• Newer antidepressants, such as serotonin selective reuptake inhibitors (SSRIs) and venlafaxine, have a wider therapeutic index than the older tricyclic antidepressants. (nih.gov)
  • ABSTRACT: Experimental data have suggested that in neuropathic pain, tricyclic antidepressants may work solely through a β2-agonist action. (sdu.dk)
  • β2-agonism seems not to be an important mechanism of action of tricyclic antidepressants in neuropathic pain. (sdu.dk)
  • Tricyclic antidepressants, serotonin-norepinephrine reuptake inhibitors, and gabapentinoids have some evidence for efficacy in central neuropathic pain. (wustl.edu)
  • Compared to tricyclic antidepressants, these tend to be stronger antihistamines and have less anticholinergic side effects. (drugbank.com)
  • Selective serotonin reuptake inhibitors versus tricyclic and heterocyclic antidepressants: comparison of drug adherence. (ox.ac.uk)
  • SELECTION CRITERIA: Parallel group randomised controlled trials comparing selective serotonin reuptake inhibitors with tricyclic or heterocyclic antidepressants in people with depression. (ox.ac.uk)
  • Tricyclic antidepressants may cause your body to process your other medicine differently. (webmd.com)
  • A review of the cardiovascular effects and toxicity of tricyclic antidepressants. (webmd.com)
  • Molecular features affecting the potency of tricyclic antidepressants and structurally related compounds as inhibitors of the uptake of tritiated norepinephrine by rabbit aortic strips. (webmd.com)
  • Although serotoninergic agents such as antidepressants have been shown to increase neurogenesis, the effects of MnRN lesions remain to be elucidated. (fapesp.br)
  • Westenberg, H. G.M. / Anxiety disorders : A review of tricyclic antidepressants and selective serotonin reuptake inhibitors . (tau.ac.il)
  • Treatment options include anticholinergics, antispasmodic agents, and tricyclic antidepressants (TCAs). (medscape.com)
  • In the following decades, the monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants were introduced. (beatcfsandfms.org)
  • The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition. (illumina.com)
  • Toxic manifestations of amoxapine overdosage differ significantly from those of other tricyclic antidepressants. (genelabs.com)
  • Barbiturates like butabarbital may increase the metabolism of tricyclic antidepressants like amoxipine. (genelabs.com)
  • Monitor for decreased therapeutic effects of tricyclic antidepressants if a barbiturate is initiated/dose increased, or increased effects if a barbiturate is discontinued/dose decreased. (genelabs.com)
  • Barbiturates such as butalbital may increase the metabolism of tricyclic antidepressants amoxapine. (genelabs.com)
  • Tricyclic antidepressants and carbamazepine have become the mainstay in the treatment of neuropathic pain. (omeka.net)
  • Overall, Amitriptyline and Clomipramine, the two tricyclic antidepressants, had higher immunomodulatory capacities than the two selective serotonin reuptake inhibitors Citalopram and Paroxetine. (mnhn.fr)
  • As a nootropic , and for cognitive health, St. John's wort is as effective at relieving mild-to-moderate depression as the most commonly prescribed SSRI and TCA (tricyclic) antidepressants. (nootropicsexpert.com)
  • Mildly depressed patients were often not good candidates for the tricyclic antidepressants used since the 1950s, or didn't want to risk the potentially severe side-effects of monoamine oxidase inhibitors. (medicaltuesday.net)
  • or exp serotonin uptake inhibitors/ or exp serotonin agents/ or (selective serotonin reuptake inhibitors or SSRI? (nationalacademies.org)
  • BACKGROUND: Selective serotonin reuptake inhibitors are thought to have better discontinuation rates (i.e. less people dropping out) than tricyclic and heterocyclic antidepressant drugs. (ox.ac.uk)
  • OBJECTIVES: To assess the comparative tolerability of selective serotonin reuptake inhibitors and tricyclic/heterocyclic antidepressant drugs. (ox.ac.uk)
  • The selective serotonin reuptake inhibitors showed less participants dropping out compared to the tricyclic/heterocyclic group (odds ratio 1.21, 95% confidence interval 1.12 to 1.30). (ox.ac.uk)
