• Examples
  • Examples include: Aminoquinuride benzonidazole blasticidin S DAPI diminazene diminazene aceturate eflornithine ethidium isometamidium chloride lonidamine melaminylthioarsenate melarsoprol nifurtimox pentamidine posaconazole puromycin quinapyramine salicylhydroxamic acid suramin tetraphenylporphine sulfonate Trypanosomiasis vaccine Trypanocidal Agents at the US National Library of Medicine Medical Subject Headings (MeSH) MeSH list of agents 82014344 GOBLE, F. C. (January 1950). (wikipedia.org)
  • drug
  • For example, it appears that eflornithine, a drug used to treat trypanosomiasis, inhibits ornithine decarboxylase, while the aminoglycoside antibiotic/antiprotozoals used to treat leishmaniasis are thought to inhibit protein synthesis. (wikipedia.org)
  • Find
  • Because of the side-effects and the resistance that pathogenic protozoa build against the standard antiparasitic drugs, e.g., metronidazole, much recent attention has been paid to plants used in traditional medicine around the world in order to find new antiprotozoal agents. (mdpi.com)
  • activity
  • showed the more significant antiprotozoal activity (91.54% and 90.50% growth inhibition at a concentration of 150 µg/mL with IC 50 values of 59.14 and 60.07 µg/mL, respectively). (mdpi.com)
  • Bioassay-guided fractionation of the methanolic extracts from these two plants afforded carvacrol ( 1 ) and chalepensin ( 2 ), respectively, as bioactive compounds with antiprotozoal activity. (mdpi.com)