• Editor-In-Ch
  • The editor in chief of Autoimmunity is Paolo Casali, the Donald L Bren Professor of Medicine, Molecular Biology & Biochemistry and Director of the Institute for Immunology at the University of California at Irvine. (wikipedia.org)
  • Protective
  • Protective autoimmunity is a condition in which cells of the adaptive immune system contribute to maintenance of the functional integrity of a tissue, or facilitate its repair following an insult. (wikipedia.org)
  • The term 'protective autoimmunity' was coined by Prof. Michal Schwartz of the Weizmann Institute of Science (Israel), whose pioneering studies were the first to demonstrate that autoimmune T lymphocytes can have a beneficial role in repair, following an injury to the central nervous system (CNS). (wikipedia.org)
  • Most of the studies on the phenomenon of protective autoimmunity were conducted in experimental settings of various CNS pathologies and thus reside within the scientific discipline of neuroimmunology. (wikipedia.org)
  • Additional work by the Schwartz group has shown that protective autoimmunity is a naturally occurring physiological phenomenon that takes place spontaneously following a CNS injury. (wikipedia.org)
  • experimental
  • In recent years, several studies both in clinical settings and experimental models proposed that the epigenome may hold the key to a better understanding of autoimmunity initiation and perpetuation. (nih.gov)
  • regulation
  • QIAGEN provides a broad range of assay technologies for inflammatory response and autoimmunity research that enables analysis of gene expression and regulation, epigenetic modification, genotyping, and signal transduction pathway activation. (qiagen.com)
  • human
  • The Human Inflammatory Response & Autoimmunity miScript miRNA PCR Array profiles the expression of 84 miRNAs predicted to regulate the expression of proinflammatory or antiinflammatory genes. (qiagen.com)
  • further
  • Taking the experience of a beneficial factor in autoimmunity further, one might hypothesize with intent to prove that autoimmunity is always a self-defense mechanism of the mammal system to survive. (wikipedia.org)