Artificial cells. Medical search. Frequent questions

According to the Regional Research Reports, the global ?stem cell artificial meat market size is estimated to grow from a million USD in 2022 to reach multi-million USD by 2033 at a CAGR of 9.4% from 2023 to 2033. (regionalresearchreports.com)
The Regional Research Reports published the report on "global ?stem cell artificial meat market Report 2023 - Future Growth Opportunities, Latest Technological Trends, In-depth Analysis, and Forecast To 2033" provides the futuristic vision of the global ?stem cell artificial meat market along with the market size (Revenue - US$ Million) and estimates for the duration 2023 to 2033. (regionalresearchreports.com)
Allogeneic pancreatic islet cellular therapy produced from deceased donor pancreatic cells received FDA approval in June 2023. (medscape.com)

The result was the creation of bacterial cells that can be trained using artificial intelligence algorithms. (innovationtoronto.com)
Artificial Intelligence algorithms allowed the scientists to produce the required genetic modifications to the bacterial cells at a significantly reduced time and cost. (innovationtoronto.com)
Using artificial intelligence algorithms, the group succeeded in harnessing this natural ability to make an analog-to-digital converter - a cell capable of reporting whether the concentration of a particular molecule is "low", "medium", or "high. (innovationtoronto.com)
No content on this site may be used to train artificial intelligence systems without permission in writing from the MIT Press. (mit.edu)
Recent advances in artificial intelligence, particularly in the field of deep learning, have enabled researchers to create compelling algorithms for medical image analysis. (uni-linz.ac.at)
Dr. Gregg, a NYSCF - Robertson Neuroscience Investigator Alumnus and University of Utah Associate Professor of Neurobiology and Human Genetics, has co-developed an artificial intelligence-driven platform called Storyline with leaders in AI and telehealth software. (nyscf.org)
Storyline is a platform technology that uses artificial intelligence to identify health issues through analyses of micro-features of behavioral and emotional characteristics captured through a smartphone app. (nyscf.org)
Each questionnaire - developed with input from experts in medicine, artificial intelligence, and psychology - only takes about 10 minutes to complete, and users will be prompted three times over a few weeks to respond to key questions. (nyscf.org)
These recordings are then analyzed using artificial intelligence, in which an algorithm dissects subtle, yet telling characteristics to determine whether someone may need to seek treatment. (nyscf.org)
Development of novel tools and methods for studying lysosome-dependent cell death Artificial intelligence applications in biomedical science 1. (lu.se)
Use of artificial intelligence for biomedical image analysis 2. (lu.se)
Use of artificial intelligence for protein function and structure prediction and modelling 3. (lu.se)
Use of artificial intelligence for integrating biomedical "big data" such as proteomics and genomics datasets Besides our core areas we are involved in several collaborations and research networks. (lu.se)
Can generative artificial intelligence help clinicians better manage patient messages? (kevinmd.com)
Researchers from the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig and the Kavli Institute for Systems Neuroscience in Trondheim have now developed software that uses artificial intelligence to directly predict eye position and eye movements from MRI images. (mpg.de)
The DeepMReye software uses artificial intelligence to directly predict eye position and eye movements from MRI images. (mpg.de)
Artificial intelligence helps a lot here, because we often don't know exactly which patterns to look for as scientists', Markus Frey explains. (mpg.de)
Here too, studies can be carried out more easily with DeepMReye, as the artificial intelligence can be calibrated with the help of healthy subjects and then be applied in examinations of blind patients. (mpg.de)
A new application of artificial intelligence could help researchers solve medical mysteries ranging from cancer to Alzheimer's. (acm.org)
The world of artificial intelligence has exploded in recent years. (acm.org)
Language models like ChatGPT, which use artificial intelligence (AI) and natural language processing , generate human -like text that can aid researchers . (bvsalud.org)
New developments in artificial intelligence (AI), for example, have expanded the use and accessibility of 'smart' computers and machines. (cdc.gov)

A main reason for this is the premature dysfunction of these immune cells, which have been artificially modified in vitro. (unige.ch)
The present study had aimed to evaluate the effect of a feeder layer of irradiated MSCs in the in vitro expansion of NK cells. (springer.com)
The researchers discovered that the protocells were able to produce energy-rich molecules (ATP) via glycolysis and synthesize RNA and proteins by in vitro gene expression, indicating that the inherited bacterial components remained active in the synthetic cells. (nanowerk.com)
We conducted further experiments on each potential reprogramming factor and narrowed the list down to four factors that would transform mesenchymal cells into basal keratinocytes in vitro in petri dishes. (singularityhub.com)
Although some artificial cells have proven successful for producing therapeutics or performing in vitro specific reactions, they have not been investigated in vivo to determine whether they preserve their architecture and functionality while avoiding toxicity. (nih.gov)
In vitro models of primary human osteocytes embedded in natural mineralized matrix without artificial scaffolds are lacking. (ntnu.no)
This resemblance to native bone indicates a model system with potential for studying osteocyte-like cell differentiation, cross-talk between bone cells, and the mineralization process in a bonelike structure in vitro without artificial scaffolds. (ntnu.no)
In vitro large amplification of tumor-specific cytotoxic T lymphocytes (CTLs) and adoptive transfer of these cells is one of the most promising approaches to treat malignant diseases in which an effective immune response is not achieved by active immunization. (ewha.ac.kr)
However, generating sufficient numbers of tumor-specific CTLs stimulated with autologous antigen presenting cells (APCs) in vitro is one of the most problematic steps in the adoptive cell transfer (ACT) therapy. (ewha.ac.kr)
Our results show that TRP-2-specific CD8 + T cells elicited by immunization with recombinant adenovirus expressing the mini-gene epitope are efficiently stimulated and amplified in vitro to a greater extent by aAPCs than by natural splenic APCs. (ewha.ac.kr)
These results demonstrate that prior in vivo immunization, which increases the precursor frequency, simplifies posterior expansion of tumorspecific CD8 + T cells, and aAPCs is superior to autologous APC for in vitro amplification. (ewha.ac.kr)
Cell immortalization is a crucial technique in artificial meat production, as it enables the perpetual growth and replication of animal cells required to generate meat in vitro. (amzeal.com)
Appropriate cell-free in vitro models are needed to study bioavailability of a material in a target biological compartment. (cdc.gov)
The researched acrylic teeth developed cytotoxicity against the cells in vitro during the time periods of 24, 48, and 72 hours, while Ivoclar Vivodent and Trilux brands of teeth developed cytotoxicity against the tested cells during the time period of 168 hours. (bvsalud.org)

