• vancomycin
  • Examples include: Amanitins Bacitracin Colistin Ciclosporin Dactinomycin Daptomycin Gramicidin S Hymenistatin Microcystins Nisin Nodularin Octreotide Polymyxin B Pristinamycin Valinomycin (technically a depsipeptide) Vancomycin Viscumamide Yunnanin A Nonribosomal peptide lantibiotics, 19-37 residues and 1 to 5 'bridges' Jensen, Knud (2009-09-01). (wikipedia.org)
  • interferes
  • Staphylococcus aureus - ≤0.03 μg/mL - 700 μg/mL Staphylococcus epidermidis - 0.25 μg/mL - >16 μg/mL Streptococcus pyogenes - 0.5 μg/mL - >16 μg/mL Bacitracin interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, also known as bactoprenol, a membrane carrier molecule that transports the building-blocks of the peptidoglycan bacterial cell wall outside of the inner membrane. (wikipedia.org)
  • Bacillus
  • Bacitracin is a widely used metallopeptide antibiotic produced by Bacillus subtilis and B. licheniformis with a potent bactericidal activity directed primarily against Gram-positive organisms. (usf.edu)
  • Bacitracin is a mixture of related cyclic peptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, first isolated in 1945. (wikipedia.org)
  • cyclic
  • Cyclic isopeptides contain at least one non-alpha amide linkage, such as a linkage between the side chain of one residue to the alpha carboxyl group of another residue, as in microcystin and bacitracin. (wikipedia.org)
  • membrane
  • In this review, the results from physical (including NMR, EPR, and EXAFS) and molecular biological studies regarding the synthesis and structure of bacitracin, the coordination chemistry of its metal derivatives, the mechanism of its antibiotic actions, its influence on membrane function, and its structure and function relationship are discussed. (usf.edu)