• Commercially available midazolam hydrochloride injection (Versed®) and atracurium besylate injection (Tracrium,® Glaxo Wellcome) were used to prepare four different drug combinations in 5% dextrose injection. (ijpc.com)
  • tobramycin increases effects of atracurium by pharmacodynamic synergism. (medscape.com)
  • Atracurium besilate, also known as atracurium besylate, is a medication used in addition to other medications to provide skeletal muscle relaxation during surgery or mechanical ventilation. (wikipedia.org)
  • The objective of this study was to evaluate the physical stability and chemical compatibility of midazolam hydrochloride and atracurium besylate for intravenous coadministration at concentrations normally encountered in clinical practice. (ijpc.com)
  • The final concentration of midazolam (as the hydrochloride salt) and of atracurium (as the besylate salt) was 0.1 or 0.5 mg/mL and 1 or 5 mg/mL, respectively. (ijpc.com)
  • The chemical stability of midazolam and atracurium in combination was evaluated using a stability-indicating high-performance liquid chromatography assay, capable of simultaneous analysis of both compounds, developed in our laboratory. (ijpc.com)
  • Midazolam was detected using an ultraviolet detector and atracurium with a fluorescence detector. (ijpc.com)
  • Midazolam hydrochloride and atracurium besylate are physically stable and chemically compatible for up to three hours at room temperature under normal fluorescent lighting at the concentrations used in this study and may be coinfused at a ysite without loss of potency. (ijpc.com)
  • Indeed, because laudanosine is cleared primarily via renal excretion, a cat study modelling anephric patients went so far as to corroborate that EEG changes, when observed, were evident only at plasma concentrations 8 to 10 times greater than those observed in humans during infusions of atracurium. (wikipedia.org)
  • The total dose of administered atracurium was 40 mg and total duration of anesthesia was 360 minutes. (ekja.org)
  • Assess respiratory status continuously throughout therapy with atracurium. (unboundmedicine.com)
  • We anesthetized her with atracurium under the monitoring of an accelerograph and she did not represent any prolonged respiratory paralysis postoperatively. (ekja.org)
  • Risk of environmental impact of atracurium cannot be excluded, due to the lack of environmental toxicity data. (janusinfo.se)
  • Fortunately, both for the public and for atracurium, rapid initial investigations irrefutably failed to find any overt or EEG evidence for a connection between atracurium administration and epileptogenic activity. (wikipedia.org)
  • Administration of anticholinesterase agents (neostigmine, pyridostigmine) may be used to antagonize the action of atracurium once the patient has demonstrated some spontaneous recovery from neuromuscular block. (unboundmedicine.com)
  • Administration of Atracurium in a Patient Recovering from Organophosphate Poisoning. (ekja.org)
  • Atracurium has previously been found in the aquatic environment in Sweden. (janusinfo.se)
  • We did not extubate her in the operating room in spite of complete recovery from atracurium to preoperative status because her lung condition was not very good preoperatively and severe necK flexion was done for the anastomosis. (ekja.org)
  • Atracurium is in the neuromuscular-blocker family of medications and is of the non-depolarizing type. (wikipedia.org)
  • We administered atracurium 10 mg twice initially and then gave additional 5 mg boluses when the TOF ratio became greater than 0.5. (ekja.org)
  • An atracurium besylate dose of 0.4 to 0.5 mg/kg (1.7 to 2.2 times the ED95), given as an intravenous bolus injection, is the recommended initial dose for most patients. (ncats.io)
  • An initial atracurium dose of 0.4 to 0.5 mg/kg generally produces maximum neuromuscular block within 3 to 5 minutes of injection, with good or excellent intubation conditions within 2 to 2.5 minutes in most patients. (nih.gov)
  • We are China supplier for Atracurium Besylate raw material, a muscle relaxant pharmaceutical raw material acts as a non-depolarizing neuromuscular blocking agent. (inopha.net)
  • Consider using an atracurium product that has no benzyl alcohol preservative. (nih.gov)
  • Use of atracurium besylate from multiple dose vials containing benzyl alcohol as a preservative is contraindicated. (pfizermedicalinformation.com)
  • Cisatracurium in different doses versus atracurium during general anesthesia for abdominal surgery. (ncats.io)
  • To compare the hemodynamic effects of Atracurium versus Cisatracurium in Cardiac Patients Undergoing coronary artery bypass graft Surgery. (pafmj.org)
  • Group-A patients were induced with 0.5mg/kg of Atracurium, followed by infusion @ 10μg/kg/min whereas group C patients received Cisatracurium @ 0.2mg/kg at induction, followed by infusion @ 2μg/kg/min during the maintainence phase. (pafmj.org)
  • Systolic and diastolic blood pressure was better maintained with cisatracurium than atracurium. (pafmj.org)
  • The duration of neuromuscular block produced by atracurium is approximately one-third to one-half the duration of block by d-tubocurarine, metocurine, and pancuronium at initially equipotent doses. (nih.gov)
