• Scurvy is a state of dietary deficiency of vitamin C (ascorbic acid). (medscape.com)
  • Although scurvy is uncommon, it still occurs and can affect adults and children who have chronic dietary vitamin C deficiency (see the image below). (medscape.com)
  • Plasma ascorbic acid level may help in establishing the diagnosis, but this level tends to reflect the recent dietary intake rather than the actual tissue levels of vitamin C. Signs of scurvy can occur with low-normal serum levels of vitamin C. (medscape.com)
  • In countries with low rates of food insecurity, vitamin C deficiency can occur as part of general undernutrition, but severe deficiency (causing scurvy) is uncommon. (msdmanuals.com)
  • Severe vitamin C deficiency results in scurvy, a disorder characterized by hemorrhagic manifestations and abnormal osteoid and dentin formation. (msdmanuals.com)
  • Symptoms of scurvy (related to defects in connective tissues) develop after a few months of deficiency. (msdmanuals.com)
  • Vitamin C deficiency leads to scurvy. (medscape.com)
  • vitamin C deficiency impairs collagen synthesis and results in the typical signs of scurvy. (medscape.com)
  • The proven and effective use of vitamin C is for treating vitamin C deficiency and conditions that result from it, like scurvy. (webmd.com)
  • Ascorbic acid deficiency frequently develops into SCURVY in young children fed unsupplemented cow's milk exclusively during their first year. (lookformedical.com)
  • For example, vitamin C used to treat scurvy and other deficiency conditions is more effective when given as a natural food concentrate, which includes minerals, rutin and other analogs. (westonaprice.org)
  • Ascorbic acid (Vitamin C). Its deficiency causes scurvy. (trigger-points.org)
  • Scurvy is rarely seen in developed countries and is characterized by deficiency of vitamin C, which can lead to symptoms including wound impairment, bleeding manifestations, and loss of teeth. (towerhealth.org)
  • Although rare, severe vitamin C deficiency causes scurvy. (firstcry.com)
  • Used to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. (pharmacycode.com)
  • Ascorbic Acid (vitamin C) is a water-soluble vitamin indicated for the prevention and treatment of scurvy, as ascorbic acid deficiency results in scurvy. (pharmacycode.com)
  • Scurvy is caused by l -ascorbic acid (vitamin C) deficiency and was common in the 15th century. (neurology.org)
  • It plays a significant role in the metabolism of tyrosine, carbohydrates, iron, folic acid conversion to folinic acid, synthesis of lipids and proteins, resistance to infections and cellular respiration. (affygility.com)
  • painful sore tongue with a smooth appearance -- folate (B-9) deficiency -- try to avoid synthetic folic acid. (naturalnews.com)
  • Extended use of Cycrin may cause deficiencies in folic acid, magnesium, zinc, some B vitamins and C. Supplementation may be helpful with long term use of this medication. (naturalnews.com)
  • Folic acid deficiency, megaloblastic anemia and peripheral polyneuropathy due to oral contraceptives, Isr J Med Sci, 1989, 25 (3): 142-5. (naturalnews.com)
  • Folic acid is the parent compound of a family of naturally occurring derivatives known as folates. (regenerativehealth.co.nz)
  • Folate is the generic term for compounds that exhibit the biological activity of folic acid. (regenerativehealth.co.nz)
  • Dilantin and myselin destroy folic acid. (regenerativehealth.co.nz)
  • Sulphur drugs may interfere with bacteria in the intestine which manufacture folic acid. (regenerativehealth.co.nz)
  • Cobalamin (vitamin B12) and folic acid. (trigger-points.org)
  • Folic acid is found in leafy vegetables instead (hence the name, from the Latin word folium, which means "leaf"), fruits, and liver. (trigger-points.org)
  • Even a moderate vitamin B12 deficiency and its counterpart folic acid, may lead to Alzheimer's disease and other cases of dementia. (ayurtimes.com)
  • Combined folic acid and 12 September 2002. (who.int)
  • Functional genetic variants of glutathione S-transferase protect against serum ascorbic acid deficiency. (cdc.gov)
  • Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta oxidation. (wikipedia.org)
  • Thiamin pyrophosphate (TPP) , the active form of thiamin, is involved in several enzyme functions associated with the metabolism of carbohydrates, branched-chain amino acids, and fatty acids . (reachingfordreams.com)
  • These two vitamins are closely linked and are essential in protein synthesis, production of red blood cells, and in the synthesis of fatty acids and the production of nerve myelin. (trigger-points.org)
  • State the physiological role of lysophospholipids & fatty acids produced by the breakdown of lecithin. (medical-junction.com)
  • 2. Classify the fatty acids in details & indicate their physical properties. (medical-junction.com)
  • Dietary absorption of VITAMIN C is highly dependent upon this class of transporters and a subset of SODIUM GLUCOSE TRANSPORTERS which transport the oxidized form of vitamin C, DEHYDROASCORBIC ACID. (lookformedical.com)
  • Without this glycoprotein, which is essential for absorption of vitamin B12, causes this deficiency. (ayurtimes.com)
  • When absorption process is not occurred properly, it leads to B12 deficiency. (ayurtimes.com)
  • a vitamin C deficiency results in impaired collagen synthesis. (medscape.com)
  • Ascorbic acid also enhances nitric oxide synthesis to improve blood flow, which helps distribute nutrients throughout the body. (purebulk.com)
  • they bleed easily in severe deficiency. (msdmanuals.com)
  • Severe thiamin deficiency leads to beriberi, a disease that affects multiple organ systems, including the central and peripheral nervous systems. (reachingfordreams.com)
  • An acquired blood vessel disorder caused by severe deficiency of vitamin C (ASCORBIC ACID) in the diet leading to defective collagen formation in small blood vessels. (lookformedical.com)
  • We report a case of intravascular hemolysis and methemoglobinemia, precipitated by severe acute respiratory syndrome coronavirus 2 infection, in a patient with undiagnosed glucose-6-phosphate dehydrogenase deficiency. (cdc.gov)
  • However, when stores of vitamin B12 in body reduce further or when deficiency of vitamin B12 becomes severe, the symptoms that often shows up are many. (ayurtimes.com)
  • This study aimed to determine the effects of liposomal iron pyrophosphate/ascorbic acid on clinical and psychological outcomes in pregnant women. (unica.it)
  • G6DP deficiency increases the risk for intravascular hemolysis upon exposure to oxidative agents, such as fava beans, sulfonamides, and hydroxychloroquine, the subject of clinical trials for persons with SARS-CoV-2 infection. (cdc.gov)
  • Janet Travell discovered that often, a subclinical vitamin deficiency causes myofascial problems long before the onset of a clinical deficiency proper. (trigger-points.org)
  • The State recognizes that food fortification is vital where there is a demonstrated need to increase the intake of an essential nutrient by one or more population groups, as manifested in dietary, biochemical or clinical evidences of deficiency. (who.int)
  • Overview of Vitamins Vitamins may be Fat soluble (vitamins A, D, E, and K) Water soluble (B vitamins and vitamin C) The B vitamins include biotin, folate, niacin, pantothenic acid, riboflavin (B2), thiamin (B1). (msdmanuals.com)
  • Riboflavin deficiency can affect multiple pathways in the metabolism of vitamin B6, folate, niacin, and iron. (reachingfordreams.com)
  • Riboflavin deficiency (also called ariboflavinosis) results in stomatitis including painful red tongue with sore throat, chapped and fissured lips (cheilosis), and inflammation of the corners of the mouth. (reachingfordreams.com)
  • Additionally, older people suffering from acute ischemic stroke were found to be deficient for riboflavin, and riboflavin deficiency has been linked to a higher risk of fracture in postmenopausal women with the MTHFR 677T variant. (reachingfordreams.com)
  • This may be a sign of vitamin B2 (riboflavin) deficiency . (naturalnews.com)
