• Fluorouracil is an antineoplastic anti-metabolite. (pharmacycode.com)
  • Fluorouracil Cream USP is topical preparations containing the fluorinated pyrimidine 5-fluorouracil, an antineoplastic antimetabolite. (nih.gov)
  • It is a purine nucleoside antimetabolite . (bionity.com)
  • FLUDARA (fludarabine) FOR INJECTION should be administered under the supervision of a qualified physician experienced in the use of antineoplastic therapy. (rxlist.com)
  • The antimetabolite gemcitabine remains part of the standard of care but shows very limited antitumor efficacy. (nih.gov)
  • Antineoplastic agents inhibit cell growth and proliferation. (medscape.com)
  • Antimetabolite agents are used to terminate pregnancy. (medscape.com)
  • Drugs used to manage connective tissue disease (CTD) associated with interstitial lung disease (ILD) (CTD-ILD) include nintedanib, corticosteroids, and antineoplastic agents. (medscape.com)
  • Methotrexate is an antineoplastic agent that inhibits cell proliferation by destroying rapidly dividing cells. (medscape.com)
  • Ox)aliplatin - a platinum-based alkylating antineoplastic agent. (wikipedia.org)
  • An antimetabolite antineoplastic agent with immunosuppressant properties. (online-medical-dictionary.org)
  • Azacytidine has been used as an antineoplastic agent. (umassmed.edu)
  • It is an antimetabolite and antineoplastic agent. (transparencymarketresearch.com)
  • An antineoplastic agent, it is used in the treatment of myeloid leukaemia. (pharmakb.com)
  • It has a role as an antineoplastic agent. (pharmakb.com)
  • Cisplatin is a platinum-containing compound that exerts an antineoplastic effect by covalently binding to DNA, with preferential binding to N-7 position of guanine and adenosine. (medscape.com)
  • An antineoplastic compound which also has antimetabolite action. (nih.gov)
  • Ataxia telangiectasia and Rad3-related protein (ATR), the apical kinase of the intra-S-phase DNA damage response, plays a central role in safeguarding cells from replication stress and can therefore limit the efficacy of antimetabolite drug therapies. (nih.gov)
  • In popular usage, it usually refers to antineoplastic drugs used to treat cancer or the combination of these drugs into a standardized treatment regimen . (wikidoc.org)
  • Hydroxyurea belongs to the group of cancer-fighting medications known as antineoplastics , and specifically to the group of antineoplastics known as antimetabolites . (medbroadcast.com)
  • Antimetabolites that are useful in cancer chemotherapy. (bvsalud.org)
  • The cellular kinetics of particular cancers is an important consideration in the design of antineoplastic drug regimens and may influence the dosing schedules and timing intervals of treatment. (msdmanuals.com)
  • Antineoplastic with alkylating activity. (cancer.gov)
  • Intrathecal methotrexate is an antimetabolite that inhibits dihydrofolate reductase, thereby hindering DNA synthesis and cell reproduction in malignant cells. (medscape.com)
  • Methotrexate (MTX) is an antineoplastic antimetabolite and folic acid analogue and antagonist with antineoplastic and immunosuppressive properties from interfering with the synthesis and cellular replication of DNA. (e-lactancia.org)
  • Methotrexate is an antimetabolite, which inhibits DHFR resulting in decreased immune function and antineoplastic activity and is FDA approved for psoriasis, RA, and several cancers including choriocarcinoma, AML, lung, head and neck and epidermoid (FDA.gov). (jax.org)
  • Antimetabolite that inhibits dihydrofolate reductase, thereby hindering DNA synthesis and embryonic cell reproduction. (medscape.com)
  • It is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. (absource.de)
  • Hydroxyurea is an antineoplastic (anti-cancer) agent used to treat melanoma , resistant chronic myelocytic leukemia , and recurrent , metastatic, or inoperable carcinoma of the ovary and primary squamous cell (epidermoid) carcinomas of the head and neck. (rxlist.com)
  • Cytarabine is an antineoplastic anti-metabolite used in the treatment of several forms of leukemia including acute myelogenous leukemia and meningeal leukemia. (pharmacycode.com)
  • Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures. (lookformedical.com)
  • Classic antimetabolite anticancer drug with chemical structure similar to endogenous intermediates or building blocks of DNA or RNA synthesis. (medscape.com)
  • Gemcitabine belongs to the group of cancer-fighting medications known as antineoplastics , and specifically to the group of antineoplastics known as antimetabolites . (medbroadcast.com)
  • Thus, future antineoplastic treatments could combine the modulation of the microbiome and its products with immunotherapeutics and more conventional approaches that directly target malignant cells. (nature.com)
  • Doxorubicin is an anthracycline antineoplastic that causes DNA strand breakage through effects on topoisomerase II and direct intercalation into DNA, which causes DNA polymerase inhibition. (medscape.com)
  • The prominent adverse effects of antineoplastic drugs are exerted on rapidly proliferating normal tissues, in addition, to their chronic and cumulative toxicities. (pharmacy180.com)
  • It has antineoplastic properties, including inhibition of angiogenesis and induction of APOPTOSIS. (nih.gov)
  • The cellular kinetics of particular cancers is an important consideration in the design of antineoplastic drug regimens and may influence the dosing schedules and timing intervals of treatment. (msdmanuals.com)
  • An antineoplastic antimetabolite with immunosuppressant properties. (clustermed.info)
  • Bacterial products that have potential antineoplastic or immunostimulatory properties include bacterial toxins, microbial ligands of pattern recognition receptors, as well as bacterial metabolites, including butyrate, polyamines and pyridoxine. (nature.com)