Technion and MIT collaborate to transform bacterial cells into living artificial neural circuits. (innovationtoronto.com)
Graduate students and researchers from Technion - Israel Institute of Technology Professor Ramez Daniel's Laboratory for Synthetic Biology & Bioelectronics worked together with Professor Ron Weiss from the Massachusetts Institute of Technology to create genetic "devices" designed to perform computations like artificial neural circuits. (innovationtoronto.com)
The research group designed the plasmid's genetic sequence to function as a simple computer, or more specifically, a simple artificial neural network. (innovationtoronto.com)
The Ph.D students (now doctors) Luna Rizik and Loai Danial, together with Dr. Mouna Habib, under the guidance of Prof. Ramez Daniel from the Faculty of Biomedical Engineering at the Technion, and in collaboration with Prof. Ron Weiss from the Synthetic Biology Center, MIT, were inspired by how artificial neural networks function. (innovationtoronto.com)
Histological slides of basal cell carcinomas (BCCs), the most frequent skin tumor, are accessed by pathologists on a daily basis and are therefore well suited for automated prescreening by neural networks for the identification of cancerous regions and swift tumor classification. (uni-linz.ac.at)
In this proof-of-concept study, we implemented an accurate and intuitively interpretable artificial neural network (ANN) for the detection of BCCs in histological whole-slide images (WSIs). (uni-linz.ac.at)
H. Ritter, Learning with the self-organizing map, in: T. Kohonen (Ed.), Artificial Neural Networks, Vol. 1, Elsevier, Amsterdam, 1991. (crossref.org)
Synapses are neural connections that allow nerve cells to communicate with one another and manage thousands of tasks. (techquila.co.in)

We present a novel and efficient non-integrating gene expression system in human embryonic stem cells (hESc) utilizing human artificial chromosomes (HAC), which behave as autonomous endogenous host chromosomes and segregate correctly during cell division. (nih.gov)
The particular stem cells that will eventually make the future body, the embryonic stem cells (ESCs) cluster together inside the embryo towards one end: this stage of development is known as the blastocyst. (cam.ac.uk)
We think that it will be possible to mimic a lot of the developmental events occurring before 14 days using human embryonic and extra-embryonic stem cells using a similar approach to our technique using mouse stem cells," she says. (cam.ac.uk)

Scientists can encapsulate biomolecules in cell-sized phospholipid vesicles and by doing so, observe these molecules to act similarly as in biological cells and thereby recreate certain cell functions. (wikipedia.org)
Using a similar pressure-regulating mechanism to that found in cells, scientists created an artificial cell that responds to a sudden and possibly catastrophic change in its surroundings. (sciencedaily.com)
Scientists at the University of Cambridge have managed to create a structure resembling a mouse embryo in culture, using two types of stem cells - the body's 'master cells' - and a 3D scaffold on which they can grow. (cam.ac.uk)
Scientists in Western Switzerland have discovered how to improve the anti-tumour power of CAR-T cells, artificial immune ''super-cells'' used against blood cancers. (unige.ch)
To investigate the role of reductive carboxylation, the scientists inhibited this mechanism in CAR-T cells in mouse models of leukaemia and multiple myeloma, two blood cancers. (unige.ch)
Nanowerk News ) Scientists have harnessed the potential of bacteria to help build advanced synthetic cells which mimic real life functionality. (nanowerk.com)
Bringing together concepts from electrical engineering and bioengineering tools, Technion and MIT scientists collaborated to produce cells engineered to compute sophisticated functions - "biocomputers" of sorts. (innovationtoronto.com)
And, scientists are now using stem cells to create human cells with biological components. (nutsel.com)
In another work, published on Cell.com, scientists claimed that they had successfully grown monkey embryos containing human cells for the first time - the latest milestone in a rapidly advancing field that has drawn ethical questions. (nutsel.com)
To study human development in a dish, scientists have already developed stem cell models for various embryonic and extraembryonic cell types. (nutsel.com)
The scientists used human stem cells, which can still grow into every type of cell in an embryo, to make the model cells. (nutsel.com)
Apart from this, another similar feat has been achieved by the scientists at MIT, who came up with a chip with artificial synapses. (techquila.co.in)
Scientists are also working on superconductor computing chips which is the next step in the development of artificial neurons. (techquila.co.in)
With LOCKR, a switch-like protein, scientists can finally build the biological equivalent of such circuits inside cells. (ucsf.edu)