  • Drug interactions are reported among 44 people who take Atracurium besylate and Atropine. (ehealthme.com)
  • The phase IV clinical study analyzes what interactions people who take Atracurium besylate and Atropine have. (ehealthme.com)
  • 44 people who take Atracurium besylate and Atropine together, and have interactions are studied. (ehealthme.com)
  • Do you take Atracurium besylate and Atropine? (ehealthme.com)
  • It is based on atracurium besylate and atropine (the active ingredients of Atracurium besylate and Atropine, respectively), and Atracurium besylate and Atropine (the brand names). (ehealthme.com)
  • Atracurium is an intermediate-duration, nondepolarizing, skeletal muscle relaxant for intravenous administration. (ncats.io)
  • Atracurium besylate is a nondepolarizing skeletal muscle relaxant. (nih.gov)
  • 18. Inhibition of the neuromuscular acetylcholine receptor with atracurium activates FOXO/DAF-16-induced longevity. (nih.gov)
  • Atracurium can be used most advantageously if muscle twitch response to peripheral nerve stimulation is monitored to assess degree of muscle relaxation. (nih.gov)
  • Atracurium: Theophylline decreases the effect of muscle relaxant. (pediatriconcall.com)
  • Atracurium is a muscle relaxant and is used mainly as part of the anaesthetic procedure for surgery. (who.int)
  • Administration of anticholinesterase agents (neostigmine, pyridostigmine) may be used to antagonize the action of atracurium once the patient has demonstrated some spontaneous recovery from neuromuscular block. (drugguide.com)
  • La inducci n fue con tiopental en 16 casos, con etomidato en 298, midazolam en 721 y propofol en 1,259. (medigraphic.com)
  • El mantenimiento fue con halotano en cinco casos, enflurano en siete, propofol en 41, isoflurano en 1,442, sevoflurano en 40 y desflurano en 38. (medigraphic.com)
  • El propofol e isoflurano fueron los agentes anest sicos m s utilizados, las complicaciones metab licas fueron m s comunes en el per odo transanest sico. (medigraphic.com)
  • Indeed, because laudanosine is cleared primarily via renal excretion, a cat study modelling anephric patients went so far as to corroborate that EEG changes, when observed, were evident only at plasma concentrations 8 to 10 times greater than those observed in humans during infusions of atracurium. (wikipedia.org)
  • As with other nondepolarizing neuromuscular blockers, the time to onset of paralysis decreases and the duration of maximum effect increases with increasing atracurium doses. (nih.gov)
  • Repeated administration of maintenance doses of atracurium has no cumulative effect on the duration of neuromuscular block if recovery is allowed to begin prior to repeat dosing. (nih.gov)
  • We also perform custom synthesis and purification of Atracurium Impurity V (Mixture of Diastereomers) impurity from mg to gm scale. (blogspot.com)
  • paromomycin increases effects of atracurium by pharmacodynamic synergism. (medscape.com)
  • The global Atracurium Besylate Market research report is the well-analyzed solution for the decision-makers and academicians who are seeking a detailed analysis in terms of both qualitative as well as quantitative, for the historic period and for the upcoming years forecast. (timestechpharma.com)
  • Fortunately, both for the public and for atracurium, rapid initial investigations irrefutably failed to find any overt or EEG evidence for a connection between atracurium administration and epileptogenic activity. (wikipedia.org)
  • The neuromuscular blocking action of atracurium is enhanced in the presence of potent inhalation anesthetics. (nih.gov)
  • If you are currently taking lorazepam, it is important to let your doctor know before undergoing surgery that may require the use of atracurium or similar medications. (lorazepamum.com)
  • 28 September 2014 - A World Health Organization (WHO) assessment of the cause of the death of 15 children in rural Idleb, northern Syria, has concluded that the most likely cause of the event was the incorrect use of a drug called Atracurium as a diluent for measles/rubella vaccine. (who.int)
  • All evidence available to the assessment team indicates that the incorrect use of Atracurium as a diluent was the cause of the deaths. (who.int)
  • Because atracurium undergoes Hofmann elimination as a primary route of chemodegradation, one of the major metabolites from this process is laudanosine, a tertiary amino alkaloid reported to be a modest CNS stimulant with epileptogenic activity and cardiovascular effects such a hypotension and bradycardia. (wikipedia.org)
  • In some cases, lorazepam may alter the effects of atracurium. (lorazepamum.com)
  • According to Ameco Research's Atracurium Besylate Market report, The analysts took this into account when estimating the Atracurium Besylate Market size and CAGR for the respective industry. (timestechpharma.com)
  • Assess respiratory status continuously throughout therapy with atracurium. (drugguide.com)
  • To avoid distress to the patient, atracurium should not be administered before unconsciousness has been induced. (pfizermedicalinformation.com)
  • Atracurium was approved for medical use in the United States in 1983. (wikipedia.org)