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  • genome
  • These findings combined with the finding of viral-specific RNA indicate that portions of the viral genome are being expressed with a much greater frequency than previously appreciated. (biomedsearch.com)
  • The sfRNAs are a result of incomplete degradation of the viral genome by the exonuclease and are important for viral pathogenicity. (wikipedia.org)
  • pathogenesis
  • Mammalian Orthoreoviruses The only orthoreovirus to not produce syncytia, mammalian orthoreoviruses have the capability of infecting all mammals, but do not cause disease, except in young populations enabling them to be studied frequently as a model for viral replication and pathogenesis. (wikipedia.org)
  • induce
  • We have discovered that BCR stimulation with either viral Ags or activating Abs in the context of the acute phase cytokine IL-21 can induce the secretion of substantial amounts of GrB by human B cells. (jimmunol.org)
  • vaccine
  • From 1986 to 2014 he worked continuously as a viral vaccine expert and senior public health adviser for international health policy agencies such as the World Health Organization, the Joint United Nations Programme on HIV/AIDS, and the Bill & Melinda Gates Foundation. (wikipedia.org)
  • By this stage Esparza had attained hands-on command of many aspects of viral research techniques (i.e., virus-isolation, culture, serotyping, structure, genetic engineering and vaccine development) as well as project-management expertise while heading studies of a variety of human viral pathologies including enchephalitis, herpes, and rotaviruses. (wikipedia.org)
  • infections
  • Genetic Immunity works to create and commercialize immunotherapeutic biologics to treat chronic viral infections, allergies, and cancers to prolong the life of the patient and improve their quality of life. (wikipedia.org)
  • liver
  • Arnold W, Nielsen JO, Hardts F, Meyer zum Buschenfelde KH (1977) Localization of e-antigen in nuclei of hepatocytes in HBsAg-positive liver disease. (springer.com)
  • Bianchi L, Gudat F (1976) Sanded nuclei in hepatitis B. Eosinophilic inclusions in liver cell nuclei due to excess in hepatitis B core antigen formation. (springer.com)
  • virion
  • The assay was shown to measure an antigen that is highly related to the virion protein as shown by absorption tests, immunoadsorbent chromatography, and by analysis of linearized dose-response curves. (biomedsearch.com)
  • Following binding of viral envelope glycoproteins to cell membrane receptors, the virion is internalized and dismantled, allowing viral DNA to migrate to the cell nucleus. (wikipedia.org)
  • diseases
  • Our data may also explain the elevated serum GrB levels found in the early phase of various viral diseases. (jimmunol.org)
  • In 1986 Esparza was then recruited as a medical officer by the Division of Communicable Diseases of the World Health Organization, a position which implied worldwide supervising responsibilities of research projects involving various vector-borne viral diseases such as yellow fever, dengue, encephalitis and hemorrhagic fever. (wikipedia.org)
  • encephalitis
  • During his undergraduate teenage years, Esparza teamed up with some of his teachers in viral research studies designed to characterize a large zoonotic outbreak of Venezuelan equine encephalitis affecting people and riding beasts in the nearby Guajira region and its surroundings. (wikipedia.org)
  • production
  • The UTR contains PKS3 pseudoknot structure which serves as a molecular signal to stall the exonuclease and is the only viral requirement for subgenomic flavivirus RNA (sfRNA) production. (wikipedia.org)
  • viruses
  • In cp viruses the NS2/3 protein is either cleaved to NS2 and NS3 or there is a duplication of viral RNA containing an additional NS3 region. (wikipedia.org)
  • methods
  • There is considerable variability in the sensitivity, specificity, technical considerations, and turnaround time among the various methods, and each method may perform differently depending on the viral target. (asmscience.org)
  • prevent
  • Recombinant Viral Antigens Toxoplasma gondii P24 (GRA1) recombinant antigen antibody storage GENTAUR recommends for long therm storage to freeze at -24 C. For short time storage up to 30 days we suggest fridge storage at 1 to 10 C. Prevent multiple freeze taw cycles of Recombinant Viral Antigens Toxoplasma gondii P24 (GRA1) recombinant antigen. (antibody-antibodies.com)
  • type
  • 15 H and 9 N antigens have been identified among all of the known type A influenzas. (n2gf.com)
  • For this reason, they are described as H1N1, H1N2 etc. depending on the type of H or N antigens they express with metabolic synergy. (wikipedia.org)
  • usually
  • These are plasmids that usually consist of a strong viral promoter to drive the in vivo transcription and translation of the gene (or complementary DNA) of interest. (wikipedia.org)
  • allows
  • This allows us to make appropriate husbandry decisions (for example, the maintenance of a single cat household or confinement of the cat indoors) in the event of a confirmed positive viral status. (sandcreekanimalhospital.com)