But the disease history of the patient, in combination with the amplification process, exhausts the cells: they reach a state of terminal differentiation that precipitates the end of their life cycle without leaving them time to act on the length. (unige.ch)
The state of differentiation of CAR-T cells is therefore a key factor in the success of the treatment. (unige.ch)
2016). Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cells. (springer.com)
The present invention provides methods to promote the differentiation of pluripotent stem cells. (patsnap.com)
The present invention also provides methods to promote the differentiation of pluripotent stem cells without the use of a feeder cell layer. (patsnap.com)
Methods of identifying differentiation factors capable of promoting the differentiation of endoderm cells, such as PDX1-positive foregut endoderm cells and PDX1-negative definitive endoderm cells, are also disclosed. (patsnap.com)
In addition to osteocyte-like cells, the spheroids consisted of osteoblasts at various differentiation stages surrounded by a rim of cells resembling lining cells. (ntnu.no)

Nov. 10, 2022 Researchers have discovered a new process that uses fuel to control non-living materials, similar to what living cells do. (sciencedaily.com)
While this artificial embryo closely resembles the real thing, it is unlikely that it would develop further into a healthy foetus, say the researchers. (cam.ac.uk)
Previous attempts to model protocells using microcapsules have fallen short, so the team of researchers turned to bacteria to build complex synthetic cells using a living material assembly process. (nanowerk.com)
As a step towards the construction of a synthetic/living cell entity, the researchers implanted living bacteria into the protocells to generate self-sustainable ATP production and long-term energization for glycolysis, gene expression and cytoskeletal assembly. (nanowerk.com)
Researchers have created a two-layer solar cell that's the most efficient yet among cells made of organic materials. (sciencenews.org)
Inspired by the efficiency with which plants convert sunlight into sugar, researchers have fabricated a solar cell that uses photosynthetic proteins to convert light into electricity. (sciencenews.org)
Given the fluid's incompressibility, those forces can give rise to what the researchers call a "swirling" instability, and the flow switches to a cell-spanning rotation. (aps.org)
Researchers have reproduced the wafting motion of hair-like structures on cell surfaces with tiny magnetic rods and a rotating magnetic field. (aps.org)
In 2008, for example, British researchers claimed that they had created embryos and stem cells using human cells and the egg cells of cows, but said such experiments would not lead to hybrid human-animal babies or even direct medical therapies. (nutsel.com)
In such cases, researchers may isolate skin stem cells from a patient , grow them in the laboratory and transplant them back into the patient. (singularityhub.com)
Researchers establish connections between Alzheimer's-linked genetic alterations and the functioning of brain cells. (medindia.net)
Researchers devised "smart" cells that behave like tiny autonomous robots which may be used to detect damage and disease, and deliver help at just the right time and in just the right amount. (ucsf.edu)
In the first of the two new papers, the researchers describe arms that can direct molecular traffic inside cells, degrade specific proteins, and initiate the cell's self-destruct process. (ucsf.edu)
Researchers have used lasers to connect, arrange and merge artificial cells, paving the way for networks of artificial cells that act like tissues. (healthwnews.com)
Now, researchers from Imperial College London and Loughborough University have demonstrated a new level of complexity with artificial cells by arranging them into basic tissue structures with different types of connectivity. (healthwnews.com)
The artificial cells have a membrane-like layer as their shell, which the researchers engineered to 'stick' to each other. (healthwnews.com)
The Physical Cell Biology Subgroup of the Biophysical Society is hosting a virtual mini symposium aimed at connecting early career researchers who apply physical principles to gain a deeper mechanistic understanding of cell biology at different. (biophysics.org)
A key component of this innovative technology is cell immortalization, a process that allows researchers to propagate and maintain a continuous source of animal cells for meat production. (amzeal.com)
Researchers at the University of Illinois at Chicago have engineered a potentially game-changing solar cell that cheaply and efficiently converts atmospheric carbon dioxide directly into usable hydrocarbon fuel, using only sunlight for energy. (eurekalert.org)

The invention provides an artificial antigen presenting cell (AAPC) comprising a eukaryotic cell expressing an antigen presenting complex comprising a human leukocyte antigen (HLA) molecule of a single type, at least one exogenous accessory molecule and at least one exogenous T cell-specific epitope. (patsnap.com)
To circumvent this problem, we have developed an artificial antigen presenting complex (aAPCs) using MHC class I molecules loaded with a melanoma-specific TRP-2 peptide epitope. (ewha.ac.kr)

For instance, when the level of dissolved nutrient molecules (e.g., sugar) in the cell's watery environment drops, water flows into the cell through osmosis. (sciencedaily.com)
Protein channels in the cell's membrane release the excess water, preventing catastrophic expansion and bursting of the cell. (sciencedaily.com)
With each pulse, a bit of the excess contents were released and a cyclical breathing-like change in the artificial cell's texture was produced. (sciencedaily.com)
During a fruit-fly egg cell's early development, its internal fluid begins to swirl in a vortex-a transition caused by the coordinated behavior of elastic filaments in the cell. (aps.org)
The cell's internal fluid motion transitions from a disordered mix of small-scale flows to a single vortex that encompasses the entire cell. (aps.org)
MFs inherit the donor cell's natural cytoplasm and membrane, while the AOs house reactive components and provide cell-like architecture and functionality. (nih.gov)

