo active motion (green) they are moving over larger distances. (nature.com)
  • Our warehousing facilities are Healthcare QMS and GDP-certified and we can transport your sensitive products all over the world using both active containers and passive packaging. (dsv.com)
  • This passive flux exceeded active POC flux by ~10-fold. (int-res.com)
  • A. Passive Transport. (mcqser.com)
  • This chapter presents the development of the latest version of HYDROGEOCHEM a multidimensional numerical model of coupled fluid flow, thermal transport, hydrologic transport, and biogeochemical kinetic/equilibrium reactions in saturated/unsaturated media. (benthamscience.com)
  • It iteratively solves the Richards equation for fluid flow, the thermal transport equation for temperature fields, and reactive biogeochemical transport equations for concentration distributions. (benthamscience.com)
  • Chapter 2 describes modified ZnO nanoparticles as electron transport layer to improve the performance and stability of organic solar cells. (umass.edu)
  • Electron transport and cytochromes. (exeter.ac.uk)
  • To provide grounding in the basic principles of Biochemistry for students in Biological Sciences. (manchester.ac.uk)
  • Successful completion of an Honours Bachelor's degree, or equivalent, normally with an average of not less than 78%, or the equivalent grade point average in major courses in an undergraduate program in biotechnology, chemistry, or the biological sciences (composed of but not limited to biochemistry, biology, genetics, or microbiology). (brocku.ca)
  • Students with undergraduate degrees in chemistry or the biological sciences will be exposed to the breadth of biotechnology through mandatory participation in the seminar program and will have the opportunity to focus on selected areas of biotechnology in other graduate courses. (brocku.ca)
  • Normally, only one of these three additional half-credit courses may be taken from among 5(alpha)00 or 4(alpha)00 level courses offered by the Departments of Biological Sciences, Chemistry or Physics, which are not cross-listed with the Biotechnology program. (brocku.ca)
  • Successful completion of an appropriate Master's degree in Biotechnology, Biophysics, Chemistry or the Biological Sciences (composed of but not limited to Biochemistry, Biology, Genetics or Microbiology). (brocku.ca)
  • Plants use intricate systems for growth, development, transport and metabolism to cope with adverse environmental conditions, but also have considerable capacity to adapt genetically to both biotic and abiotic factors. (lu.se)
  • The part of the enzyme where the substrate binds is called the active site . (khanacademy.org)
  • A substrate entering the active site of the enzyme. (khanacademy.org)
  • Investigating the mechanisms of neuronal transport is critical in understanding neuronal function. (nature.com)
  • An understanding of the mechanisms that underlie these features is of fundamental importance for all biological disciplines. (lu.se)
  • Mechanical tension is critical in maintaining proper function in neurons, but its role in transport is not well understood. (nature.com)
  • We found that tension in neurons modulates active transport of vesicles by increasing the probability of active motion, effective diffusivity and induces a retrograde bias. (nature.com)
  • CAVER 3.0 paves the way for the study of important biochemical phenomena in the area of molecular transport, molecular recognition and enzymatic catalysis. (plos.org)
  • Gene biotechnology involves the use of DNA technology, bioinformatics and microbiological techniques to study biological phenomena. (brocku.ca)
  • Another area of research is transport phenomena in manufacturing and materials processing, which includes investigations of rapid solidification of molten metals and shape-controlled deposition of organic materials. (ucsb.edu)
  • Oxazolidinone antibiotics are active against many Gram-positive bacteria, but are only weakly active against Gram-negative pathogens. (rsc.org)
  • ATP can only become biologically active by binding to a magnesium ion. (purebulk.com)
  • Before the 20th century, biological warfare took three main forms: (1) deliberate poisoning of food and water with infectious or toxic material, (2) use of microorganisms or toxins in some form of weapon system, and (3) use of biologically inoculated fabrics. (medscape.com)
  • Active behavior resembles directed motion where the mean squared displacement is proportional to the square of time (MSD ∝ V 2 τ 2 ). (nature.com)
  • 2018 ) Exploiting the vulnerable active site of a copper-only superoxide dismutase to disrupt fungal pathogenesis. (academictree.org)
  • and (3) Exploiting standing acoustic waves to transport rigid particles. (cam.ac.uk)
  • nanoparticles in biological tissue for medical appplications, and more. (dissertation.com)
  • We find that despite its broad metal-recognition profile, MntBC-A imports only manganese, whereas zinc can function as a high-affinity inhibitor of MntBC-A. Computational analysis shows that the transmembrane metal permeation pathway is lined with six titratable residues that can coordinate the positively charged metal, and mutagenesis studies show that they are essential for manganese transport. (nih.gov)