  • REVIEWER'S CONCLUSIONS: Whilst selective serotonin reuptake inhibitors do appear to show an advantage over tricyclic drugs in terms of total drop-outs, this advantage is relatively modest. (ox.ac.uk)
  • This has implications for pharmaco-economic models, some of which may have overestimated the difference of drop-out rates between selective serotonin reuptake inhibitors and tricyclic antdepressants. (ox.ac.uk)
  • Paroxetine HCl is an antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). (csnpharm.cn)
  • A panel convened in November 2010 found that among the currently recommended analgesic products for arthritis-related pain, fixed-low-dose combination products hold promise for pain control because such products allow lower doses of individual agents resulting in decreased toxicity and acceptable efficacy due to synergy between the individual drugs. (openrheumatologyjournal.com)
  • Atazanavir may increase the effect and toxicity of the tricyclic antidepressant, amoxapine, by decreasing its metabolism. (genelabs.com)
  • Imipraminoxide (brand names Imiprex, Elepsin), or imipramine N-oxide, is a tricyclic antidepressant (TCA) that was introduced in Europe in the 1960s for the treatment of depression. (wikipedia.org)
  • A tricyclic antidepressant used in the treatment of neurotic or reactive depressive disorders and endogenous or psychotic depression. (drugbank.com)
  • Add-on polytherapy with antidepressant agents was reviewed in 42 inpatients with major depression diagnosed according to the ICD-10 criteria. (elsevierpure.com)
  • Clinically, not every patient with major depression can tolerate the adverse side effects induced by an effective dose of a single tricyclic antidepressant. (elsevierpure.com)
  • Although single drugs in one or two classes were available for the treatment of depression several decades ago, multiple therapeutic modalities now exist, often with many agents within each class. (beatcfsandfms.org)
  • So, the effects of MnRN lesion on hippocampal neurogenesis in animals chronically stressed and treated or not with Imipramine (a tricyclic antidepressant) will be investigated too. (fapesp.br)
  • Imipramine is a tricyclic antidepressant that possesses anti-inflammatory activity and has been reported to inhibit the progression of highly metastatic non-small cell lung cancer. (bvsalud.org)
  • OR exp anti-anxiety agents/ or exp antipsychotic agents/ OR exp Anticonvulsants/ OR exp Serotonin Reuptake Inhibitors/ or exp Tricyclic Antidepressant Drugs/ or Adrenergic Blocking Drugs/ or exp neuroleptic Drugs/ or exp Anticonvulsive Drugs/) Psychotherapies Set (exp psychotherapy/ or psychotherap$.ti,ab. (nationalacademies.org)
  • Venlafaxine HCl is an inhibitor of serotonin/noradrenalin re-uptake and is used as an antidepressive agent. (csnpharm.cn)
  • A third group ( ANTIDEPRESSIVE AGENTS, SECOND-GENERATION ) is a diverse group of drugs including some that act specifically on serotonergic systems. (online-medical-dictionary.org)
  • 2.Ghose K. Sympathomimetic amines and tricyclic antidepressant drugs. (webmd.com)
  • Sympathomimetic drugs, estrogen, and tricyclic agents increase bladder outlet resistance to improve symptoms of stress urinary incontinence. (medscape.com)
  • Because of the potential for drowsiness-especially when combined with alcohol, sedatives, or hypnotic drugs-these agents may impair the patient's ability to perform hazardous activities, such as driving or operating heavy machinery. (medscape.com)
  • SSRIs bind with significantly less affinity to histamine, acetylcholine, and norepinephrine receptors than tricyclic antidepressant drugs. (illumina.com)
  • Doxepin HCl, a tricyclic antidepressant, is antagonist of histamine H1 Receptor (Kd = 310 pM) and histamine H4 receptor (pKi = 6.79). (csnpharm.cn)
  • Anticholinergic agents inhibit the binding of acetylcholine to the cholinergic receptor, thereby suppressing involuntary bladder contraction of any etiology. (medscape.com)
  • Amoxapine, the N -demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative tricyclic antidepressant (TCA). (genelabs.com)
  • Amoxapine is a tricyclic antidepressant of the dibenzoxazepine class, chemically distinct from the dibenzodiazepines, dibenzocycloheptenes, and dibenzoxepines. (genelabs.com)
  • Antidepressive Agents, Second-Generation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)