Specific recent and current research topics that contribute to the synthetic biology toolbox for development of artificial cells include membrane texturing through phase separation, artificial DNA adhesion receptors, hybrid lipid-polymer membrane systems for enhanced stability and lifetime, encapsulation of feedback-responsive systems and controlled generation of eukaryote-like membrane architectures. (royalsociety.org)
Several patient populations are awaiting the development of artificial blood vessels. (dukehealth.org)

In earlier studies, the development of snoRNA expression vectors was one of the main approaches to study the influence of box C/D snoRNAs on target genes in mammalian cells. (hindawi.com)
New vector for transfer of yeast artificial chromosomes to mammalian cells. (ox.ac.uk)
A modification vector has been constructed to facilitate the transfer of yeast artificial chromosomes (YACs) to mammalian cells in culture by targeting a dominant selectable marker (G418 resistance) to the right arm of pYAC4 clones. (ox.ac.uk)

To fit into the tiny cell nucleus, it is condensed around proteins called histones. (unige.ch)
In this prototype solar cell, photosynthetic proteins (spheres embedded in yellow peptides) absorb light and pump electrons (e-) into a silver electrode. (sciencenews.org)
To make the solar cell, a team of biologists and engineers led by Marc Baldo of the Massachusetts Institute of Technology (MIT) harvested photosynthetic proteins from spinach and the bacterium Rhodobacter sphaeroides and deposited the proteins onto a glass support. (sciencenews.org)
Because the proteins naturally reside in an aqueous environment inside a cell membrane, it took some creative chemistry to keep the approximately 2 billion isolated proteins functional on a solid surface. (sciencenews.org)
Biologists have long recognized that cellular fluid is stirred by molecular motor proteins marching along a network of cell-spanning microtubules, but the cause of the vortex flow transition has remained unclear. (aps.org)
To do so, we compared the levels of different proteins inside the two cell types to figure out what distinguished them and find out what we would need to change in order to reprogram one cell type into the other. (singularityhub.com)
By reinserting biological components such as proteins in the membrane, we could get the cells to communicate and exchange material with one another. (healthwnews.com)

Although the prototype device can't yet rival commercial solar cells made of silicon, it demonstrates a new strategy for making longer-lasting photovoltaic cells. (sciencenews.org)

After that, we inject the endothelial cells into the lumen of the blood vessel. (dukehealth.org)
This strategy utilizes bioengineered cell sheets containing vascular endothelial cells and a microvascular bed supplied by blood vessels that can be anastomosed to those of a host. (heraldopenaccess.us)
Another method of promoting capillary angiogenesis involves co-culture with vascular endothelial cells that directly contribute to blood vessel formation. (heraldopenaccess.us)
Other approaches have cultured vascular endothelial cells in scaffolds containing microfluidic channels or decellularized organs, but seeding cells within these 'vascular' structures is difficult, and this method cannot generate tissues with a high cell density. (heraldopenaccess.us)
We are now able to fabricate cell sheets using cardiomyocytes and endothelial cells differentiated from human induced Pluripotent Stem (iPS) cells and are aiming to use our technology to create human 3D tissue with cardiac functionality. (heraldopenaccess.us)

Some stricter definitions are based on the assumption that the term "cell" directly relates to biological cells and that these structures therefore have to be alive (or part of a living organism) and, further, that the term "artificial" implies that these structures are artificially built from the bottom-up, i.e. from basic components. (wikipedia.org)
However, in other cases, the term "artificial" does not imply that the entire structure is man-made, but instead, it can refer to the idea that certain functions or structures of biological cells can be modified, simplified, replaced or supplemented with a synthetic entity. (wikipedia.org)
The term "artificial cell" is also used for structures with direct applications such as compartments for drug delivery. (wikipedia.org)
For those creating materials with new properties, such as greater strength or self-healing, the artificial cells ability to sense a possibly damaging event and respond shows an option for changing material structures in response to stress. (sciencedaily.com)
Organ-like structures have been synthesized on a small scale, but overcoming current problems with cell sourcing and scalability will facilitate the creation of cardiac assist devices and organs for transplantation. (heraldopenaccess.us)
The team say that by altering artificial cell membranes they can now get the cells to stick together like 'stickle bricks' - allowing them to be arranged into whole new structures. (healthwnews.com)
These structures could be used to perform functions like initiating chemical reactions or moving chemicals around networks of artificial and biological cells. (healthwnews.com)

CAR-T cell immunotherapy involves taking immune cells - usually T lymphocytes - from a person suffering from cancer, modifying them in the laboratory to increase their ability to recognise and fight tumour cells, then readministering them to the patient. (unige.ch)
NK cells have been seen as potential agents in adoptive immunotherapy for cancer. (springer.com)
Natural killer cell adoptive immunotherapy: Coming of age. (springer.com)
Methods of obtaining an expanded number of TIL from a mammal for adoptive cell immunotherapy are also provided. (patsnap.com)

