• Other strains of Bacillus bacteria that phage are known to infect include B. megaterium, B. mycoides, B. pseudomycoides, B. thuringiensis, and B. weihenstephanensis. (wikipedia.org)
  • By supplying a refuge to phage-sensitive strains, we show that seed banks retained phenotypic diversity that was otherwise lost to selection. (nature.com)
  • Virulent phage, lyses 85% of all Listeria strains. (ulaval.ca)
  • We isolated and are now investigating phages which kill Bacillus strains. (wroc.pl)
  • Such changes in the lipid profile of B. subtilis reduce membrane fluidity thereby conferring resistance against detergents and antimicrobial compounds produced by competing Bacillus strains. (cornell.edu)
  • Diphtheria is an acute pharyngeal or cutaneous infection caused mainly by toxigenic strains of the gram-positive bacillus Corynebacterium diphtheriae and rarely by other, less common Corynebacterium species. (msdmanuals.com)
  • Diphtheria strains infected by a beta-phage, which carries a toxin-encoding gene, produce a potent toxin. (msdmanuals.com)
  • Metagenome-derived genome sequence analysis revealed the dominance of phages of Streptococcus, Bacillus and Escherichia, with nearly 50% abundance of streptococcus phage in fresh urine. (bvsalud.org)
  • The experimental part focus on the model organisms, Bacillus subtilis , Escherichia coli and Streptomyces coelicolor . (lu.se)
  • A Bacillus phage is a member of a group of bacteriophages known to have bacteria in the genus Bacillus as host species. (wikipedia.org)
  • The role of phage tRNAs largely depend on their bacterial host, hence the number could widely differ depending on the specific strain of bacteria. (wikipedia.org)
  • Owing in part to the inability of phages to attach to spores, seed banks stabilized population dynamics and resulted in minimum host densities that were 30-fold higher compared to bacteria that were unable to engage in dormancy. (nature.com)
  • Based on mutational trajectories over the course of the experiment, we demonstrate that seed banks can dampen bacteria-phage coevolution. (nature.com)
  • By Arianna Chase, Jay Boudreau Faculty mentor: Dr. Swati Agrawal Bacillus anthracis, the bacteria responsible for the serious infectious disease anthrax, can easily become antibiotic resistant. (umwrcd.net)
  • The bacteria designated by the acronym SERMOR-PROVENF (SER = Serratia, MOR = Morganella, PROV = Providencia, EN = Enterobacter, F = freundii for Citrobacter freundii ) have similar, although not identical, chromosomal beta-lactamase genes that are inducible. (medscape.com)
  • The genus Bacillus includes the model organism, B. subtilis, and two widely known human pathogens, B. anthracis and B. cereus. (wikipedia.org)
  • Emma Piligrimova and colleagues at the Skryabin Institute of Biochemistry and Physiology of Microorganisms in Russia published a paper on a new Bacillus phage that was previously thought to be a plasmid , and which also appears to represent a new Siphoviridae genus. (phage.directory)
  • Bacteriophages or phages are bacterial viruses. (wroc.pl)
  • Using E.coli T1 bacteriophage, the reduction in phage could be measured and the reduction equivalent fluence (REF) calculated. (fwr.org)
  • Isolation and characterization of Bacillus cereus bacteriophage DZ1 and its application in foods. (cabi.org)
  • The most conserved genes within the Bacillus phage include those that encode tail proteins and other structural proteins, holin, and a site-specific recombinase. (wikipedia.org)
  • One group of gene that is highly variable between Bacillus phage are tRNA genes. (wikipedia.org)
  • After characterizing allelic variation with pooled population sequencing, we found that seed banks retained twice as many host genes with mutations, whether phages were present or not. (nature.com)
  • These loci include genes encoding phage shock proteins, tellurite resistance related proteins, signal peptide peptidase, and proteins that synthesize and modify teichoic acids. (cornell.edu)
  • Here we describe an African swine fever virus (ASFV) protein encoded by the open reading frame 5-AR that shares structural and functional similarities with the family of bacterial histone-like proteins which include histone-like DNA binding proteins, integration host factor, and Bacillus phage SPO1 transcription factor, TF1. (illinois.edu)
  • Binding of phage Phi29 architectural protein p6 to the viral genome: evidence for topological restriction of the phage linear DNA. (neb.com)
  • Sequence requirements for protein-primed initiation and elongation of phage O29 DNA replication. (neb.com)
  • Oligomeric structures of the phage phi29 histone-like protein p6. (neb.com)
  • Phage phi29 protein p6 is in a monomer-dimer equilibrium that shifts to higher association states at the millimolar concentrations found in vivo. (neb.com)
  • Functional domain for priming activity in the phage phi 29 terminal protein. (neb.com)
  • Signals in the phi 29 DNA-terminal protein template for the initiation of phage phi 29 DNA replication. (neb.com)
  • Location of the serine residue involved in the linkage between the terminal protein and the DNA of phage phi 29. (neb.com)
  • Purification in a functional form of the terminal protein of Bacillus subtilis phage phi 29. (neb.com)
  • METHODS: Rhesus macaques exposed to an aerosol of Bacillus anthracis spores were treated with ciprofloxacin, clindamycin, or ciprofloxacin + clindamycin after becoming bacteremic. (cdc.gov)