  • Eddies are crucial to the transport of heat, momentum, trace chemicals, biological communities, the oxygen, and nutrients relating to life in the sea [ 2 ]. (hindawi.com)
  • Oxygen transport and storage. (exeter.ac.uk)
  • This is particularly inopportune at a time when the needs for quantitative thinking about biological systems are exploding. (aps.org)
  • These types of systems are present in many active areas of research in the nanotechnology sphere. (dissertation.com)
  • In this thesis I outline an approach to solving light transport in nanomaterial systems based on the Monte-Carlo method. (dissertation.com)
  • Bioinorganic Chemistry - Topics covered will include: Metal management in biological systems. (exeter.ac.uk)
  • The potential spectrum of bioterrorism ranges from hoaxes and actual use of agents by individuals or groups against others, to state-sponsored terrorism that employs biological warfare (BW) agents and delivery systems that can produce mass casualties. (medscape.com)
  • The properties of water in biological systems have been studied for well over a century by a wide range of physical techniques, but progress has been slow and erratic. (lu.se)
  • The properties of water in biological systems have been are discussed, we emphasize magnetic-relaxation tech- studied for well over a century by a wide range of physical niques and, in particular, MRD. (lu.se)
  • Active transport is directed motion along cytoskeletal structures that is driven by molecular motors 4 . (nature.com)
  • CAVER is a software tool widely used for the identification and characterization of transport pathways in static macromolecular structures. (plos.org)
  • Studies on implementation of drag-reducing fluids in industrial applications such as HVAC or fluid transport are conducted through laboratory and large-scale field tests. (ucsb.edu)
  • The German-American physician Anton Dilger established a secret biological laboratory in Chevy Chase, Maryland, with the intent to grow the causative agents of anthrax and glanders. (medscape.com)
  • Additionally, the semitransparency of biological tissue between 700 and 1000 nm makes such light sources appealing for a broad class of biomedical applications, particularly imaging and sensing. (europa.eu)
  • Fulvic Acid can now freely, without restriction of these unwanted salt acids, transport nutrients into our cells , as it was made to do. (optimallyorganic.com)
  • All the gene involved in the transport of maltose/maltodextrin, including malE, are clustered in the malB region of E. coli and organized in two divergent operons: malE-malF-malG and malK-lamB. (wikipedia.org)
  • Study Biological Method lecture notes PDF with college biology definitions and explanation to study "What is Biological Method? (techleens.com)
  • Study biological method definitions with college biology terms to review biology course for online degree programs. (techleens.com)
  • Only transport insufficient physical activity (OR=2.24, 95% CI=1.01-4.98) and being in the age group from 30 to 59 years (OR=8.79, 95% CI=3.41-22.64) maintained statistical significance. (bvsalud.org)
  • When the vaccine is ready to be administered, the silica cage cracks open and falls away, leaving the active ingredient in its pure and fully functional form. (springwise.com)
  • Whichever method or methods of transport you choose for your products, you can be sure that they are handled in full compliance with regulations and the required temperature - even during breaks in the journey. (dsv.com)
  • If you need to transport your goods by sea while maintaining the exact temperature conditions your products require, we can offer cold chain transport that reduces both cost and carbon footprint. (dsv.com)
  • Finally, road transport with temperature-controlled trucks can be used for the first or final leg of the journey to ensure the cold chain is maintained from pick-up to delivery. (dsv.com)
  • The technology uses inert silica to encapsulate the active ingredients with a protective 'cage', which keeps the biological material protected from any variations in outside temperature or humidity. (springwise.com)
  • I mplementing TDG accident prevention, preparedness and response measures focusing on transport companies, first responders and security services based on best available practices and harmonised across the Sahel region. (fiiapp.org)
  • Microtubule filaments composed of tubulins are now known to play an active role in chromosome separation. (databasefootball.com)
  • Magnesium supports muscle, immune, and nerve function and plays a distinctive role in energy transport. (purebulk.com)
  • The added value of this European Union Initiative is to promote a holistic view of the risks and threats of Chemical, Biological, Radiological and Nuclear Risks that are sufficiently addressed separately despite numerous commonalities and to make available to participants an international resource of authorities and experts who meet regularly. (fiiapp.org)