FDA also approves so-called biologics, which include products made from human tissues, blood, and cells, and gene therapy techniques. (newstimenow.com)
Here, we describe a novel strategy that overcomes the limitation of passive diffusion by introducing functional capillaries into artificial tissues. (heraldopenaccess.us)
Although cell-based therapies (injection of cell suspensions) and regenerative therapies (transplantation of bioengineered tissues) have already been applied clinically, the treatment of serious diseases will require the fabrication of artificial Three-Dimensional (3D) tissues and organs that can be transplanted instead of donor organs. (heraldopenaccess.us)
The development of a novel method of introducing functional vascular networks into artificial tissues will facilitate the creation of thick 3D tissues/organs that are cell-dense and vascular-rich (e.g., cardiac, hepaticorrenal tissue). (heraldopenaccess.us)
Although the slow release of angiogenic factors from a cell scaffold can promoteangiogenesis after transplantation, this approach cannot generate thick tissues because of the long time required for sufficient vascular network formation. (heraldopenaccess.us)
Cells are the basic units of biology, which are capable of working together as a collective when arranged into tissues. (healthwnews.com)
This mimics what is seen in nature, so it's a great step forward in creating biological-like artificial cell tissues. (healthwnews.com)

Until now, most attempts to create an artificial cell have only created a package that can mimic certain tasks of the cell. (wikipedia.org)
Here, these limitations are overcome and customizable cell mimic is achieved-molecular factories (MFs)-by supplementing giant plasma membrane vesicles derived from donor cells with nanometer-sized artificial organelles (AOs). (nih.gov)

The main hurdles foreseen and encountered with this proposed protocell are the creation of a minimal synthetic DNA that holds all sufficient information for life, and the reproduction of non-genetic components that are integral in cell development such as molecular self-organization. (wikipedia.org)
Understanding of molecular mechanisms in natural killer cell therapy. (springer.com)
They developed a continuum model that treats the dense array of microtubules as a deformable porous medium and showed how molecular motors translating along microtubules lead to inward-pointing forces on the fluid in the cell. (aps.org)
Deciphering the molecular machinery of lysosome-dependent cell death and its interactions with other cell death and survival processes 2. (lu.se)
Molecular and materials predictions of emerging solar energy technologies including Dye-Sensitized Solar Cells (DSSCs), Organic Photovoltaics (OPVs), nanoscale energy converters, Light-emitting materials, as well as Solar Fuels including Artificial Photosynthesis. (lu.se)

An artificial cell, synthetic cell or minimal cell is an engineered particle that mimics one or many functions of a biological cell. (wikipedia.org)
The procedure performed by artificial synapse mimics the natural ones. (techquila.co.in)
It is further demonstrated that in a zebrafish vertebrate animal model, these cell mimics show no apparent toxicity and retain their integrity and function. (nih.gov)

NK expansion and activation were stimulated by culture with artificial antigen-presenting cells (aAPCs) and IL-2, in the presence or absence of BM-MSCs. (springer.com)
Efficient stimulation and proliferation of antigen-specific T cells was also confirmed using ovalbumin peptide-loaded aAPCs and OT-I TCR transgenic cells. (ewha.ac.kr)

Artificial neurons however, detect the chemical signals first and then transmit electrical signals further from cell to cell. (techquila.co.in)
Artificial neurons are made of conductive polymers and can communicate over large distances. (techquila.co.in)
These are artificial neurons that are made of superconductors and are much faster than human neurons! (techquila.co.in)

Mar. 16, 2022 Biological processes such as wound healing and cancer cell invasion rely on the collective and coordinated motion of living cells. (sciencedaily.com)
Inasmuch as artificial box C/D RNAs decreased viability of transfected human cells, we propose that natural snoRNAs as well as their artificial analogues can influence the maturation of complementary pre-mRNA and can be effective regulators of vital cellular processes. (hindawi.com)
Synthetic biology aims (among other goals) to harness these processes, to synthesize the switches and program the genes that would make a bacterial cell perform complex tasks. (innovationtoronto.com)
Being able to "computerize" these processes within the cell could have major implications for biomanufacturing and have multiple medical applications. (innovationtoronto.com)
You don't make a new human cell type every day ," Pasque said, and also asserted that they are very excited because now they can study processes that normally remain inaccessible during development. (nutsel.com)
Compositions of cells having specific phenotypic properties produced by these processes are further provided. (patsnap.com)
Furthermore, the extra 90 nanoseconds opens the possibility of filming living images of the processes occurring within cells, for example when a drug attacks an illness. (medindia.net)
Much is still not understood about how gene regulatory interactions control cell fate decisions in single cells, in part due to the difficulty of directly observing gene regulatory processes in vivo. (nature.com)
Gene regulation is one of the key processes that underlie the complex behavior of biological systems, allowing cells to adapt to varying environments, and allowing multi-cellular organisms to express a large number of phenotypically distinct cell types from a single genotype. (nature.com)
The unique advantages of highly varied composition, multicompartmentalized architecture, and preserved functionality in vivo open new biological avenues ranging from the study of biorelevant processes in robust cell-like environments to the production of specific bioactive compounds. (nih.gov)

The DNA (nucleus) of each cell is shown in blue. (nutsel.com)
Green is keratinocytes, red is mesenchymal cells, blue is the cell nucleus and magenta marks the innermost layer of skin epithelium. (singularityhub.com)

My laboratory at the Salk Institute focuses on developing stem-cell-based approaches to "reprogram" cells from one type into another for the purpose of regenerative medicine . (singularityhub.com)
Professor Oscar Ces, also from the Department of Chemistry at Imperial, said: "Connecting artificial cells together is a valuable technology in the wider toolkit we are assembling for creating these biological systems using bottom-up approaches. (healthwnews.com)

Second, while methods such as flow cytometry, smFISH, and single-cell RNA-seq provide snapshots of gene expression distributions across single cells (see e.g. refs. (nature.com)

