Autacoids. Medical search. Frequent questions

A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. (lookformedical.com)
The endogenous compounds that mediate inflammation (AUTACOIDS) and related exogenous compounds including the synthetic prostaglandins (PROSTAGLANDINS, SYNTHETIC). (reference.md)
A simplification of this process is as follows: Cell injury results in the release of prostaglandins, leukotrienes, bradykinin, substance P, and other autacoids. (nationalacademies.org)

Each class of enzymatically produced eicosanoids governs a specific set of functions and is thought to serve as a mediator or autacoid, acting within a local microenvironment to orchestrate key cellular responses. (jci.org)

NAM enhances NAD via the enzyme NAMPT and augments production of the fat breakdown product β-hydroxybutyrate, leading to increased production of prostaglandin PGE2 (ref. 5), a secreted autacoid that maintains renal function. (nih.gov)
1. The response of the isolated rat kidney to a mixed amino acid solution was examined in the presence of three renal autacoid inhibitors, indomethacin (a cyclo-oxygenase inhibitor), sulpiride (a dopamine antagonist) and l -nitroarginine methyl ester (an inhibitor of nitric oxide synthesis). (portlandpress.com)

With respect to vascular smooth muscle, there exist both vasoconstrictor and vasodilator autacoids. (wikipedia.org)

Autacoids or autocoids are biological factors (molecules) which act like local hormones, have a brief duration, and act near their site of biosynthesis. (wikipedia.org)

The effects of autacoids are primarily local, though large quantities can be produced and moved into circulation. (wikipedia.org)
citation needed] Autacoids may thus have systemic effects by being transported via the circulation. (wikipedia.org)

A paradigm shift is emerging in our understanding of the resolution of inflammation as an active biochemical process with the discovery of novel endogenous specialized pro-resolving lipid autacoid mediators (SPMs), such as resolvins. (nih.gov)

Autacoids or autocoids are biological factors (molecules) which act like local hormones, have a brief duration, and act near their site of biosynthesis. (wikipedia.org)
Abstract: Biosynthesis of all-trans-retinoic acid (RA) from retinol (vitamin A) produces an autacoid that regulates cell fate specification and functions of differentiated cells, including fuel use, immune function, and nervous system function, to name a few. (nih.gov)
This project will generate data significant to retinoid homeostasis, RA biosynthesis, and the function of LD as sources of autacoids, and will provide insight into the role of retinoid metabolism with respect to LD- associated diseases, such as cancer, inflammation, and diabetes. (nih.gov)

Therefore ACh causes electromechanical rest of soft muscle cells across the vessel initiated by regional KCa as well as the ensuing 'influx' of Ca2+ across the endothelium produces autacoids to market pharmacomechanical relaxation. (cancerrealitycheck.com)

Also, the mechanisms regulating the synthesis and activation of locally acting autacoids such as endothelins, cytokines known to have potent effects on contractile function and gene expression in cardiac myocytes, are unknown, as their cells of origin within ventricular muscle. (jci.org)

Autacoids can have a variety of different biological actions, including modulating the activities of smooth muscles, glands, nerves, platelets and other tissues. (wikipedia.org)

Hydrangea, unconquered shrouded, in order that syndrome's - physicals Achat générique prelone prelone pays bas in overkind vagi excelling "acheter avis ligne 40mg prelone en 5mg 10mg 20mg" solely nobody vouchsafing thru whichever Sulfachlorpyridazine bestellen drugs vardenafil met paypal lactovegetarianism. (blindman.be)

The effects of autacoids are primarily local, though large quantities can be produced and moved into circulation. (wikipedia.org)