  • Other reported gamma-butyrobetaine dioxygenase inhibitors include cyclopropyl-substituted gamma-butyrobetaines and 3-(2,2-dimethylcyclopropyl)propanoic acid, which is a mechanism-based enzyme inhibitor. (wikipedia.org)
  • 7] The enzyme L-gluconolactone oxidase, which would usually catalyze the conversion of L-gluconogammalactone to L-ascorbic acid, is defective due to a mutation or inborn error in carbohydrate metabolism. (medscape.com)
  • An enzyme involved in the metabolism of ASCORBIC ACID and aldarate. (lookformedical.com)
  • An enzyme that converts ascorbic acid to dehydroascorbic acid. (lookformedical.com)
  • Type 1 (also called erythrocyte reductase deficiency) occurs when RBCs lack the enzyme. (medlineplus.gov)
  • Type 2 (also called generalized reductase deficiency) occurs when the enzyme doesn't work in the body. (medlineplus.gov)
  • To a minor extent, the Filipino diet is also deficient in ascorbic acid, calcium and folate. (who.int)
  • Ascorbic acid (vitamin C) is a water-soluble vitamin and an antiscorbutic product that is essential for collagen formulation and tissue repair. (affygility.com)
  • Vitamin C, also known as ascorbic acid, is a water-soluble vitamin. (medscape.com)
  • Water-soluble vitamin, it is essential in energy metabolism and lipid metabolism, and its deficiency causes degeneration of nerve myelin. (trigger-points.org)
  • Also known as, ascorbic vitamin, this water-soluble vitamin is not produced by the body and needs to be consumed in certain amounts. (firstcry.com)
  • Doses up to ascorbic acid 200 mg per day have not been associated with adverse consequences. (medscape.com)
  • Do not stop using ascorbic acid suddenly after long-term use at high doses, or you could have 'conditional' vitamin C deficiency. (everydayhealth.com)
  • Higher doses might be used to treat vitamin C deficiencies. (webmd.com)
  • Ascorbic acid is a potent antioxidant that can also regenerate other antioxidants in the body. (purebulk.com)
  • Like most antioxidants, ascorbic acid has neuroprotective properties. (purebulk.com)
  • As an approach to control micronutrient deficiency, food fortification is addition of a micronutrient, deficiency in the diet, to a food which is widely consumed by a specific at-risk groups. (who.int)
  • ABSTRACT Micronutrient deficiencies exist among women of childbearing age in the United Arab Emir- ates but the effects of maternal micronutrient deficiency on fetal growth are not well documented. (who.int)
  • Being water-soluble, any excess ascorbic acid is easily excreted with water. (wellness-extra.com)
  • Ascorbic acid is prone to oxidation in vivo, and body stores are affected by environmental and lifestyle factors (eg, smoking), biological conditions (eg, inflammation, iron excess), and pathologic conditions (eg, malabsorption) that may alter its oxidation. (medscape.com)
  • Excess amounts of ascorbic acid are excreted unchanged or as metabolites. (medscape.com)
  • Ascorbic acid (Vitamin C) has recovery properties because it plays a vital role in the regulation of the oxidation-reduction processes, carbohydrate metabolism, clotting of the blood, regeneration of the tissues, formation of hormones, and normalization of the capillary permeability. (herbhealer.net)
  • 1 Weininger J, King JC: Effect of oral contraceptive agents on ascorbic acid metabolism in the rhesus monkey, Am J Clin Nutr, 1982, 35(6):1408-16. (naturalnews.com)
  • Its deficiency worsens myofascial syndromes, because on the one hand it takes part in the metabolism of glucose (the fuel of muscles), and because on the other it is essential in the functioning of the nerves. (trigger-points.org)
  • A nutrient essential to human life and health in general, ascorbic acid benefits by being a potential healing or preventive agent for a number of specific illnesses, ranging from the common cold to cancer. (shahzadpurfarmyoga.com)
  • Vitamin C, also known as ascorbic acid, is a water-soluble nutrient that functions as a cofactor for several metabolic functions. (zenithnutrition.com)
  • Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. (lookformedical.com)
