• lymphocytes
  • CD56+CD3− lymphocytes express CD40L after incubation with IL-2. (nih.gov)
  • Staining profiles of o.n. cultured lymphocytes, obtained as indicated in the Materials and Methods section, by using PE-labeled antiCD40L TRAP-1, FITC-labeled anti-CD3, or anti-CD56 mAbs in a classical double fluorescence assay. (nih.gov)
  • tumors
  • HuN901 conjugated with the maytansinoid N 2′ -deacetyl- N 2′ -(3-mercapto-1-oxopropyl)-maytansine (DM1), a potent antimicrotubular cytotoxic agent, may provide targeted delivery of the drug to CD56 expressing tumors. (aacrjournals.org)
  • Synaptophysin
  • Immunohistochemically, prostatic small cell carcinoma are positive for thyroid transcription factor 1 (TTF-1), CD56, chromogranin A, synaptophysin, neuron-specific enolase, calcitonin and bombesin/gastrin-releasing peptide, while lacking, or rarely and weakly expressing, androgen receptor and prostate-specific antigen. (wikipedia.org)
  • neural
  • Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). (novusbio.com)
  • markers
  • Although the antigen is particularly common in carcinoid tumours, it is found in such a wide range of other conditions that it is of less use in distinguishing these tumours from others than more specific markers such as chromogranin and NSE. (wikipedia.org)
  • expression
  • We also assessed the expression of CD40L on polyclonal NK effectors derived from peripheral blood of normal donors, by double staining with anti-CD40L mAb TRAP-1 and anti-CD3 or anti-CD56 mAb. (nih.gov)
  • human
  • CD56 Human Recombinant (aa 20-220) expressed in E.coli, shows a 48 kDa band on SDS-PAGE. (promab.com)
  • In vivo antitumor activity of huN901-DM1 was then studied in a tumor xenograft model using a CD56 + OPM2 human MM cell line in SCID mice. (aacrjournals.org)
  • specific
  • They are negative for androgen receptor and prostate-specific antigen (PSA) and are positive for prostate acid phosphatase. (wikipedia.org)