The three primary elements of such artificial cells are the formation of a lipid membrane, DNA and RNA replication through a template process and the harvesting of chemical energy for active transport across the membrane. (wikipedia.org)
The authors provide original points of view on all types of commercially available micro fuel cells types, including micro proton exchange membrane fuel cells, micro direct methanol fuel cells, micro solid oxide fuel cells and micro bio-fuel cells. (azocleantech.com)

NK cell proliferation, phenotypic expression and cytotoxic activity were evaluated. (springer.com)
The present invention relates generally to methods for stimulating cells, and more particularly, to a novel method to concentrate and/or stimulate cells that maximizes stimulation and/or proliferation of such cells. (patsnap.com)
In the various embodiments, cells are stimulated and concentrated with a surface yielding enhanced proliferation, cell signal transduction, and/or cell surface moiety aggregation. (patsnap.com)

The other two types of stem cell in the blastocyst are the extra-embryonic trophoblast stem cells (TSCs), which will form the placenta, and primitive endoderm stem cells that will form the so-called yolk sac, ensuring that the foetus's organs develop properly and providing essential nutrients. (cam.ac.uk)
It might seem odd, but one of the central challenges when taking pictures of cells and organs, is to avoid noise. (medindia.net)

Stem cell research has the transformative potential to revolutionize medicine . (bvsalud.org)
This study assesses Chat Generative Pre-Trained Transformer (ChatGPT)'s utility in stem cell research and evaluates the accuracy of its references. (bvsalud.org)
Despite these challenges, ChatGPT has the potential to be a valuable tool for stem cell research . (bvsalud.org)

As such, in the area of synthetic biology, an artificial cell can be understood as a completely synthetically made cell that can capture energy, maintain ion gradients, contain macromolecules as well as store information and have the ability to replicate. (wikipedia.org)
In biology, cells use a variety of mechanisms to deal with sudden changes in their surroundings. (sciencedaily.com)
International Journal of Biochemistry & Cell Biology, 40 , 2335-2340. (springer.com)
Natural killer cell biology: An update and future directions. (springer.com)
This provides an unprecedented level of control over the way the protein interacts with other components of the cell, and will allow us to begin tackling unsolved - and previously unsolvable - problems in biology, with important implications for medicine and industry. (ucsf.edu)

The genetic material was inserted into the bacterial cell in the form of a plasmid: a relatively short DNA molecule that remains separate from the bacteria's "natural" genome. (innovationtoronto.com)
They created synthetic computation circuits by combining existing genetic "parts," or engineered genes, in novel ways, and implemented concepts from neuromorphic electronics into bacterial cells. (innovationtoronto.com)
The group were able to create flexible bacterial cells that can be dynamically reprogrammed to switch between reporting whether at least one of a test chemicals, or two, are present (that is, the cells were able to switch between performing the OR and the AND functions). (innovationtoronto.com)

This is the first report of successfully generating gene expressing de novo HAC in hESc, and is a significant step towards the genetic manipulation of stem cells and potential therapeutic applications. (nih.gov)
To expand understanding of the role of snoRNAs in control of gene expression, in this study we tested the ability of artificial box C/D RNAs to affect the maturation of target pre-mRNA. (hindawi.com)
We introduce here a novel integrated setup consisting of a microfluidic chip and accompanying analysis software that enable long-term quantitative tracking of growth and gene expression in single cells. (nature.com)
The dual-input Mother Machine (DIMM) chip enables controlled and continuous variation of external conditions, allowing direct observation of gene regulatory responses to changing conditions in single cells. (nature.com)
In spite of more than half a century of intense study since the discovery of the basic mechanism of gene regulation 1 , much remains to be understood about the ways in which gene regulatory interactions control cell fate decisions. (nature.com)
This implies that bulk expression measurements are often misleading, thus necessitating methods for studying gene regulation in single cells. (nature.com)
The most common approach in such studies is to grow cells on a surface while tracking gene expression and growth using quantitative fluorescence time-lapse microscopy (QFTM). (nature.com)
which means both copies of the gene in each cell have mutations. (medlineplus.gov)
We compared the power of gene expression measurements with that of conventional prognostic markers, i.e., clinical, histo- pathological, and cell biological parameters, for predicting distant metastases in breast cancer patients using both established prognostic indices (e.g., the Nottingham Prognostic Index (NPI)) and novel combinations of conventional markers. (lu.se)

MSCs were obtained from the bone marrow (BM) cells remaining in the bag and filter used in the transplantation of hematopoietic stem cells. (springer.com)
We have successfully laminated rat myocardial cell sheets to produce artificial tissue with a high cell density that beats autonomously after transplantation into the rat [1]. (heraldopenaccess.us)
Transplantation of pancreatic islet cells into patients with type 1 DM, as a means of enabling these individuals to produce their own insulin, has been under investigation. (medscape.com)

The developed DNA vectors encoded mature snoRNAs or artificial pre-mRNA fragments that were processed to snoRNA [ 1 , 13 ]. (hindawi.com)

We will address how repurposing of biological and synthetic components can be used to create artificial cells for development in areas such as fuel production, drug delivery and environmental remediation. (royalsociety.org)