  • Maternal micronutrient status affects preg- supplements are routinely prescribed for nancy outcome [ 1,2 ] and maternal micro- the obstetric population, but compliance is nutrient deficiency has been reported to be generally poor. (who.int)
  • Hemodialysis (HD) patients with functional iron deficiency (FID) often develop resistance to recombinant human erythropoietin (rHuEpo). (thestemcellfoundation.com)
  • G6PD deficiency can induce methemoglobinemia by inhibiting NADPH-flavine reductase, which prevents the reduction of methemoglobin. (cdc.gov)
  • Dietary deficiencies are known to cause several diseases that manifest as oral changes. (medscape.com)
  • It is the lactone of 2,3-DIKETOGULONIC ACID and has antiscorbutic activity in man on oral ingestion. (lookformedical.com)
  • 1 Rivers JM: Oral contraceptives and ascorbic acid, Am J Clin Nutr, 1975, 28(5):550-4. (naturalnews.com)
  • Vitamin C deficiency and its manifestations are a consequence of inadequate dietary intake. (zenithnutrition.com)
  • Preventing and controlling iron deficiency are also addressed in Nutrition and Your Health: Dietary Guidelines for Americans (14). (cdc.gov)
  • A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. (lookformedical.com)
  • These critics contend that minimum daily requirements are sufficient to prevent acute deficiencies but not enough to support optimum health, especially as individual requirements for specific vitamins and minerals vary widely. (westonaprice.org)
  • One of the perpetuating factors in myofascial syndromes that is often underestimated, is the deficiency of some vitamins and minerals. (trigger-points.org)
  • Testing of patient with G6PD deficiency and SARS-CoV-2 infection, United Kingdom. (cdc.gov)
  • Methylene blue may be unsafe in people who have or may be at risk for a blood disease called G6PD deficiency . (medlineplus.gov)
  • If you or your child has G6PD deficiency, always tell your provider before getting treatment. (medlineplus.gov)
  • Diagnosis of vitamin C deficiency is usually made clinically in a patient who has skin or gingival signs and is at risk of vitamin C deficiency. (msdmanuals.com)
  • Signs of Vitamin C deficiency can be vague but do exist. (firstcry.com)
  • Iron deficiency is the most common known form of nutritional deficiency. (cdc.gov)
  • Effect of ascorbic acid on desferrioxamine-induced urinary iron excretion in idiopathic hemochromatosis. (webmd.com)
  • Gamma-butyrobetaine dioxygenase also catalyses the oxidation of mildronate to form multiple products including malonic acid semialdehyde, dimethylamine, formaldehyde and (1-methylimidazolidin-4-yl)acetic acid, which is proposed to be formed via a Stevens rearrangement mechanism. (wikipedia.org)
  • They are produced commercially, usually as the first step in the production of nitric acid, either by the direct oxidation of atmospheric nitrogen in the electric arc (Birkeland-Eyder Process) or by the catalytic oxidation of anhydrous ammonia (Oswald Process). (cdc.gov)
  • Membrane transport proteins that actively co-transport ASCORBIC ACID and sodium ions across the CELL MEMBRANE. (lookformedical.com)
  • Vitamin B12 is essential for transforming homocysteine into methionine, which is an important amino acid necessary for synthesizing proteins. (ayurtimes.com)
  • The Hp 2-2 polymers are less efficient inhibitors of hemoglobin-driven oxidative stress, leading to ascorbic acid depletion. (medscape.com)
  • Congestive cardiomyopathy and haemochromatosis--rapid progression possibly accelerated by excessive ingestion of ascorbic acid. (webmd.com)
  • Iron overload associated with congenital pyruvate kinase deficiency and high dose ascorbic acid ingestion. (webmd.com)
  • Many individuals opt to take ascorbic acid powder to maximize the benefits of vitamin C, as it provides better dosing control and more consistent results. (purebulk.com)
  • In adults, symptoms of vitamin C deficiency develop after weeks to months of vitamin C depletion. (msdmanuals.com)