  • Biological methods helps in studying living things including experiments and different approaches and tools for biological research. (techleens.com)
  • In this work, we describe a number of efficient and locally conservative methods for subsurface flow and reactive transport that have been or are currently being implemented in the IPARS (Integrated Parallel and Accurate Reservoir Simulator). (benthamscience.com)
  • This review evaluates the potential for environmental transport and bioavailability of the active chemical to humans. (cdc.gov)
  • In addition, the activities addressed the transport of biological samples and included specific training on how to respond to accidents involving hazardous biological and chemical materials . (fiiapp.org)
  • In 2010, the European Union launched the Chemical, Biological, Radiological and Nuclear (CBRN) Risk Mitigation Centres of Excellence . (fiiapp.org)
  • E stablishing a comprehensive legal framework tailored to each country, including local training for security advisors, carriers and drivers, with a focus on chemical and biological materials. (fiiapp.org)
  • This was the first multilateral agreement that extended prohibition of chemical agents to biological agents. (medscape.com)
  • Council Directive 80/1107/EEC, as amended by Council Directive 88/642/EEC, on the protection of workers from the risks related to exposure to chemical, physical and biological agents at work, introduced into EU legislation the objective of establishing occupational exposure limits (OELs) agreed by Member States. (cdc.gov)
  • For the optimisation of bulk heterojunction (BHJ) solar cells FAU investigated the concept of ternary and quaternary polymer/fullerene blends for the active layer of bulk heterojunction solar cells. (europa.eu)
  • On the more fundamental side, we are investigating non-Newtonian fluid mechanics and heat transfer, with experimental investigations of the characteristics of complex fluids such as surfactant solutions or polymer solutions, especially turbulent flow of drag-reducing fluids and issues of active control of convective heat transfer. (ucsb.edu)
  • So researchers at the University of Glasgow set out to investigate the association between active commuting and incident CVD, cancer, and all cause mortality. (thirdage.com)
  • The teachers are active researchers and you will gain insight in plant research on the molecular, cell, physiological and ecological level. (lu.se)
  • Today, there is a growing demand for quantitative and computational skills in biological research and the commercialization of that research. (aps.org)
  • According to scientific research the biological method has participated to the advancement in medicine, ecology, technology etc. (techleens.com)
  • There are various steps involved in conducting biological analysis like, developing research question, observation, forming hypotheses, recording data and conclusion. (techleens.com)
  • The location of the initial shooting is a warehouse rented by Naval Medical Research Center, Biological Defense Research Directorate to store research supplies and equipment. (cityoffrederick.com)
  • During World War II, the Japanese operated a secret biological warfare research facility in Manchuria and carried out human experiments on Chinese prisoners. (medscape.com)
  • Subsequent analysis show that EVs transfer their functionally active receptors to target cells, making them prone to an otherwise unresponsive state. (lu.se)
  • We measured the gut passage time (GPT) of common migrant species at the Bermuda Atlantic Time-series Study (BATS) site, using the gut fluorescence method, to determine whether GPT is slow enough to allow active export of POC and PON to depth. (int-res.com)
  • Biological method also ensures the quality of data for public use. (techleens.com)
  • Once Optimally Organic Fulvic Ionic Minerals X200™ comes into contact with a cell, they both balance and energize that cell's life and biological properties . (optimallyorganic.com)
  • Infiltration versus metastasis is one of the most characteristic biological properties of tumors [ 5 ]. (hindawi.com)
  • Inspired by the biological world, the engineering community been very active in designing and implementing synthetic swimming strategies. (cam.ac.uk)
  • During World War I, the Germans developed anthrax, glanders, cholera, and a wheat fungus for use as biological weapons. (medscape.com)
  • The following is a joint statement between Frederick Police Department, Fort Detrick and the Federal Bureau of Investigations Baltimore Field Office regarding an active shooter incident that occurred in Frederick Tuesday. (cityoffrederick.com)
  • Scientific method in which biological problems are solved is termed as biological method. (techleens.com)
  • With our own warehouses and air charter network , as well as an extensive network of ocean and road transport providers , we are able to have full control of cold chain logistics - from origin to destination. (dsv.com)
  • Serious' effects are those that evoke failure in a biological system and can lead to morbidity or mortality (e.g., acute respiratory distress or death). (cdc.gov)