The growth is primarily driven by several variables about which Regional Research Reports provides comprehensive insights and estimation in the global ?stem cell artificial meat market research. (regionalresearchreports.com)
The competitive profiles of the top vendors of ?stem cell artificial meat products and their most recent developments are also included in the report. (regionalresearchreports.com)
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The global ?stem cell artificial meat market report also includes annual growth rates for each segment. (regionalresearchreports.com)
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Additionally, it details the market's competitive landscape for all significant players identified in the global ?stem cell artificial meat market. (regionalresearchreports.com)
The report also outlines the challenges facing the global ?stem cell artificial meat market. (regionalresearchreports.com)
The quest for artificial meat inches forward-the company Memphis Meats announced today it has developed chicken and duck meat from cultured cells of each bird, producing "clean poultry. (newstimenow.com)
Cell immortalization is a critical component of artificial meat technology, enabling the scalable and sustainable production of cultured meat products. (amzeal.com)
ALBANY, N.Y. - Amzeal -- The global demand for sustainable and cruelty-free protein sources has led to significant advancements in the field of artificial meat, also known as cultured or lab-grown meat. (amzeal.com)
In this article, we will explore the role of cell immortalization in artificial meat technology and provide insights into the market trends and forecasts. (amzeal.com)
Immortalized cell lines serve as the foundation for the production of cultured meat, making it a sustainable and ethical alternative to traditional livestock farming. (amzeal.com)
Sustainable Meat Production: Cell immortalization reduces the need for continuous animal breeding and slaughtering, resulting in a more environmentally sustainable and humane approach to meat production. (amzeal.com)
Quality Control: Immortalized cell lines provide a consistent source of high-quality cells, ensuring uniformity in the final meat product, including its taste, texture, and nutritional profile. (amzeal.com)
Reduced Production Time: Immortalized cells grow rapidly, significantly reducing the time required to produce cultured meat compared to traditional livestock farming. (amzeal.com)
Investment and Research: The artificial meat industry has seen a surge in investment from both private and public sectors. (amzeal.com)
These partnerships aim to leverage the expertise of each entity to advance artificial meat technology, including cell immortalization methods. (amzeal.com)

Heeger says that his team's is the first double-layer organic solar cell that can be manufactured by painting polymers on top of each other. (sciencenews.org)

First, we know that we have pancreases and beta-cell transplants that work. (medscape.com)
A cluster of mucormycosis infections in patients with hematologic malignancies, stem cell transplants, and solid organ transplants. (cdc.gov)

It's essentially a two-solar cell sandwich with a transparent film in the middle. (sciencenews.org)
That's a record for organic solar cells, say Alan Heeger of the University of California, Santa Barbara and his colleagues in the July 13 Science . (sciencenews.org)
image: Simulated sunlight powers a solar cell that converts atmospheric carbon dioxide directly into syngas. (eurekalert.org)
Unlike conventional solar cells, which convert sunlight into electricity that must be stored in heavy batteries, the new device essentially does the work of plants, converting atmospheric carbon dioxide into fuel, solving two crucial problems at once. (eurekalert.org)
A solar farm of such "artificial leaves" could remove significant amounts of carbon from the atmosphere and produce energy-dense fuel efficiently. (eurekalert.org)
The new solar cell is not photovoltaic -- it's photosynthetic," says Amin Salehi-Khojin, assistant professor of mechanical and industrial engineering at UIC and senior author on the study. (eurekalert.org)

Phospholipid membranes are an obvious choice as compartmentalizing boundaries, as they act as selective barriers in all living biological cells. (wikipedia.org)
Biological cells can perform complex functions, but are difficult to controllably engineer. (healthwnews.com)

Over a period of six to eight weeks, the cells replicate, filling in the spaces between the fibers to form a solid tissue. (dukehealth.org)

They grew from skin and heart stem cells into tissue clumps of several hundred cells that moved in pulses generated by heart muscle tissue, said lead study author Sam Kriegman, a doctoral candidate studying evolutionary robotics in the University of Vermont's Department of Computer Science, in Burlington. (livescience.com)
Skin cells held the xenobots together, and the beating of heart tissue in specific parts of their "bodies" propelled the 'bots through water in a petri dish for days, and even weeks at a stretch, without needing additional nutrients, according to the study. (livescience.com)
T. Twellmann, T.W. Nattkemper, W. Schubert, H. Ritter, Cell detection in micrographs of tissue sections using support vector machines, in: Proceedings of the ICANN: workshop on Kernel & Subspace Methods for Computer Vision, Vienna, Austria, 2001, pp. 79–88. (crossref.org)
We are optimistic that our approach represents an initial proof of principle for in vivo regeneration of an entire three-dimensional tissue, like the skin, not just individual cell types. (singularityhub.com)
Our group has investigated the use of cell sheet engineering to regenerate myocardial tissue. (heraldopenaccess.us)
We can now start to scale up basic cell technologies into larger tissue-scale networks, with precise control over the kind of architecture we create. (healthwnews.com)

Once a mammalian egg has been fertilised by a sperm, it divides multiple times to generate a small, free-floating ball of stem cells. (cam.ac.uk)
According to Professor Pasque, these cells generate the first blood in an embryo, help to attach the embryo to the future placenta and play a role in forming the primitive umbilical cord. (nutsel.com)

There are really two different kinds of cells we're concerning ourselves with - smooth muscle cells which are the cells that make up the wall of the blood vessel and make the protein-like collagen that gives it mechanical strength. (dukehealth.org)
Amazingly, this can be accomplished without any direct human intervention thanks to a first-of-its-kind artificial protein - designed on a computer and synthesized in the lab - that can be used to build brand-new biological circuits inside living cells. (ucsf.edu)
It is found in foods that contain protein and in some artificial sweeteners. (medlineplus.gov)

b) Base-pairing interactions between an artificial box C/D RNA and target RNAs. (hindawi.com)