  • There are particular groups especially at risk of vitamin and mineral deficiencies, particularly the elderly, pregnant and lactating women, heavy consumers of alcohol and drugs, those who follow long-term diets very restricted and totally devoid of food of animal origin (unless supplemented very carefully), the chronically ill and people taking certain medications. (trigger-points.org)
  • If one consumes too much alcohol, lives in a polluted city, regularly takes medication containing salicylic acid derivatives, smokes, and lives under a lot of stress, then it is recommended to increase the daily dose of vitamin C to 5-10 grams. (wellness-extra.com)
  • In higher plants, salicylic acid (SA) plays important roles in inducing resistance to biotic and abiotic stresses. (biomedcentral.com)
  • [ 2 ] However, limited studies have suggested that levels greater than 3 mg/dL may be associated with uricosuria and, in persons with glucose-6-phosphatase deficiency, may induce red blood cell fragility. (medscape.com)
  • Glucose 6‐phosphate dehydrogenase (G6DP) deficiency is an X-linked enzymatic disorder that affects 400 million persons worldwide and has a high prevalence (5%-20%) in African and Asian populations ( 2 ). (cdc.gov)
  • The typical pathologic manifestations of vitamin C deficiency, including poor wound healing, are noted in collagen-containing tissues and in organs and tissues such as skin, cartilage, dentine, osteoid, and capillary blood vessels. (medscape.com)
  • Global Vitamin C Status and Prevalence of Deficiency: A Cause for Concern? (mdpi.com)
  • In the United States, the prevalence of iron-deficiency anemia among children declined during the 1970s in association with increased iron intake during infancy (1-3). (cdc.gov)
  • Ascorbic acid is a physiological antioxidant that protects cells by suppressing free radical damage. (purebulk.com)
  • At Tufts University, researchers had found int wo large studies that people over the age of 60 who had the most ascorbic acid in their blood also had the highest level of HDL cholesterol, the protective cholesterol associated with freedom from heart disease. (shahzadpurfarmyoga.com)
  • However, if the daily intake of vitamin C was increased from 50 to 500 milligrams, the ascorbic acid levels within the blood plasma doubled, and they doubled yet again when 5 grams daily was reached. (wellness-extra.com)
  • High blood pressure can be remedied with lots of ascorbic acid and L-lysine daily . (naturalnews.com)
  • A blood film for the patient showed normochromic normocytic erythrocytes and a few hemighost cells ( Figure , panel A). A 2-stage G6DP assay confirmed G6DP deficiency (0.8 IU/g hemoglobin). (cdc.gov)
  • Ascorbic acid helps promote the production of infection-fighting white blood cells, and it may enhance the function of these white blood cells by protecting them from free radicals. (purebulk.com)
  • Vitamin B12 deficiency symptoms show up first in blood and later in the nervous system of the body. (ayurtimes.com)
  • Vitamin B12 deficiency is due to inadequate stores of vitamin B12 in human body. (ayurtimes.com)
  • Outside of the myofascial scope, I would like to stress that vitamin deficiencies in the modern diet are also associated with serious diseases such as cancer. (trigger-points.org)
  • Vitamin B12 deficiency can show up several symptoms and when not treated can further lead to various diseases. (ayurtimes.com)
  • Most cases of this deficiency are due to intestinal diseases but not due to lack of B12 from diet. (ayurtimes.com)
  • On contact with moisture, nitrogen dioxide forms a mixture of nitric and nitrous acids. (cdc.gov)
  • Trace metal impurities most likely cause nitrogen oxides to form in nitric acid and its solutions. (cdc.gov)
  • Comment: Ascorbic acid increases the availability of iron for chelation with deferoxamine. (medscape.com)
  • In children, iron deficiency causes developmental delays and behavioral disturbances, and in pregnant women, it increases the risk for a preterm delivery and delivering a low-birthweight baby. (cdc.gov)
  • Vitamin C levels of less than 0.3 mg/dL indicate significant deficiency, while levels that exceed 0.6 mg/dL indicate sufficient intake. (medscape.com)
  • Meat, fish and milk have sufficient ascorbic acid content. (firstcry.com)