  • Interactions between sympathomimetic amines and antidepressant agents in man. (webmd.com)
  • Potential adverse effects of all anticholinergic agents include blurred vision, dry mouth, heart palpitations, drowsiness, and facial flushing. (medscape.com)
  • More careful assessment of the efficacy of an agent at early and regular intervals, with early revision of the treatment modality if it is not optimal, is an important new guideline that applies not only to somatic treatments, but also to psychotherapeutic approaches and combination psychotherapy-pharmacotherapy when treatment is not proceeding optimally. (beatcfsandfms.org)
  • A metabolite of AMITRYPTYLINE that is also used as an antidepressive agent . (dictionary.net)
  • This graph shows the total number of publications written about "Antidepressive Agents, Second-Generation" by people in this website by year, and whether "Antidepressive Agents, Second-Generation" was a major or minor topic of these publications. (uchicago.edu)
  • Below are the most recent publications written about "Antidepressive Agents, Second-Generation" by people in Profiles. (uchicago.edu)
  • Nineteen (67.8%) patients of the polytherapy group were treated with a dosage equivalent to 150 mg/day of tricyclic antidepressant. (elsevierpure.com)
  • The tricyclic antidepressant dosage will likely need to be increased during concomitant barbiturate therapy, and reduced upon barbiturate discontinuation. (genelabs.com)
  • Managing pain from chronic conditions, such as, but not limited to, osteoarthritis and rheumatoid arthritis, requires the clinician to balance the need for effective analgesia against safety risks associated with analgesic agents. (openrheumatologyjournal.com)
  • Your tricyclic antidepressant may increase the effects of your other medicine. (webmd.com)
  • 3.Svedmyr N. The influence of a tricyclic antidepressive agent (protriptyline) on some of the circulatory effects of noradrenaline and adrenaline in man. (webmd.com)
  • These agents are beneficial in the treatment of mild to moderately severe stress incontinence in women. (medscape.com)
  • Therefore, this review intends to provide specific and clinically useful information regarding the effects of fluoxetine for depression compared with tricyclics (TCAs), SSRIs, serotonin-noradrenaline reuptake inhibitors (SNRIs), monoamineoxidase inhibitors (MAOIs) and newer agents, and other conventional and unconventional agents. (ox.ac.uk)
  • The biogenic amine transporters (BATs) regulate endogenous neurotransmitter concentrations and are targets for a broad range of therapeutic agents including selective serotonin reuptake inhibitors (SSRIs), serotonin-noradrenaline reuptake inhibitors (SNRIs) and tricyclic antidepressants (TCAs). (cornell.edu)
  • Opipramol hydrochloride acts as an anxiolytic and antidepressant agent. (polpharma.com)
  • The increased risk was particularly notable for the selective serotonin-reuptake inhibitor (SSRI) paroxetine and the tricyclic antidepressant amitriptyline. (survivingantidepressants.org)
  • Propiomazine, an atypical antipsychotic agent, is used to treat both negative and positive symptoms of schizophrenia, acute mania with bipolar disorder, agitation, and psychotic symptoms in dementia. (drugbank.com)
  • TB351 trade name] is indicated in combination with other antituberculosis agents for the treatment of drug- resistant tuberculosis caused by Mycobacterium tuberculosis . (who.int)
  • SELECTION CRITERIA: All RCTs comparing fluoxetine with any other AD (including non-conventional agents such as hypericum) for patients with unipolar major depressive disorder (regardless of the diagnostic criteria used) were included. (ox.ac.uk)
  • The 2009 American College of Gastroenterologists (ACG) position statement on the management of irritable bowel syndrome noted that the antidiarrheal agent loperamide effectively reduced stool frequency and improved stool consistency, but it did not relieve pain, bloating, or other global irritable bowel syndrome symptoms. (medscape.com)
  • Unfortunately, we only found evidence comparing duloxetine with a handful of other active antidepressive agents and only a few trials per comparison were found (in some cases we retrieved just one trial). (cochrane.org)