In particular, the present invention provides an improved method for the formation of pancreatic endoderm, pancreatic hormone expressing cells and pancreatic hormone secreting cells. (patsnap.com)
Disclosed herein are cell cultures comprising PDX1-positive endoderm cells and methods of producing the same. (patsnap.com)
Also disclosed herein are cell populations comprising substantially purified PDX1-positive endoderm cells as well as methods for enriching, isolating and purifying PDX1-positive endoderm cells from other cell types. (patsnap.com)

Organized collagen fibrils, observed associated with the cell hydroxyapatite (HAp) crystals, were found throughout the spheroid and in between the collagen fibrils. (ntnu.no)

2014). Human NK cells: From surface receptors to the therapy of leukemias and solid tumors. (springer.com)

First author Dr Can Xu, Research Associate at the University of Bristol, added: "Our living-material assembly approach provides an opportunity for the bottom-up construction of symbiotic living/synthetic cell constructs. (nanowerk.com)

We found that transfection of artificial box C/D snoRNA analogues directed to HSPA8 pre-mRNAs into human cells induced suppression of the target mRNA expression in a time- and dose-dependent manner. (hindawi.com)
A natural question is: "What happens when you begin using human cells? (dukehealth.org)
Biologists Create New Human Cells: Artificial Humans? (nutsel.com)
Natural human cells serve as the body's building blocks, absorb nutrients from meals, transform those nutrients into energy, and perform certain functions. (nutsel.com)
A recent study, published in the journal Cell Stem Cell by Professor Vincent Pasque and his colleagues at KU Leuven, used stem cells to create new human cells in the lab , possibly marking the beginning of making artificial humans. (nutsel.com)

Now, a team of bioengineers led by UC San Francisco's Hana El-Samad, PhD, and the University of Washington's David Baker, PhD, have devised a remarkable solution to this problem - "smart" cells that behave like tiny autonomous robots which, in the future, may be used to detect damage and disease, and deliver help at just the right time and in just the right amount. (ucsf.edu)

In a similar way, functional biological building blocks can be encapsulated in these lipid compartments to achieve the synthesis of (however rudimentary) artificial cells. (wikipedia.org)
Corresponding author Professor Stephen Mann said: "Achieving high organisational and functional complexity in synthetic cells is difficult especially under close-to-equilibrium conditions. (nanowerk.com)

Being able to create and control this process paves the way for more complex programming, making the engineered cells suitable for more advanced tasks. (innovationtoronto.com)
Cell phones equipped with speech-recognition software applications, such as Siri or Google Assistant, are everyday examples of technologies that can perform non-routine and higher-order 'thinking'-based tasks [3]. (cdc.gov)

So far, no completely artificial cell capable of self-reproduction has been synthesized using the molecules of life, and this objective is still in a distant future although various groups are currently working towards this goal. (wikipedia.org)
Cells are naturally equipped to sense chemicals and to produce organic molecules. (innovationtoronto.com)
A 'key' (black) unlocks a 'cage' (grey), revealing a bioactive peptide (yellow) which can interact with other molecules in the cell. (ucsf.edu)

Importantly, no integration of the HAC DNA was observed in the hESc lines, compared with the fibrosarcoma-derived control cells, where the exogenous DNA frequently integrated in the host genome. (nih.gov)

The main challenge for the success of this approach is to obtain a great quantity of activated NK cells for adoptive transfer. (springer.com)

Artificial chicken grown from cells gets a taste test-but who will regulate it? (newstimenow.com)

A bottom-up approach to build an artificial cell would involve creating a protocell de novo, entirely from non-living materials. (wikipedia.org)

A postdoctoral research associate in my lab, Masakazu Kurita , who has a background in plastic surgery, knew that a critical step in wound healing was the migration of stem-cell-like cells called basal keratinocytes-from nearby, undamaged skin-into wounds. (singularityhub.com)
Basal keratinocytes are precursors to many different types of skin cells. (singularityhub.com)
We wanted to convert these mesenchymal cells into basal keratinocytes, without ever taking them out of the body. (singularityhub.com)

Anatomy4

Diseases2

Psychiatry and Psychology1

Phenomena and Processes7

Disciplines and Occupations2

Technology, Industry, Agriculture2

Health Care2

20233

Intelligence22

Vitro14

Neural8

Embryonic Stem3

Scientists14

Differentiation7

Researchers19

Antigen present2

Cell's6

Development of artificial2

Mammalian cells3

Proteins7

Photovoltaic cells1

Endothelial cells5

Structures7

Immunotherapy4

Tissues7

Mimic2

Molecular5

Mimics3

AAPCs2

Neurons3

Processes10

Nucleus2

Approaches2

Flow Cytometry1

Membrane2

Proliferation3

Organs2

Stem cell res3

Biology5

Bacterial3

Gene9

Transplantation3

Vectors1

Create artificial1

Meat17

Polymers1

Transplants2

Solar6

Biological cells2

Replicate1

Tissue6

Generate2

Protein3

Interactions1

Endoderm3

Crystals1

Receptors1

Constructs1

Human cells5

Autonomous1

Functional2

Tasks2

Molecules3

Exogenous1

Adoptive transfer1

Grown1

Protocell1

Basal3