  • Isolates of Salmonella were further characterized by phage typing and ribotyping. (who.int)
  • Bacillus phage are classified based on their genome sequences. (wikipedia.org)
  • Complete Genome Sequences of Bacillus Phages Janet and OTooleKemple52. (virginia.edu)
  • Activation of replication origins in phi29-related phages requires the recognition of initiation proteins to specific nucleoprotein complexes. (neb.com)
  • We conducted a factorially designed experiment where we passaged a bacterial host ( Bacillus subtilis ) and its phage (SPO1) in the presence versus absence of a seed bank consisting of dormant endospores. (nature.com)
  • Emerging strategies to combat and treat ESKAPE pathogens including Enterobacter include consideration for combination antibiotics, phage therapy, antimicrobial peptides, silver nanoparticles and photodynamic light therapy. (medscape.com)
  • In previous studies, we suggested that this inhibition is likely a defense mechanism developed by phage phi29 to prevent the action of UDG if uracilation occurs in DNA either from deamination of cytosine or the incorporation of dUMP during viral DNA replication. (nih.gov)
  • The detailed knowledge of in vitro phage Φ29 DNA replication and transcription regulation makes it an attractive model to study these processes in vivo . (bionity.com)
  • For many years it has been known that (i) phage Φ29 DNA replication, as well as that of other prokaryotic genomes, occurs at the cytosolic membrane, and (ii) the lytic Φ29 cycle is suppressed in early sporulating cells and under these conditions the infecting phage genome becomes trapped into the spore. (bionity.com)
  • The most distantly related phage of this family, GA-1, is unable to infect the standard B. subtilis strain 168 and has been placed in a third group. (bionity.com)
  • This paper closely investigates Cluster K phages, including looking at immunity and introducing the discovery of Start-Associated-Sequences (SAS) and Extended Start Associated Sequences (ESAS). (phagesdb.org)
  • With 192 authors contributing to the discovery and characterization of 18 new phages, this paper brought the total number of published mycobacteriophage genomes to 80. (phagesdb.org)
  • Only 164 of these phages have been completely sequenced as of December 16, 2021. (wikipedia.org)
  • CusabioAlternative Name(s): /Gene Names: ddaResearch Areas: NeuroscienceOrganism: Enterobacteria phage. (joplink.net)
  • CusabioAlternative Name(s): Gene Names: uvsYResearch Areas: OthersOrganism: Enterobacteria phage T4. (joplink.net)
  • This should demostrate that the S. thermophilus CRISPR1/Cas system can be transferred into Bacillus subtilis and provide heterologous protection against plasmid transformation and phage infection. (igem.org)
  • Also in this issue: BiomX entering the stock market, Pherecydes partnering with a not-for-profit to make phages for UTIs, Bayer launching a phage crop disease company, plenty of new job openings at Eligo, grant funds for studying human-microbe interactions, a Bacillus phage mistaken for a plasmid, and a mini phage bioinformatics Q&A for beginners. (phage.directory)
  • It is an ideal host system for the isolation of B. subtilis phages and their genetic engineering. (phage.one)
  • This week, Sabrina Green, a graduate student at Baylor College of Medicine, tells us how gut pathogens like ExPEC could be treated with phages, describes the challenges, and highlights her own research on the topic. (phage.directory)
  • Perhaps phage researchers studying phage interactions with the microbiome/pathogens/human host could fit their research into this scope? (phage.directory)
  • BiomX, a biotech company developing natural and engineered phages to treat microbiome diseases, announced a merger agreement with Chardan Healthcare Acquisition Corp . The combined company is expected to be listed on the New York Stock Exchange under the name BiomX, and will proceed with developing BiomX's phage products. (phage.directory)
  • We are looking for passionate and driven scientists with expertise in synthetic biology to join our international and highly motivated team in Paris working on next-generation tools for editing the microbiome (engineered phages, CRISPR systems, etc. (phage.directory)
  • For our project we have PCR amplified the CRISPR1 locus from the chromosome of Streptococcus thermophilus [LMD-9] and ligated it into an integration vector to place it on the chromosome of Bacillus subtilis through allelic recombination on the chromosome. (igem.org)
  • Not related to other Listeria phages. (ulaval.ca)
  • [1] These phages, which form part of the Podoviridae family , are the smallest Bacillus phages isolated to date and are among the smallest known dsDNA phages. (bionity.com)
  • The ideal candidate has experience in microbiology, phage biology and molecular biology. (phage.directory)
  • Bacillus cereus is a pathogenic bacterium that causes food contamination, resulting in food poisoning such as diarrhea and emesis. (cabi.org)
  • The paper discusses (among other topics) overall phage diversity, mobile elements, and immunity/immunity theft. (phagesdb.org)
  • Phage Φ29 has also been proven to be a versatile system to study in vitro transcription regulation in general and the switch from early to late phage transcription in particular. (bionity.com)
  • Schilling T, Dietrich S, Hoppert M, Hertel R (2018) A CRISPR-Cas9-based toolkit for fast and precise in vivo genetic engineering of Bacillus subtilis phages. (phage.one)